• Title/Summary/Keyword: homogenization

Search Result 645, Processing Time 0.032 seconds

Development of Chitosan Coated Solid Lipid Nano-particles Containing 7-Dehydrocholesterol (7-디하이드로콜레스테롤을 함유한 키토산 코팅 처리 Solid Lipid Nano-particle의 개발에 관한 연구)

  • Lee Geun-Soo;Kim Tae-Hoon;Lee Chun-Il;Pyo Hyeong-Bae;Choe Tae-Boo
    • Journal of the Society of Cosmetic Scientists of Korea
    • /
    • v.31 no.2 s.51
    • /
    • pp.141-146
    • /
    • 2005
  • Unstable cosmetic active ingredients could rapidly break down in chemical and photochemical process. Therefore, it has become a very important issue to encapsulate active ingredient for the stabilization. 7-Dehydrocholesterol (7-DHC), a precursor of vitamin $D_3$, has been shown to increase levels of protein and mRNA for heat shock protein in normal human epidermal keratinocytes. However, topical dermal application of 7-DHC is restricted due to its poor solubility and chemical unstability. In this study, 7-DHC was incorporated into nano-emulsion (NE), solid lipid nano-particle (SLN), and chitosan coated solid lipid nano-particle (CASLN), respectively. In order to prepare NE and SLN dispersion, high-pressure homogenization at temperature above the melting point of lipid was used Hydrogenated lecithin and polysorbate 60 were used as stabilizer for NE and SLN. CASLN was prepared by high speed homogenizing after adding chitosan solution to the SLN dispersion and showed positively charged particle properties. Decomposition rate of 7-DHC in NE, SLN and CASLN was studied as a function of time at different temperature. Differential scanning calorimetry (DSC) and X-ray diffraction (XRD) studies were performed to characterize state of lipid modification. It appeared that CASLN is the most effective to stabilize 7-DHC and may be used for a useful topical dermal delivery system.

Survey of radioactive contamination in imported foodstuffs (수입 식품중의 방사능 오염실태 조사)

  • Lee, Wan-No;Lee, Haeng-Pil;Chung, Kun-Ho;Kim, Hee-Reyoung;Cho, Young-Hyun;Choi, Geun-Sik;Lee, Chang-Woo;Chung, Hyung-Wook;Lee, Eun-Ju;Sho, You-Sup;Lee, Jong-Ok
    • Journal of Radiation Protection and Research
    • /
    • v.31 no.3
    • /
    • pp.141-148
    • /
    • 2006
  • Surveys of radioactive contamination were performed for imported foodstuffs in 2003. The following samples among imported foodstuffs were selected from markets and Korea Food and Drug Administration(KFDA); the imported samples from country associated with the Chernobyl nuclear accident, the samples produced around the nuclear power plants or nuclear tests, the foodstuffs reported as radioacitive contamination materials in foreign country. After pretreatments such as drying and homogenization, samples were analyzed. The $^{137}Cs$ radionuclide was only measured among the regulation radionuclides($^{137}Cs,\;^{134}Cs,\;^{131}I$) of food code. All foodstuffs except Inonotus Obliquus(Chaga mushooms) are less than 17.0 Bq/kg or below the minimum detectable activity(MDA). The activity concentrations of Chaga mushrooms from Russia ranged up to 131.25 Bq/ltg which is almost 35 % of the maximum permitted level of food code. The fraction of imported foodstuffs having meaningful radioactivity is small, however, the radioactive contamination survey of imported foodstuffs is still needed.

A Basic Study on the Production of $Sm_{2}Fe_{17}N_{x}$ System Rare Earth Permanent Magnet by the Reduction and Diffusion(I) - Production of Alloy Powder of $Sm_{2}Fe_{17}$ Intermetallic Compound - (환원.확산법에 의한 $Sm_{2}Fe_{17}N_{x}$ 계 희토류 영구자석의 제조에 관한 기초연구(제 1보) -$Sm_{2}Fe_{17}$금속간화합물 합금분말의 제조-)

  • Song, Chang-Bin;Choo, Tong-Rae
    • Korean Journal of Materials Research
    • /
    • v.8 no.8
    • /
    • pp.720-725
    • /
    • 1998
  • As a basic study on the production of $Sm_{2}Fe_{17}N_{x}$ system rare earth permanent magnet by the reduction and diffusion(R- D) process, firstly the reduction reaction of $Sm_2O_3$ by metallic Ca and diffusion of Sm into Fe powder was investigated for the production the $Sm_{2}Fe_{17}$intermetallic compound. We concluded that the former case was very rapidly completed under the high temperature greater than 100$0^{\circ}C$ and the latter case of completion of diffusion reaction of Sm into the center of Fe powder(perfect homogenization condition) was required through 3h R- D reaction at 110$0^{\circ}C$ and identified as a rate determining step(RDS) on the whole reaction. Though $SmFe_2,SmFe_3$, and $Sm_{2}Fe_{17}$phases in the growth of phases of intermetallic compound in the Sm - Fe binary system were obseved below 100$0^{\circ}C$, but only $Sm_{2}Fe_{17}$phase was observed at lIOO$^{\circ}C$. Oxygen and Ca contents of the final sample in this work were 0.72wt% and O. 11 wt% respectively.

  • PDF

Geopung Copper Deposit in Ogcheon, Chungcheongbuk-do: Mineralogy, Fluid Inclusion and Stable Isotope Studies (거풍구리광상: 산출공물, 유체포유물 및 안정동위원소 연구)

  • Yoo, Bong-Chul;You, Byoung-Woon
    • Economic and Environmental Geology
    • /
    • v.44 no.3
    • /
    • pp.193-201
    • /
    • 2011
  • The Geopung Cu deposit consists of two subparallel quartz veins that till the NE-trending fissures in Triassic Cheongsan granite. The quartz veins occur mainly massive with partially cavity and breccia. They can be followed along strike for about 500 m and varies in thickness from 0.2 to 2.2 m. Based on the mineralogy and paragenesis of veins, mineralization of quartz veins can be divided into hypogene and supergene stages. Hypogene stage is associated with hydrothermal alteration minerals such as sericite, pyrite, quartz, chlorite, clay minerals and sulfides such as pyrite, arsenopyrite, pyrrhotite, marcasite, sphalerite, stannite, chalcopyrite and galena. Supergene stage is composed of geothite. Fluid inclusion data from quartz indicate that homogenization temperatures and salinity of hypogene stage range from 163 to $356^{\circ}C$ and from 0.2 to 7.2 wt.% eq. NaCl, respectively. They suggest that ore forming fluids were progressively cooled and diluted from mixing with meteoric water. Sulfur (${\delta}^{34}S$: 4.3~9.2‰) isotope composition indicates that ore sulfur was derived from mainly magmatic source although there is a partial derivation from the host rocks. The calculated oxygen (${\delta}^{18}O$: 0.9~4.0‰) and hydrogen (${\delta}D$: -86~-69‰) isotope compositions suggest that magmatic and meteoric ore fluids were equally important for the formation of the Geopung Cu deposit and then overlapped to some degree with another type of meteoric water during mineralization.

Effects of Egg White and Ion Exchange Resin Pretreatment on Separation of Egg White Lysozyme (난백 및 이온교환수지의 전처리 조건이 난백 Lysozyme의 추출에 미치는 영향)

  • 유익종;이성기;김경환;민병용
    • Korean Journal of Poultry Science
    • /
    • v.16 no.3
    • /
    • pp.157-167
    • /
    • 1989
  • Pretreatment of egg white and ion exchange resins was attempted to separate lysozyme from egg white efficiently. Apparent viscosity of egg white could be decreased to 3cp by homogenization for 30 minutes at 2, 000rpm and ultrasonication for 45 minutes. The result of testing adsorption capacity of lysozyme was as follows; CM-Sephadex C-25 >Duolite C464>Amberlite C-50>Dowex MSC-1>Amberlite IRC-50>Amberlite IRC-84. Although CM-Sephadex C-25 showed highest adsorption capacity of lysozyme, egg white could not eluted easily. Duolite Cf64 was selected based on relatively high lysozyme adsorption and good egg white eluting property for separation of egg white lysozyme. Na$^{+}$ form of Duolite C-464 was most effective on adsorption of Iysozyme. To separate lysozyme from egg white efficiently rinse buffer and eluting solution were selected 0.1M sodium phosphate buffer at pH 6.5 and 10% ammonium sulfate respectively. After separating lysozyme from egg white, foaming power of egg white was decreased to 85.3%. Color of egg white gel was not changed while hardness of egg white gel was decreased by 30% after separating lysozyme. However, elasticity of egg white gel was increased by 13% in lysozyme-separated egg white.

  • PDF

Fluid Inclusion and Stable Isotope Studies of Mesothermal Gold Vein Deposits in Metamorphic Rocks of Central Sobaegsan Massif, Korea: Youngdong Area (소백산 육괴 중부 지역의 변성암에서 산출되는 중온형 금광상에 대한 유체 포유물 및 안정동위원소 연구. 영동지역)

  • Chip-Sup So
    • Economic and Environmental Geology
    • /
    • v.32 no.6
    • /
    • pp.561-573
    • /
    • 1999
  • Mesothermal gold deposits of the Heungdeok, Daewon and Ilsaeng mines in the Youngdong area occur in fault shear zones in Precambrian metamorphic rocks of central Sobaegsan Massif, Korea, and formed in single stage of massive quartz veins (0.3 to 3 m thick). Ore mineralogy is simple, consisting dominantly of pyrrhotite, sphalerite and galena with subordinate pyrite, chalcopyrite, electrum, tetrahedrite and native bismuth. Fluid inclusion data indicate that hydrothermal mineralization occurred at high temperatures (>240$^{\circ}$ to 400$^{\circ}$C) from $H_{2}O-CO_{2}(-CH_{4})$-NaCI fluids with salinities less than 12 wt. % equiv. NaC!. Fluid inclusions in vein quartz comprise two main types. These are, in decreasing order of abundance, type I (aqueous liquid-rich) and type II (carbonic). Volumetric proportion of the carbonic phase in type II inclusions varies widely in a single quartz grain. Estimated $CH_4$ contents in the carbonic phase of type II inclusions are 2 to 20 mole %. Relationship between homogenization temperature and salinity of fluid inclusions suggests a complex history of fluid evolution, comprising the early fluid's unmixing accompanying $CO_2$ effervescence and later cooling. Estimated pressures of vein filling are at least 2 kbars. The ore mineralization formed from a magmatic fluid with the ${\delta}^{34}S_{{\Sigma}S}$, ${\delta}^{18}O_{water}$ and ${\delta}D_{water}$ values of -2.1 to 2.2$\textperthousand$, 4.7 to 9.3$\textperthousand$ and -63 to -79$\textperthousand$, respectively. This study validates the application of a magmatic model for the genesis of mesothermal gold deposits in Youngdong area.

  • PDF

The hardening effect by ice-quenching after oxidation of a Pd-Ag-Sn-Au metal-ceramic alloy during porcelain firing simulation (금속-세라믹용 Pd-Ag-Sn-Au계 합금의 모의소성 시 산화처리 후 급랭에 의한 경화 효과)

  • Shin, Hye-Jeong;Kim, Min-Jung;Kwon, Yong-Hoon;Kim, Hyung-Il;Seol, Hyo-Joung
    • Korean Journal of Dental Materials
    • /
    • v.44 no.3
    • /
    • pp.197-206
    • /
    • 2017
  • The hardening effect by ice-quenching after oxidation of a Pd-Ag-Sn-Au metal-ceramic alloy during porcelain firing simulation was investigated by means of hardness test, field emission scanning electron microscopic observations, and X-ray diffraction analysis. The hardness decreased by ice-quenching after oxidation, which was induced by the homogenization of the ice-quenched specimen. The decreased hardness by ice-quenching after oxidation was recovered from the wash stage which was the first stage of the remaining firing process for bonding porcelain. After wash stage, the hardness of the ice-quenched specimens decreased during the subsequent porcelain firing process. But the final hardness of the ice-quenched specimens after oxidation was higher than that of the specimens cooled at stage 0 after oxidation. The increase in hardness of the specimens during the first firing process was caused by the lattice strains generated at the interface between the face-centered cubic Pd-Ag-rich matrix and the face-centered tetragonal Pd3(Sn, Ga, In) precipitate. The decrease in hardness of the specimens during the remaining firing process was caused by the microstructural coarsening.

Diaspora and National policy - Focusing on Russian Diaspora and chinese Diaspora (디아스포라와 국가정책 - 러시안 디아스포라와 차이니즈 디아스포라를 중심으로)

  • Chun, Byung Kuk
    • Cross-Cultural Studies
    • /
    • v.26
    • /
    • pp.123-144
    • /
    • 2012
  • In the modern society in which globalization and localization proceed simultaneously, diversified and rapid migration of diaspora makes a new from of boundary off the frame of the state and the nation. This new border accompanies cultural change and racial mixture; retains ethnic conflict, the gap between rich and poor, alienation and discrimination, as well as power conflict; and extends its influence. Nowadays, the countries all over the world including Korea face problem of Diaspora in numerous forms. And each country takes an approach to the problem of the diaspora in the aspects of their society, culture and political technology. This implies that most countries, without understanding the new form of border which is alive and dynamic, define and conceptualize the diaspora in the frame of one state and one nation to carry forward the policies accordingly, resulting in inequal, incomplete and awkward homogenization. This study aimed to explore the identity of the diaspora, the core for the problem solving. Of course, studies about the identity of the diaspora have been continued until today and many great outcomes have been achieved. Nevertheless, this study aimed to explore the identity of the diaspora and the national policies which have a close interrelationship with it. It is because the study ultimately aimed to highlight the interrelationship between the destination countries, Russia and China, and the diaspora, through the definition and the classification of Russian diaspora and Chinese diaspora and the analysis of the national policies about that. However, the intention was not to distinguish superiority through the comparison of the polices about the diaspora between two countries, but to focus on the diversity of the identity of the diaspora through defining each different diaspora and paralleling the policies. Second, the reason for looking into the diaspora policies of these two countries is because it is judged the changes in the diaspora policies of each country is one of the active factors for the changes in the identify of the diaspora of each country and it is the basic research for the study on the identity of the diaspora. New migration of diaspora changes the identity of the state, and the state makes the policies and enforce the policies, resulting in the influence on the diaspora. This interaction acts as the growth factor for the new boundary. The causes of Russian diaspora and Chinese diaspora show apparent 'differences'. In parallel with this, the policies about the diaspora in Russia and China arouse 'differences' to the diaspora. The variation of the identity of the diaspora made by these differences will suggest other viewpoints on the diaspora, and these viewpoints will become the foundation for solving the problem of the diaspora in the present times.

Comparison of the stability between branched-chain amino acid (BCAA)-coated liposome and double emulsion (분지쇄아미노산(BCAA)이 포집된 더블에멀션과 리포좀의 안정성 비교)

  • Lee, YunJung;Lee, SangYoon;Shin, Hyerin;Kang, Guhyun;Wi, Gihyun;Ko, Eun Young;Cho, Youngjae;Choi, Mi-Jung
    • Korean Journal of Food Science and Technology
    • /
    • v.50 no.6
    • /
    • pp.636-641
    • /
    • 2018
  • This study was conducted to compare the stability between branched-chain amino acid (BCAA)-encapsulated liposome and double emulsion (DE). Liposome was produced by high-speed homogenization and ultrasonication whereas DE was prepared by homogenizing with surfactants. All samples were fixed at pH 4 and 7 and stored at 4, 25, and $40^{\circ}C$ for 5 days. Encapsulation efficiency and cumulative release rate were measured under $4^{\circ}C$ and at $25^{\circ}C$. The results showed that the size of BCAA-coated liposome was greater at pH 7 than at pH 4. The zeta-potential value of BCAA-coated liposome was greater at pH 4 than at pH 7. It was supposed that the negatively charged liposomes attracted the positively charged BCAAs at pH 4 resulting in the formation of the vesicle with smaller size. Particle size of DE was smaller than $100{\mu}m$. Encapsulation efficiencies of BCAA in DE or liposome were over 97%, approximately, and the cumulative release rates of them were below 30% for 5 days.

Evaluation of Coconut Oil-based Emulsion Stability Using Tween-Span Type Nonionic Mixed Surfactant (Tween-Span계 비이온성 혼합계면활성제를 이용한 Coconut Oil 원료 유화액의 유화안정성 평가)

  • Hong, Seheum;Zhu, Kaiyang;Zuo, Chengliang;Lee, Seung Bum
    • Applied Chemistry for Engineering
    • /
    • v.30 no.4
    • /
    • pp.453-459
    • /
    • 2019
  • In this study, the influence factors on the stability of the O/W (oil in water) emulsions prepared with coconut oil and the nonionic mixed surfactant (Tween 80-Span 80) were evaluated. The concentration and HLB value of the nonionic mixed surfactant, and the degree of agitation were used as manufacture factors. The stability of prepared O/W emulsions were measured with the mean droplet size, zeta-potential, emulsion stability index (ESI), and thermal instability index (TII). The mean droplet size of the prepared O/W emulsions was from 100 to 200 nm. As the concentration of mixed surfactant and the homogenization speed increased, the droplet sizes decreased, while the zeta-potential values increased. The effect of HLB values increased in the order of 6.0, 10.0 and 8.0, and at the HLB value of 8 the smallest mean droplet size as 120 nm was obtained whereas the largest value of the zeta-potential between 10 and 60 mV. From the results of ESI and TII, the stability of prepared O/W emulsions increased in order of 6.0, 10.0 and 8.0 of HLB values, and ESI and TII values were above 80% and below 20% respectively at HLB value of 8.0.