• 제목/요약/키워드: improved effects

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죽엽석고탕가감방(竹葉石膏湯加減方)이 항암화학요법제(抗癌化學療法劑)의 세포독성(細胞毒性)과 종양세포(腫瘍細胞)의 성장억제(成長抑制)에 미치는 효과(效果)에 대한 연구 (Effects of Jukyeopseokgotanggagambang on Anti-tumor Chemotherapeutic Cytotoxicity and Lysosomal Enzymes of Tumor Cell)

  • 전승훈;문구;전병훈
    • 대한한방내과학회지
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    • 제18권1호
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    • pp.191-206
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    • 1997
  • In order to investingate the effects of Jukyeopseokgotanggagambang Extract on antitumor effects after human cell lines(A549, hep3B, Caki-1, Ehrlich) transplantation into the peritoneal cavity or right groin in mice induced by RPMI 1640 and GIBCO etc., the extracts of its herbal medicines were orally administered for 10 or 12days. Experimental studies were performed for measurance of antitumor effect of MMC(Mitomycin C) and lysosomal enzyme's activities using colony forming efficiency, SRB assay which were regarded as a valuable method for antitumor effects of unknown compound on tumor cell lines. The results obtained in this studies were as follows: 1. According to the change of colony-forming efficiency and SRB assay of Caki-1 cell, hep3B and A549 cells after exposure to the extract of Jukyeopseokgotanggagambang extract, that extract depressed the growth of tumor cells depending on its concentration. 2. Antitumor activities of the ethanol extract from Jukyeopseokgotanggagambang extract and MMC on ascites form of Ehrlich carcinoma in mice is a little improved. Especially mean survival times of the group of Jukyeopseokgotanggagambang extract 200mg/kg and MMC 0.1mg/kg is improved over 30%. 3. When Jukyeopseokgotanggagambang extract and MMC are administerated together, the weight of tumor is more decreased than MMC alone. 4. The effects of the Jukyeopseokgotanggagambang extract and MMC on the lysosomal enzymes in Ehrlich ascites carcinoma cell are more significantly improved than MMC alone. 5. Jukyeopseokgotanggagambang extract also increased the uptake of MMC into Ehrlich carcinoma cells. According to the above results, it could be suggested that Jukyeopseokgotanggagambang extract has indirect autitumor effects by strengthening the effects of MMC on tumor cells.

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죽엽석고탕가감방(竹葉石膏湯加減方)이 항암화학요법제(抗癌化學療法劑)의 세포독성(細胞毒性)과 종양세포(腫瘍細胞)의 라이소솜에 미치는 영향(影響) (Effects of Jukyeopseokgotanggagambang on Anti-tumor Chemotherapeutic Cytotoxicity and Lysosomal Enzymes of Tumor Cell)

  • 전승훈;전병훈;원진희;문구;문석재
    • 대한한방종양학회지
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    • 제3권1호
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    • pp.149-167
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    • 1997
  • In order to investingate the effects of Jukyeopseokgotanggagambang Extract on antitumor effects after human cell lines(A549, hep3B, Caki-1, Ehrlich) transplantation into the peritoneal cavity or right groin in mice induced by RPMI 1640 and GIBCO etc., the extracts of its herbal medicines were orally administered for 10 or 12days. Experimental studies were performed for measurance of antitumor effect of MMC(Mitomycin C) and lysosomal enzyme's activities using colony forming efficiency, SRB assay which were regarded as a valuable method for antitumor effects of unknown compound on tumor cell lines. The results obtained in this studies were as follows: 1. According to the change of colony-forming efficiency and SRB assay of Caki-1 cell, hep3B and A549 cells after exposure to the extract of Jukyeopseokgotanggagambang extract, that extract depressed the growth of tumor cells depending on its concentration. 2. Antitumor activities of the ethanol extract from Jukyeopseokgotanggagambang extract and MMC on ascites form of Ehrlich carcinoma in mice is a little improved. Especially mean survival times of the group of Jukyeopseokgotang-gagambang extract 200mg/kg and MMC 0.1mg/kg is improved over 30%. 3. When Jukyeopseokgotanggagambang extract and MMC are administerated together, the weight of tumor is more decreased than MMC alone. 4. The effects of the Jukyeopseokgotanggagambang extract and MMC on the lysosomal enzymes in Ehrlich ascites carcinoma cell are more significantly improved than MMC alone. 5. Jukyeopseokgotanggagambang extract also increased the uptake of MMC into Ehrlich carcinoma cells. According to the above results. it could be suggested that Jukyeopseokgotanggagambang extract has indirect autitumor effects by strengthening the effects of MMC on tumor cells.

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초지형과 파종상 정지방법이 유거수량 , 토양 유실량 , 목초의 식생구성 , 건물수량 및 경제성에 미치는 영향 (Effects of the Pasture Types and the Leveling Methods of Seedbed on the Runoff , Soil Loss , Botanical Composition , Dry Matter Yield of Forage and Economical value)

  • 이종경;임영철;윤세형;김맹중;박근제;양종성;최선식;이성철
    • 한국초지조사료학회지
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    • 제18권1호
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    • pp.55-60
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    • 1998
  • This study was conducted to investigate the effects of the pasture types and the leveling methods of winding slope land for seedbed on the runoff, soil loss, botanical composition, dry matter yield of forage and economical value at the Experimental Field of Grassland and Forage Crops Division, National Livestock Research Institute, Suweon, from 1994 to 1995. The results obtained are summarized as follows: 1. Runoff of the improved land was higher than that of the unimproved land in the top grass and bottom grass. 2. Soil loss of the improved land was higher than that of the unimproved land in the top and bottom grasses in the first year. However, it was slightly higher in the unimproved land, and all of it were greatly decreased in the second year. 3. The percentage of grasses coverage was increased with the improved land in the first year, and it was not different between the improved land and unimproved land in the second year. Also, it was slightly increased in the bottom grasses. 4. Dry matter yield of grasses was increased with improved land at the top and bottom grasses. DM yield of grasses was increased in the top grasses in the first year and bottom grasses in the second year, respectively. 5. The establishment cost of grasses was decreased with wages decrement, and the management cost was saved about 1,116,000 won per ha with improved land. The results demonstrated that although soil loss was increased by leveling methods of improved land irrespective of pasture types in the first year, it was decreased with time little by little. Also, improved land was very good for grasses coverage, dry matter(DM) yield and economical value.

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요추추간판 탈충증에 대한 상체견인(V-trac)의 치료효과 연구 (Treatment Effects of Upper Body Traction (V-trac) for the HIVD)

  • 김명준;박지환
    • 대한물리치료과학회지
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    • 제2권4호
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    • pp.749-761
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    • 1995
  • The purpose of this study was to analyze the effects of V-trac on the clinical characteristics of patients who suffered from HIVD. The data were collected from 500 cases who had lumbar disc problems, from August, 1993 to July, 1995. The results of study were as follows; 1. Total patients statistics; mean age is 38 years, average duration of symptom is 5.4 years. 2. Symptomatic effects; HNP is 89.5 %, spinal stenosis is 55.1 %, and mean effects of total symptom is 80.0 %. 3. Pain relief effects; 1st session is 85.0 %, 7 th sessions are 89.3 %. 4. Back muscle improved effects; 10 sessions are 25.6 % rather than 1st session patients. 5. Sciatic scoliosis correction effect; Corrected scoliosis is improved 86.6 % by the 14 sessions V-trac. 6. Psychological effects; mental vigour is 51.2 %, emotional stability is 57.4 %, well-being is 72.5 %, comfortable sleeping is 60.2 %. 7. Follow-up states after V-trac therapy; Good conditions are 72.0 %, less conditions are 28.0 % after 1 month.

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Effects of Inclusion Levels of Dietary Vitamins and Trace Minerals on Growth Performance and Nutrient Digestibility in Growing Pigs

  • Chae, B.J.;Choi, S.C.;Cho, W.T.;Han, In K.;Sohn, K.S.
    • Asian-Australasian Journal of Animal Sciences
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    • 제13권10호
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    • pp.1440-1444
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    • 2000
  • Two feeding trials were conducted to evaluate the effects of inclusion levels of dietary vitamin and trace mineral (VTM) premixes on growth and nutrient digestibility in growing pigs. A total of 112 pigs ($24.82{\pm}3.22kg$) were employed for 49 days (exp. 1), and 168 pigs ($21.64{\pm}1.41kg$) for 40 days (exp. 2) in completely randomized block designs. Treatments were: 1) 100%, 2) 150%, 3) 200% and 4) 250% NRC (1998) requirement of VTM in exp. 1, and the ratio of vitamins to trace minerals at 1) 100:100%, 2) 100:150%, 3) 150:100% and 4) 150:150% of NRC (1998) requirement in exp. 2. Basal diets for feeding trials were formulated to contain 3,310 kcal ME/kg and 18% crude protein, and contained 0.25% chromic oxide as an indigestible marker for digestibility trials. Increasing dietary VTM premix in growing pigs had linear and quadratic effects (p<0.05) on ADG, and feed conversion ratio was also improved (p<0.05) as VTM premix was increased by 150-250% of NRC (1998) requirements in exp. 1. Adding vitamin to trace mineral premixes at 150% NRC (1998) over the control improved (p<0.05) ADG and feed efficiency in growing pigs, but performances were not improved by vitamin nor by trace mineral premixes alone (p>0.15) (exp. 2). There were no differences (p>0.05) in the digestibilities of energy, crude protein and fat among dietary treatments. However, increasing dietary VTM premix in growing pigs had a linear effect (p<0.05) on the digestibilities of calcium and phosphorus. The 200 or 250% fed group showed improved (p<0.05) calcium digestibility, and 250% fed group also showed improved (p<0.05) phosphorus digestibility as compared to 100% or 150% fed group (exp. 1). The digestibilities of Ca and P were higher (p<0.05) in 150% addition of vitamins than in 150% addition of trace minerals in the diet (exp. 2).

자기조절학습 수업 모형을 적용한 과학 수업이 초등학생의 학업적 자기조절능력 및 학업 성취, 과학에 관련된 정의적 특성에 미치는 영향 (Effects of Self-regulated Learning on Academic Self-regulation, Science Achievement and Science Related Affective Domains)

  • 정영란;안미경
    • 한국초등과학교육학회지:초등과학교육
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    • 제29권4호
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    • pp.389-400
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    • 2010
  • This study is focused on analyzing effects of Self-regulated learning on Academic self-regulation, Science achievement and Science Related Affective Domains. The subjects of this study were sampled from fifth grades of a elementary school in Seoul, 61 students. One class (31 students) out of selected two classes was applied to Self regulated learning Teaching Model, the other (30 students) took conventional methods of teaching. The experiment proceeded for 21 weeks, 51 times of classes. According to the results of this study, Self-regulated learning improved the children's Academic self regulation ability. Self-regulated learning improved the children's science achievement. Self-regulated learning improved the children's Science Related Affective Domains. Furthermore, six distinct dimensions of Academic self-regulation have correlation with scientific attitudes, interests of Science Related Affective Domains.

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방음벽 종류별 반사음 저감효과 및 회절효과에 관한 실험적 연구 (An Experimental Study on the Reduction Effect of Reflected Sound and Diffraction Effect by Types of Noise Barrier)

  • 김흥식
    • 소음진동
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    • 제6권2호
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    • pp.245-251
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    • 1996
  • This study is to suggest the improved noise barrier which is harmonized with surrounding landscape and maintained the similar reduction of reflected sound and diffraction effects in comparison with the aluminum noise barrier of absorbing type which is formed a great majority in Korea. In this study the two improved models of noise barrier(Diffuse and Disperse type) were designed and compared with the noise barriers of absorbing type in the acoustics performance (the reduction of reflected sound and diffraction effects) through the field and full-scale experimental measurement. As these two models have the same acoustic performance as the noise barrier of aluminum absorbing type, it is suggested that these models can be applied to the improved noise barrier as an alteration of aluminum absorbing type barrier.

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경험중심의 환경교육활동이 유아의 환경보존에 대한 인식에 미치는 효과 (The Effects of Field-trip Based Environmental Education on Young Children's Environmental Literacy)

  • 한영숙;최태식
    • 아동학회지
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    • 제26권6호
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    • pp.237-245
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    • 2005
  • The purpose of this study is to investigate the effects of field-trip based environmental education on young children's environmental literacy. The subjects for the study Were the 40 children of five years old at two nursery centers in province. The questionnaire and checklist for parents and the children developed by the researcher were used in this study. The conclusion were as follows. First, the care center environmental education improved the young children's saving, and anti-pollution depending on their mother is reported. Second, the care center environmental education improved the young children's saving, recycling and anti-pollution depending on their teacher is reported. Results showed that the field-trip based environmental education improved environmental literacy.

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샌드파일 설치지반에서의 복합지반효과 (A Study on Composite Ground Effects of Sand Piles)

  • 천병식;여유현
    • 한국지반공학회:학술대회논문집
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    • 한국지반공학회 2001년도 봄 학술발표회 논문집
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    • pp.397-404
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    • 2001
  • Sand pile is one of the widely used ground improvement methods. Sand pile improved ground will have composite ground effects, even though the primary purpose is the accelerated consolidation. However, the consolidation of sand pile improved ground as a composite ground is substantially under developed. This study investigate the effect of composite ground for relatively low volume displacement sand piles. Plate bearing tests and earth pressure cell measurements are performed. It turned out that the contribution of sand pile as a load bearing mechanism is not substantial. However the bearing capacity of the surrounding clayey soil is increased by sixty percent, and it cause the stiffness change during consolidation. Therefore it is expected that, the effect of increased stiffness of sand pile improved ground is influenced by change of ground stiffness.

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냉장 또는 동결우육에 있어서 저장기간과 재냉장이 연도에 미치는 영향 (Effects of Storage Period and Rechilling Process on Tenderness of Chilled or Frozen Beef)

  • 김미숙;문윤희
    • 한국축산식품학회지
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    • 제18권3호
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    • pp.216-223
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    • 1998
  • This study was conducted to investigate the effects of the tenderness for the vacuum chilled, the air-frozen or the rechilled Holstein beef loin. The vacuum packaged beef was stored at 1$^{\circ}C$ and the air-packaged beef was stored at -20$^{\circ}C$ for 60 days. The rechilled beef was restored for 3 days at 1$^{\circ}C$ by using the vacuum chilled or the air-frozen beef. Hardness and chewiness of the vacuum chilled beef were better than those of the air-frozen beef. Hardness and chewiness were improved significantly(p<0.05) after the 40 days storage for the vacuum chilled beef, but there was no significant improvement for the air-frozen beef during the 60 days storage. By the rechilling process, tenderness and myofibrillar fragmentation index of the vacuum chilled and air-frozen beef improved. Especially those were improved significantly(p<0.05) in the vacuum chilled beef after the 20 days storage, and in the air-frozen beef after the 40 and 60 days storage.

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