• 제목/요약/키워드: homogeneity

검색결과 1,894건 처리시간 0.03초

Design of Crisscrossed Double-Layer Birdcage Coil for Improving B1+ Field Homogeneity for Small-Animal Magnetic Resonance Imaging at 300 MHz

  • Seo, Jeung-Hoon;Han, Sang-Doc;Kim, Kyoung-Nam
    • Journal of Magnetics
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    • 제20권3호
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    • pp.308-311
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    • 2015
  • We design a crisscrossed double-layer birdcage (DLBC) coil by modifying the coil geometry of a standard single-layer BC (SLBC) coil to enhance the homogeneity of transmitting magnetic flux density ($B_1{^+}$) along the main magnetic field ($B_0$)-direction for small-animal magnetic resonance imaging (MRI) at 300 MHz. The performance assessment of the crisscrossed DLBC coil is conducted by computational analysis with the finite-difference time domain method (FDTD) and compared with SLBC coil in terms of the $B_1$ and the $B_1{^+}$ distribution. As per the computational calculation studies, the mean value in the two-dimensional $B_1{^+}$ map obtained at the mid-axial slice with the proposed DLBC coil is slightly lower than that obtained with the SLBC coil, but the $B_1{^+}$ value of the DLBC coil in the outermost plane (40 mm away from the central plane) shows improvements of 19.3% and 24.8% over the SLBC coil $B_1{^+}$ value when simulating a spherical phantom and realistic mouse body modeling. These simulation results indicate that, the $B_1{^+}$ homogeneity along the z-direction was improved by using DLBC configuration. Our approach enables $B_1{^+}$ homogeneity improvement along the zdirection, and it can also be applied to ultra-high field (UHF) MRI systems.

주사제 사용을 위한 봉독의 균질성 및 안정성 평가 (Experimental studies of homogeneity and stability honeybee venom using ultra-high performance liquid chromatography)

  • 한상미;김세건;홍인표;우순옥;장혜리;이경우
    • 한국동물위생학회지
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    • 제39권2호
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    • pp.81-86
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    • 2016
  • Honeybee venom (BV) from Apis mellifera L. has been used as natural antimicrobial compounds in pigs, cows, dairy cattle and chicken farms in Korea. The purpose of this study was conducted to confirm homogeneity and stability of BV dissolved with distilled water or saline solution. Melittin was analyzed with ultra-high performance liquid chromatography (UPLC) for BV to secure the validation of analysis. BV at concentration of 1 mg/mL was dissolved with distilled water or saline solution at room temperature. Homogeneity of BV dissolved with distilled water or saline solution at upper, milddle, and lower layers all satisfied the accuracy and precision criteria. Stability of BV dissolved with distilled water or saline solution for 7 days all satisfied the criterion both light and dark storage condition. BV has satisfied with homogeneity and stability in distilled water or saline solution at room temperature under light or dark condition. The results of this study suggest that BV has a possibility as the substitute of natural antimicrobial agents for the animal drugs and feed additives.

교량 집단의 특성 수준간 통계적 응답 동질성 검정 및 다중 비교 분석 (Statistical Homogeneity Tests and Multiple Comparison Analysis for Response Characteristics between Treatments of Bridge Groups)

  • 황진하;김주한;안승수
    • 한국구조물진단유지관리공학회 논문집
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    • 제18권4호
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    • pp.107-117
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    • 2014
  • 본 연구는 실제 구조진단 사례에 기초하여 재료와 형식 및 공용기간에 따라 교량의 응답, 충격계수, 고유진동수 및 각 특성의 해석값/계측값 비 등에 관한 기술통계를 분석하고 주재료에 따른 T-검정과 구조형식 및 공용기간에 따른 분산분석을 통해서 요인 부집단 수준 간동질성 검정 및 다중비교분석을 수행하였다. 본 연구 결과는 응답 분포의 중심값, 산포도, 대칭성 등 통계적 특성 및 비교분석 집단 간 동질성 식별을 위한 참조값을 제공하며, 이것은 내하력 평가 등 구조 진단과 설계에서 엔지니어들이 취득한 계산 또는 계측값의 타당성을 비교검토하고 데이터베이스를 활용하는 등의 공학적 판단을 하는데 실제적으로 유용한 정보를 제공할 것으로 기대된다.

카드뮴 분석용 홍합(Mytilus coruscus) 표준물질의 균질성 및 안정성 시험평가 (Evaluation of Homogeneity and Stability of Korean Mussel (Mytilus coruscus) Standards for Cadmium Analysis)

  • 이하은;이장호;정다위;이수용;박기완;심규영
    • 한국환경과학회지
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    • 제28권11호
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    • pp.1041-1045
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    • 2019
  • In this study, the KS A ISO Guide 35 was applied to develop analytical standards for heavy metal cadmium using the Korean mussel (Mytilus coruscus) and to evaluate the homogeneity and stability of the sample. Some of the crucial characteristics that reference materials must consist include homogeneity and stability of both intra- and inter-bottles. We tested homogeneity using ANOVA analysis and short-term stability using regression analysis. The variations of cadmium concentrations did not significantly differ between intra- and inter-bottles (F=0.41, p=0.90). For short-term stability verification, cadmium analysis results were not statistically significant as a result of the regression analysis (significance F=0.51, p=0.53). This suggests that we can not dismiss the null hypothesis that there is no significant variation in concentrations of cadmium over time. These results indicated that the cryogenic-milling process has statistically proven the short-term stability for materials from mussels in the chemical analysis of cadmium. Therefore, we propose that the Korean mussel's reference material developed for the proficiency test could be used as a tool to evaluate reliability and consistency in laboratories.

BTEX 분석용 토양 숙련도 표준시료(PTMs) 개발에 관한 연구 (A Study on the Development of Soil-based PTMs for Analysis of BTEX)

  • 이민효;이군택;이법열;이원석;김금희;홍석영
    • 한국지하수토양환경학회지:지하수토양환경
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    • 제18권5호
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    • pp.15-25
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    • 2013
  • In this study, two kinds of soil-based proficiency testing materials (PTMs), NICE-012L and NICE-012R were prepared and certified for Benzen, Toluene, Etylbenzene and Xylene with evaluation of uncertainties. In order to analyse BTEX (Benzen Toluene Etylbenzene Xylene) for the candidate materials, GC/MS was used after pretreatment according to methods of soil analysis by Ministry of Environment. For the homogeneity test among bottles in terms of candidate materials, ISO 13528 and IUPAC Protocol were used and according to the result, both candidate materials showed sufficient homogeneity. Also, the stability test over the candidate materials was accessed according to the ISO Guide 35 by classifying short-term and long-term stability and the result showed that both candidate materials showed decent stability. The reference values of the two candidate materials depending on BTEX components were derived from the average of the 11 samples that were used for verification of the samples' homogeneity. Uncertainty of measurement was combined by uchar that was caused by a characteristic value, $u_{bb}$ that was caused by between-bottle homogeneity, and $u_{stab}$ that was caused by stability, and then combined uncertainty ($u_{PTM}$) was multiplied to the coverage factor (k) derived from the effective degree of freedom from each factor that leads to expanded uncertainty (U) in about 95% of confidence level. The proficiency testing materials developed through this study were supplied to National Institute of Environmental Research (NIER) and utilized as an external proficiency testing materials for evaluating analysis capacity of soil agencies with specialty in terms of soil analysis approved by Minister of Environment.

양성자치료시 Air Gap 변화에 따른 Lateral Penumbra와 선량분포 변화에 대한 비교 및 연구 (Research for Lateral Penumbra and Dose Distribution When Air Gap Changing in Proton Therapy Case)

  • 김재원;심진섭;장요종;강동윤;최계숙
    • 대한방사선치료학회지
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    • 제22권1호
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    • pp.47-51
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    • 2010
  • 목 적: 고 에너지 양성자치료에 있어서 Air gap (환자와 Beam 사출구 사이의 거리)의 변화는 Lateral Penumbra의 증가로 불필요한 조사야를 형성할 수 있고, 치료부위에서 최대선량 증가와 최소선량 감소로 선량분포의 균질성을 저하시킬 수 있다. 이에 Air gap 변화에 따른 선량분포에 대해 비교, 연구해 보고자 한다. 대상 및 방법: 본원에서 양성자치료를 받은 Lung, Liver 환자 6명을 선정하여 크기가 다른 조사야 A와 조사야 B에서 Air gap을 2, 4, 6, 8, 10 cm로 설정하여 Proton external beam planning system을 통해 치료계획을 세웠다. Air gap에 따른 Lateral Penumbra 영역 및 DVH (Dose Volume Histogram)를 비교하고 PCTV영역의 최대선량 및 최소선량 값을 비교하였다. 또한 PCTV내에 선량의 균질성을 알기 위하여 Homogeneity index값을 비교, 분석하였다. 결 과: 각각의 조사야에서 Air gap의 변화(2, 4, 6, 8, 10 cm)에 따른 Lateral Penumbra영역을 분석한 결과 조사야 A에서 Air gap 2~10 cm변화에 따라 평균 1.36~1.75 cm까지 약 28.7%가 지속적으로 증가하였고 조사야 B에서 평균 1.36~1.79 cm까지 약 31.6%가 지속적으로 증가하였다. DVH를 분석한 결과 최대선량의 상대선량 백분율은 Air gap 2~10 cm일 때 평균 108.1%에서 평균 110.3%까지 약 2.03%가 지속적으로 증가하였고 최소선량의 상대선량 백분율은 평균 93.9%에서 평균 90.8%까지 약 3.31%가 지속적으로 감소하였다. Homogeneity index값은 평균 Air gap 2~10 cm까지 1.09~2.6으로 2배 이상 증가하였다. 결 론: 양성자 치료에 있어서 Air gap이 증가함에 따라 Lateral Penumbra 영역이 증가함을 알 수 있었고, 치료부위에서 최대선량 값의 증가와 최소선량 값의 감소로 인하여 Homogeneity index값이 증가함으로써 PCTV내에 Beam의 균질성이 떨어지는 것을 알 수 있었다. 이에 추후 양성자치료시 Air gap을 줄이기 위한 노력이 필요할 것으로 사료된다.

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고균일 자계발생용 초전도 능동차폐 마그네트의 설계에 관한 연구 (A Design Approach for High Homogeneity Superconducting Magnet with Superconducting Active Shield)

  • 이광호;김성도;조윤현;이재복
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1996년도 하계학술대회 논문집 A
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    • pp.151-153
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    • 1996
  • An optimal design approach is presented for high homogeneity superconducting magnet with superconducting active shield especially for use in magnetic resonance imaging system. This paper is investigated phenomena for the stray magnetic field to get a basic reduction techniques of the unwanted stray magnetic field from the magnet. The present method obtains optimal coil configuration considering constraints for magnetic field homogeneity and leakage field.

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스피넬계 Mn-Zn 페라이트의 망간이온이 미치는 영향 (Behavior of Mn Ions in Spinel-type Mn-Zn-Fe Oxide System)

  • 권오흥
    • 자원리싸이클링
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    • 제9권5호
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    • pp.11-15
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    • 2000
  • The sample made of $Mn_3O_4$ indicated an excellent frequency dependency for intial permeability and core loss. Moreover the homogeneity of cation configuration in he spinel structure was confirmed by X-ray diffraction analysis. The result of homogeneity of the spinel structural coincided with the analytical results of temperature dependence of magnetization. Furthermore, the influence of manganese oxide as starting material, on homogeneity of spinel structure was examined by using thermogravimetry-differential thermal analysis. It may be concluded that the reaction between $Mn_3O_4$ and Fe-Zn oxide mixture proceeds at fist in all combination of manganese oxide and oxie mixture, and then Mn-Zn-Fe spinel was formed.

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Tests for homogeneity of proportions in clustered binomial data

  • Jeong, Kwang Mo
    • Communications for Statistical Applications and Methods
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    • 제23권5호
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    • pp.433-444
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    • 2016
  • When we observe binary responses in a cluster (such as rat lab-subjects), they are usually correlated to each other. In clustered binomial counts, the independence assumption is violated and we encounter an extra-variation. In the presence of extra-variation, the ordinary statistical analyses of binomial data are inappropriate to apply. In testing the homogeneity of proportions between several treatment groups, the classical Pearson chi-squared test has a severe flaw in the control of Type I error rates. We focus on modifying the chi-squared statistic by incorporating variance inflation factors. We suggest a method to adjust data in terms of dispersion estimate based on a quasi-likelihood model. We explain the testing procedure via an illustrative example as well as compare the performance of a modified chi-squared test with competitive statistics through a Monte Carlo study.

기하학적 매개변수에 의한 평직복합재료의 저 균일도 문제 (Low degree of homogeneity issue on the effective moduli of plain weave textile composites)

  • 우경식;서영욱
    • Composites Research
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    • 제13권2호
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    • pp.8-21
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    • 2000
  • 본 논문에서는 평직복합재료에 있어서 섬유다발의 위상각 변화와 적층수에 따른 등가탄성계수의 저 균일도 문제를 연구하였다. 각 적층수에 따라 단순히 적층된 모델과 무한히 반복되어 적층된 모델에 대해 단위구조 해석을 수행하였다. 수치실험을 통해 탄성계수를 계산하였고, 이를 통계적으로 처리하였다. 계산 결과 평직복합재료의 등가탄성계수는 위상각과 적층수의 변화에 크게 의존하며 임의의 조합에 대하여 그 분포양상은 큰 차이를 보였으나, 전반적으로 적층수가 증가함에 따라 균일도가 높아지는 경향을 보였다.

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