• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2010년도 춘계 학술발표회
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• pp.740-746
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• 2010

Most important characteristics of calcareous sand are the particle angularity and hollow structure. These characteristics lead to the different behavior of calcareous sand compared to siliceous sand. This study performs a series of dilatometer test using calibration chamber, in order to analyze the effect of particle characteristic of calcareous sand on DMT indices. From experimental test, it is observed that the horizontal stress index($K_D$) and dilatometer modulus($E_D$) of calcareous Jeju sand is underestimated compared to siliceous sand. This is because the particle crushing during penetration induces the less contraction of the dilatometer membrane. A slightly smaller influence of particle crushing is reflected in $E_D$ rather than $K_D$, because $P_1$ pressure reflects the deformation characteristics of un-crushed particle relatively well. It is also observed that $K_D$ of Jeju sand is differently influenced by the vertical effective stress compared with that of siliceous sand.

• Structural Engineering and Mechanics
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• 제53권1호
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• pp.173-188
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• 2015

Several structural calamities in the second half of the 20th century have shown that adequate collapse-resistance cannot be achieved by designing the individual elements of a structure without taking their interconnectivity into consideration. It has long been acknowledged that membrane behaviour of reinforced concrete structures can significantly increase the robustness of a structure and delay a complete collapse. An experimental large-scale test was conducted on a horizontally restrained, continuous reinforced concrete slab exposed to an artificial failure of the central support and subsequent loading until collapse of the specimen. Within this investigation the development of catenary action associated with the formation of large displacements was observed to increase the ultimate load capacity of the specimen significantly. The development of displacements, strains and horizontal forces within this investigation confirmed a load transfer process from an elastic bending mechanism to a tension controlled catenary mechanism. In this contribution a special focus is directed towards strain and crack development at critical sections. The results of this contribution are of particular importance when validating numerical models related to the development of catenary action in concrete slabs.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2003년도 봄 학술발표회 논문집
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• pp.111-116
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• 2003

Instrumentation system in Concrete Face Rockfill Dam(CFRD) can give special attention to the deformation characteristics of the rockfill and behavior of the concrete membrane during construction, reservoir filling and subsequent phase of operation. It also contains data about vertical and transversal compressibility moduli of the rockfill, deflections in the concrete slab, and draws comparisons with other concrete face rockfill dams of recent construction. In this paper, the internal deformation data from D dam monitored by means of hydrostatic settlements cells are analyzed. Observations cover the construction stage, reservoir filling and up to March 1991. The above method can be concluded D dam was well constructed and maintained.

• 대한후두음성언어의학회지
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• 제12권2호
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• pp.158-160
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• 2001

Ankyloglossia is the presence of a lingual frenulum, which can range from a mucous membrane band to a short and thick band and, in extreme cases, to fusion of the tongue to the floor of the mouth. The effects of such a condition, in addition to speech defects and occasionally restriction of sucking, including dental deformities, such as open bite, or even prognathism. Treatment is surgical. The preferred treatment is horizontal sectioning of the frenulum down to the lingual septum and then suturing of the mucosa. The main problem after the healing of surgical wound is adhesion and contracture. Adhesion restrict the movement of tongue like tongue-tie. Z-plasty at the site of incision can solve this problem by changing the direction of scar. We have experienced a patient with ankyloglossia with speech defect, who underwent frenuloomy by Z-plasty. So we present a surgical treatment of Ankyloglossia using Z-plasty and discuss the treatment with a review of literature.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2008년도 춘계학술대회 논문집
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• pp.550-553
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• 2008

In this paper, experiments of air-breathing proton exchange membrane fuel cell (PEMFC) for mobile devices were carried out according to the cathode conditions. These conditions are defined by the cathode flow field plate type (the channel type, the open type) and the cathode surface direction. Single cell and 6-cell stack were used in this experiments. The experimental results showed that the open type cathode flow field plate gave better performance for small size PEMFCs because the open type cathode plate allowed better air convection than the channel type cathode plate. In the experiments related to the direction of the slits on the cathode flow field plate, the horizontal slit cell was better than the vertical slit cell. With respect to the cathode surface direction, when the cathode surface is placed in the direction normal to the ground, PEMFC generated more stable power in the mass transport loss region.

• 한국정밀공학회지
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• 제16권7호
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• pp.24-31
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• 1999

Bulging is a forming method to shape of die cavity by using hydraulic pressure in tube or vessel. Bulging machine and die were developed in order to produce vessel for keeping warm. Bulging machine is a double type with two horizontal cylinders for bulging of two pieces at the same time. The developed die system has one bulging die and two drawing dies for necking at the both ends of tube. The diameter of tube expands by hydraulic pressure in tube. at the same time, thrust at the both ends of tube. pushes tube in the direction of expansion to obtain high expanding rate with no crack. In this study, the bulging properties were investigated to solve tube crack and necking in manufacturing vessel by the combination method of bulging and drawing. As a result, high expanding rate of tube radius without crack, precision necking and high productivity were obtained.

• 한국응용과학기술학회지
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• 제17권2호
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• pp.126-131
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• 2000

Transdermal therapeutic system(TTS) is often used as the method of drug dosage into the epidermic skin. Natural polymer were selected as ointment material of TTS. We investigated the permeation of natural polymer ointment containing drug in rat skin using horizontal membrane cell model. Permeation properties of materials were investigated for water-soluble drug such as oxiniacic acid in vitro. These results showed that skin permeation rate of drug across the composite was mainly dependent on the property of ointment base and drug. Proper selection of the polymeric materials which resemble and enhance properties of the delivering drug was found to be important in controlling the skin permeation rate. This result suggests a possible use of natural polymer ointment base as TTS of antihyperlipoproteinemic agent.

• International Journal of Precision Engineering and Manufacturing
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• 제2권4호
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• pp.40-46
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• 2001

Bulging is a forming method to shape die cavity by using hydraulic pressure in tube or vessel. Bulging machine and die were developed in order to produce vessel for keeping warm. Bulging machine is a double type with two horizontal cylinders for bulging of two pieces at the same time. The developed die system has one bulging die and two drawing dies for necking at both ends of the tube. The diameter of tube expands by hydraulic pressure in tube. At the same time, thrust at both ends of the tube pushes tube in the direction of expansion to obtain high expansion rate with no crack. In this study, the bulging properties were investigated to solve tube crack and necking in manufacturing vessel by combining bulging and drawing. As a result, high expanding rate of tube radius without crack, precision necking and high productivity were obtained.

• 한국응용과학기술학회지
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• 제25권2호
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• pp.123-129
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• 2008

Transdermal therapeutic system(TTS) is often used as the method of drug dosage into the epidermic skin. Natural polymer were selected as ointment material of TTS. We investigated the permeation of natural polymer ointment containing drug in rat skin using horizontal membrane cell model. Permeation properties of materials were investigated for water-soluble drug such as Nicotinic acid N-oxide in vitro. These results showed that skin permeation rate of drug across the composite was mainly dependent on the property of ointment base and drug. Proper selection of the polymeric materials which resemble and enhance properties of the delivering drug was found to be important in controlling the skin permeation rate. This result suggests a possible use of natural polymer ointment base as TTS of antihyperlipoproteinemic agent.

• BMB Reports
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• 제56권6호
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• pp.335-340
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• 2023

During normal physiological and abnormal pathophysiological conditions, all cells release membrane vesicles, termed extracellular vesicles (EVs). Growing evidence has revealed that EVs act as important messengers in intercellular communication. EVs play emerging roles in cellular responses and the modulation of immune responses during virus infection. EVs contribute to triggering antiviral responses to restrict virus infection and replication. Conversely, the role of EVs in the facilitation of virus spread and pathogenesis has been widely documented. Depending on the cell of origin, EVs carry effector functions from one cell to the other by horizontal transfer of their bioactive cargoes, including DNA, RNA, proteins, lipids, and metabolites. The diverse constituents of EVs can reflect the altered states of cells or tissues during virus infection, thereby offering a diagnostic readout. The exchanges of cellular and/or viral components by EVs can inform the therapeutic potential of EVs for infectious diseases. This review discusses recent advances of EVs to explore the complex roles of EVs during virus infection and their therapeutic potential, focusing on HIV-1.