• Neonatal Medicine
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• 제18권2호
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• pp.165-176
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• 2011

The pathologic hallmark of new bronchopulmonary dysplasia (BPD) is an arrest in alveolarization and vascular development. Alveoli are the fully mature gas-exchange units and alveolarization denotes the process through which the developing lung attains its fully mature structure. In human, alveolarization is mainly a postnatal event and begins in utero around 35 postmenstrual weeks and continues to 2 postnatal years. Beginning of respiration with very immature lungs as a result of preterm delivery renders the immature lung to be exposed to various injuries such as mechanical stretch, hyperoxia, infection/inflammation and leads to a disruption of normal alveolarization process, which is a main pathologic finding of BPD. Better understanding of the control mechanisms of normal alveolarization process should help us to figure out the pathophysiology of BPD and discover effective preventive or therapeutic measures for BPD. In this review, the pathologic evolution of BPD from 'old' to 'new' BPD, the detailed mechanisms of normal alveolarization, and the factors that disrupt normal alveolarization will be discussed.

• 한국IT서비스학회지
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• 제11권2호
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• pp.185-196
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• 2012

The rapid evolution of ICT industry brings not only new services or products but also changes from common individual life to whole human society. Coping with these situations and survival, companies cannot help regarding R&D as the most important thing. So, discovering R&D projects which are suitable for the alternation is a big issue for many companies. To resolve the issue, KT has adopted Innovative Management Methodology developed by Strategos, which is co-founded by Gary Harmel. This paper describes this Innovative Management Methodology tailored to KT R&D. The methodology consists of five phases : focusing discovery, discovery, ideas/domains, domain elaboration & aiming point and R&D project proposal. Also, it shows some interim findings that came from the Innovative Management Process. Finally, the future plan for elaborating the methodology itself and generating new R&D projects is suggested.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1995년도 추계학술대회 논문집
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• pp.894-897
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• 1995

This paper focuses on self-organization of fuzzy rules for performance management of computer communication networks serving manufacturing systems. The performance management aims to improve the network performance in handling various types of messages by on-line adjustment of protocol parameters. The principle of fuzzy logic has been used in representing the knowledge of human expert on the performance management and in deriving management decisions. In this paper, we present applications of genetic algorithm, simulated annealing, and evolution strategies to find a better set of rules for various network conditions. The efficacy of this self-organization is demonstrated by discrete simulation of an IEEE 802.4 network.

• 한국동물번식학회:학술대회논문집
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• 한국동물번식학회 2002년도 춘계학술발표대회 발표논문초록집
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• pp.5-5
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• 2002

Nucleoside diphosphate kinases (NDPKs) are conserved through evolution and have been shown to be involved in various biological phenomena. By functional screening in yeast, we identified a new member of the NDPK family, ㎚23-M5, which encodes a 211-amino acid protein with 86% identify to the human homolog, ㎚23-H5. Northern blot analysis reveals that ㎚23-M5 encodes two transcripts of 0.8 and 0.7 kb, which are highly and specifically expressed in adult testis. Reverse transcriptase polymerase chain reaction analysis shows that nm23-M5 first appears in pachytene spermatocytes and increase chain reaction in abundance through subsequent stages. (omitted)

• 한국실내디자인학회논문집
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• 제14권5호
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• pp.3-9
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• 2005

Territoriality and privacy are known to be basic human instincts that have made today's cultural evolution possible. However there are also cultural differences in the expressions and meanings of territorial and privacy behaviors. Currently with the emerge of non-territorial workplaces office workers are deprived from what used to be their territory and force to share with co-workers leading confusion and stress. Therefore many research has be conducted on territorial issues but unfortunately little is known on Korean cultural concept of territoriality and privacy. Eyen though Korean society has been rapidly westernized during the 20th century, traditional culture still is a major influence on Korean's concept and use of space. This study explores and investigates the concept of territoriality and privacy and how they are expressed in traditional Korean housing focused on high level society between 17th and 19th century. Thus hope make a small contribution in designing unique and culture based interior spaces.

• 지식경영연구
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• 제1권1호
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• pp.19-46
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• 2000

Today, knowledge is considered the most strategically important resource. As research in knowledge management advances, it ought to review and categorize the already published literatures on knowledge management in the area of business strategy, accounting/finance, human resource management and management information technology. To identify the knowledge management research trend, we analyze 168 articles published in prominent academic journal during last two decades. This paper develops three stages model for knowledge management research: observation, initiation and evolution stage. Also, we classify the given researches according to the three criteria of contents, related academic area and applied research method.

• Computers and Concrete
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• 제18권1호
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• pp.69-97
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• 2016

Performance-based remaining life assessment of reinforced concrete bridge girders, subject to chloride-induced corrosion of reinforcement, is addressed in this paper. Towards this, a methodology that takes into consideration the human judgmental aspects in expert decision making regarding condition state assessment is proposed. The condition of the bridge girder is specified by the assignment of a condition state from a set of predefined condition states, considering both serviceability- and ultimate- limit states, and, the performance of the bridge girder is described using performability measure. A non-homogeneous Markov chain is used for modelling the stochastic evolution of condition state of the bridge girder with time. The thinking process of the expert in condition state assessment is modelled within a probabilistic framework using Brunswikian theory and probabilistic mental models. The remaining life is determined as the time over which the performance of the girder is above the required performance level. The usefulness of the methodology is illustrated through the remaining life assessment of a reinforced concrete T-beam bridge girder.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1997년도 추계학술대회 논문집
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• pp.556-559
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• 1997

This paper describes the development process of mosquito trap with the effect of air cleaning by using the substance-field analysis and evolution pattern of systems in the theory of inventive problem solving (TRIZ). By the concept of standard solution about introducing S3 substance, modification of S1 (human) and S2 (mosquito) between first substance SI and second substance S2 with harmful effect, we got the concept of the mosquito trap with mosquito attractants instead of mosquito reluctants such as mosquito stick coil and skin medicine w~th bad and toxic smell. The number of mosquitos traped by one trap near cattle shed per one n~ght in summer, was over 10 thousands with some effects of air cleaning.

• Journal of Dairy Science and Biotechnology
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• 제25권2호
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• pp.21-28
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• 2007

Recently, the field of microbiology has been transformed by huge increasing number of publicly available whole-genome sequences. This sequence information has significantly enhanced our understanding of the physiology, genetics, and evolutionary development of bacteria. Among the gastrointestinal microorganisms, bifidobacteria represent the most important human commensals because of their contribution to maintaining a balanced gastrointestinal tract microbiota. In recent years bifidobacteria have drawn much scientific attention due to their use as live bacteria in numerous food products with various health-related claims. For this reason, these bacteria constitute a growing area of interest with respect to genomics, molecular biology, and genetics. Recent genome sequencing of a number of bifidobacterial species has allowed access to the complete genetic make-up of these bacteria. This review will focus how genomic data has allowed us to understand bifidobacterial evolution, while also revealing genetic functions that explains their presence in the particular ecological environment of the gastrointestinal tract.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제5권5호
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• pp.938-958
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• 2011

Ubiquitous web services have been expanding in various business areas with the evolution of wireless Internet technologies, accessible and usable with a variety of mobile Internet devices such as smart phones. Ubiquitous mobile-web information services can be evaluated for accessibility and usability with the mobile Internet devices interacting with mobile-web information servers. In human mobile-web activity, a web server could be a unified center for mobile-web interaction services as well as for real-time estimation and analysis of mobile-web interaction sessions. We present a real-time estimation and analysis scheme for time-based accessibility and usability in ubiquitous mobile-web services. With real-time estimation/analysis of sessions in a mobile-web server, we estimated the time-based accessibility and usability for comparison between different web services as well as for applications in mobile cloud computing services. We present empirical results based on the implementation of the real-time estimation/analysis scheme.