• Title/Summary/Keyword: homogeneity

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Design of Crisscrossed Double-Layer Birdcage Coil for Improving B1+ Field Homogeneity for Small-Animal Magnetic Resonance Imaging at 300 MHz

  • Seo, Jeung-Hoon;Han, Sang-Doc;Kim, Kyoung-Nam
    • Journal of Magnetics
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    • v.20 no.3
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    • pp.308-311
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    • 2015
  • We design a crisscrossed double-layer birdcage (DLBC) coil by modifying the coil geometry of a standard single-layer BC (SLBC) coil to enhance the homogeneity of transmitting magnetic flux density ($B_1{^+}$) along the main magnetic field ($B_0$)-direction for small-animal magnetic resonance imaging (MRI) at 300 MHz. The performance assessment of the crisscrossed DLBC coil is conducted by computational analysis with the finite-difference time domain method (FDTD) and compared with SLBC coil in terms of the $B_1$ and the $B_1{^+}$ distribution. As per the computational calculation studies, the mean value in the two-dimensional $B_1{^+}$ map obtained at the mid-axial slice with the proposed DLBC coil is slightly lower than that obtained with the SLBC coil, but the $B_1{^+}$ value of the DLBC coil in the outermost plane (40 mm away from the central plane) shows improvements of 19.3% and 24.8% over the SLBC coil $B_1{^+}$ value when simulating a spherical phantom and realistic mouse body modeling. These simulation results indicate that, the $B_1{^+}$ homogeneity along the z-direction was improved by using DLBC configuration. Our approach enables $B_1{^+}$ homogeneity improvement along the zdirection, and it can also be applied to ultra-high field (UHF) MRI systems.

Experimental studies of homogeneity and stability honeybee venom using ultra-high performance liquid chromatography (주사제 사용을 위한 봉독의 균질성 및 안정성 평가)

  • Han, Sang Mi;Kim, Se Gun;Hong, In Phyo;Woo, Soon Ok;Jang, Hye Ri;Lee, Kyung Woo
    • Korean Journal of Veterinary Service
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    • v.39 no.2
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    • pp.81-86
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    • 2016
  • Honeybee venom (BV) from Apis mellifera L. has been used as natural antimicrobial compounds in pigs, cows, dairy cattle and chicken farms in Korea. The purpose of this study was conducted to confirm homogeneity and stability of BV dissolved with distilled water or saline solution. Melittin was analyzed with ultra-high performance liquid chromatography (UPLC) for BV to secure the validation of analysis. BV at concentration of 1 mg/mL was dissolved with distilled water or saline solution at room temperature. Homogeneity of BV dissolved with distilled water or saline solution at upper, milddle, and lower layers all satisfied the accuracy and precision criteria. Stability of BV dissolved with distilled water or saline solution for 7 days all satisfied the criterion both light and dark storage condition. BV has satisfied with homogeneity and stability in distilled water or saline solution at room temperature under light or dark condition. The results of this study suggest that BV has a possibility as the substitute of natural antimicrobial agents for the animal drugs and feed additives.

Statistical Homogeneity Tests and Multiple Comparison Analysis for Response Characteristics between Treatments of Bridge Groups (교량 집단의 특성 수준간 통계적 응답 동질성 검정 및 다중 비교 분석)

  • Hwang, Jin-Ha;Kim, Ju-Han;An, Seoung-Su
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.18 no.4
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    • pp.107-117
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    • 2014
  • This study tests homogeneity and performs multiple comparison analysis among treatment levels of each factor group through t-test by materials and analysis of variance by structural type and service period. For that descriptive statistical analysis is performed for static and dynamic response characteristics and their ratios of calculated versus measured values based on a good many safety assessment reports for bridges. Homogeneity and post hoc test based on descriptive statistical analysis provide the measures for homogeneity identification among comparison groups in addition to the statistical reference values such as central tendency, variation and shape. This study is expected to be valuable for structural integrity assessment and design by comparing the measured and calculated values with the reference values for the homogeneous group identified, which can help the engineers review the adequacy of the values and put the group database to practical use.

Evaluation of Homogeneity and Stability of Korean Mussel (Mytilus coruscus) Standards for Cadmium Analysis (카드뮴 분석용 홍합(Mytilus coruscus) 표준물질의 균질성 및 안정성 시험평가)

  • Lee, Ha-Eun;Lee, Jangho;Chung, David;Lee, Soo Yong;Park, Ki-Wan;Shim, Kyu-Young
    • Journal of Environmental Science International
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    • v.28 no.11
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    • pp.1041-1045
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    • 2019
  • In this study, the KS A ISO Guide 35 was applied to develop analytical standards for heavy metal cadmium using the Korean mussel (Mytilus coruscus) and to evaluate the homogeneity and stability of the sample. Some of the crucial characteristics that reference materials must consist include homogeneity and stability of both intra- and inter-bottles. We tested homogeneity using ANOVA analysis and short-term stability using regression analysis. The variations of cadmium concentrations did not significantly differ between intra- and inter-bottles (F=0.41, p=0.90). For short-term stability verification, cadmium analysis results were not statistically significant as a result of the regression analysis (significance F=0.51, p=0.53). This suggests that we can not dismiss the null hypothesis that there is no significant variation in concentrations of cadmium over time. These results indicated that the cryogenic-milling process has statistically proven the short-term stability for materials from mussels in the chemical analysis of cadmium. Therefore, we propose that the Korean mussel's reference material developed for the proficiency test could be used as a tool to evaluate reliability and consistency in laboratories.

A Study on the Development of Soil-based PTMs for Analysis of BTEX (BTEX 분석용 토양 숙련도 표준시료(PTMs) 개발에 관한 연구)

  • Lee, Minhyo;Lee, Guntaek;Lee, Bupyoel;Lee, Wonseok;Kim, Gumhee;Hong, Sukyoung
    • Journal of Soil and Groundwater Environment
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    • v.18 no.5
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    • pp.15-25
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    • 2013
  • In this study, two kinds of soil-based proficiency testing materials (PTMs), NICE-012L and NICE-012R were prepared and certified for Benzen, Toluene, Etylbenzene and Xylene with evaluation of uncertainties. In order to analyse BTEX (Benzen Toluene Etylbenzene Xylene) for the candidate materials, GC/MS was used after pretreatment according to methods of soil analysis by Ministry of Environment. For the homogeneity test among bottles in terms of candidate materials, ISO 13528 and IUPAC Protocol were used and according to the result, both candidate materials showed sufficient homogeneity. Also, the stability test over the candidate materials was accessed according to the ISO Guide 35 by classifying short-term and long-term stability and the result showed that both candidate materials showed decent stability. The reference values of the two candidate materials depending on BTEX components were derived from the average of the 11 samples that were used for verification of the samples' homogeneity. Uncertainty of measurement was combined by uchar that was caused by a characteristic value, $u_{bb}$ that was caused by between-bottle homogeneity, and $u_{stab}$ that was caused by stability, and then combined uncertainty ($u_{PTM}$) was multiplied to the coverage factor (k) derived from the effective degree of freedom from each factor that leads to expanded uncertainty (U) in about 95% of confidence level. The proficiency testing materials developed through this study were supplied to National Institute of Environmental Research (NIER) and utilized as an external proficiency testing materials for evaluating analysis capacity of soil agencies with specialty in terms of soil analysis approved by Minister of Environment.

Research for Lateral Penumbra and Dose Distribution When Air Gap Changing in Proton Therapy Case (양성자치료시 Air Gap 변화에 따른 Lateral Penumbra와 선량분포 변화에 대한 비교 및 연구)

  • Kim, Jae-Won;Sim, Jin-Seob;Jang, Yo-Jong;Kang, Dong-Yun;Choi, Gye-Suk
    • The Journal of Korean Society for Radiation Therapy
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    • v.22 no.1
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    • pp.47-51
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    • 2010
  • Purpose: In the treatment of high-energy protons Air gap (the distance between the patient and the exit Beam) Lateral Penumbra of the changes to the increase in the radiation fields can form unnecessary and Increase the maximum dose at the site of treatment and reduced the minimum dose homogeneity of dose distributions can decline. Air gap due to this change in dose distribution compared to investigate studied. Materials and Methods: Received proton therapy at our institution Lung, Liver patients were selected and the size of six other Air gap in Field A and Field B 2, 4, 6, 8, 10 cm Proton external beam planning system by setting up a treatment plan established. Air gap according to the Lateral Penumbra area and DVH (Dose Volume Histogram) to compare the maximum dose and minimum dose of PCTV areas were compared. In addition, the dose homogeneity within PCTV Homogeneity index to know the value and compared. Results: Air gap (2, 4, 6, 8, 10 cm) at each change in field size were analyzed according to the Lateral Penumbra region Field A Change in the Air gap 2~10 cm by 1.36~1.75 cm, the average continuously increased about 28.7% and Field B Change in the Air gap 2~10 cm by 1.36~1.75 cm, the average continuously increased about 31.6%. The result of DVH analysis for relative dose of the maximum dose According to Air gap 2~10 cm is the mean average of 110.3% from 108.1% to a sustained increased by approximately 2.03% and The average relative dose of minimum dose is the mean average of 93.9% percent to 90.8 percent from the continuous decrease of about 3.31 percent. The result of Homogeneity index value to the according to Air gap 2~10 cm is the 2-fold increase from 1.09 to 2.6. Conclusion: In proton therapy case, we can see the increasing of lateral penumbra area when airgap getting increase. And increasing of Dmax and decreasing Dmin in the field are making increase homogeneity index, So we can realize there are not so good homogeneity in the PCTV. Therefore we should try to minimize air gap in proton therapy case.

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A Design Approach for High Homogeneity Superconducting Magnet with Superconducting Active Shield (고균일 자계발생용 초전도 능동차폐 마그네트의 설계에 관한 연구)

  • Lee, K.H.;Kim, S.D.;Cho, Y.H.;Lee, J.B.
    • Proceedings of the KIEE Conference
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    • 1996.07a
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    • pp.151-153
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    • 1996
  • An optimal design approach is presented for high homogeneity superconducting magnet with superconducting active shield especially for use in magnetic resonance imaging system. This paper is investigated phenomena for the stray magnetic field to get a basic reduction techniques of the unwanted stray magnetic field from the magnet. The present method obtains optimal coil configuration considering constraints for magnetic field homogeneity and leakage field.

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Behavior of Mn Ions in Spinel-type Mn-Zn-Fe Oxide System (스피넬계 Mn-Zn 페라이트의 망간이온이 미치는 영향)

  • 권오흥
    • Resources Recycling
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    • v.9 no.5
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    • pp.11-15
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    • 2000
  • The sample made of $Mn_3O_4$ indicated an excellent frequency dependency for intial permeability and core loss. Moreover the homogeneity of cation configuration in he spinel structure was confirmed by X-ray diffraction analysis. The result of homogeneity of the spinel structural coincided with the analytical results of temperature dependence of magnetization. Furthermore, the influence of manganese oxide as starting material, on homogeneity of spinel structure was examined by using thermogravimetry-differential thermal analysis. It may be concluded that the reaction between $Mn_3O_4$ and Fe-Zn oxide mixture proceeds at fist in all combination of manganese oxide and oxie mixture, and then Mn-Zn-Fe spinel was formed.

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Tests for homogeneity of proportions in clustered binomial data

  • Jeong, Kwang Mo
    • Communications for Statistical Applications and Methods
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    • v.23 no.5
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    • pp.433-444
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    • 2016
  • When we observe binary responses in a cluster (such as rat lab-subjects), they are usually correlated to each other. In clustered binomial counts, the independence assumption is violated and we encounter an extra-variation. In the presence of extra-variation, the ordinary statistical analyses of binomial data are inappropriate to apply. In testing the homogeneity of proportions between several treatment groups, the classical Pearson chi-squared test has a severe flaw in the control of Type I error rates. We focus on modifying the chi-squared statistic by incorporating variance inflation factors. We suggest a method to adjust data in terms of dispersion estimate based on a quasi-likelihood model. We explain the testing procedure via an illustrative example as well as compare the performance of a modified chi-squared test with competitive statistics through a Monte Carlo study.

Low degree of homogeneity issue on the effective moduli of plain weave textile composites (기하학적 매개변수에 의한 평직복합재료의 저 균일도 문제)

  • 우경식;서영욱
    • Composites Research
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    • v.13 no.2
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    • pp.8-21
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    • 2000
  • In th is paper. the low degree of homogeneity issue in the effective modulus was studied for plain weave textile composites. Unit cell analyses were performed using multi-field macroelements. The effective moduli were calculated for finite and infinite configurations and the statistics assessment of the results was presented. Results indicated that the effective modulus of plain weave textile composites depended strongly on the fiber tow phase shift angles and the number of layers. As the number of layers increased, however, the distribution of the modulus showed concentration and higher degrees of homogeneity was attained.

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