• Journal of The Korean Association For Science Education
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• v.29 no.8
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• pp.990-1010
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• 2009

To derive brain-based evolutionary educational principles, this study examined the studies on the structural and functional characteristics of human brain, the biological evolution occurring between- and within-organism, and the evolutionary attributes embedded in science itself and individual scientist's scientific activities. On the basis of the core characteristics of human brain and the framework of universal Darwinism or universal selectionism consisted of generation-test-retention (g-t-r) processes, a Model of Brain-based Evolutionary Scientific Teaching for Learning (BEST-L) was developed. The model consists of three components, three steps, and assessment part. The three components are the affective (A), behavioral (B), and cognitive (C) components. Each component consists of three steps of Diversifying $\rightarrow$ Emulating (Executing, Estimating, Evaluating) $\rightarrow$ Furthering (ABC-DEF). The model is 'brain-based' in the aspect of consecutive incorporation of the affective component which is based on limbic system of human brain associated with emotions, the behavioral component which is associated with the occipital lobes performing visual processing, temporal lobes performing functions of language generation and understanding, and parietal lobes, which receive and process sensory information and execute motor activities of the body, and the cognitive component which is based on the prefrontal lobes involved in thinking, planning, judging, and problem solving. On the other hand, the model is 'evolutionary' in the aspect of proceeding according to the processes of the diversifying step to generate variants in each component, the emulating step to test and select useful or valuable things among the variants, and the furthering step to extend or apply the selected things. For three components of ABC, to reflect the importance of emotional factors as a starting point in scientific activity as well as the dominant role of limbic system relative to cortex of brain, the model emphasizes the DARWIN (Driving Affective Realm for Whole Intellectual Network) approach.

• Korean Journal of Heritage: History & Science
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• v.53 no.1
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• pp.126-149
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• 2020

Considering significant words that stand for the history of Paleolithic in North Korea, these can be summarized for each decade since the 1960s. The 1960s ought to be when the earliest discovery of a Paleolithic site was made by Korean hands. The 1970s might be the earliest period for textbooks being published that were geared towards increasing general understanding of the Paleolithic era in the Korean peninsula. The 1980s can be summarized as a period of reissued Paleolithic articles from a newly introduced archaeological journal. The 1990s witnessed efforts to formulate nationalistic interpretations about the Paleolithic period in Korea. The 2000s then synthesized several of these aspects of Paleolithic studies. Gulpori, the Paleolithic site that was discovered in the 1960s, holds significance not just because of the discovery itself, but because of its prompt acceptance by North Korean academic authorities. The publications that covered general understanding of Paleolithic archaeology such as Joseon Gogohag Gaeyo, Joseon-ui Guseoggisidae, and Joseonjeonsa: Wonsipyeon in the 1970s hold immense significance themselves, as they demonstrate contemporary achievements. Reintroduction of the archaeological Journal, Joseongogoyeongu in 1986, is the beacon of alleviation of conspicuous effect to the academic sector. During the 1990s, a new emphasis on nationalism influenced Paleolithic studies. In the 2000s, the formally constructed elements of Paleolithic research such as Paleolithic chronology, social evolution, lithic assemblage, Quaternary studies, and human evolution were consistently refined. Metaphorically speaking, these parts are like a polygonal structure. As is the case with a polygonal structure, these research aspects are united and work together. Each part affects the others. Although the content of each research aspect has been altered by either academic growth or sociopolitical agenda, the fundamental part of the polygonal structure is not likely to be changed. The structure is solid enough to continue to serve the purposes of North Korean Paleolithic studies. North Korean Paleolithic archaeology seems to be a juxtaposition; some parts are easily changed while others are not. In order to ascertain these, not only the academic but also the sociopolitical context should be followed.

• Journal of Life Science
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• v.18 no.12
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• pp.1733-1738
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• 2008

SLC6A18, one of the neurotransmitters, was reported the possible relationship to hypertension, and it contained eight blocks of minisatellites. In this study, SLC6A18-MS5 sequence which showed the highest heterozygosity among seven minisatellites was analyzed using the Transfac software, the putative binding sites for the transcription factor Pax4 and HNF4 were discovered as a result. The HNF4 is involved in the diabetes pathway and suggested the relationship to hypertension. Thus, we investigated the putative functional significance of allelic variation in this minisatellites with respect to susceptibility for hypertension. To address this possibility, we analyzed genomic DNA from the blood of 301 hypertension-free controls and 184 cases with hypertension. A statistically significant association was not identified between the allelic distribution of SLC6A18-MS5 and occurrence of hypertension. We then examined the meiotic segregation of SLC6A18-MS5 and it was transmitted following Mendelian inheritance. Therefore, this locus could be useful markers for paternity mapping and DNA fingerprinting. Moreover, we undertook a comprehensive analysis of the genomic sequence to address the evolutionary events of these variable repeats. SLC6A18 minisatellites regions are only conserved in human and primates. This result suggestedthat intronic minisatellites analysis is powerful evolution marker for the non-coding regions in primates and can provide a great insight to the molecular evolution of repeated region in primates.

• Journal of the Society of Disaster Information
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• v.8 no.1
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• pp.1-9
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• 2012

Informatization of society through the computer and the Internet, because large amounts of information production and exchange and new way of communicating is born. Passive way past the one-sided information flows actively interact to evolve in a manner of information producers and information consumers distinction and personal relationships that enhance the online Social Networking Service (SNS) has developed into the social structure of. Thus, the spread of information work closely with the social network structure spark social conflict may act as a factor, and systems and the environment, personal and cultural adaptation of speed to keep up with the rapid development of science and technology as the inability conflict and confusion should lead to even. This paper the characteristics of the information society, with a look at the evolution of social risk factors as the wavelength of information about this look at the role of private security sought to evaluate. Information Society in time and space by shrinking the area of human life that has brought the convenience and simplicity, whereas the non-performance due to the nature of anonymous raises many social side-effects are. This made the preparation of national regulatory measures, but for the protection of personal protection devices in the private sector has not yet been discussed. Way of life and property of the purchaser to protect an individual's private security will have to charge it.

• Journal of Korean Academy of Nursing
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• v.30 no.5
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• pp.1207-1218
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• 2000

This study examined all the research published in Journal of Korean Academy of Nursing (JKAN) for last 30 years, from its beginning year to year 1999, based on an objective frame of evaluation. The purpose of this study is to reflect the trend of nursing research in Korea to date, and to provide an optimal direction for future research. The total number of 959 studies were analyzed with the following results. 1. Since 1990s, the number of non-degree based research has been larger than that of degree-based research compared to 1970s and 1980s. Both collaborative and funded research has been particularly increased in a gradual rate. 2. Research on nurses or nursing students has decreased while research on more diverse populations such as patients, patient families, or community-dwelling healthy clients has increased. 3. While essential nursing concepts such as human, nursing, and health have been consistently dealt as main research topics, research related to the concept of environ- ment has been insufficiently conducted. 4. It was remarkable that the quality of nursing research has been improved due to the acknowledgement of the importance of the empirical research method within the nursing community. 5. Qualitative research has appeared in the journal since the late 1990s, but it is still regarded to be in its novice stage. 6. Although the utilization of research findings for expanding the nursing body of knowledge has been wide in diverse specialties, most studies are limited to focus on concept development or evolution yet. also, in some of these research finding are utilization already considerably as to develop nursing interventions. Based on these findings, conclusions are extended to the following discussions: For the last 30 years, nursing research in Korea has shown an acute methodological development in both quantity and quality. However, there has been a lack of research on theory development although it is one of the ultimate goals in nursing. Further research should be empirical enough to be utilized in an actual nursing care context, and thus to be basis of developing culturally competent nursing theories in Korea.

• Journal of the Korean earth science society
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• v.21 no.5
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• pp.635-646
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• 2000

Geological achievements of the 20th century revolutionized our views about geological understanding and concept. A good example is the concept of continental drift suggested early in the 20th century and later explained in terms of seafloor spreading and plate tectonics. Our understanding of the compositions of materials forming earth has also improved during the20th century. Radio and stable isotopes together with biostratigraphy and sequence stratigraphy allow us to interpret the evolution of sedimentary basins in terms of plate movement and sedimentation processes. The Deep Sea Drilling Project initiated in 1960s and continued as the Ocean Drilling Project in 1980s is one of the most successful international research observations, and new developments in computational techniques have provided a wholly new view about the interior of the earth. Most of the geological features and phenomena observed in deep sea and around continental margins are now explained in terms of global tectonic processes such as superplumes flowing up from the interior of our planet and interacting with such as Rodinia Pannotia and Nena back in the Precambrian time. The space explorations which began in the late 1950s opened up a new path to astrogeology, astrobiology, and astropaleontology. The impact theory rooted in the discovery of iridium and associated phenomena in 1980s revived Cuvier's catastrophism as a possible explanation for the extinctions of biotas found in the geological record of this planet. Due to the geological achievements made in the 20th century, we now have a better understanding of geologic times and processes that were too long to be grasped by human records.

• Korea and Global Affairs
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• v.1 no.1
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• pp.115-152
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• 2017

This paper is to analyse the changes in the future war patterns and ROK's response. To this end the paper is composed of 5 chapters titled instruction; concept, characteristics, types, and evolution of war; changes in the war patterns of the future; Korea's response strategies for the future war. Truth can be immutable, but everything else changes. War has begun with human history, and today there are still wars in places all over the world. As ages change from agricultural society to industrial society to knowledge and information society, aspects(patterns) of war have also changed. Future warfare includes the 5th dimensional war(in the ground, the sea, the air, the universe, the cyber), the network-centric, the precision strike, the rapid maneuver, the non-gunpowder, the non-lethal, the unmanned robot, the informational & cyber, the asymmetric, the non-linear, and the parallel etc. In response to these changes in the pattern of wars, the ROK military should seek (1)to build a future-oriented military force, (2)to continuously develop military innovation and preparedness, and (3)to develop and establish a paradigm for acquiring the power of technology. A Roman strategist, Vegetius said, "If you wish peace, prepare for war." This is a universally accepted maxim in international society today. We must never forget that peace we desire is given when we have the will and ability to keep.

• The Journal of the Korea Contents Association
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• v.20 no.10
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• pp.738-749
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• 2020

The stamp commemorating the inauguration of a president is the smallest historical symbol that contains a nation's vision and wishes of the times. The stamp itself is just a collection of images but contains the meaning of the highest leader's perceived image at the time through their face and a symbol. This paper regarded presidential inauguration commemorative stamps in the context of advertisement or promotional materials to structurally analyze the images of the political leaders embedded in stamps utilizing 'semiology' theory, which is considered to be a useful method of advertisement. In accordance with social and cultural changes, the 2000s, when the changes in the presidential inauguration stamp was most distinctively noticeable, was set as the time frame. Only the presidential inauguration commemorative stamps of Moo-hyun Roh, Myung-bak Lee, Geun-hye Park, and Jae-in Moon were selected for this study. In order to interpret the image, a semiotic structure was applied to reconstruct the meaning of the image of the political leaders. Since this can lead to subjective judgment in image analysis, it attempted to find the truth through comprehensive interpretation and approach it from the social and cultural contexts, not a static approach. In this paper, the images of the Korean political leaders in the 2000s shown on stamps are no longer influenced by traditional political factors such as political parties, political ideologies, and regional origins due to the evolution of democracy. This study derives the characteristics of the images of independent and characteristic leaders centered on a person according to the situations and social phenomena of the times.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.93-102
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• 2020

The design of large complex mechanical systems, such as automobile, aircraft, and ship, is a kind of Multidisciplinary Design Optimization (MDO) because it requires both experience and expertise in many areas. With the rapid development of technology and the demand to improve human convenience, the complexity of these systems is increasing further. The design of such a complex system requires an integrated system design, i.e., MDO, which can fuse not only domain-specific knowledge but also knowledge, experience, and perspectives in various fields. In the past, the MDO relied heavily on the designer's intuition and experience, making it less efficient in terms of accuracy and time efficiency. Process integration and the design optimization framework mainly support MDO owing to the evolution of IT technology. This paper examined the procedure and methods to implement an efficient MDO with reasonable effort and time using RCE, an open-source PIDO framework. As a benchmarking example, the authors applied the proposed MDO methodology to a bulk carrier's conceptual design synthesis model. The validity of this proposed MDO methodology was determined by visual analysis of the Pareto optimal solutions.

• Microbiology and Biotechnology Letters
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• v.45 no.3
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• pp.226-235
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• 2017

Carotenoids such as phytoene, lycopene, and ${\beta}-carotene$ are used as food colorants, animal feed supplements, and for human nutrition and cosmetic purposes. Previously, we reported the isolation of a novel marine bacterium, Kocuria gwangalliensis, which produces a pink-orange pigment. Phytoene desaturase (CrtI), encoded by the gene crtI, catalyzes lycopene formation from phytoene and is an essential enzyme in the early steps of carotenoid biosynthesis. CrtI is one of the key enzymes regulating carotenoid biosynthesis and has been implicated as a rate-limiting enzyme of the pathway in various carotenoid synthesizing organisms. Here, we report the cloning of the crtI gene responsible for lycopene biosynthesis from K. gwangalliensis. The gene consisted of 1,584 bases encoding 527 amino acid residues. The nucleotide sequence of the crtI gene was compared with that of other species, including Kocuria rhizophila and Myxococcus xanthus, and was found to be well conserved during evolution. An expression plasmid containing the crtI gene was constructed (pCcrt1), and Escherichia coli cells were transformed with this plasmid to produce a recombinant protein of approximately 57 kDa, corresponding to the molecular weight of phytoene desaturase. Lycopene biosynthesis was confirmed when the plasmid pCcrtI was co-transformed into E. coli containing the plasmid pRScrtEB carrying the crtE and crtB genes required for lycopene biosynthesis. The results from this study will provide valuable information on the primary structure of K. gwangalliensis CrtI at the molecular level.