• Journal of Genetic Medicine
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• v.16 no.2
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• pp.62-66
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• 2019

Harlequin ichthyosis (HI, OMIM #242500) is one of the most severe skin diseases among the autosomal recessive congenital ichthyoses, with high morbidity and mortality, particularly in newborns. Clinically, it is characterized by a typical appearance of generalized, thick, yellowish, hyperkeratotic plates with deep erythematous fissures on the skin. Herein, we present the case of a newborn girl with HI that was genetically confirmed by targeted gene panel analysis. The premature baby was encased in an opaque white membrane with erosion covering the skin of the entire body except the lips, with her hands and feet restricted by the membrane. Humidification, emollient, and retinoic acid treatment were started; the thick ichthyosis gradually peeled off and the underlying skin was only covered with thin scales. Targeted gene panel analysis using next-generation sequencing and validation with Sanger sequencing and quantitative polymerase chain reaction analyses confirmed compound heterozygous mutations of the ABCA12 gene (p.N1380S and a partial gene deletion encompassing exon 9). The parents were carriers for each of the identified mutations. Early recognition of the genetic etiology of congenital ichthyosis can, thus, facilitate genetic counseling for patients and their families.

• Journal of Yeungnam Medical Science
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• v.6 no.2
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• pp.39-46
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• 1989

The tracheobronchial histopathologic findings in 7 healthy cats used with high frequency oscillation ventilation (HFOV) were compared with those in 6 cats used with conventional mechanical ventilation (CMV). 4-point, 9-variable scoring system was used to evaluate the injury in the trachea, right & left main bronchi and parenchyme. The following results were obtained ; 1) The tracheobronchial tree received HFOV had no significant damage compared with CMV (P>0.05). 2) Intraepithelial mucus loss and emphysema were s lightly more prominent in CMV groups. As above results ; the tracheobronchial histopathologic difference was not prominent between CMV and HFOV groups received with relatively short period, however, the cellular function and barotrauma may be more prominent in CMV groups. From now on, as causes of tracheobronchial injury in HFV, interaction between humidification and mechanical trauma considers further study.

• Journal of Navigation and Port Research
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• v.33 no.4
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• pp.289-294
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• 2009

The living performances of crews and passengers in cabins have been less received attention, while Korea is a top leading country in ship building industry. To develop a high value added ships like 5-star cruisers, researches on the comfort and productivity in cabins should be carried out with urgent. The purpose of this study is to measure and analyze of the ship's indoor thermal conditions in spring, summer and winter, and also to compare the seasonal differences, of which conditions are supplied from and controlled by marine HVAC The temperature, humidity and air supply volume of 5 different needs of cabins on a training ship were measured through a year, which was launched at Dec. 2005 and totally 246 crews can go on board for education. The following results were obtained: (1)In the spring, the temperature in cabins was measured as $20{\sim}25^{\circ}C$ and humidity was below 30%. (2)In the summer, the temperatures was controlled at $21{\sim}27^{\circ}C$ in almost cabins and humidity was between $40{\sim}60%$ which is known as comfort conditions. (3)In the winter, temperature and humidity was maintained between $19{\sim}26^{\circ}C$, and humidity was between $10{\sim}50%$. (4)It is clear that the humidity conditions in cabins are not properly controlled at all through a year to satisfy the Comfort Standards provided by ASHRAE and/or ISO, In conclusion, humidification and dehumidification of cabins must be treated with importance for more comfort living and working environments for crews and passengers.

• Journal of the Korean Wood Science and Technology
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• v.44 no.3
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• pp.424-429
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• 2016

In this study, the carbonized boards were manufactured from different types of wood-based panel and then their moisture absorption/desorption properties were investigated and compared. The carbonization temperature was maximum $600^{\circ}C$ with 2 h maintains. Test results showed higher absorption/desorption capacity on carbonized plywood than carbonized MDF, PB, and OSB, respectively. However, carbonized MDF, OSB, and plywood had similar absorption/desorption rate per hour. It means carbonized OSB and plywood can transfer moisture into deeper side and then possibly hold more amount of water. Based on SEM images, carbonized OSB and plywood showed more like wood structure, while carbonized MDF and PB had only wood fiber or/and chunk of wood fragments. Therefore, original wood structure may affect moisture absorption/desorption capacity. In order to manufacture high moisture absorbing/desorbing carbonized board, wood structure should be considered and then carbonized.

• Journal of the Korean Electrochemical Society
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• v.15 no.1
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• pp.35-40
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• 2012

The composite membranes using Nafion as matrix and 1-ethyl-3-methylimidazolium tetracyanoborate (EMITCB) as ion-conducting medium in replacement of water were prepared and characterized. The amount of EMITCB in Nafion varied from 30 to 50wt%. The composite membranes are characterized by ion conductivity, thermogravitational analyses (TGA) and small-angle X-ray scattering (SAXS). The composite membranes containing EMITCB of 40wt% showed the maximum ionic conductivity which was ~0.0146 S $cm^{-1}$ at 423.15 K. It is inferred that the decrease in ionic conductivity of all the composite membranes might be due to the decomposition of a tetracyanoboric acid formed in the composite membranes. The results of SAXS indicated that the ionic clusters to conduct proton in the composite membranes were successfully formed. In accordance with the results of ionic conductivity as a function of a reciprocal temperature, SAXS showed a proportional decrease in scattering maximum $q_{max}$ as the amount of EMITCB increases in the composite membranes, which results in the increase in ionomer cluster size. The TGA showed no significant decomposition of the ionic liquid as well as the composite membranes in the range of operating temperature ($120-150^{\circ}C$) of high temperature proton exchange membrane fuel cells (HTPEMFC). As a result, EMITCB is able to play an important role in transferring proton in the composite membranes at elevated temperatures with no external humidification for proton exchange membrane fuel cells.

• Applied Chemistry for Engineering
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• v.29 no.5
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• pp.489-496
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• 2018

Fuel cells are seen as eco-friendly energy resources that convert chemical energy into electrical energy. However, proton exchange membrane fuel cells (PEMFCs) have problems such as the use of expensive platinum catalysts for the reduction of conductivity under high temperature humidification conditions. Thus, an anion exchange membrane fuel cell (AEMFC) is attracting a great attention. Anion exchange fuel cells use non - Pt catalysts and have the advantage of better efficiency because of the lower activation energy of the oxygen reduction reaction. However, there are various problems to be solved including problems such as the electrode damage and reduction of ion conductivity by being exposed to the carbon dioxide. Therefore, this mini review proposes various solutions for different problems of anion exchange fuel cells through a wide range of research papers.

• Archives of Plastic Surgery
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• v.41 no.4
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• pp.330-336
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• 2014

Background For patients with full thickness skin defects, autologous Split-thickness skin grafts (STSG) are generally regarded as the mainstay of treatment. However, skin grafts have some limitations, including undesirable outcomes resulting from scars, poor elasticity, and limitations in joint movement due to contractures. In this study, we present outcomes of Matriderm grafts used for various skin tissue defects whether it improves on these drawbacks. Methods From January 2010 to March 2012, a retrospective review of patients who had undergone autologous STSG with Matriderm was performed. We assessed graft survival to evaluate the effectiveness of Matriderm. We also evaluated skin quality using a Cutometer, Corneometer, Tewameter, or Mexameter, approximately 12 months after surgery. Results A total of 31 patients underwent STSG with Matriderm during the study period. The success rate of skin grafting was 96.7%. The elasticity value of the portion on which Matriderm was applied was 0.765 (range, 0.635-0.800), the value of the trans-epidermal water loss (TEWL) was 10.0 (range, 8.15-11.00)$g/hr/m^2$, and the humidification value was 24.0 (range, 15.5-30.0). The levels of erythema and melanin were 352.0 arbitrary unit (AU) (range, 299.25-402.75 AU) and 211.0 AU (range, 158.25-297.00 AU), respectively. When comparing the values of elasticity and TEWL of the skin treated with Matriderm to the values of the surrounding skin, there was no statistically significant difference between the groups. Conclusions The results of this study demonstrate that a dermal substitute (Matriderm) with STSG was adopted stably and with minimal complications. Furthermore, comparing Matriderm grafted skin to normal skin using Cutometer, Matriderm proved valuable in restoring skin elasticity and the skin barrier.

• Applied Chemistry for Engineering
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• v.23 no.5
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• pp.445-449
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• 2012

The activation process of the membrane-electrode assembly (MEA) is important for the mass production of the polymer electrolyte membrane fuel cell. The conventional activation process for the MEA requires excessive time and hydrogen gas and it might become the barrier for the commercialization of the fuel cell. The conventional activation process is based on hydrolysis of ion conducting membrane. In the study, we suggest the cyclic voltammetry (CV) technique as an on-line activation process and the CV activation process consists of two steps : 1) the humidification of the polymer electrolyte membrane and the electrode with 100% RH humidified nitrogen ($N_{2}$) gas, and 2) the removal step of the oxide layer on the surface of the Pt catalyst with CV cycling. The cycling reduces the activation time of the MEA by 2.5 h and use of hydrogen gas by 1/4.

• Journal of The Korean Society of Agricultural Engineers
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• v.46 no.7
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• pp.35-44
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• 2004

In this study, a ventilation model was developed to determine a ventilation rate for the balance of heat, moisture and $CO_{2}$ in a mushroom house. Internal and external temperature, relative humidity and $CO_{2}$ concentration were measured and used to validate the ventilation model. The effects of various environmental factors on physiological responses of mushroom were also investigated. The verified model was simulated under the observed ventilation rates with a difference of$ 0.001{\~}0.065\;m^{3}{\cdot}S^{-1}$ (relative error of $0.3{\~}18.9\%$) when external temperature varied 22.5 to $24.8^{circ}C$ and average ventilation rates was $0.35m^{3}{\cdot}S^{-1}$. The optimal conditions for mushroom growth (internal temperature $22 ^{circ}C$, relative humidity $80\%$, $CO_{2}$ concentration 1,000 ppm) were used for the model application with external temperature, relative humidity and $CO_{2}$ concentration of $27.5{\~}33.5^{circ}C$, $60\%$, and 355 ppm, respectively. Thermal balance was a important factor for an optimum ventilation up to the external temperature of $32^{circ}C$, while $CO_{2}$ concentration balance was more important over $32^{circ}C$. This suggests that humidification for moisture balance is required to maintain temperature and $CO_{2}$ concentration at an optimal level by ventilation in a mushroom house.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.4
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• pp.13-18
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• 2016

Humidifiers are used to control indoor humidity. Element-type humidifiers have the advantages of simple structure and low energy consumption, and Japanese products have been widely used for the humidifying elements. In this study, a new humidifying element made of cellulose and PET was developed, and the performance was compared with that of a Japanese element. The mass transfer rates and pressure drops were measured for an element installed at the entrance of a suction-type wind tunnel. The humidification efficiency of the new element was 2 to 4% greater and the pressure drop was 23 to 32% smaller compared to the Japanese element. The mass transfer effectiveness ($j_m/f$) of the new element is also 5 to 28% higher. However, the water absorption capacity was smaller than that of the Japanese element, meaning further development is needed.