• Tissue Engineering and Regenerative Medicine
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• 제15권6호
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• pp.735-750
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• 2018

BACKGROUND: The major challenge of tissue engineering is to develop constructions with suitable properties which would mimic the natural extracellular matrix to induce the proliferation and differentiation of cells. Poly(${\varepsilon}$-caprolactone)-poly(ethylene glycol)-poly(${\varepsilon}$-caprolactone) (PCL-PEG-PCL, PCEC), chitosan (CS), nano-silica ($n-SiO_2$) and nano-hydroxyapatite (n-HA) are biomaterials successfully applied for the preparation of 3D structures appropriate for tissue engineering. METHODS: We evaluated the effect of n-HA and $n-SiO_2$ incorporated PCEC-CS nanofibers on physical properties and osteogenic differentiation of human dental pulp stem cells (hDPSCs). Fourier transform infrared spectroscopy, field emission scanning electron microscope, transmission electron microscope, thermogravimetric analysis, contact angle and mechanical test were applied to evaluate the physicochemical properties of nanofibers. Cell adhesion and proliferation of hDPSCs and their osteoblastic differentiation on nanofibers were assessed using MTT assay, DAPI staining, alizarin red S staining, and QRT-PCR assay. RESULTS: All the samples demonstrated bead-less morphologies with an average diameter in the range of 190-260 nm. The mechanical test studies showed that scaffolds incorporated with n-HA had a higher tensile strength than ones incorporated with $n-SiO_2$. While the hydrophilicity of $n-SiO_2$ incorporated PCEC-CS nanofibers was higher than that of samples enriched with n-HA. Cell adhesion and proliferation studies showed that n-HA incorporated nanofibers were slightly superior to $n-SiO_2$ incorporated ones. Alizarin red S staining and QRT-PCR analysis confirmed the osteogenic differentiation of hDPSCs on PCEC-CS nanofibers incorporated with n-HA and $n-SiO_2$. CONCLUSION: Compared to other groups, PCEC-CS nanofibers incorporated with 15 wt% n-HA were able to support more cell adhesion and differentiation, thus are better candidates for bone tissue engineering applications.

• 한국철학논집
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• 제30호
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• pp.7-36
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• 2010

조선조 사림의 영수이자 한국 도학의 태산북두로 평가되는 조광조는 지치주의라는 순수이념으로 절대적인 도덕정치를 펼치고자 하였던 인물이다. 그런 점에서 그는 철저한 이성주의자였다. 그럼에도 불구하고 그는 당시 현실 정치에 임하여서는 군신간에 부자(父子)의 예로써 소통하여야 함을 특별히 강조하였다. 그것은 인간관계의 격의를 해체함으로써 객관적, 이성적 존재보다는 주관적, 정서적 존재로서 친밀한 소통의 중요성을 역설한 것이다. 또 스스로 애군(愛君), 우국(憂國)을 애부(愛父), 우가(憂家)의 감정으로써 실천하는 모습을 몸소 보여 주었다. 이러한 점은 그가 지향한 지치적 순수정치는 인간의 감성이 통하는 세상임을 의미한다. 또한 그는 기묘사화라는 정치적 폭거를 계기로 깊은 인간적 고뇌와 슬픔을 절감하였다. 그 과정에서 그는 견디지 못하는 아픔을 자연스런 감정 표현으로 숨기지 않았는데, 특히 능주에서 유배 이후의 생활과 종명 과정에서는 매우 인간적인 감정을 가감 없이 드러낸 바 있다. 그러나 그의 슬픔은 단지 슬픔으로 끝나지 않았고 새로운 희망으로 승화되어 후세 사람들의 마음에 길이 살아 있게 되었다. 인간의 성정(性情) 문제에서 도학 [성리학]은 정보다는 성을 강조하지만, 이성보다는 감정이나 정서를 중심으로 도학자의 삶을 살피는 것은 한 인간의 실존적 내면을 살피는 측면에서 의미 있는 일이다.

• 대한한의학원전학회지
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• 제7권
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• pp.198-231
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• 1994

Up to now, after I had examined the relation between the origin of Fung(風) and Gi(氣) and the mean of Fung in medical science, I obtained the conclusion being as follows. The first, Fung(風) means a flux of Gi(氣) and Gi shows the process by virtue of the form of Fung, namely, Fung means motion of Gi. In other words, it is flow of power. Accordingly, the process of all power can give a name Fung. The second, Samul(事物) ceaselessly interchange with the external world to sustain the existence and life of themselves. And they make a adequate confrontation against the pressure of the outside. This the motive power of life action(生命活動) is Gi and shows its the process on the strength of Fung. The third, Samul(事物) incessantly releases power which it has to the outside. Power released to the outside forms the territory of the established power in the environment of them and keep up their substance(實體) in the space time(時空). It can be name Fung because the field(場) of this power incessantly flows. The fourth, man operates life on the ground of the creation of his own vigor(生氣) for himself as the life body(生命體) of the independence and self-support. The occurence of this vigor and the adjustment process(調節作用) is supervised by Gan(肝). That is to say, Gan plays a role to regulate and manage the process of Fung or the action of vigor with Fung-Zang(風臟). The fifth, because the Gi-Gi adjustment process(氣機調節作用) of Gan is the same as the process of Fung, Fung that operates the cause of a disease is attributed to the disharmony of the process of the human body Gi-Gi. Therefore, the generating pathological change is attributed to the extraordinary of the function by the incongruity of Gi-Gi(氣機) or the disorder of the direct motion of Gi-Hyul(氣血). Because the incongruity of this Gi-Gi of the human body gives rise to the abnormal of Zung-Gi(正氣) in the human body properly cannot cope with the invasion of 'Oi-Sa(外邪). Furthermore, Fung serves as the mediation body of the invasion of other Sa-Gi(邪氣) because of its dynamics, By virtue of this reason, Fung is named the head of all disease. And because the incongruity of the Gi-Gi has each other form according to Zang-Bu(臟腑), Kyung-Lak(經絡), and a region, the symptoms of a disease appear differently in line with them as well. The sixth, Fung-byung(風病) is approximately separated Zung-Fung(中風) and Fung-byung(猍義의 風病). Zung-fung and Fung-byung is to be attributed to the major invasion of each Jung-gi and Fung-sa(正氣와 風邪). But these two kinds stir up the problem to the direct motion of Gi-hyul(氣血) and the harmony of Gi-Gi in the human body. When one cures it, therefore, Zung-fung has to rectify Gi-Gi and the circulation of Gi-hyul on the basis of the supplement of Jung-gi(正氣) and Fung-byung must make the harmony of Gi-Gi with the Gu-fung(驅風). -Go-gi(調氣), Sun-Gi(順氣). Hang-Gi(行氣) - All existing living things as well as man maintain life on the ground of the pertinent harmony between the soul(精神) and the body(肉體). As soon as the harmony falls down, simultaneously life disappears as well. And Fung which means the outside process between Gi(氣) and Gi(氣) makes the action of their life cooperative and unified, Accordingy, the understanding of Fung, first, has to start wi th the whole thought that not only all Samul(事物) but also the soul and the body are one.

• 한국실내디자인학회논문집
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• 제21권1호
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• pp.240-247
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• 2012

Healing Environment is to cure the user as a whole by considering his social, psychological aspect, beyond the functional aspect of treatment. Various design elements of healing space have been developed so far, but they were mostly described with same rank. Even though every element is significant, facilities such as nursing homes tends to run with low budget, and they can't fulfill them all at the same time. It is important to find the sequence between design elements. The purpose of this study is to reorganize the design principles of healing environment by Maslow's hierarchy of needs(Physiological needs, Safety needs, Love/Affilitation needs, Self-Esteem needs and Self-Actualization needs), and analyze elderly nursing homes and examine the framework itself by application. Research method was consist of literature review on healing space design elements and hierarchy of needs, reconstruction of design elements with hierarchy, and application on 5 Korean nursing home cases. As the result, Maslow's hierarchy of needs and design elements were linked with good balance. Analysis of 5 nursing homes revealed that lower needs were short of environmental support compared to higher needs. Especially design elements related to Physiological needs should be improved. Also, new framework had strength in not only providing gasps on current situation in detail, but also suggesting elements for improvement with hierarchy and sequence. Through this research healing environment design elements and human needs were linked. Nursing home is the last environment for the elderly, which should help to heal their body and mind and also support them to accomplish self-actualization.

• 제어로봇시스템학회논문지
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• 제21권6호
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• pp.503-509
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• 2015

In this paper, we designed and tested an ankle joint mechanism for a gait rehabilitation robot. Gait rehabilitation programs are designed to improve the natural leg motion of patients who have lost their walking capabilities by accident or disease. Strengthening the muscles of the lower-limbs and stimulation of the nervous system corresponding to walking helps patients to walk again using gait assistive devices. It is an obvious requirement that the rehabilitation system's motion should be similar to and as natural as the normal gait. However, the system being used for gait rehabilitation does not pay much attention to ankle joints, which play an important role in correct walking as the motion of the ankle should reflect the movement of the center of gravity (COG) of the body. Consequently, we have designed an ankle mechanism that ensures the safety of the patient as well as efficient gait training. Also, even patients with low leg muscle strength are able to operate the ankle joint due to the direct-drive mechanism without a reducer. This safety feature prevents any possible adverse load on the human ankle. The additional degree of freedom for the roll motion achieves a gait pattern which is similar to the normal gait and with a greater degree of comfort.

• 한국전산구조공학회논문집
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• 제28권2호
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• pp.207-212
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• 2015

사회기반시설물인 교량은 인적/물적 자원의 신속하고 원활한 이동을 위해 지장물을 극복하도록 설계/시공되는 구조물이다. 그러므로 교량의 교축방향으로 배열되는 교각의 형상과 규모는 지형의 제약을 받을 수밖에 없다. 이러한 교각의 형상과 규모는 지진하중의 전달경로를 결정하는 연결부분 배열과 함께 연결부분과 교각에 발생하는 작용력을 좌우하게 된다. 이 연구에서는 강재받침과 철근콘크리트 기둥을 연결부분과 교각으로 하는 일반교량을 대상으로 교각 및 강재받침 배열이 다른 해석모델을 설정하여 지진해석을 수행하였다. 해석결과로 구한 교각기둥과 강재받침의 강도/작용력 비로부터 각 해석모델의 연성파괴메카니즘을 구성하고 연결부분 및 교각 배열이 일반교량의 내진성능에 미치는 영향을 연성파괴메카니즘 구성 측면에서 제시하였다.

• 한국학교보건학회지
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• 제8권2호
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• pp.293-303
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• 1995

Health has occupied a position of importance in the human history, whether it be in the East or in the West, and it is a subject in which people have been constantly interested. The concept of health has changed continuously as the society has developed, industrialized and become more structured. The perception of health concept can be an esential factor which is to determine the health behaviors. This study is a descriptive inquiry done to identity high school students' perception of health and what they do as health behaviors. The subject consisted of 503 voctional high school seniors, 129 boys and 374 girls, from a school located in An-san Si, kyong-gi Do. The instruments used for this study were open-ended questionnaires and data were collected by having the students fill out the questionnaires which took 10 minutes, in their first class, April 6, 1995. The collected materials were classified and recorded on the cards according to each question using the terms which students had written. After putting statements which had common meanings together, the representative categories were labelled. The results obtained are as follows. 1. Categorizing and labelling of health concepts What high school students descripted as health concepts were classified as the absence of illness, physical comfort, strong physical strength and physique, not having a deformity, resisting power, self control mental-rest(or psychological comfort), wholesome ideas, self-control, harmony in body and in mind, maintenace of daily life, pleasant life, good friends, peaceful family life and realizing objectives. 2. Categorizing and labelling of health behaviors These were classified as preventive life, good dietary habits and regimen, maintenance of clean body, exercises, preventing obesity, rest, environmental balance or control of environment, limit one's tastes, making use of leisure, peaceful mind, sound thought and regular living habits. The result indicates that the health concepts were positive and included not only absence of illness but also harmony in body and in mind and pleasant life; health behaviors which had high frequency were good dietary habits and regimen, exercises and sound thought. It is hoped that these findings well serve as practical references for teachers when they counsel with, and provide the students with guidance programs which include health care.

• 한국의류산업학회지
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• 제19권6호
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• pp.759-767
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• 2017

This study investigates the improvement of domestic compression stockings by comparing and analyzing the characteristics of materials and fabrics of medical compression stockings developed in Korea and domestic imported compression stockings. Among imported compression stockings currently available in Korea, three brands with high sales rates are selected by countries (USA, Italy, and Germany) to measure the physical and mechanical properties of the material. Medical compression stockings to be analyzed were selected as M size pantyhose included in 20-30mmHg. As a result, the tensile elongation of medical compression stockings selected in this study was the highest in Korean products in the ankle, while the highest in the US was in the thigh, and the elasticity of Italian products was low. The recovery rate of the kidneys was similar for all four ankles. The ankle weight was the highest except for Korean products that showed the highest weight of the thigh and difference from products of other countries. US product also showed high shape stability due to high recovery of tensile strength from high value RT. Italian products showed low banding and shear values; however, shape stability was poor with good drapeability. In Germany, LT and RT values were low, but clothing comfort was considered excellent. In Korea, LT and RT values, banding and shear characteristics were high, and drapeability was poor. Stiffness was good, but recoverability was excellent.

• Advanced Composite Materials
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• 제18권4호
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• pp.351-364
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• 2009

The thermal stability and elevated temperature mechanical properties of $SiC_P$/Al-11.7Fe-1.3V-1.7Si (Al-11.7Fe-1.3V-1.7Si reinforced with SiC particulates) composites sheets prepared by spray deposition (SD) $\rightarrow$ hot pressing $\rightarrow$ rolling process were investigated. The experimental results showed that the composite possessed high ${\sigma}_b$ (elevated temperature tensile strength), for instance, ${\sigma}_b$ was 315.8 MPa, which was tested at $315^{\circ}C$, meanwhile the figure was 232.6 MPa tested at $400^{\circ}C$, and the elongations were 2.5% and 1.4%, respectively. Furthermore, the composite sheets exhibited excellent thermal stability: the hardness showed no significant decline after annealing at $550^{\circ}C$ for 200 h or at $600^{\circ}C$ for 10 h. The good elevated temperature mechanical properties and excellent thermal stability should mainly be attributed to the formation of spherical ${\alpha}-Al_{12}(Fe,\;V)_3Si$ dispersed phase particulates in the aluminum matrix. Furthermore, the addition of SiC particles into the alloy is another important factor, which the following properties are responsible for. The resultant Si of the reaction between Al matrix and SiC particles diffused into Al matrix can stabilize ${\alpha}-Al_{12}(Fe,\;V)_3Si$ dispersed phase; in addition, the interface (Si layer) improved the wettability of Al/$SiC_P$, hence, elevated the bonding between them. Furthermore, the fine $Al_4C_3$ phase also strengthened the matrix as a dispersion-strengthened phase. Meanwhile, load is transferred from Al matrix to SiC particles, which increased the cooling rate of the melt droplets and improved the solution strengthening and dispersion strengthening.

• 환경정책연구
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• 제12권4호
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• pp.23-44
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• 2013

기후변화에 효율적으로 대응하기 위해서는 막대한 예산이 소요되는 적응대책에 대한 우선순위를 선정하고 이에 따라 시행하는 일이 매우 중요하다. 본 연구의 목적은 적응대책의 우선순위 평가 방법론을 분석해 현재 가용한 정보의 범위에서 기후변화의 특수성을 반영해 적용 가능한 우선순위 평가 방법론을 제안하는 것이다. 우선순위 결정을 위한 의사결정 방법론은 다기준 분석 등의 정성적 분석법과 비용편익 분석 등의 정량적 평가 방법론이 있다. 각 방법론별로 서로 장점과 단점이 있으며 필요 자료의 수준도 상이하다. 정책평가를 위한 지표는 정책의 효율성, 경제성, 정치성 등을 평가하는 많은 지표가 존재한다. 본 논문에서는 일반 정책평가 지표와 기후변화의 특수성을 고려해 기후변화 적응대책의 우선순위 평가 지표로 크게 기후변화 위험성, 정책성, 효율성을 선정하였다. 기후변화 위험성의 세부 지표로는 피해발생시점, 피해발생 가능성, 피해 강도가 포함되며, 효율성으로는 경제적 효율성, 부수효과, 파급효과로 대표될 수 있다. 정책성의 평가 지표는 형평성, 기존 정책과의 부합성, 민주성으로 구성된다.