• Title/Summary/Keyword: human cases

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Five human cases of Diphyllobothrium latum infection through eating raw flesh of redlip mullet, Liza haenatocheila (가숭어 (Liza haemotocheila)가 감염원으로 추정되는 광절열두조충 집단감염)

  • 정평림;최운준
    • Parasites, Hosts and Diseases
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    • v.35 no.4
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    • pp.283-290
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    • 1997
  • A total of 32 human diphyllobothriasis cases have been reported so far in Korea, exclud- ing 21 egg-positive cases from stool examinations. Authors experienced five more human cases of DiphHllobothrium latum infection, especially infected due to eating raw flesh of redlip mullet, Lizc hoematocheiln. Five cases were neighbors residing in the Puchon area, Kyonggi-do, who ate raw mullets (L. hQematocheila) in a party in February 1996. The mul- lets were purchased at the Noryangjin fisheries market in Seoul. All of cases (2 males and 3 females) were 35 to 43 years old and healthy with the body weight range of 56-62 kg. They complained about gastrointestinal trouble and abdominal discomfort, but were in normal ranges of their hematology and urinalysis data. None revealed any sign of anemia The patients experienced natural discharge of a chain of segments before, and showed diphyllobothriid eggs in their stool specimens when they visited our laboratory. They were administered with praziquantel (15 mg/kg of body weight) and 30 g of magnesium sulfate as a purgative. Two whole worms with the scolices (310-340 cm in length; 8-13 mm in width) were expelled each from two out of five cases after anthelmintic treatment, and the others expelled the parts of strobilae without scolex. The worms were identified as D. Ictum, based on the following biological characters. external morphologies, coiling of uterus, the number of uterine loops, position of genital opening, morphologies of cirrus, cirrus sac and seminal vesicle on the histological sections, position of vagina and uterine pore , and microscopical and SEM morphologies of the eggs.

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Human Papillomavirus Testing with Hybrid Capture II and DNA Chip

  • Im Jee-Aee;Shim Moon-Jung;Ryang Yong-Suk;Lee Duk-Chul
    • Biomedical Science Letters
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    • v.11 no.1
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    • pp.51-56
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    • 2005
  • The detection of high-risk human papilloma virus (HPV) allows us to predict the presence and future development of cervical intraepitheliallesion. In this study, we compared Hybrid Capture II and DNA chip methods for detection of HPV in cervical swab samples. And we evaluated the clinical efficacy and diagnostic performance of HPV DNA chip and Hybrid Capture II for detecting HPV in cervical neoplastic lesions. Seventy four patients were classified into three groups according to their histologic diagnosis: Group I (nonspecific chronic cervicitis), Group II (low-grade squamous intraepithelial lesion (SIL); koilocytosis, and mild dysplasia), and Group III (high-grade SIL;, moderate, severe dysplasia and in situ carcinoma). Cytologic diagnosis were based on the Bethesda System. Hybrid Capture II and DNA chip methods were performed to detect HPV. In 41 of the 74 cervical samples $(55.4\%)$, HPV DNAs were detected by Hybrid Capture II. In Group III, HPV-positive cases were detected in 15 $(20.3\%)$ of 74 patients by Hybrid Capture II. 25 patients with ASCUS cytology were histopathologically examined: 9 cases $(36\%)$ were Group II. In 18 patients with low-grade SIL cytology, 13 cases $(72.2\%)$ were Group II and 3 cases $(16.7\%)$ were Group III. 12 cases $(92.3\%)$ were Group ill of 13 patients with high-grade SIL cytology. The sensitivity of each test was $82\%$ in Hybrid Capture II and $53.9\%$ in DNA chip test. And the specificity was $74.3\%,\;85.7\%$ in Hybrid Capture II and DNA chip. In conclusion, Hybrid Capture II test is more sensitive than DNA chip in detecting women with cervical neoplastic lesions. Especially, in diagnosing of ASCUS, Hybrid Capture II test is more sensitive. Therefore, Hybrid Capture II test for cancer-associated HPV DNA is a viable option in the management of women with ASCUS.

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Expression of P-glycoprotein is Positively Correlated with p53 in Human Papilloma Virus Induced Squamous Intraepithelial Lesions of Uterine Cervix: Poor Prognosis Association

  • Singh, Madhulika;Singh, Uma;Mathur, Neeraj;Shukla, Yogeshwer
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.12
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    • pp.6039-6045
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    • 2012
  • This study was conducted to assess the predictive value of p-glycoprotein (p-gp) and p53 immunoexpression in human papillomavirus (HPV) infected cases of cervical dysplasia. Expression of both p-gp and p53 proteins was detected in cervical smears from 177 squamous intraepithelial lesions (SIL) cases along with 183 "atypical squamous cells of unknown significance" (ASCUS) and 150 normal cases. HPV 16 and 18 infection was detected by polymerase chain reaction using type-specific primers for HPV sub-types. There were no significant detectable p53 and p-gp expression in the normal cervix smears (p>0.05). In the ASCUS group 10 cases were positive for both p53 and p-gp immunoreactivity. In cervical dysplasia cases, p53 was positive in 86 (48.58%) while p-gp was positive in 93 (52.54%) and the two markers showed a highly significant correlation (r=0.92, p<0.001). Expression of p53 and p-gp was associated with grade of SIL (p<0.001). A positive correlation between the presence of HPV and expression of proteins p53 and p-gp in smears of patients with cervical lesions was also noted (p<0.001). Thus, p53 and p-gp immunostaining in cervical smears may act as an auxiliary biomarker for detection of HPV-associated cervical lesions. Additionally, a significant positive correlation between ascending grades of SIL and labeling indices of markers suggests that p53 and p-gp can be used as an adjunct to cytomorphological interpretation of conventional cervical Pap smears.

Recognizing asymmetric moire patterns for human spinal deformity detection

  • Kim, Hyoung-Seop;Hiroshi UENO;Seiji ISHIKAWA;Yoshinori Otsuka
    • 제어로봇시스템학회:학술대회논문집
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    • 1997.10a
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    • pp.568-571
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    • 1997
  • Recently, the number of techniques for analyzing medical images has been increasing in computer vision, employing X-ray CT images, ultrasound images, MR images, moire topographic images, etc. Spinal deformity is a serious problem especially for teenagers and medical doctors inspect moire topographic images of their backs visually for the primary screening. If a subject is normal, the moire image is almost symmetric with respect to the middle line of the subject's back, otherwise it shows asymmetric shape. In this paper, an image analysis technique is described for discriminating suspicious cases from normal in human spinal deformity by recognizing asymmetric moire images of human backs. The principal axes which are sensitive to asymmetry of the moire image are extracted at two parts on a subject's back and their angles are evaluated with respect to the detected middle line of the back. The two angles compose a 2-D feature space and inspected cases are divided into two clusters in the space by a linear discriminant function based on the Mahalanobis distance. Given 120 cases, 60 normal and 60 abnormal, the leave-out method was applied for the recognition and 75% recognition rate was achieved.

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A Study on the Channel Noise on VDT Workstation (VDT 작업환경에서 경로노이즈에 관한 연구)

  • Kwon, Kyu-Sik;Choi, Chul
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.25 no.1
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    • pp.71-77
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    • 2002
  • This study deals with noise occurring in the process of human information transmission. Human process many kinds of information by receiving them from the outside or using their own thought and express the processed information to the outside by acting. In this process, Channel Noise ($C_N$) is defined as the characteristics of noise generating the incomplete result for the external stimulus. To evaluate $C_N$, keyboard-typing experiment has been performed to the 87 subjects. In this experiment, the subject consists of college students who have abundant experience in computer usage. In the experiment, there were some cases that typing order was unconsciously reversed. In this study, we deal with only these cases since these cases can be used as important data to study humans information transmission system.

Two human cases of tick bite caused by Ixodes nipponensis

  • Ko, Jung-Hun;Cho, Do-Youn;Chung, Byoung-Soo;Kim, Suk-Il
    • Parasites, Hosts and Diseases
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    • v.40 no.4
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    • pp.199-203
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    • 2002
  • We report two human cases of tick bite. A 63-year-old male had a pruritic pea-sized brownish nodule on the left popliteal area. Another 41-year-old male had an asymptomatic bean-sized black nodule in the pubic area. The ticks were identified as Ixodes nipponenis, which are the 18th and the 19th cases in Korea.

Eight cases of canine thelaziosis found in two localities in Korea

  • Seongjun Choe;Sunmin Kim;Tilak Chandra Nath;Jeong-Ho Kim
    • Parasites, Hosts and Diseases
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    • v.61 no.3
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    • pp.325-331
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    • 2023
  • Thelazia callipaeda, a parasitic nematode that causes thelaziosis in various mammals, including humans, is known to be endemic in Korea. However, life cycle-related information on the parasite, primarily from human infection and a few dog cases, is limited. This study reports additional cases of T. callipaeda infections in dogs from both rural and urban areas in Korea, indicating the potential for transmission to humans and other animals. We collected 61 worms from 8 infected dogs from Paju and Cheongju Cities and observed their morphological characteristics under a light microscope. The findings indicate that T. callipaeda infections in animals in Korea may be underestimated and are distributed close to human environments. Our results contribute to the growing knowledge of the reservoir hosts of T. callipaeda in Korea and highlight the importance of continued surveillance and research to prevent and control this emerging zoonotic disease.

Genotypic Characterization of Salmonella enterica Serotype Enteritidis Isolated from Food-Poisoning Cases and Chickens by Pulsed Field Gel Electrophoresis

  • Suh Dong Kyun;Song Jae Chan
    • Biomedical Science Letters
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    • v.11 no.1
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    • pp.9-13
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    • 2005
  • A total of 22 Salmonella enterica serotype Enteritidis (S. Enteritidis) isolates from human and chicken sources were analyzed by pulsed field gel electrophoresis (PFGE) using XbaI restriction enzyme to assess the genetic relationships between strains from different sources. PFGE permitted the resolution of XbaI restriction fragments of the 22 S. Enteritidis into 6 distinct PFGE types (PFT), designated PFT1 to PFT6, and 2 subtypes within PFT2, and allowed to detect between 9 and 10 bands with fragments sizes in the range of $25\~635\;kb$. Four of twelve isolates from human showed an identical PFGE patterns with 2 isolates from chickens. Also, another one isolate from human showed an identical PFGE patterns with other 5 isolates from chickens. Only one isolate from chicken, however, showed a different pattern compared to other PFTs. These results suggested that sporadic human food-poisoning cases infections caused by S. Enteritidis in this study were due to the consumption of contaminated chicken meats and that a clonally highly similar strains exist and spread between human and chicken sources.

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Research on Career Development Program Management for Global Empowerment - Based on Cases of IoE Management - (글로벌 역량강화를 위한 커리어 개발프로그램 운영 연구 - IoE 운영사례를 중심으로 -)

  • Kwon, Jungin;Ryoo, Intae
    • Journal of Engineering Education Research
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    • v.18 no.6
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    • pp.18-23
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    • 2015
  • Nowadays, IT that leads information era is closely connected to our lives. The importance of training human resources for global empowerment on IT is being emphasized all over the world. With the growth of international society, the cultivation of global human resources now includes the cultivation of future human resources and the educations related with the career development program. However, the programs that colleges are operating for the cultivation of global human resources have been limited only to supporting the participation in international training program, operating camp and conferences, etc. On the contrary, to give many learners chances of experiencing courses for global empowerment and employment capability, We are operating the Internet of Everything online education program with Cisco Networking Academy Korea. Based on the management cases of Internet of Everything online education program, this thesis is suggesting a career program on global empowerment that many learners can experience, different from the limitation of the existing program.

Verification of Human Error Factors for Access Control of Bodyguards through Multiple Risk Case Analysis

  • Kim, Jin-Hwan;Kim, Sang-Jin
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.9
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    • pp.143-150
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    • 2020
  • The purpose of this study is to investigate the human error of bodyguards caused in the process of performing access control activities between security missions, focusing on multiple risk cases, and to suggest countermeasures accordingly. To verify this, after arranging the sequence of events in a time series, the VTA technique and Why-Why analysis technique that can easily identify the problem centered on the variable node were used. In addition, environmental factors and personal factors that cause human errors were extracted through M-SHEL Metrix. As a result of analyzing multiple risk cases through such a method, the security environment factors that cause access control accidents include lack of time (impatience), prejudice against visitors, intensive work methods, lack of security management, unattended travel, and familiar atmosphere. (Relaxation), formal work activities, convenience provision, and underestimation were surveyed. In addition, human errors caused by personal security guards were investigated as low alertness, formal work, negligence of inspection, and comfortable coping.