• Title/Summary/Keyword: impulses

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A Causal Analysis of Suicidal Impulse in the Context of Parents, Friends, Teachers and Community Support: Gender Difference (부모, 친구, 교사, 지역사회 지지와 청소년의 자살충동간 인과관계 분석 : 성별 차이를 중심으로)

  • Kim, Hyun-Ju;Roh, Ja-Eun
    • Korea journal of population studies
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    • v.34 no.2
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    • pp.135-162
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    • 2011
  • Given the 4 contexts-parents, friends, teachers and community- of adolescents, this research verified the casual relationships between each contextual support and the suicidal impulse, and the gender difference. The 4-year longitudinal data(KYPS) collected from 3,697 adolescents were used in this study. Using the Autoregressive Cross-Lagged Model, the suicidal impulse was consistently present from the 3rd grade in middle school to the 3rd grade in high school with significant stability. Gender differences were founded in the effect of parental support among the 3rd grade in middle school. Also the negative effect of friends' support on the suicidal impulse among the first grade high school students. The effects were more stronger for girls than boys. Previous supports by teachers and community had no significant effects on later suicidal impulses. These results suggest that the study of suicidal impulse needs to examine the complex support system of multiple context layers.

Promotion of Remyelination by Sulfasalazine in a Transgenic Zebrafish Model of Demyelination

  • Kim, Suhyun;Lee, Yun-Il;Chang, Ki-Young;Lee, Dong-Won;Cho, Sung Chun;Ha, Young Wan;Na, Ji Eun;Rhyu, Im Joo;Park, Sang Chul;Park, Hae-Chul
    • Molecules and Cells
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    • v.38 no.11
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    • pp.1013-1021
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    • 2015
  • Most of the axons in the vertebrate nervous system are surrounded by a lipid-rich membrane called myelin, which promotes rapid conduction of nerve impulses and protects the axon from being damaged. Multiple sclerosis (MS) is a chronic demyelinating disease of the CNS characterized by infiltration of immune cells and progressive damage to myelin and axons. One potential way to treat MS is to enhance the endogenous remyelination process, but at present there are no available treatments to promote remyelination in patients with demyelinating diseases. Sulfasalazine is an anti-inflammatory and immune-modulating drug that is used in rheumatology and inflammatory bowel disease. Its anti-inflammatory and immunomodulatory properties prompted us to test the ability of sulfasalazine to promote remyelination. In this study, we found that sulfasalazine promotes remyelination in the CNS of a transgenic zebrafish model of NTR/MTZ-induced demyelination. We also found that sulfasalazine treatment reduced the number of macrophages/microglia in the CNS of demyelinated zebrafish larvae, suggesting that the acceleration of remyelination is mediated by the immunomodulatory function of sulfasalazine. Our data suggest that temporal modulation of the immune response by sulfasalazine can be used to overcome MS by enhancing myelin repair and remyelination in the CNS.

Gait Asymmetry in Children with Down Syndrome (다운증후군 아동들의 보행 비대칭성 연구)

  • Lim, Bee-Oh;Han, Dong-Ki;Seo, Jung-Suk;Eun, Seon-Deok;Kwon, Young-Hoo
    • Korean Journal of Applied Biomechanics
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    • v.16 no.2
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    • pp.145-151
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    • 2006
  • A large interindividual variability and some abnormally kinematic patterns at the lower extremity were the main features of the gait in children with Down syndrome. The purposes of this study were to investigate the gait asymmetry and biomechanical difference between dominant leg and non dominant leg in children with Down syndrome. Seven boys with Down Syndrome(age: $120{\pm}0.9yrs$, weight $34.4{\pm}8.4kg$, leg length: $68.7{\pm}5.0cm$) participated in this study. A 10.0 m ${\times}$ 1.3 m walkway with a firm dark surface was built and used for data collection. Three-dimensional motion analyses were performed to obtain the joint angles and range of motions. The vertical ground reaction forces(%BW) and impulses($%BW{\cdot}s$) were measured by two force plates embedded in the walkway. Asymmetry indices between the legs were computed for all variables. After decision the dominant leg and the non dominant leg with max hip abduction angle, paired samples t-test was employed for selected kinematic and ground reaction force variables to analyze the differences between the dominant leg and the non dominant leg. The max hip abduction angle during the swing phase showed most asymmetry, while the knee flexion angle at initial contact showed most symmetry in walking and running. The dominant leg showed more excessive abduction of hip in the swing phase and more flat-footed contact than the non dominant leg. Vertical peak force in running showed more larger than those of in walking, however, vertical impulse showed more small than walking due to decrease of support time. In conclusion, the foot of dominant leg contact more carefully than those of non dominant leg. And also, there are no significant difference between the dominant leg and the non dominant leg in kinematic variables and ground reaction force due to large interindividual variability.

Experimental Study on Friction Characteristics between Sliding Polymer Plates for Reduction of Stick-and-Slip Abnormal Noise (스틱-슬립음 발생저감을 위한 고분자 소재간 실험적 미끄럼 마찰특성 분석)

  • Lee, Dong-Gyu;Park, Hee-Jin;Park, Sang-Hu
    • Polymer(Korea)
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    • v.37 no.5
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    • pp.642-648
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    • 2013
  • There is a kind of abnormal noise known to come from the stick-slip mechanism induced by frictional impulses during the sliding of two polymeric plates. In this work, quantitative analysis of abnormal noise is carried out based on experimental results. Some combinations of polymer plates, such as an ABS base-plate contacted to ABS, PP, MIPS, and POM plates, which are well-known materials used in home-appliances, are studied to obtain the best combination of polymer plates in order to reduce the abnormal noise. For the experiments, a rig for the test was set up and a methodology was proposed. In addition, the effects of the surface roughness of the plate, the normal loading force, and the relative sliding speed between the two contact plates were evaluated in order to understand the reason for the abnormal noise. Through this experimental work, the optimal combination of materials was ABS/POM system to reduce the noise in real industrial applications.

Wet Drop Impact Response Analysis of CCS in Membrane Type LNG Carriers -I : Development of Numerical Simulation Analysis Technique through Validation- (멤브레인형 LNG선 화물창 단열시스템의 수면낙하 내충격 응답해석 -I : 검증을 통한 수치해석 기법 개발-)

  • Lee, Sang-Gab;Hwang, Jeong-Oh;Kim, Wha-Soo
    • Journal of the Society of Naval Architects of Korea
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    • v.45 no.6
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    • pp.726-734
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    • 2008
  • While the structural safety assessment of Cargo Containment System(CCS) in membrane type LNG carriers has to be carried out in consideration of sloshing impact pressure, it is very difficult to figure out its dynamic response behaviors due to its very complex structural arrangements/materials and complicated phenomena of sloshing impact loading. For the development of its original technique, it is necessary to understand the characteristics of dynamic response behavior of CCS structure under sloshing impact pressure. In this study, for the exact understanding of dynamic response behavior of CCS structure in membrane Mark III type LNG carriers under sloshing impact pressure, its wet drop impact response analyses were carried out by using Fluid-Structure Interaction(FSI) analysis technique of LS-DYNA code, and were also validated through a series of wet drop experiments for the enhancement of more accurate shock response analysis technique. It might be thought that the structural response behaviors of impact response analysis, such as impact pressure impulses and resulted strain time histories, generally showed very good agreement with experimental ones with very appropriate use of FSI analysis technique of LS-DYNA code, finite element modeling and material properties of CCS structure, finite element modeling and equation of state(EOS) of fluid domain.

Spin Wave Interference in Magnetic Nanostructures

  • Yang, Hyun-Soo;Kwon, Jae-Hyun;Mukherjee, Sankha Subhra;Jamali, Mahdi;Hayashi, Masamitsu
    • Proceedings of the Korean Magnestics Society Conference
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    • 2011.12a
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    • pp.7-8
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    • 2011
  • Although yttrium iron garnet (YIG) has provided a great vehicle for the study of spin waves in the past, associated difficulties in film deposition and device fabrication using YIG had limited the applicability of spin waves to practical devices. However, microfabrication techniques have made it possible to characterize both the resonant as well as the travelling characteristics of spin waves in permalloy (Py). A variety of methods have been used for measuring spin waves, including Brillouin light scattering (BLS), magneto-optic Kerr effect (MOKE), vector network analyzer ferromagnetic resonance (VNA-FMR), and pulse inductive microwave magnetometry (PIMM). PIMM is one of the most preferred methodologies of measuring travelling spin waves. In this method, an electrical impulse is applied at one of two coplanar waveguides patterned on top of oxide-insulated Py, producing a local disturbance in the magnetization of the Py. The resulting disturbance travels down the Py in the form of waves, and is inductively picked up by the other coplanar waveguide. We investigate the effect of the pulse width of excitation pulses on the generated spin wave packets using both experimental results and micromagnetic simulations. We show that spin wave packets generated from electrical pulses are a superposition of two separate spin wave packets, one generated from the rising edge and the other from the falling edge, which interfere either constructively or destructively with one another, depending upon the magnitude and direction of the field bias conditions. A method of spin wave amplitude modulation is also presented by the linear superposition of spin waves. We use interfering spin waves resulting from two closely spaced voltage impulses for the modulation of the magnitude of the resultant spin wave packets.

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Quantitative assessment of reclamation-dams from the sea by using combined seismic methods (해안 매립지 탄성파 탐사)

  • Kim Jung-Yul
    • 한국지구물리탐사학회:학술대회논문집
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    • 2002.09a
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    • pp.85-100
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    • 2002
  • This paper deals with a development of combined seismic methods, based on the application of Televiewer and seismic tomography, for the quantitative assessment of reclaimed body or dam at seashores in our county. The underground structure of reclaimed dam is very complex, mainly due to the unexpected exchange of rock fragments with the marine silty mud in conjunction with S.C.P. (Sand Compaction Pile) foundation, so that for several reasons only the use of Televiewer and seismic tomography for general application might not lead to a desirable resolution. Kinds of upgraded measuring and evaluation techniques for that are needed. For examples, a novel strategy for capturing the returning impulses from the outer side of casing plastic pipe is desired to be developed. For the tomograhy, one should be being more focussed on the study of raw data based on the wave propagation theory. In this paper, it is shown that such multidisciplinary approaches can be, by attempting to compare and jointly interpret the results from two methods, much efficient for understanding the reclaimed dam structure.

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A Study on the Relationship between Mother's Child-rearing Practices and Children's Critical Thinking Abilities (어머니의 육아방식과 아동의 비판적 사고력과의 관계에 관한 연구)

  • 안순자
    • Journal of the Korean Home Economics Association
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    • v.20 no.4
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    • pp.193-204
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    • 1982
  • This study attempts to clarify the relationship between mother;s child-rearing practices and children's critical thinking abilities. More specifically this study wants to answer the questions: (a) Is there any relationship between mother's child-rearing practices and children's critical thinking abilities? (b) What dimensions of child-rearing practices are more important for children's critical thinking abilities? (c) Does the developmental process of children's critical thinking abilities show any difference according to the mother's child-rearing practices? This study is based on the conceptual model of child-rearing practices from the cognitive disciplinary viewpoint proposed by Lee et al.(1973). They polarized the child-rearing practices into the“mediated”types. These types were specified along seven dimensions of child-rearing. In general terms, the two types refer to the degree to which mother resorts to the description of concrete and immediate phenomena and immediate expression of momentary impulses, and positively reinforces such behaviors of her children. Two kinds of data were collected from 60 primary school boys and girls, and their mothers. A child-rearing practices questionnaire with 28 items was sent to the mothers. And the children were administered a critical thinking abilities test containing measures of 4 dimensions from the Ahn's Critical Thinking Measurement Technique. The major findings are those (a) the children of mothers who reported to have used more“mediated”types of child-rearing show relatively higher level of critical thinking abilities than their counterparts; (b) of the seven dimensions of child-rearing practices, the most significant are“mode of description”,“rationality-orientation”and“reward and punishment”; and (c) the“mediated”type of child-rearing practices tends to facilitate critical thinking abilities development. In conclusion, it is believed that a further refinement of this study will contribute to the development of child-rearing training program for mothers.

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CHANGES IN INTRADENTAL NERVE ACTIVITY FOLLOWING LOCAL APPLICATION OF CGRP, SP AND ELECTRICAL STIMULI IN CATS (CGRP, SP의 국소도포와 전기자국에 의한 고양이 치수신경활동의 변화)

  • Kim, Mi-Ja;Son, Ho-Hyun
    • Restorative Dentistry and Endodontics
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    • v.20 no.2
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    • pp.527-537
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    • 1995
  • The effect of calcitonin gene-related peptide (CGRP), substance P (SP) and electrical stimulation of the tooth on the intradental nerve activtiy (INA) was investigated in anesthetized cats. The INA was recorded from single pulp nerve units dissected from the inferior alveolar nerve under stereomicroscope. The INA elicited by 3 minute application of 4M NaCl in deep dentinal cavity was compared before and after stimulation at 10 minute intervals. The magnitude of INA was calculated as the total number of nerve impulses produced in given period, and the changes of INA are expressed as % of control INA. The results obtained were as follows. 1. 16 single pulp nerve units were classified as 14 $A{\delta}$-fibers (3.4~19.4m/sec) and 2-fibers (1.5~1.7m/sec) according to the conduction velocity. 2. 4M NaCl evoked an irregular bursts of spikes which continued until washing out. Isotonic saline did not affect INA to subsequent applications of the hypertonic NaCl solution (P>0.05). 3. Local application of CGRP ($200{\mu}g$/ml) in deep dentinal cavity reduced the INA induced by 4M NaCl in $A{\delta}$-fiber units (P<0.01) and some units of those responded to CGRP during application. 4. Local application of SP ($100{\mu}g$/ml) in deep dentinal cavity reduced the INA induced by 4M NaCl in AS-fiber units (p<0.05), but increased the INA in C-fiber unit coincided with large reduction of the INA of $A{\delta}$-fiber units. 5. Monopolar electrical stimulation applied to the crown at intensities high enough to excite C-fibers (12V, 5ms, 10Hz, 10~30min) decreased the INA in $A{\delta}$-fiber units (P<0.01) and systemic pretreatment with phenoxybenzamine (3mg/kg, i.v.) enhanced this inhibitory effect (P<0.01). On the contrary, electrical stimulation increased the INA in C-fiber unit.

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Public Participation in Healthcare Decision Making : Experience of Citizen Council for Health Insurance (보건의료 정책 의사결정과 시민참여 : 『건강보험 보장성 시민위원회』의 사례)

  • Kwon, Soonman;You, Myoungsoon;Oh, Juhwan;Kim, Soojung;Jeon, Boyoung
    • Health Policy and Management
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    • v.22 no.4
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    • pp.467-496
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    • 2012
  • Public participation in the decision making for scarce health resources is important because health policy requires trust based consensus, which can be achieved by public's understanding and involvement of related policies. In the past, opportunities for interaction between health policy decision makers and lay public were rare in Korea. As political impulses towards public participation in health policy have increased, a few of deliberation methods were attempted. However, there is little research, reporting such cases with a critical examination of relevant theories and previous studies. We first critically review the literature on public participation within theories of democracy, governance, and empowerment. Next, we report a case of a citizen council experiment, which was held to examine public's preferences among different benefit options regarding new drugs and medical technologies. Specifically, in an one-day long citizen council with a total of 28 lay public, twelve questions of whether a drug or a technology should be included in the benefit package of health insurance were asked. Pre- and post-surveys investigated participants' perception of public engagement in health policy. Although it was experimental, the citizen council ensured that lay public could be careful enough to rationally compare the costs and benefits of different options and collectively make decisions. Further, results from pre- and post-survey showed a strong willingness of members to be involved in health care decision making. In the conclusion, we emphasize that better theories and methods need to be developed for more cases of citizen participation in health care policy and management.