• Journal of the Korean Society of Food Science and Nutrition
• /
• v.35 no.5
• /
• pp.583-587
• /
• 2006

Aqueous solutions of sugar alone or in the presence of lysine were gamma irradiated at 0, 5, 10, 20 and 30 kGy at room temperature. Absorbances at 284 nm as an indicator of intermediate stage of non -enzymatic browning reaction increased with irradiation dose in both the solution of sugar or lysine alone and sugar-lysine mixed solution. Absorbances at 420 nm as indicator of browning increased in the irradiated sugar-lysine mixed solutions although no browning was observed in the irradiated solution of sugar or lysine alone. The degree of browning of the irradiated sugar-lysine mixed solution increased with irradiation dose and was dependent on the type of sugar. For sugar-lysine mixed solution irradiated at 30 kGy, the browning had the following order of intensity: sucrose>fructose>arabinose>xylose>glucose. However, the sugar loss of irradiated sugar lysine mixed solution had a following order of intensity: glucose>fructose>sucrose>xylose>arabinose. The reducing power of the non-reducing sugar, sucrose, was produced by gamma irradiation. The present results indicated that gamma irradiation leads to a non-enzymatic browning reaction (carbonyl-amine reaction) in an aqueous system.

• Korean Journal of Digital Imaging in Medicine
• /
• v.12 no.1
• /
• pp.59-64
• /
• 2010

We examined the accuracy and efficiency of phantom by applying the designed phantom in order to check daily quality assurance easily by objective criteria and to confirm daily quality assurance of linear accelerator, simulator, and CT-simulator. The results of 10 weeks of linear accelerator output dose using American Association of Physicists in Medicine(AAPM) daily quality assurance guide were measured within ${\pm}1%$ of error. Mechanical check of laser alignment, optical distance indicator(ODI), CT scanner laser and alignment of gantry lasers with the center of imaging plane were measured within ${\pm}1mm$. Daily average working time for daily quality assurance of radiation therapy equipments was 38 minutes. The designed phantom was easy to install and daily quality assurance was possible with only one installation. The aspects reproducibility and efficiency as well as accuracy of quality assurance were excellent.

• 대한핵의학회:학술대회논문집
• /
• 2001.05a
• /
• pp.4-10
• /
• 2001

The radionuclide therapy is a protocol for tumor control by administering radionuclides as the cytotoxic agents. Radionuclides concentrated at the site of cancerous lesion are expected to kill the cancerous cells with minimal injury to the normal tissue. The efficacy of every radionuclide treatment can be evaluated by examining the toxicity to the lesion differentiated from that to the normal tissue. Radiation dosimetry is the procedure of quantitating the energy absorbed by target volumes of interest. Dosimetric information plays an indicator of the expected radiation damage and thus the therapeutic efficacy. This paper summarizes the dosimetric aspects in radionuclide therapy in terms of radionuclides of use, radiation dosimetry methodology and considerations for each treatment in practical use.

• Magazine of the Korean Society of Agricultural Engineers
• /
• v.45 no.3
• /
• pp.84-93
• /
• 2003

Photoreactivation of microorganism following UV-disinfection is one of the research topics of interest in assessing the UV-disinfection performance. Apparent photoreactivation was examined under fluorescent lamp and solar radiation as well as in darkness. Total coliform, fecal coliform, and Escherichia coli were used as indicator microorganisms, and their concentration was monitored with time after UV-disinfection. Under the darkness, their initial concentration of 10∼30 MPN/100 mL increased to the level of 100 MPN/100 mL after 24 hours, which implied that part of damaged microorganisms by UV-disinfection might be repairable with time. Under the fluorescent lamp, photoreactivation was more apparent that their concentration increased up to 1,000 MPN/100 mL which might significantly impair the water uses specially in reuse of reclaimed wastewater. However, their concentration further decreased down to below 2 MPN/100 mL under the solar radiation primarily due to additional disinfection by solar radiation rather than photoreactivation. Samples not disinfected by UV-disinfection also demonstrated substantial decrease of their concentration under solar radiation from about 5,000 MPN/100 mL to less than 30 MPN/100 mL in 24 hours. But direct reuse of effluent without disinfection is not recommended because natural decay by solar radiation may take time and be affected by climatic conditions. The result suggests that photoreactivation of pathogenic microorganisms may not be concerned in agricultural reuse of reclaimed wastewater because solar radiation may provide further disinfection after UV-disinfection.

• Journal of Korean Society for Atmospheric Environment
• /
• v.15 no.5
• /
• pp.545-554
• /
• 1999

We would like to develop a short-term model to predict the time-related concentration of ozone whose reaction mechanism is complex. The paper targets Seoul where an ozone alert system has recently been employed. In order to develop a short-term prediction model for ozone, we suggested the Ozone Peak Indicator(OPI), an equivalent of the potential daily maximum ozone concentration, with precursors being the only limiting factor, and we calculated the Ozone Peak Indicarot as OPI={$rac{(O_3)_{max}cdot(H_{eH})_{max}(Rad)_{max}$ to preclude the influence of mixing height and solar radiation on the daily maximum ozone concentration. The OPI on the day of the prediction is to be calcultated by using the relation between OPI and the initial value of precursors. The basic prediction formula for time-related ozone concentration was established as $O_3(1)={(OPI)cdot Rad(t-2)H_{eH}}$, using the OPI, solar radiation two hours before prediction and mixing height. We developed, along with the basic formula for predicting photochemical oxidants, "SEOM"(Seoul Empirical Oxidants Model), a Fortran program that helps predict solar radiation and mixing height needed in the prediction of ozone pollution. When this model was applied to Seoul and an analysis of the correlation between the observed and the predicted ozone concentrations was made through SEOM, there appeared a very high correlation, with a coefficient of 0.815. SEOM can be described as a short-term prediction model for ozone concentration in large cities that takes into account the initial values of precursors, and changes in solar radiation and mixing height. SEOM can reflect the local characteristics of a particular and region can yield relatively good prediction results by a simple data input process.t process.

• Journal of Korean society of Dental Hygiene
• /
• v.9 no.2
• /
• pp.111-124
• /
• 2009

This study analyzes through the review of literature and laws the exposure time, clinical frequency, and radiation exposure of intraoral and extraoral radiography as well as of panoramic radiography performed by dental hygienists in dental clinics, compares the dental radiology curriculums of radiological science and dental hygiene departments, and proposes the expansion of dental hygienists' radiography operations. The radiology curriculums were compared between the radiological science and dental hygiene departments of colleges. For new analysis by radiography for dental diagnosis, the exposure time, radiation absorbed dose, effective dose, and number of days of natural radiation were compared by the type of oral radiation films and radiographical techniques proposed by domestic and international studies. The exposure time of panoramic radiography is 15 seconds and it takes about two minutes for completion, whereas the exposure time of the standard radiography is 0.2~0.8 seconds and it takes 10 times longer for completion of the radiography of full mouth than the panoramic radiography. The standard radiography can cause distortions of radiation at severely curved parts of dental arch and palatopharyngeal reflex. However, panoramic radiography can be performed even for lock jaw patients, causes less inconvenience to patients and is much simpler than the standard radiography. The percentage of dental clinics where radiography is performed by dental hygienists was 92.0%, and the percentage of standard film radiography by dental hygienists was 98% whereas the percentage of panoramic radiography by dental hygienists was 92%. For the absorbed dose which is an indicator of radiation exposure, the When the effective dose which is an indicator of the danger of radiation exposure was converted to the number of days of natural radiation, it was 3.3 days for panoramic radiography, but 13.9 days for the full mouth standard radiography by bisecting angle technique which was 4.2 times longer than the panoramic radiography. There were two colleges that had a dental radiology course with two credits in the departments of radiological science. The credits for dental radiology courses in the department of dental hygiene ranged varied by college, ranging from 3 to 8; on average, the theory course was 2.2 credits and the practice course was 2.02 credits. To summarize the above results, the percentage of dental clinics where panoramic radiography is performed by dental hygienists under the guidance of dentists is high. Panoramic radiography has become an essential facility for dental clinics. It is faster than standard film radiography and less dangerous due to low radiation exposure. Panoramic radiography is a simple mechanical job that does not require training of oral radiography by radiotechnologist. Because panoramic radiography is one of major operations which must be performed at all times in dental clinics, it must be designated as intraoral technique rather than extraoral technique, or legalized for inclusion in the scope of operations of dental hygienists.

• Journal of Radiation Protection and Research
• /
• v.40 no.3
• /
• pp.168-173
• /
• 2015

The present investigation was planned to estimate potential possibility of striped field mice, Apodemus agrarius coreae (A. a. coreae), as a biological dosimeter in radio-environmental ecology. We bred captured wild A. a. coreae at laboratory and classified taxonomically based on external, cranial and tooth characters. Organ weights and splenocytic apoptosis were observed in order to establish a basic data on radiation biology of A. a. coreae (male, 40 weeks old). The biological effects was observed at 24hrs following irradiation (doses : 0, 0.5, 1, 2 Gy, dose rate : $0.8Gymin^{-1}$, $^{137}Cs$). Only thymus weights was significantly decreased. Splenocytic apoptosis was increased after irradiation. But splenocytic apoptosis was decreased in 0.5 Gy ${\gamma}$-irradiated mice compared to those of 0, 1, 2 Gy (P < 0.05). These data suggested that events in thymus and spleen of Korean dark-striped field mice, A. a. coreae THOMAS, could be a potential radio-biological indicator in human environments.

• Korean Journal of Veterinary Research
• /
• v.41 no.1
• /
• pp.99-104
• /
• 2001

To determine if micronucleus (MN) assay could be used to predict the absorbed dose of victims after accidental radiation exposure, we carried out to assess the absorbed dose depending on the numerical changes of MN in human peripheral blood lymphocytes after $^{60}Co\;{\gamma}-rays$ exposure in the range of 0.25 to 1 Gy, respectively. The MNs were observed at very low doses, and the numerical changes according to doses. Satisfactory dose-effect calibration curve is observed after low dose irradiation of human lymphocytes in vitro. When plotting on a linear scale against radiation dose, the line of best fit was $Y=(0.02{\pm}0.0009)+(0.033{\pm}0.010)D+(0.012{\pm}0.012)D^2$. The dose-response curve for MN induction immediately after irradiation was linear-quadratic and has a significant relationship between the frequencies of MN and dose. These data show a trend towards increase of the numbers of MN with increasing dose. The number of MN in lymphocytes that were observed in the control group is $0.1610{\pm}0.0093/cell$. Accordingly, MN assay in human peripheral lymphocytes could be a useful in viva model for studying radio-protective drug sensitivity or screening test, microdosimertic indicator and radiation-induced target organ injury. Since MN assay is simple, rapid and reproducible, it will also be a biodosimetric indicator for individual dose assessment after accidental exposure.

• Asian Pacific Journal of Cancer Prevention
• /
• v.15 no.14
• /
• pp.5889-5893
• /
• 2014

Over-expression of epidermal growth factor receptor (EGFR) has been identified as a common feature associated with clinical outcome in many types of cancer, including squamous cell carcinoma of the oesophagus (SCCO). However, the clinical importance of EGFR over-expression in SCCO remains unsettled as conflicting results exist. Therefore we carried out the present meta-analysis of published studies for clarification. A total of 13 studies including 1, 150 patients were enrolled. EGFR over-expression was positive in 722 of these cases. With EGFR over-expression, patients had higher depth of invasion, vascular invasion, and poor prognosis. However, expression had no relation with degree of differentiation, histological grade, lymph node metastasis, clinical stage or lymphatic invasion. EGFR over-expression is probably a valuable predictor for the T stage, vascular invasion and OS, and it could be used as a poor prognosis indicator for the esophageal SCC patients. Targeting therapy to EFGR should be considered to the combined treatment in SCCO.

• The Bulletin of The Korean Astronomical Society
• /
• v.40 no.1
• /
• pp.46.2-46.2
• /
• 2015

Modern methods in determining the value of the Hubble constant are divided into two main ways: the classical distance ladder method and the inverse distance ladder method. The classical distance ladder method is based on Cepheid calibrated Type Ia supernovae (SNe Ia), which are known as powerful distance indicator. The inverse distance ladder method uses cosmic microwave background radiation, which emitted from the high-z universe, and the cosmological model. Recent estimations of the Hubble constant based on these two methods show a $2{\sim}3{\sigma}$ difference, which called the "Hubble tension". It is currently an issue in the modern cosmology. We have been working on the luminosity calibration of SNe Ia based on the Tip of the Red Giant Branch (TRGB), which is a precise population I distance indicator. We present the TRGB distance estimates of 5 SNe Ia host galaxies with the archival Hubble Space Telescope image data. We derive the mean absolute maximum magnitude of 5 SNe Ia and the value of the Hubble constant. Cosmological implications of our estimate will be discussed.