• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제26권3호
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• pp.7-16
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• 2020

Purpose: As communicable disease, COVID-19, pandemic strikes over the world, it is critically bewared that air travel possibly be a major pass way to deliver the infectious disease virus. Especially the airplane could be an unique environment to cultivate the virus spreaders. In order to keep the continuous safe airway as well as the industry, related international associations and organizations have been published the guidelines for the prevention and control the infectious disease through the all aspects of aviation. By reviewing the guidelines, focusing on the in-flight infection prevention and control, this study would not only inform a summary of the international guidelines but also provide an essential and general consideration for related research or guideline study. Methods: Guidelines of 5 major countries are reviewed, which has been seriously influenced by COVID-19 : U.S., Canada, E.U., Australia and China. The items of the guidelines are re-categorized as its similarity and structure by applicable cases. Results: The result of this study shows that each guideline seems to share a major structure and issue such as identifying sick traveler, sick passenger care, and cleaning even though that of China has a different since it used to consider the flight conditions based on 3 levels of infection risk. For sick passenger care, the guidelines includes crew safety, service level, sick passenger isolation, and cleaning. Implications: A published guideline as a public manual could be to prevent and control the in-flight infection efficiently and promptly. It also could provide a confidence of knowledge and educate for all users to prepare the in-flight emergency as well.

• 항공우주의학회지
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• 제30권3호
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• pp.91-94
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• 2020

The coronavirus infectious disease-19 (COVID-19) pandemic has had a profound impact on the aviation industry. In order to overcome this crisis, airlines have made their efforts in various fields. Therefore, we tried to summarize these efforts of airlines. It is also essential to keep aircraft that have been in landing for a long time in optimal condition. In this paper, we tried to find out about efforts to maintain landing aircraft and maintenance of personnel. Through such constant care, airlines will be able to quickly respond to increasing aviation demand when the infectious disease situation is stabilized in the future. Finally, airlines and passengers must make several efforts to ensure that passengers are free from COVID-19 while traveling by air. These include general precautions to prevent infection, separation of airline personnel and passengers, changes in seat assignments and in-flight services, periodic aircraft disinfection, and prevention of in-flight infections.

• Asian Pacific Journal of Cancer Prevention
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• 제14권1호
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• pp.367-372
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• 2013

Effects of the Epstein-Barr virus (EBV) on cellular protein expression are essential for viral pathogenesis. To characterize the cellular response to EBV infection, differential proteomes of gastric epithelial AGS cells were analyzed with two-dimensional gel electrophoresis (2-DE) followed by matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) and liquid chromatography electrospray/ionization ion trap (LC-ESI-IT) mass spectrometry identification. Mass spectrometry identified 9 altered cellular proteins, including 5 up-regulated and 4 down-regulated proteins after EBV infection. Notably 2-DE analysis revealed that EBV infection induced increased expression of heat shock cognate 71 kDa protein, actin cytoplasmic 1, pyridoxine-5'-phosphate oxidase, caspase 9, and t-complex protein 1 subunit alpha. In addition, EBV infection considerably suppressed those cellular proteins of zinc finger protein 2, cyclin-dependent kinase 2, macrophage-capping protein, and growth/differentiation factor 11. Furthermore, the differential expressional levels of partial proteins (cyclin-dependent kinase 2 and caspase 9) were confirmed by Western blot analysis.Thus, this work effectively provided useful protein-related information to facilitate further investigation of the mechanisms underlying EBV infection and pathogenesis.

• 한국항공운항학회지
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• 제30권3호
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• pp.65-75
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• 2022

This study tried to confirm whether the public's negative emotions such as fear and anxiety about corona virus infection caused by the spatial nature of the aircraft were alleviated due to factors of in-flight services focusing on hygiene and quarantine and further had a positive effect on the formation of Rapport between cabin crews and passengers. We also investigated the impact on passengers' perceptions such as Reliability and Safety which can be viewed as a new measure and standard of customer satisfaction in the Pandemic era through Rapport. A survey was conducted online in December 2021 for passengers with experience in boarding aircraft after the COVID-19 outbreak, and a total of 211 responses were used for analysis. As a result of the analysis of the data, it was confirmed that aircraft in-flight service had a positive (+) effect on Rapport, and Rapport between passengers and cabin crews had a positive (+) effect on passenger Reliability and Safety.

• 한국항공운항학회지
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• 제31권1호
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• pp.43-56
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• 2023

The aviation industry has continued to grow despite the influence of external environmental factors such as SARS and MERS. However, this growth has led to a sharp decrease in air traffic and a crisis of flight suspension due to the collapse of the global value chain and the decline of the world economy as the World Health Organization (WHO) declared a COVID-19 pandemic. Due to the decrease in the number of international flights, aviation workers such as pilots and cabin crew were exposed to high psychological stress and fatigue, such as large-scale layoffs, job instability, decrease in income, and increased risk of infection during. Recently, the international community has eased immigration restrictions through quarantine activities, and airlines are taking a step further to recover existing air demand. However, during the crisis period, a significant number of professional workers have been turned off or fired, and the physical and mental fatigue of those who can perform their duties is increasing. Therefore, this paper intends to examine the direction of policy improvement and the identification of problems in aviation safety and fatigue management after the pandemic.

• 한국동물위생학회지
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• 제35권1호
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• pp.39-45
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• 2012

This survey aims to provide information on the pattern of distress in wild avian animals in Gangwon province. This survey is based on 315 wild avian which were rescued by the Kangwon University Wildlife Rescue Center. The data was collected at the Wildlife Animal Center from September 2007 to August 2010, and by analyzing the shape of the wild animals killed or injured, the center seeks an efficient and systematic way to manage such distress. There are 55 species found, in this study including 40 common kestrel, 34 eurasian eagles, 20 common buzzards, 20 collared scops owls, 19 oriental scops owls, 16 brown hawk owls and 160 others. These are the results of the survey: 129 (40.3%) of 315 avian birds were found between June and August. Many cases in that term were observed falling from the nest or losing their mother because of unskilled flight during the breeding season's flight practicing process. Between November and December, 64 individual (20.3%) were found, and it's the second largest number. The main reasons for these results were starvation and exhaustion from the winter migratory season. The results indicated that the main reason for avian distress came from the following: collision with architecture windows in 73 cases (23.2%), starvation and exhaustion in 63 cases (20.0%), collision with vehicles in 51 cases (16.2%), becoming orphaned in 69 cases (21.9%), trespassing into buildings occurred in 19 cases (6.0%), collision with electric wires in 18 cases (5.7%), poaching materials in 13 cases (4.1%), becoming entangled by fishing wire and other miscellaneous materials in 4 cases (1.3%), infection from parasites in 4 cases (1.3%), toxicosis from such toxins like agricultural chemicals in 1 case (0.3%). Overall, the purpose of this investigation was to analyze cases of avian distress in Korea's wildlife. This study used areas, seasons and causes to understand origins of these animals distress. So that it can be utilized for organized wild avian rescue and treatment.

• Clinical and Experimental Pediatrics
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• 제61권6호
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• pp.200-204
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• 2018

Atopic dermatitis (AD) is a chronic inflammatory skin disease in children. Patients with AD experience a high rate of colonization of the skin surface by Staphylococcus aureus. Because of a skin barrier defect, there is a potential risk of staphylococcal invasive infection in patients with AD. Here, we present 2 cases of breast abscess caused by S. aureus in 2 adolescent girls with severe AD. Methicillin-sensitive S. aureus was identified from the breast abscess material. They were treated with appropriate antibiotics, however surgical drainage of the abscess was needed in case 1. Identical strains were found from the breast abscess material as well as the lesional and the nonlesional skin of the patients through matrix-assisted laser desorption/ionization time-of-flight analysis. We characterized the differential abundance of Firmicutes phylum in patients' skin in microbiota analysis. In particular, S. aureus, a member of Firmicutes, differed significantly between the lesional and the normal-appearing skin. Our cases demonstrate the potential severity of bacterial deep tissue infection in AD and the dysbiosis of skin microbiota may be involved in inflammation in AD.

• 한국임상수의학회지
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• 제40권6호
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• pp.393-398
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• 2023

We identified mastitis-causing pathogens using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) in an organic dairy farm and evaluated the effects of antimicrobial restriction on antimicrobial susceptibility. A total of 43 Holstein cows without any clinical sign of mastitis were used in this study, and 172 quarter milk samples were cultured on blood agar plates for 24 hours at 37℃. Subsequently, bacterial species were identified and antimicrobial susceptibility tests were performed. The subclinical mastitis infection rates in the cows and quarters were 58.1% (25/43) and 25.6% (44/172), respectively. In the species identification, Staphylococcus aureus (40.9%) was the most prominent isolate, followed by S. chromogenes (22.7%), S. epidermis (18.2%), S. simulans (11.4%), S. haemolyticus (2.3%), S. muscae (2.3%), and S. xylosus (2.3%). In the antimicrobial susceptibility test, all isolates were 100% susceptible to 24 of 28 antibiotics, except for benzylpenicillin, cefalotin, cefpodoxime, and trimethoprim/sulfamethoxazole. The resistance rates of S. aureus, S. chromogenes, and S. muscae isolates to trimethoprim/sulfamethoxazole were 27.8%, 10%, and 100%, respectively, and the resistance rates of S. epidermis and S. xylosus to benzylpenicillin were 50% and 100%, respectively. S. chromogenes, S. epidermis, S. simulans, S. haemolyticus, and S. xylosus were resistant to cefalotin and cefpodoxime. In conclusion, restrictions on antimicrobial use for organic dairy farm certification have resulted in a high Staphylococcus spp. infection rate. Therefore, our study indicates the importance of mastitis management strategies implemented by farmers together with veterinary practitioners, even if mastitis does not appear clinically in organic dairy farms.

• 대한임상검사과학회지
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• 제52권1호
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• pp.18-27
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• 2020

카바페넴내성장내세균속균종(carbapenem-resistant Enterobacteriaceae, CRE)과 카바페넴분해효소 생성 장내세균과(carbapenemase-producing Enterobacteriaceae, CPE)의 정확한 구분과 CPE의 빠른 탐지는 임상 감염의 치료 및 관리에 중요하다. 선별방법은 주로 선택적 배지에서의 직장 면봉 표본 배양 후 카바페넴분해 효소의 활성도, 신속한 카바페넴의 불활성화 방법, 측방유동면역분석(lateral flow immunoassay, LFI), 메트릭스보조레이저 탈착/이온화이온사이클론 공명 질량분석법(matrix assisted laser desorption/ionisation time of flight mass spectrometry, MALDI-TOF MS)을 통해 표현형을 측정하는 분자기반 방법들이다. CRE, 특히 CPE의 적절한 시기에 정확한 탐지는 감염의 임상 치료 및 예방에 필수적이다. 다양한 표현형 검출방법 및 유전자-기반 검출방법이 카바페넴의 신속한 검출을 위해 이용 가능하며, 이들은 임상 미생물학 실험실에서 일상적으로 사용된다. 신속한 처리 시간으로 현장에서 치료를 위한 검사 방법을 사용하는 CRE에 대한 능동적인 감시활동에서 카바페넴분해효소를 생성하는 CRE의 탐지는 중요한 가치를 갖는다. 따라서 카바페넴분해효소의 확산을 통제하기 위해서는 전세계의 많은 검사실에서 신뢰할 수 있고 신속하고 고효율적이며, 간편하고 저비용의 검사법을 사용해야 할 것이다. 환자의 적용에서도 최적의 효과를 가지려면 CRE에 대한 신속한 검사를 통해 항균제의 관리 개입이나 다양한 형태의 임상 의사의 치료에 결정적인 지원을 재현성있게 나타나야 할 것이다. 최적의 검사법을 위해서는 보완되는 검사법을 결합하여 다양한 내성 박테리아 종을 감별하고 다양한 종류의 카바페넴분해효소의 유전적 다양성을 발굴하여 최상의 감염관리 전략을 포괄하는 시스템이 마련되어야 할 것으로 사료된다.

• 항공우주의학회지
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• 제31권3호
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• pp.64-67
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• 2021

When the COVID-19 crisis hit air transport, the whole aviation industry was affected. The change in the behavior of passengers following the COVID-19 crisis, travel restrictions and the ensuing economic crisis have resulted in a dramatic drop in demand for airline services. The COVID-19 pandemic, with all its associated consequences, has had a significant impact on the mental health and well-being of pilots, which could impact operational safety. As the number of international flights has decreased, pilots are exposed to high levels of psychological stress such as job instability, reduced income and increased risk of infection during flight work. Psychological stress lowers work performance and threatens aviation safety. The pilot needs mental health management during the COVID-19 pandemic, but psychological support is weak. For pilot mental health management, it is important to raise awareness about mental health and to continuously respond. To this end, it is necessary to foster a safe and trustworthy culture in which mental health issues are discussed freely and solved together without hiding them. They should also support the establishment of a peer support program that is easily accessible and that allows pilots to discuss their issues with confidence.