• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.15 no.10 s.103
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• pp.1160-1168
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• 2005

Floor impact noise isolation performance of reinforced concrete floors was investigated through new measurement method using impact bail. Strong impact force in Bow frequency band below 63 Hz of bang machine is not similar to human impact source and causes some problem in evaluating heavy-weight Impact noise but heavy-weight impact noise measurement and evaluation using impact ball which is very similar to human impact is more reliable than bang machine. Correction value on the background noise and sensitivity of residents should be considered on the floor impact noise evaluation classes.

• Journal of Advanced Navigation Technology
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• v.9 no.2
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• pp.170-176
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• 2005

In this paper, we proposed watermarking algorithm based on wavelet transform. Discrete wavelet transform is involved to calculate additive energy strength. Considering imperceptibility, after computing contrast and texture sensitivity in gray-level image, we inserted watermark with variable weight due to the feature of coefficient block. Consequently, applying human visual system, the experimental results showed that the proposed algorithm satisfied the properties of robustness and imperceptibility that are the major conditions of watermarking.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1996.10a
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• pp.338-344
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• 1996

In this paper, a semi-active suspension adapting to road variation which also considers the frequency snesitivity of human is proposed. First, a road adapting controller composed of system identification and LQG control is designed. Using the extended least squares method, the road property is estimated by system identification as it varies, and the LQG controller considering the estimated road property and the frequency sensitivity of human is designed. Next, the semi-active suspension is made, which tracks the performance of the active suspension with the road adapting controller. Through numerical simulation, the performance of the proposed semi-active suspension is compared with that of a non-adaptive semi-active suspension with frequency-shaped performance index. As a result, we see that the road adapting semi-active suspension has better performance.

• Nuclear Engineering and Technology
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• v.51 no.6
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• pp.1561-1574
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• 2019

A standard form of six stylized human intrusion scenarios for a near-surface disposal facility (e.g. the planned Korean repository, Gyeongju Phase II) is proposed through re-categorization of totally thirty-one past cases reported in public literature. A reference assessment framework for inadvertent human intrusion is newly developed using GENII Version 2 conforming to the ICRP Publication 60 and thereafter. Calculated dose from the assessment framework is verified by comparing with hand calculation results for simplified model equations independently derived. Results from GENII Version 2 and 1.485 show inevitable differences, which is mainly attributed to the difference in the external dose assessment model. If intake dose coefficients in GENII Version 1.485 are modified, the difference can be reduced but still exist to an extent. Through deterministic and probabilistic sensitivity analysis, most affecting four parameters are derived and uncertainties of the parameters are quantified. It is expected that the reference assessment framework together with representative stylized scenarios can be used to do a human intrusion impact assessment for a specific repository using site-specific information. Especially, the past practice of human intrusion impact assessment using GENII Version 1.485 with or without modification may be replaced with the new assessment framework developed in this study.

• Journal of Microbiology and Biotechnology
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• v.26 no.2
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• pp.394-401
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• 2016

Recently, the clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein 9 (CRISPR/Cas9) system, a genome editing technology, was shown to be versatile in treating several antibiotic-resistant bacteria. In the present study, we applied the CRISPR/Cas9 technology to kill extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli. ESBL bacteria are mostly multidrug resistant (MDR), and have plasmid-mediated antibiotic resistance genes that can be easily transferred to other members of the bacterial community by horizontal gene transfer. To restore sensitivity to antibiotics in these bacteria, we searched for a CRISPR/Cas9 target sequence that was conserved among >1,000 ESBL mutants. There was only one target sequence for each TEM- and SHV-type ESBL, with each of these sequences found in ~200 ESBL strains of each type. Furthermore, we showed that these target sequences can be exploited to re-sensitize MDR cells in which resistance is mediated by genes that are not the target of the CRISPR/Cas9 system, but by genes that are present on the same plasmid as target genes. We believe our Re-Sensitization to Antibiotics from Resistance (ReSAFR) technology, which enhances the practical value of the CRISPR/Cas9 system, will be an effective method of treatment against plasmid-carrying MDR bacteria.

• Journal of Korea Water Resources Association
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• v.50 no.3
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• pp.139-153
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• 2017

The variation in runoff due to global climate change and urbanization should be identified quantitatively because these two factors have been significantly accelerated during the last three decades in South Korea. However, only a few research to analyze the impacts due to two factors over different time scales can be found. Therefore, in this study, the hydrological model based approach and the hydrological sensitivity approach were used to separate relative impacts by two factors on monthly, seasonal, and annual time scales at the Soyang River upper basin and the Seom River basin in South Korea. The 3 techniques such as the double mass curve method, the Pettitt's test, and the BCP analysis were performed to detect change point occurred by abrupt change in the collected observed runoff. After detection of change ponts, SWAT models calibrated on the natural periods were used to calculate the changes due to human activities. Also, 6 Budyko based methods were auxiliary to verify the results from hydrological based approach.

• 한국전산유체공학회:학술대회논문집
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• 2004.10a
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• pp.131-136
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• 2004

Thermal control of satellite propellant tank is achieved by patch heaters enabled by thermostat's behavior. It is important to attach the thermostat on the appropriate position of the propellant tank. However its position cannot be given with exact numerics because tank is spherical. Actually the position for thermostat is designated in relevant drawing approximately, therby, the engineer practices depending on his own experience and intuition. The sensitivity analysis for the position of thermostat is performed such that the influence on the thermal behavior and control of tank is examined quantatively. When assembling tank module, the reasonable performance on the thermal control is believed with possible human errors if the uncertainty in the position of thermostat is not quite large.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2004.05b
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• pp.454-458
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• 2004

A new algorithm for the rate control of videos considering the sensitivity of the human visual system is presented. The method adopts the three-step structure of MPEG2 TM5 rate control, and a new measure of macroblock activity based on spatio-temporal sensitivity is introduced for the adaptive quantization. Experimental results show that the spatio-temporal activity measure outperforms the spatial activity of TM5 in picture quality.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.39 no.2
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• pp.147-152
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• 2015

We designed, fabricated, and tested the capacitive microsensors for skin piloerection monitoring. The performance of the skin piloerection monitoring sensor was characterized using the artificial bump, representing human skin goosebump; thus, resulting in the sensitivity of $-0.00252%/{\mu}m$ and the nonlinearity of 25.9 % for the artificial goosebump deformation in the range of $0{\sim}326{\mu}m$. We also verified two successive human skin piloerection having 3.5 s duration on the subject's dorsal forearms, thus resulting in the capacitance change of -6.2 fF and -9.2 fF compared to the initial condition, corresponding to the piloerection intensity of $145{\mu}m$ and $194{\mu}m$, respectively. It was demonstrated experimentally that the proposed sensor is capable to measure the human skin piloerection objectively and quantitatively, thereby suggesting the quantitative evaluation method of the qualitative human emotional state for cognitive human-machine interfaces applications.

• BMB Reports
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• v.46 no.3
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• pp.169-174
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• 2013

The human $B_{12}$ trafficking chaperone hCblC is well conserved in mammals and non-mammalian eukaryotes. However, the C-terminal ~40 amino acids of hCblC vary significantly and are predicted to be deleted by alternative splicing of the encoding gene. In this study, we examined the thermostability of the bovine CblC truncated at the C-terminal variable region (t-bCblC) and its regulation by glutathione. t-bCblC is highly thermolabile ($T_m={\sim}42^{\circ}C$) similar to the full-length protein (f-bCblC). However, t-bCblC is stabilized to a greater extent than f-bCblC by binding of reduced glutathione (GSH) with increased sensitivity to GSH. In addition, binding of oxidized glutathione (GSSG) destabilizes t-bCblC to a greater extent and with increased sensitivity as compared to f-bCblC. These results indicate that t-bCblC is a more sensitive form to be regulated by glutathione than the full-length form of the protein.