• The Korean Journal of Physiology and Pharmacology
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• v.9 no.6
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• pp.341-346
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• 2005

The mechanism underlying oxidant-induced intracellular $Ca^{2+}$ ($[Ca^{2+}]_i$) increase was studied in cultured bovine aortic endothelial cells (BAECs) using fura-2 AM. In the presence of 2 mM extracellular $Ca^{2+}$, the application of DTBNP ($20{\mu}M$), a membrane-permeable oxidant, caused an increase in $[Ca^{2+}]_i$, and DTT (2 mM) as a reductant completely reversed the effect of DTBNP. The $[Ca^{2+}]_i$ increase induced by DTBNP was also observed in an extracellular $Ca^{2+}$-free/2 mM EGTA solution, indicating the release of $Ca^{2+}$ from intracellular store(s). After endoplasmic reticulum was depleted by an $IP_3$-generating agonist, ATP ($30{\mu}M$) or an ER $Ca^{2+}$ pump inhibitor, thapsigargin ($1{\mu}M$), DTBNP-stressed BAECs showed an increase of $[Ca^{2+}]_i$ in $Ca^{2+}$-free/2 mM EGTA solution. Ratio-differences before and after the application of DTBNP after pretreatment with ATP or thapsigargin were $0.42{\pm}0.15$ and $0.49{\pm}0.07$, respectively (n=7), which are significantly reduced, compared to the control value of $0.72{\pm}0.07$ in a $Ca^{2+}$-free/2 mM EGTA solution. After the protonophore CCCP ($10{\mu}M$) challenge to release mitochondrial $Ca^{2+}$, the similar result was obtained. Ratio-difference before and after the application of DTBNP after pretreatment with CCCP was $0.46{\pm}0.09$ (n=7). Simultaneous application of thapsigargin and CCCP completely abolished the DTBNP-induced $[Ca^{2+}]_i$ increase. The above results together indicate that the increase of $[Ca^{2+}]_i$ by DTBNP resulted from the release of $Ca^{2+}$ from both endoplasmic reticulum and mitochondria.

• Journal of Korea Society of Digital Industry and Information Management
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• v.6 no.1
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• pp.33-54
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• 2010

Providing a secure 3-tier Web application has become a high priority for companies as e-businesses have increased the amount and the sensitivity of corporate information that can be accessed through the web. Web applications become more difficult to secure with this very increase in online traffic and transactions. This paper first reviews the 3-tier of web application, types of attacks that can threaten web application services and security principles. We then are designing and implementing a secure web application with open source software that able to mitigate the web application vulnerable to attack.

• International Journal of Advanced Culture Technology
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• v.10 no.1
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• pp.17-23
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• 2022

The purpose of this study is to develop a cancer rehabilitation program for cancer survivors in the form of a smartphone application and to confirm the effectiveness through Pilot study. The contents of the application consisted of health records, lab-test records, and health information, and the information recorded by the patient was graphically checked for changes over time on my page. 7 subjects who ended acute treatment and were undergoing follow-up were asked to use the application for 4 weeks, and then changes in variables (uncertainty, e-health literacy, self-efficacy, and cancer rehabilitation) were confirmed. It was confirmed that e-health literacy and self-efficiency increased significantly over time after using the application. In addition, the level of cancer rehabilitation was found to increase significantly over time. The application for cancer rehabilitation developed in this study needs to be expanded to improve the quality of life of cancer survivors.

• Applied Biological Chemistry
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• v.9
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• pp.149-152
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• 1968

In order to establish a effective application method of compost and phosphorus fertilizer for rice plant, a field experiment has been conducted and the variation of the organic matter content in soils has been observed. The results may be summarized as follows. 1. It was more effective to split the application time into basic and in 2 weeks before the young premodia formation for the yield increase of rice grain than to applicate once basic, and it was apparent that the lesser amount of organic matter during the growing period of rice was consumed, the higher yield of rice grain was resulted. 2. The combined application of compost and phosphorus fertilizer showed a tendency to raise higher the grain yield than the separated application. 3. It was suggested that the split application of compost bring yield increase of rice grain.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.209-209
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• 2017

The application of liquid swine manure to soil has been commonly reported to increase crop productivity by improving plant nutrient availability. This study was conducted to investigate the effect of liquid swine manure (LSM) application on yield of green manure crops in paddy. Three different application rates of LSM equivalent to 25%, 50%, and 75% of standard fertilization rate of P were applied to the paddy field after rice harvest, and two cover crops, hairy vetch (Vicia villosa Roth) and barley (Hordeum vulgare L.), were subsequently mix-seeded and cultivated. Plant height of barley was 7% higher in LSM P25% and LSM P50% compared to control treatment (no LSM application), while no significant difference was observed between LSM P75% and control. However, there were no significant differences in plant height of hairy vetch among treatments. Dry matter (DM) yield of green manure increased with LSM application rate, reaching a maximum at LSM P50% (38 and 17% yield increase over control for hairy vetch and barley, respectively), but it decreased at LSM P75% rate. Nitrogen production by green manure crops was the highest in LSM P50% treatment, where the amount of produced N was 57% higher than the optimum N fertilization level for rice ($90kg\;N\;ha^{-1}$). Excess green manure biomass above an optimum level can be removed and utilized either for incorporation into nearby cropland or for sale as fresh forage. Therefore, it is concluded that the application rate of LSM P50% is recommendable for the maximum biomass and nitrogen production from green manure crops in paddy.

• The Journal of Industrial Distribution & Business
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• v.10 no.10
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• pp.45-51
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• 2019

Purpose - The purpose of this study was to propose a win-win development plan for not only suppliers of delivery applications but also traditional market vendor companies and delivery riders by analyzing existing delivery models and presenting a new delivery model to enhance competitiveness of the traditional market using delivery apps. Research desgin, data, and methodology - Specifically, small retailers, such as traditional markets and supermarkets, presented a compromised delivery model that utilizes the platform of specialized delivery app service providers for order reception, and that the delivery is delivered by delivery systems jointly hired by Vendor companies, such as franchising companies. To validate the significance of the trade-off delivery model, a cost-benefit analysis was conducted by those involved in the delivery application. Results - From the perspective of suppliers of specialized delivery applications, it is analyzed that the use of specialized delivery applications in traditional markets will be a new market opportunity for service providers to achieve increased sales. It is expected that consumer choice and satisfaction will be increased as convenience and accessibility of traditional market businesses that were available only through direct visit from the user side of the delivery application will be expanded. From the standpoint of delivery application franchises, it is analyzed that they can seek to increase sales and increase customer service as well as ease labor cost burden due to joint employment of delivery riders. The delivery rider will be able to seek to improve customer service due to job security, wage stability, risk reduction and overheated competition due to direct employment. Conclusion - In conclusion, the compromised delivery model solved the problems raised in the preceding study conducted on delivery application suppliers, users, franchises, and riders to establish that it could be a strategic alternative to increasing sales and expanding detailed rights for the self-employed in the traditional market, which are experiencing difficulties in management. However, the adoption of a compromise delivery model requires social consensus from those involved in the delivery application and requires legal, institutional and policy support, which will require continued follow-up research on the delivery model in the future.

• The KIPS Transactions:PartA
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• v.13A no.4 s.101
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• pp.275-288
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• 2006

Rapid design space exploration is crucial to customizing embedded system design for exploiting the application behavior. As the time-to-market becomes a key concern of the design, the approach based on an application specific instruction-set processor (ASIP) is considered more seriously as one alternative design methodology. In this approach, the instruction set architecture (ISA) for a target processor is frequently modified to best fit the application with regard to code size and speed. Two goals of this paper is to introduce our new retargetable compiler and how it has been used in ASIP-based design space exploration for a popular digital signal processing (DSP) application. Newly developed retargetable compiler provides not only the functionality of previous retargetable compilers but also visualizes the features of the application program and profiles it so that it can help architecture designers and application programmers to insert new application specific instructions into target architecture for performance increase. Given an initial RISC-style ISA for the target processor, we characterized the application code and incrementally updated the ISA with more application specific instructions to give the compiler a better chance to optimize assembly code for the application. We get 32% performance increase and 20% program size reduction using 6 audio codec specific instructions from retargetable compiler. Our experimental results manifest a glimpse of evidence that a higgly retargetable compiler is essential to rapidly prototype a new ASIP for a specific application.

• Korean Journal of Soil Science and Fertilizer
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• v.26 no.2
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• pp.78-84
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• 1993

In order to know the effect of sludge from water treatment plants un agricultural environment, an experiment of water treatment sludge application for Altari radish (Raphanus sativus L.) was carried out. And the results were as follows ; 1. The pH of water treatment sludge was 7.2, which was higher than that of the experimental soil. The exchangeable Ca content in the sludge was very high being 29me/100g sludge. So when the sludge was applied to the soil, amending effect for soil acidity was supposed. 2. With the application of the water treatment sludge to the soil, soil pH and organic matter content were increased. With the increase of the level of sludge application, contents of crude fiber and Ca in Altari radish were increased, white those of P and Mg tended to decrease. 3. The length of the root and the amount of fresh yield of the whole plant of radish tended to increase with the increase of sludge application, and this tendency was more evident on the infertile soil. From the above results, it was concluded that the fresh yield of Altari radish increased up to 75ton/ha sludge application on the fertile soil, but the yield decreased when higher levels of sludge was applied. While on the infertile soil, the yield increased up to the application of 300ton/ha, and the heavier application level did not adversely affect the yield of Altari radish.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.21 no.2
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• pp.222-232
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• 1976

Two different cultivars of barley, with either the ordinary-level or double-strength nitrogen application, were grown in two districts simultaneously, in order to study the extent of dwarfing in plant height, lodging and grain-yield increase with ethylene-releasing agents (Ethrel and dl-methionine alone or in combination). The shorter the plant height, the less the extent of lodging and the grain yield there were. With 500ppm Ethrel, 10% grain-yield increase was attained without showing apparent lodging, irrespective of the level of nitrogen applied. The double-strength nitrogen application resulted in severe lodging more than the ordinary-level and control, and lower grain yield accordingly. Consideration for importance of barley lodging in Korea today and the controlling measure with ethylene treatment for dwarfing, and yield increase by increased nitrogen application, were discussed.

• Korean Journal of Medicinal Crop Science
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• v.23 no.2
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• pp.150-154
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• 2015

Physiological disorders such as symptoms in leaf colored with brown spots are so many occurred in ginseng garden cultivated with paddy soil. This study was carried out to inhibit the symptoms of brown-colored leaf in 3-year-old ginseng by fertilizing calcium hydroxide [$Ca(OH)_2$] of 100 ~ 400 kg per 10a on paddy soil before transplant of seedling. Soil pH was rapidly increased, while Fe was decreased in soil by the increase of application level of calcium hydroxide. Soil pH was increased from 4.53 to 6.18 when calcium hydroxide was fertilized at level of 100kg per 10a. The content of Fe in ginseng leaf was decreased more than the control by fertilizing calcium hydroxide in soil. Ratio of brown-colored leaf and plant height and leaf area were decreased by the increase of calcium hydroxide. Ratio of survived root and yield of root showed the peak at the application level of 100 kg per 10a, and both of them were gradually decreased by the increase of calcium hydroxide. The decrease of missing plant rate above the application level of 200 kg per 10a had a negative effect on the decrease of yield of root.