• 제목/요약/키워드: immunity

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범용 CMOS 공정을 사용한 DTMOS 슈미트 트리거 로직의 구현을 통한 EM Immunity 향상 검증 (DTMOS Schmitt Trigger Logic Performance Validation Using Standard CMOS Process for EM Immunity Enhancement)

  • 박상혁;김소영
    • 한국전자파학회논문지
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    • 제27권10호
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    • pp.917-925
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    • 2016
  • 슈미트 트리거 로직(Schmitt Trigger Logic)은 디지털 회로의 노이즈에 대한 내성을 향상시키기 위해 히스테리시스 특성을 보이는 게이트를 제안한 설계 방법이다. 슈미트 트리거 특성을 보이는 설계 방법 중 최근에 제안된 substrate bias를 조정하여 구현하는 Dynamic Threshold voltage MOS(DTMOS) 방법을 사용할 경우, 게이트 수를 늘이지 않고 내성을 향상 시킬 수 있는 설계방법이나, 범용 CMOS 공정에서 구현하여 시뮬레이션으로 예상하는 성능을 얻을 수 있는지는 검증되지 않았다. 본 연구에서는 $0.18{\mu}m$ CMOS 공정에서 DTMOS 설계 방법을 구현하여 히스테리시스 특성을 측정하여 검증하였다. DTMOS 슈미트 트리거 버퍼, 인버터, 낸드, 노어 게이트 및 간단한 디지털 로직 회로를 제작하였으며, 히스테리시스 특성, 전력 소모, 딜레이 등의 특성들을 관찰하고, 일반적인 CMOS 게이트로 구현된 회로와 비교하였다. 노이즈에 대한 내성이 향상되는 것을 Direct Power Injection(DPI) 실험을 통해 확인하였다. 본 논문을 통해 제작된 DTMOS 슈미트 트리거 로직은 10 M~1 GHz 영역에서 전자파 내성이 향상된 것을 확인할 수 있었다.

Overview of Innate Immunity in Drosophila

  • Kim, Tae-Il;Kim, Young-Joon
    • BMB Reports
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    • 제38권2호
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    • pp.121-127
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    • 2005
  • Drosophila protects itself from infection by microbial organisms by means of its pivotal defense, the so-called innate immunity system. This is its sole defense as it lacks an adaptive immunity system such as is found in mammals. The strong conservation of innate immunity systems in organisms from Drosophila to mammals, and the ease with which Drosophila can be manipulated genetically, makes this fly a good model system for investigating the mechanisms of virulence of a number of medically important pathogens. Potentially damaging endogenous and/or exogenous challenges sensed by specific receptors initiate signals via the Toll and/or Imd signaling pathways. These in turn activate the transcription factors Dorsal, Dorsal-related immune factor (Dif) and Relish, culminating in transcription of genes involved in the production of antimicrobial peptides, melanization, phagocytosis, and the cytoskeletal rearrangement required for appropriate responses. Clarifying the regulatory interactions between the various pathways involved is very important for understanding the specificity and termination mechanism of the immune response.

Characteristics of 14-3-3 Proteins and Their Role in Plant Immunity

  • Oh, Chang-Sik
    • The Plant Pathology Journal
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    • 제26권1호
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    • pp.1-7
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    • 2010
  • Phosphorylation is a major post-translational modification of proteins that regulate diverse signal transduction pathways in eukaryotic cells. 14-3-3 proteins are regulatory proteins that bind to target proteins in a phosphorylation-dependent manner and have been shown to play an important role in plant growth and development, primary metabolism, and signal transduction. Because phosphorylation plays a critical role in signal transduction pathways to trigger plant immunity, involvement of 14-3-3 proteins in plant immunity has been suggested for a long time. Recent studies have provided new evidence to support a role for 14-3-3 proteins in plant immunity. This review will briefly discuss general characteristics of 14-3-3 proteins and their involvement in plant immunity.

Regulation of Intestinal Homeostasis by Innate Immune Cells

  • Kayama, Hisako;Nishimura, Junichi;Takeda, Kiyoshi
    • IMMUNE NETWORK
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    • 제13권6호
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    • pp.227-234
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    • 2013
  • The intestinal immune system has an ability to distinguish between the microbiota and pathogenic bacteria, and then activate pro-inflammatory pathways against pathogens for host defense while remaining unresponsive to the microbiota and dietary antigens. In the intestine, abnormal activation of innate immunity causes development of several inflammatory disorders such as inflammatory bowel diseases (IBD). Thus, activity of innate immunity is finely regulated in the intestine. To date, multiple innate immune cells have been shown to maintain gut homeostasis by preventing inadequate adaptive immune responses in the murine intestine. Additionally, several innate immune subsets, which promote Th1 and Th17 responses and are implicated in the pathogenesis of IBD, have recently been identified in the human intestinal mucosa. The demonstration of both murine and human intestinal innate immune subsets contributing to regulation of adaptive immunity emphasizes the conserved innate immune functions across species and might promote development of the intestinal innate immunity-based clinical therapy.

전자파내성시험용 측정시스템의 개발에 관한 연구 (Development of Electromagnetic Wave Immunity Test system)

  • 정세모;김동일;배대환
    • 한국항해학회지
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    • 제20권2호
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    • pp.97-107
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    • 1996
  • The method of Electromagnetic Wave Immunity Test is continuously endeavored by IEC and CISPR as international unification, but it has not been established yet. The main reason is why it is difficult to obtain the measurement method and normalization of threshold to find out the complicated parameters for Electromagnetic Wave immunity Test. So far, thus, the Electromagnetic Wave Immunity Test is carried out case by case as the electromagnetic environment, which is set up Electromagnetic Wave Immunity Test. This study has developed an algorithm and measurement software suitable for IEC1000-4 Regulations, where a ready-made Amplifier, and Signal Generator have been used and an interconnecting Interface Board has been constructed for connecting with the other apparatuses, i.e., RF Switch, Power Meter, Field Sensor, Pre-Amp., etc. Therefore, we have achieved the aim to develop an automated software using OOP method and the measurement system.

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현대에서의 생백신과 이에 대한 면역반응의 재평가 (Reappraisal of Live Vaccines and Immunity in These Modern Days)

  • 김경효
    • Pediatric Infection and Vaccine
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    • 제16권1호
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    • pp.24-30
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    • 2009
  • The vaccines has been developed over the first two hundred years since Jenner's smallpox vaccination. In modern days, vaccination has had the largest impact on the incidence and persistence of infections. Although natural infection induces lifelong immunity, the assumption that the vaccine also confers permanent protection has been reconsidered following outbreaks of measles in students who had been vaccinated 15-20 years prior to infection in the US in the 1980s. Clinical studies have proposed several mechanisms such as vaccine failure in some individuals and the subsequent loss of immunity after vaccination. An ideal vaccine is relatively easy to define, but few real vaccines approach the ideal. Many difficulties account for the failure in producing these ideal vaccines. However, recent advances in methods for studying immune response to pathogens have provided a better understanding of immune mechanisms. Based on these findings, the development of good vaccine formulations allowing stimulation of optimal and prolonged protective immunity and immunization policies or schedules should lead to the introduction of vaccines for previously resistant organisms.

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첨단자동차의 전자파 내성 실험 환경에 관한 연구: 외부통신 장치를 중심으로 (Electromagnetic Immunity Test Environments of Advanced Vehicles with Communication Systems)

  • 우현구
    • 자동차안전학회지
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    • 제14권1호
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    • pp.14-19
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    • 2022
  • Recently, automobile industries have developed ADAS, smart cars, connected cars, automated driving systems, which communicate with outsides of a vehicle not only in uni-directional way but also in bi-directional way. It is necessary to examine the electromagnetic immunity of vehicles equipped with those communication systems. The electromagnetic immunity tests are carried out in an electromagnetic semi anechoic chamber, which is cut off from the outside electromagnetically. In this study, additional test environments were designed and tested and as a result they are shown to be effective to create test environments in an experimental chamber for electromagnetic immunity tests of vehicles equipped with communication systems.

해양안보 위협요인으로서의 타국 정부선박에 대한 관할권 제한 (The restriction of jurisdiction on foreign government ships as a threatening factor on maritime security)

  • 이민효
    • 한국정보통신학회논문지
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    • 제14권7호
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    • pp.1729-1736
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    • 2010
  • 비상업용 정부선박은 국가가 소유 운영하는 선박으로 군함과 마찬가지로 타국 재판관할권으로부터 면제된다. 이는 전통 국제법상의 주권면제이론에 따른 것으로, 국제법상 국가 행위나 재산은 타국의 재판권으로부터 면제되기 때문이다. 주권면제는 판례나 국가관행을 통해 확립된 일반 국제법상의 원칙이다. 문제는 우리 관할수역에서의 타국 비상업용 정부선박에 대한 관할권 제한은 해양안보적 측면에서 상당한 불안요인이 된다는 점이다. 왜냐하면 불순한 의도로 우리 관할수역에 들어와도 주권면제가 인정되기 때문에 그 대응에는 한계가 있을 수밖에 없다. 국제법이나 국제관례를 벗어난 관할권 집행은 국제사회의 비난은 물론 국가책임을 발생시키기 때문에 관련 국제규범의 정확한 이해 및 적용을 통한 합법적 권한행사가 중요하다.

누전차단기의 EMC 조합서지 내성 강화를 위한 방안 (The Method of Reinforcing the Immunity of Residual Current Circuit Breaker for the EMC Composite Surge)

  • 김재철;한윤탁;김언석;설규환;강장규;문종필
    • 대한전기학회논문지:전력기술부문A
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    • 제55권8호
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    • pp.322-328
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    • 2006
  • In this paper, The impulse un-tripping characteristics and the electro magnetic compatibility characteristics are compared with each other. The performance of impulse un-tripping test exists at domestic standard (KSC 4613). However test items are insufficient because the more test items such as EMC exist at international standard (IEC). Also, Electric Appliances Safety Certificate has taken the certificate test since July 2004 in Korea but did not confirm the EMC performance for RCCBs made in Korea. Thus, in this paper, We experiment with Oscillatory waves immunity test and the 7 EMC tests for 32 RCCBs of 4 types (mini, home standard, plug, outlet) for 16 brands according to IEC standard 61009-1 and 61008-1. As a result, 24 RCCBs proved to be poor for surge immunity test. However the RCCBs operating incorrectly for surge immunity test operate correctly for oscillatory waves immunity test. Thus, the correlation between oscillatory waves immunity test and EMC test is little and standard for compatibility of combination surge at IEC 61000-4-5 should be added to KS standard as soon as possible.

부정적 정보에 대한 패션브랜드 면역에의 영향요인과 브랜드 몰입과의 관계 연구 (Antecedents of Fashion Brand Immunity to Negative Information and Impact on Brand Commitment)

  • 김한나;이은정
    • 한국의류학회지
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    • 제35권7호
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    • pp.856-866
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    • 2011
  • This study examines how brands can be managed to influence the degree of their resistance to negative information and the extent to which this immunity to negative information predicts the purchase intention of consumers. In particular, the study investigated the difference between brand commitment and brand immunity on negative information in terms of the concept and the power of influence. A total of 410 usable questionnaires were obtained through an internet survey. A structural equation model using a correlation matrix with maximum likelihood was estimated using AMOS 18.0 to examine the relationship among a brand's social responsibility, quality orientation, brand innovativeness, easy purchase intention, and difficult purchase intention. The results showed that brand's social responsibility had significant effects on brand immunity to negative information while quality orientation and brand innovativeness had significant effects on brand commitment. In addition, brand immunity had significant effects on brand commitment and then brand commitment had a significant effect on easy and difficult purchase intentions. The key implications for research and management are discussed.