• Korean Journal of Radiology
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• 제24권8호
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• pp.772-783
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• 2023

Objective: Imaging-based survival stratification of patients with gliomas is important for their management, and the 2021 WHO classification system must be clinically tested. The aim of this study was to compare integrative imaging- and pathology-based methods for survival stratification of patients with diffuse glioma. Materials and Methods: This study included diffuse glioma cases from The Cancer Genome Atlas (training set: 141 patients) and Asan Medical Center (validation set: 131 patients). Two neuroradiologists analyzed presurgical CT and MRI to assign gliomas to five imaging-based risk subgroups (1 to 5) according to well-known imaging phenotypes (e.g., T2/FLAIR mismatch) and recategorized them into three imaging-based risk groups, according to the 2021 WHO classification: group 1 (corresponding to risk subgroup 1, indicating oligodendroglioma, isocitrate dehydrogenase [IDH]-mutant, and 1p19q-codeleted), group 2 (risk subgroups 2 and 3, indicating astrocytoma, IDH-mutant), and group 3 (risk subgroups 4 and 5, indicating glioblastoma, IDHwt). The progression-free survival (PFS) and overall survival (OS) were estimated for each imaging risk group, subgroup, and pathological diagnosis. Time-dependent area-under-the receiver operating characteristic analysis (AUC) was used to compare the performance between imaging-based and pathology-based survival model. Results: Both OS and PFS were stratified according to the five imaging-based risk subgroups (P < 0.001) and three imaging-based risk groups (P < 0.001). The three imaging-based groups showed high performance in predicting PFS at one-year (AUC, 0.787) and five-years (AUC, 0.823), which was similar to that of the pathology-based prediction of PFS (AUC of 0.785 and 0.837). Combined with clinical predictors, the performance of the imaging-based survival model for 1- and 3-year PFS (AUC 0.813 and 0.921) was similar to that of the pathology-based survival model (AUC 0.839 and 0.889). Conclusion: Imaging-based survival stratification according to the 2021 WHO classification demonstrated a performance similar to that of pathology-based survival stratification, especially in predicting PFS.

• ETRI Journal
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• 제27권3호
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• pp.289-293
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• 2005

We propose an asymmetric integral imaging method to adjust the resolution and depth of a three-dimensional image. Our method is obtained by use of two lenticular sheets with different pitches fabricated under the same F/#. The asymmetric integral imaging is the generalized version of integral imaging, including both conventional integral imaging and one-dimensional integral imaging. We present experimental results to test and verify the performance of our method computationally.

• 전기학회논문지
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• 제61권6호
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• pp.879-884
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• 2012

Photoacoustic Tomography (PAT) is a promising medical imaging modality by reason of its particularity. It combines optical imaging contrast of optical imaging with the spatial resolution of ultrasound imaging and can demonstrate change of biological feature in an image. For that reason, many studies are in progress to apply this technic for diagnosis. But, real-time PAT system is necessary to confirm a biological reaction induced by external stimulation immediately. Thus, we developed a real-time PAT system using linear array transducer and self-developed Data acquisition board (DAQ) resources, To evaluate the feasibility and performance of our proposed system, two type of phantom test were also performed. As a result of those experiments, the proposed system shows enough performance and confirm its usefulness.

• Nuclear Engineering and Technology
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• 제54권3호
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• pp.1016-1023
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• 2022

In proton therapy, a highly conformal proton dose can be delivered to the tumor by means of the steep distal dose penumbra at the end of the beam range. The proton beam range, however, is highly sensitive to range uncertainty, which makes accurately locating the proton range in the patient difficult. In-vivo range verification is a method to manage range uncertainty, one of the promising techniques being prompt gamma imaging (PGI). In earlier studies, we proposed gamma electron vertex imaging (GEVI), and constructed a proof-of-principle system. The system successfully demonstrated the GEVI imaging principle for therapeutic proton pencil beams without scanning, but showed some limitations under clinical conditions, particularly for pencil beam scanning proton therapy. In the present study, we upgraded the GEVI system in several aspects and tested the performance improvements such as for range-shift verification in the context of line scanning proton treatment. Specifically, the system showed better performance in obtaining accurate prompt gamma (PG) distributions in the clinical environment. Furthermore, high shift-detection sensitivity and accuracy were shown under various range-shift conditions using line scanning proton beams.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2012년도 추계학술대회
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• pp.1012-1014
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• 2012

집적 영상 (integral imaging) 기술은 렌즈배열을 이용하여 3D 영상을 공간상에 표시할 수 있어서 차세대 유망 3D 디스플레이 기술 중에 하나이다. 집적 영상 시스템의 성능은 디스플레이 장치, 렌즈 배열, 이미징 광학 장비 등에 매우 의존적이다. 본 논문에서는 제한된 리소스에서 집적 영상 시스템의 해상도 분석을 수행하는 해석 방법을 제안한다. 제안하는 방법을 통하여 해상도 측면에서 최적화된 집적 영상 시스템 설계를 수행할 수 있다. 제안하는 방법의 유용함을 위하여 Monte Carlo 시뮬레이션을 수행하고 그 결과를 보고한다.

• 한국군사과학기술학회지
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• 제15권5호
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• pp.687-698
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• 2012

LADAR systems can rapidly acquire 3D point clouds by sampling the target surfaces using laser pulses. Such point clouds are widely used for diverse applications such as DSM/DTM generation, forest biomass estimation, target detection, wire avoidance and so on. Many kinds of LADAR systems have been developed with their respective purposes and applications. Particularly, Geiger mode imaging LADAR systems are increasingly utilized since they are energy efficient thank to extremely sensitive detectors incorporated into the systems. The purpose of this research is the performance assessment of a Geiger mode imaging LADAR system based on simulation with the real system parameters. We thus developed a simulation method of such a LADAR system by modeling its geometric, radiometric, optic and electronic aspects. Based on the simulation, we performed the performance assessment of a newly designed system to derive the outlier ratio and false alarm rate expected during its operation in almost real environment with reasonable system parameters. The proposed simulation and performance assessment method will be effectively utilized for system design and optimization, and test data generation.

• 반도체디스플레이기술학회지
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• 제15권3호
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• pp.35-39
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• 2016

Extreme Ultraviolet Lithography (EUVL) is the most promising technique in the field of Next Generation Lithography (NGL) expected to be used in the 1x-nm node for High Volume Manufacturing (HVM). But there exits remaining challenges for proper defect control of EUV mask. It was considered development of EUV pellicle for protecting the EUV mask has many obstacles due to high extinction coefficient of EUV wavelength. Recently researchers in the industry of semiconductor argue about the necessity of EUV pellicle and make effort to achieve it. In this paper, we investigated that the relationship between imaging performance and transmittance of EUV pellicle quantitatively. We made in-house EUV pellicle and analyzed its imaging performance of the dependence of pellicle transmittance using Coherent Scattering Microscopy(CSM). The imaging performance of EUV mask with pellicle is affected by its transmittance and we found that the performance of EUV mask improved with higher transmittance pellicle.

• 한국군사과학기술학회지
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• 제13권2호
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• pp.328-335
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• 2010

A hyperspectral imaging spectrometer has shown significant advantages in performance over other existing ones for remote sensing applications. It can collect hundreds of narrow, adjacent spectral bands for each image, which provides a wealth of information on unique spectral characteristics of objects. We have developed a compact hyperspectral imaging system that successively shows high spatial and spectral resolutions and fast data processing performance. In this paper, we present an overview of the hyperspectral imaging system including the strucure of geometrical optics and several image processing schemes such as wavelength calibration and noise reduction for image data on Visible and Near-Infrared(VNIR) and Shortwave-Infrared(SWIR) band.

• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2006년 제4회 한국유체공학학술대회 논문집
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• pp.475-478
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• 2006

In electrical impedance tomography (EIT) an array of electrodes is attached on the boundary of an object and small alternating currents are injected through these electrodes, and then the resulting voltages are measured. An estimation for the cross-sectional resistivity distribution in the object is obtained by using these current and voltage data in a nondestructive manner. In this paper, the electrical impedance imaging of two-phase flows undergoing rapid transient is considered with a special emphasis on the effect of the current pattern on the image reconstruction. The trigonometric current pattern, which is commonly used in the conventional static electrical impedance imaging, shows poor performance in case of the dynamic imaging considered in this work. Extensive numerical experiments are conducted with various kinds of current patterns and their effects on the image reconstruction performance are examined.

• 품질경영학회지
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• 제49권1호
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• pp.47-60
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• 2021

Purpose: This study proposes methods and procedures for evaluating imaging security systems quality of cabinet x-ray screening system to enhance performance certification technology. Also, conducted a comparative analysis of the literature of test-kit for imaging security quality evaluation. Methods: Comparative analysis of the test-kits and related documents for image quality assessment of cabinet x-ray screening equipment. This allows assessment items were selected and the methods for each assessment item were proposed. In addition, the configuration method of the assessment team was established by applying the technology readiness assessment(TRA). Results: Four of the assessment items were selected when estimate image quality by a comparative analysis of literature. For each assessment item, the evaluation method and minimum level of availability were determined. Finally, this paper proposes an imaging quality assessment of cabinet X-ray imaging security systems. Conclusion: Development of imaging security systems evaluation procedures for cabinet X-ray screening systems can be help improve performance certification of aviation security equipment.