• Investigative Magnetic Resonance Imaging
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• v.25 no.3
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• pp.141-155
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• 2021

Purpose: To develop a 3D magnetic resonance fingerprinting (MRF) method for application in high resolution knee cartilage PD, T₁, T₂ mapping. Materials and Methods: A novel 3D acquisition trajectory with golden-angle rotating radial in k_xy direction and interleaved echo planar imaging (EPI) acquisition in the k_z direction was implemented in the MRF framework. A centric order was applied to the interleaved EPI acquisition to reduce Nyquist ghosting artifact due to field inhomogeneity. For the reconstruction, singular value decomposition (SVD) compression method was used to accelerate reconstruction time and conjugate gradient sensitivity-encoding (CG-SENSE) was performed to overcome low SNR of the high resolution data. Phantom experiments were performed to verify the proposed method. In vivo experiments were performed on 6 healthy volunteers and 2 early osteoarthritis (OA) patients. Results: In the phantom experiments, the T₁ and T₂ values of the proposed method were in good agreement with the spin-echo references. The results from the in vivo scans showed high quality proton density (PD), T₁, T₂ map with EPI echo train length (N_ETL = 4), acceleration factor in through plane (R_z = 5), and number of radial spokes (N_spk = 4). In patients, high T₂ values (50-60 ms) were seen in all transverse, sagittal, and coronal views and the damaged cartilage regions were in agreement with the hyper-intensity regions shown on conventional turbo spin-echo (TSE) images. Conclusion: The proposed 3D MRF method can acquire high resolution (0.5 mm³) quantitative maps in practical scan time (~ 7 min and 10 sec) with full coverage of the knee (FOV: 160 × 160 × 120 mm³).

• Tuberculosis and Respiratory Diseases
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• v.61 no.5
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• pp.433-439
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• 2006

Background: Although airway hyper-responsiveness is one of the characteristics of asthma. bronchial hyper-responsiveness has also been observed to some degree in patients with chronic obstructive pulmonary disease (COPD). Moreover, several reports have demonstrated that a number of patients have both COPD and asthma. The methacholine bronchial challenge test (MCT) is a widely used method for the detecting and quantifying the airway hyper- responsiveness, and is one of the diagnostic tools in asthma. However, the significance of MCT in differentiating asthma or COPD combined with asthma from pure COPD has not been defined. The aim of this study was to determine the role of MCT in differentiating asthma from pure COPD. Method: This study was performed prospectively and was composed of one hundred eleven patients who had undergone MCT at Chonbuk National University Hospital. Sixty-five asthma patients and 23 COPD patients were enrolled and their MCT data were analyzed and compared with the results of a control group. Result: The positive rates of MCT were 65%, 30%, and 9% in the asthma, COPD, and control groups, respectively. The mean $PC_{20}$ values of the asthma, COPD, and control groups were $8.1{\pm}1.16mg/mL$, $16.9{\pm}2.21mg/mL$, and $22.0{\pm}1.47mg/mL$, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of MCT for diagnosing asthma were 65%, 84%, 81%, and 69%, respectively. The sensitivity, specificity, positive predictive value, and negative predictive value of MCT (ed note: please check this as I believe that these values correspond to the one $PC_{20}$ value. Please check my changes.) at the new cut-off points of$PC_{20}{\leq}16mg/ml$, were 80%, 75%, 78%, and 78%, respectively. Conclusion: MCT using the new cut-off point can be used as a more precise and useful diagnostic tool for distinguishing asthma from pure COPD.

• The Journal of the Korea institute of electronic communication sciences
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• v.15 no.1
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• pp.161-166
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• 2020

This paper suggests an extension of the unified Bayesian Tikhonov regularization method. The unified method establishes the relationship between Tikhonov regularization parameter and Bayesian hyper-parameters, and presents a formula for obtaining the regularization parameter using the maximum posterior probability and the evidence framework. When the dimension of the data matrix is m by n (m >= n), we derive that the total misfit has the range of m ± n instead of m. Thus the search range is extended from one to 2n + 1 integer points. Golden section search rather than linear one is applied to reduce the time. A new benchmark for optimizing relative error and new model selection criteria to target it are suggested. The experimental results show the effectiveness of the proposed method in the image restoration problem.

• Journal of The Korean Association of Information Education
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• v.10 no.1
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• pp.37-46
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• 2006

We expected that PBL (Problem based Learning) methode has good effectiveness for HTML(Hyper Text Markup Language) learning of elementary school students. In this study, a test was conducted in which a PBL method and the traditional lecture-based learning method were applied to an HTML class, and compared the level of educational accomplishment and compared the effectiveness of the two methods. PBL applied was based on the IMSA model of problem-based learning center. Educational accomplishment was evaluated base d on evaluation of theory and application skills. Test results revealed that there were no significant differences in theoretic learning between the two methods of learning. However, in application skills, the PBL was proved to be significantly more effective th an the traditional lecture-based learning method. Through the study, it was verified that PBL has a more positive educational effect that the traditional lecture-based learning.

• Journal of Engineering Education Research
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• v.19 no.1
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• pp.31-36
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• 2016

These days, ICT-related products are pouring out due to development of mobile technology and increase of smart phones. Among the ICT-related products, wearable devices are being spotlighted with the advent of hyper-connected society. In this paper, a body-attached type wearable device using EMG(electromyography) sensors is studied. The research field of EMG sensors is divided into two parts. One is medical area and another is control device area. This study corresponds to the latter that is a method of transmitting user's manipulation intention to robots, games or computers through the measurement of EMG. We used commercial device MYO developed by Thalmic Labs in Canada and matched up EMG of arm muscles with gesture controller. In the experiment part, first of all, various arm motions for controlling devices are defined. Finally, we drew several distinguishing kinds of motions through analysis of the EMG signals and substituted a joystick with the motions.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.1
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• pp.49.2-49.2
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• 2015

IntraCluster Medium (ICM) located at the galaxy cluster is in the state of very hot, tenuous, magnetized, and highly ionized X-ray emitting plasmas. High temperature and low density make ICM very viscous and conductive. In addition to the high conductivity, fluctuating random plasma motions in ICM, occurring at all evolution stages, generate and amplify the magnetic fields in such viscous ionized gas. The amplified magnetic fields in reverse drive and constrain the plasma motions beyond the viscous scale through the magnetic tension. Moreover, without the influence of resistivity viscous damping effect gets balanced only with the magnetic tension in the extended viscous scale leading to peculiar ICM energy spectra. This overall collisionless magnetohydrodynamic (MHD) turbulence in ICM was simulated using a hyper diffusivity method. The results show the plasma motions and frozen magnetic fields have power law of $E_V^k{\sim}k^{-3}$, $E_M^k{\sim}k^{-1}$. To explain these abnormal power spectra we set up two simultaneous differential equations for the kinetic and magnetic energy using an Eddy Damped Quasi Normal Markovianized (EDQNM) approximation. The solutions and dimensions of leading terms in the coupled equations derive the power spectra and tell us how the spectra are formed. We also derived the same results with a more intuitive balance relation and stationary energy transport rate.

• Korean Institute of Interior Design Journal
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• v.27 no.2
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• pp.86-97
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• 2018

In modern times, pluralistic social phenomena in which various values are pursed and recognized appear. The modern society called hyper-connected, intelligence information and zero marginal cost society in which shared value is commonly emphasized faces a paradigm shift to shared society system. In particular, sharing-based activities related with intelligence information sectors more prominently emerge in the high-tech informatization which has been accelerated. The purpose of this study is to understand design factors related with how attribution of the sharing culture is expressed in library spaces and examine how sharing infrastructure is established in users' spaces. As a research method, it initially conducted theoretical consideration of the sharing culture and information spaces, which can be regarded as sociocultural phenomena in modern times. Then, it drew sharing culture-based spatial design factors-access, openness and plurality. It analyzed configuration of spaces for sharing information-Cultural Commons (CC), Information Commons(IC) and Learning Commons (LC) - and infrastructure of information spaces, for library cases-five domestic and foreign public libraries-. The findings show that modern library spaces reflect historical needs for the sharing culture and actively serve their roles through spatial infrastructure including contents (programs) and services for sharing knowledge. The study is determined to be valuable as basic data in establishing the infrastructure of information spaces reflecting modern social trends and cultural phenomena, in expecting spatial structures in which knowledge is reproduced and planning spaces of libraries in the future.

• The Journal of the Convergence on Culture Technology
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• v.4 no.2
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• pp.155-160
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• 2018

In this study, the experiments for surface enhancement of silver mirror substrates were done, where we checked the characteristics of silver surface made by Tollen's and ${\gamma}$- irradiation method. The surface enhancement of Indigo carmine was analyzed by silver mirror and silver sol surfaces. The assignments of the vibrational bands shown in SERS spectra are given based on both literature and the semi-empirical calculations at the PM3 methods. We deduced that the adsorption orientation of Indigo carmine was little tilted perpendicular to the silver surfaces by using of the surface selection rules.

• Journal of Korean Academy of Nursing
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• v.10 no.1
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• pp.29-40
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• 1980

A Study on environmental factors influencing blood pressure control of a patient with essential pressure hyper -tension was conduct to the identification of differences of demographic characteristics, socioeconomic factors and living habits. This study was performed on 219 cases who were divided into two groups from Sept. 14 to Oct. 20, 1979. One is the group with complication in the departments of internal medicine and outpatient of 7 hospitals in Seoul. The other is the group without complication in the same places as above. The instrument applied to this study consists of 19 items amended through preliminary test after consideration of related literatural review and Nursing History made by Smith (1965）. The materials were analyzed by computer program. The findings were as follows : 1. The group with complication had more sleep disturbances than the group without complication 2. The group with complication used more short term coping method on stress than the group without complication. 3. The group with complication had a tendency to more intake of salt, fat, alcohols and cigretts than the group without complition, but there were no significant differences between two groups. 4. The group with complication were lower social class than the group without complication. 5. The group with complication were more single(Death of spouse, Divorce, Separation) in marital status than the group without complication.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.28 no.10
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• pp.1574-1582
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• 2004

Binary manipulators have recently received much attention due to hyper-redundancy, light weight, good controllability and high reliability. The precise positioning of the manipulator end-effecter requires the use of many modules, which results in a high-dimensional workspace. When the workspace dimension is large, existing inverse kinematics methods such as the Ebert-Uphoff algorithm may require impractically large memory size in determining the binary positions of all actuators. To overcome this limitation, we propose a new inverse kinematics algorithm: the inverse kinematics problem is formulated as an optimization problem using real-valued design variables, The key procedure in this approach is to transform the integer-variable optimization problem to a real-variable optimization problem and to push the real-valued design variables as closely as possible to the permissible binary values. Since the actual optimization is performed in real-valued design variables, the design sensitivity becomes readily available, and the optimization method becomes extremely efficient. Because the proposed formulation is quite general, other design considerations such as operation power minimization can be easily considered.