• Title/Summary/Keyword: hematological test

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Hematological test and treatment of cattle infected with theileriosis in Cheju area (제주도 타일레리아병 이환우의 혈액검사와 치료시험)

  • 김종성
    • Korean Journal of Veterinary Service
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    • v.19 no.2
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    • pp.180-184
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    • 1996
  • The present study was conducted to investigate for the hematological test and treatment effect of cattle infected with theileriosis in Cheju area. The results were summarized as fellows 1. Symptom of cattle infected with theileriosis were lose of appetite, depression, jaundise, anemia and fever. 2. A postmortem sing of cattle infected with theileriosis were not observed exept for jaundise of subcutaneous, expansion of gallbladder. 3. In the hematological test results of cattle infected with theileriosis supposed lese then killed so far as RBC number of 1, 000, 000/mm and if treated with RBC number of 2, 000, 000/mm cattle was able to recovery 4. In the treatment of cattle infected with theileriosis recovered after 90 days of treatment and the precaution against a shock of blood transfusion were able to the control of injection time and blood qantity.

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Survey for Antibodies to Bovine Leukemia Virus in Dairy Cattle (유우(乳牛) 백혈병(白血病)바이러스에 대(對)한 혈청항체(血淸抗體) 조사(調査))

  • Park, No-chan;Choi, Won-pil
    • Korean Journal of Veterinary Research
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    • v.26 no.1
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    • pp.61-68
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    • 1986
  • This paper described the distribution and transmissibility of BLV(bovine leukemia virus), the relationship between antibodies against BLV and lymphocyte count in 313 dairy cattle from 36 herds, the clinical signs and hematological findings of 2 lymphosarcomatous cattle in the northern area of Kyungpook. Eighty three (26.5%) of 313 cattle from 36 herds were positive for BLV antibodies and 19 (52.8%) of 36 herds were infected with BLV by the immunodiffusion test with BLV-gp antigen. The rate of BLV infection in cattle varied from 9.5 to 87.5% in 19 positive herds, it was higher in herds pastured during summer and included lymphosarcomatous onset than the other and also higher with the age. Eight (88.9%) out of 9 cattle which showed persistent lymphocytosis by the hematological test were positive for BLV antibodies. After 5 to 14 months, 13 (31.0%) of 42 cattle being negative for BLV antibodies in the positive herds converted into positive. Two lymphosarcomatous cattle were identified to be EBL (enzootic bovine leukemia) by the clinical sign, hematological examination and serological test.

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The Effects of Foot Massage on Fatigue and Depression among Patients with Hematological Malignancies (발마사지가 혈액 암 환자의 피로와 우울에 미치는 효과)

  • Sim, Mi Ja;Yoo, Yang Sook;Choe, Da Mi;Chung, Sang Ok;Jung, Jin;Jeon, Jin Yeong;Park, Jeong In;Eun, Bang Hee;Kim, Kwang Sung
    • Journal of Korean Clinical Nursing Research
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    • v.14 no.3
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    • pp.27-36
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    • 2008
  • Purpose: This study was to investigate the effects of foot massage on fatigue and depression among patients undergoing chemotherapy with hematological malignancies. Method: The subjects were 60 patients hospitalized for undergoing chemotherapy from September 2007 to March 2008, and 30 of them were the experimental group and the other 30 were the control group. To the subjects in the experimental group, foot massage was provided for 30 minutes everyday before the chemotherapy at the same time for 4 days, and the effect was measured on Day 4 and 5 after chemotherapy. Fatigue was measured using the Brief Fatigue Inventory (BFI) developed by Mendoza et al. (1999), and depression was measured by psychiatric rating scale SCL-90-R developed by Derogatis (1977) and translated by Kim Gwang il et al. The data were analyzed through $x^2$-test, Fisher's exact test, unpaired t-test and repeated measures ANOVA using SPSS 12.0. Results: Fatigue and depression were significantly lower in the experimental group than in the control group. Even on Day 5, fatigue and depression were significantly lower in the experimental group than in the control after finish foot massage. Conclusion: The findings of the study demonstrated that foot massage would be an effective nursing intervention to reduce fatigue and depression in patients with hematological malignancies.

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Presumptive Diagnosis of Mycoplasma pneumoniae Pneumonia in Children (소아에서 마이코플라즈마 폐렴의 예기적 진단)

  • Lee, Chang Eon;Park, Su Jin;Kim, Won Duck
    • Journal of Yeungnam Medical Science
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    • v.29 no.2
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    • pp.89-95
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    • 2012
  • Background: As Mycoplasma pneumoniae pneumonia has increased in Korea, its relevance to infants, toddlers, and adolescents has magnified as well as. However, it is difficult to perform the serological test and PCR test routinely for diagnosis in actual clinical practice. Thus, the authors conducted this study to help clinicians do presumptive diagnosis of Mycoplasma pneumoniae pneumonia using clinical, radiological, and hematological findings. Methods: The study population consisted of 224 children between 1 month and 14 years old, hospitalized for radiographically confirmed pneumonia. Patients were divided into two groups of 100 children with Mycoplasma pneumoniae pneumonia, as diagnosed using the ELISA method. Groups with negative result in Mycoplasma IgM antibody test were classified into the viral group (98 patients with respiratory virus) and the bacterial group (46 patients with the bacteria detected in the blood sputum culture or antibiotic treatment except macrolide improved the patient's condition). These groups were compared and analyzed using clinical, hematological, and radiographic differences and scoring system. Results: Clinical, hematological, and radiographic characteristics of Mycoplasma pneumoniae pneumonia have shown the intermediate level results between bacterial pneumonia and viral pneumonia. In terms of scoring system, the mean score of Mycoplasma pneumoniae pneumonia was 4.23, which was the intermediate level between bacterial pneumonia (mean score=6.67) and viral pneumonia (mean score=1.48). Conclusion: Results suggest that the combination of the scoring system information can increase the accuracy in the diagnosis even if they may have difficulties on diagnosis, because clinical manifestations, hematological, and radiographic findings are nonspecific.

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Subcutaneous Toxicity Study of Saposhnikovia divaricata (Turcz.) Schischk in Rats (랫드에서 방풍, Saposhnikovia divaricata (Turcz.) Schischk의 피하투여 독성에 대한 연구)

  • 이영순;조성대;안남식;정지원;양세란;박준석;박기수;홍인선;서민수
    • Toxicological Research
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    • v.19 no.1
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    • pp.73-82
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    • 2003
  • To evaluate influence of Saposhnikovia divaricata (Turcz.) Schischk extract on rat, Saposhnikovia divaricata (Turcz.) Schischk extract was diluted with 0.9% saline (100 mg/ml/kg, 10 mg/ml/kg, and 1 mg/ml/kg, respectively), and each of diluted test material extract was daily treated subcutaneously for 4 weeks and single-treated subcutaneously for 2 weeks. There were no significances in body weight analysis, urinary analysis, and ophthalmological test. However, in serum biochemical analysis and hematological analysis, we found some significances in high and middle dose group compared with control group. These significances in serum biochemical analysis and hematological analysis may be not induced by test material, because it was not found to be significant from control group in histopathological examination. Therefore, it was concluded that NOEL (No Observed Effect Level) of test material extract may be higher than all treatment doses used in this study, and Saposhnikovia divaricata (Turcz.) Schischk extract may be a non-toxic material.

Effect of Cynanchi wilfordii Radix Extract on the Acute Toxicity in Mice and Subacute Toxicity in Rats (백수오(白首烏) 엑스의 마우스 급성독성(急性毒性) 및 흰쥐 아급성독성(亞急性毒性)에 미치는 영향(影響))

  • Chung, Eun-Jin;Lee, Byung-Joo;Chung, Myung- Hyun
    • Korean Journal of Pharmacognosy
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    • v.24 no.2
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    • pp.166-176
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    • 1993
  • This study was attempted to investigate the acute toxicity in mice, the subacute toxicity in rats of Cynanchi wilfordii Radix extract, the effect on transaminase activities, hematological parameters, leukocyte parameters in serum of subacute-toxicated rats. In acute toxicity test, the death rate was not observed in 50, 100, 200, 300 mg/kg(i.p.), one tenths to two tenths in 300, 500, 1000, 1500 mg/kg(p.o.) for two weeks. In subacute test, rats were all died in 300 mg/kg(p.o.) during 4 weeks, in 500, 1000 mg/kg(p.o.) during three weeks. The cause of death believed to be stomach ulcer. The activities of S-GOT and S-GPT were significantly increased in all sample-treated groups, when compared with the normal groups. A number of WBC and neutrophil belong to hematological parameter were significantly increased, lymphocyte was decreased in all sample-treated group, when compared with normal group. The hemolytic action on water extract, saponin and alcohol extract showed very low activities.

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Effects of brown rice-vegetable school meal program on subjective health status, BMI and hematological parameters among high school students (청소년 대상의 현미-채식 급식 프로그램이 주관적 건강상태, BMI 및 혈액지표에 미치는 효과)

  • Moon, Kyoung-Ja;Kim, Hye-Young
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.11
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    • pp.7385-7393
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    • 2015
  • This study aimed to identify the effect of brown rice-vegetable school meals program on the subjective health status, BMI and hematological parameters of high school students. This is a single group pre-post study design that includes 17 high school boys and 18 high school girls. Students were catered for lunch and dinner with brown rice and a vegetarian diet for 12 weeks at the school. The collected data on subjective health status, BMI levels and hematological parameters were measured in pre and post, and changes were compared by paired t-test. Subjective health status of the participants has improved and BMI was reduced. Blood Hct, Hb, Hct, total protein and albumin have also been reduced. Ca and triglyceride levels decreased in females. However, all levels were reduced within the normal range. These results show that brown rice-vegetable intake of high school students reduces weight and helps them prevent from acquiring cardiovascular diseases in adulthood through the reduction of serum triglyceride and in practicing healthy eating habits.

Effects of ultraviolet light B irradiation on nitric oxide activity in the sprague-dawley rat in vivo (I) (흰쥐에 조사한 자외선B가 Nitric Oxide의 활성에 미치는 효과 (I))

  • Min, Kyung-Ok;Kim, Jung-Hwan
    • Journal of Korean Physical Therapy Science
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    • v.6 no.3
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    • pp.63-82
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    • 1999
  • Recent studies have revealed that Nitric oxide(NO) was one of the demonstration for the physiological regulator, endothelial derived relaxing factor(EDRF) and that NO was produced by ultraviolet irradiation in human. Thus, the present author have carried out a experimental study on the change of hematological, histological value of ultraviolet irradiation in sprague-dawley rats. The subjects were divided into four groups of ten rats each selected at random. There were 4 groups: 1. no irradiation control; 2. ultraviolet $75mJ/cm^2$ irradiation group; 3. ultraviolet $150mJ/cm^2$ irradiation group; 4. ultraviolet $225mJ/cm^2$ group. After a irradiation, hematological and histological tests were performed to observe erythrocyte, hemoglobin, hematocrit, MCH, MCHC, MCV, $O_2$ saturation, pH, $PO_2,\;PCO_2$ value and to observe histological changes. In hematological tests, erythrocyte, hemoglobin, hematocrit significantly increased in $75mJ/cm^2$ than control group and more $150mJ/cm^2$ ultraviolet irradiation group respectively. Also In blood gas tests, $PO_2$ significantly increased in $75mJ/cm^2$ and more $150mJ/cm^2$ group than control group. Whereas $PCO_2$ significantly decreased in $75mJ/cm^2$ and more $150mJ/cm^2$ group than control group (Duncan-Tukey test, P<0.05). In histological tests, control and $75mJ/cm^2$ group unchanged, but more $150mJ/cm^2$ group changed that it was cytolysis, cytotoxic effect, acanthosis, proliferation of keratinocyte, appearance of amorphous cell and pyknotic nucleus, production of sunburn cell. In conclusion, the present author results support the importance of the relation between NO effect and hematological, histological value by ultraviolet B irradiation.

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T-SPOT.TB for Detection of Tuberculosis Infection among Hematological Malignancy Patients and Hematopoietic Stem Cell Transplant Recipients

  • Qin, Li-Li;Wang, Qin-Rong;Wang, Qian;Yao, Hong;Wen, Li-Jun;Wu, Li-Li;Ping, Na-Na;Xie, Jun-Dan;Chen, Mei-Yu;Chen, Su-Ning
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7415-7419
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    • 2013
  • The diagnosis of latent Mycobacterium tuberculosis infection (LTBI) is recommended in hematological malignancy patients and before hematopoietic stem cell transplantation (Guidelines for the prevention and management of infectious complications of solid organ transplantation, 2004). Compared to traditional methods such as tuberculin skin test (TST), T-SPOT.TB has been shown to be more specific. In the present study we enrolled 536 patients for whom T-SPOT.TB was performed, among which 295 patients also received the TST test. The agreement (79%) between T-SPOT.TB and TST was poor (x=0.274, P<0.001). The patients with positive T-SPOT.TB results numbered 62 (11.6%), in which only 20 (48.8%) of the 41 receiving the TST test had positive results. A majority of the patients with T-SPOT.TB positive results had some other evidence ofTB, such as TB history, clinical symptoms and an abnormal chest CT scan. Active TB was found in 9 patients, in which 2 had negative TST results. We followed up the patients and no one developed active TB. Our study suggested that the T-SPOT.TB may be more useful for screening LTBI and active TB in hematological malignancy patients and hematopoietic stem cell transplant recipients than the TST test.

Investigation of canine dirofilariasis and brucellosis in free roaming dogs from public animal shelters in Gwangju area (광주지역 동물보호소내 유기견의 개심장사상충과 개 브루셀라병 감염 실태조사)

  • Koh, Ba-Ra-Da;Na, Ho-Myung;Jang, Mi-Sun;Kim, Ji-Yeon;Park, Seong-Do
    • Korean Journal of Veterinary Service
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    • v.30 no.1
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    • pp.155-164
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    • 2007
  • This study was conducted to investigate the prevalence of canine heartworm infections, canine brucellosis and hematologic values from 153 free roaming dogs in the area of Gwangju city from March to November 2006. Nineteen (12.4%) of 153 samples tested with modified Knott's technique showed positive reaction for microfilariae. Polymerase chain reaction using specific primers for D immitis amplified the expected product from all samples of 19 microfilaremic canine blood samples as determined by the modified Knott's test for microfilariae. The seasonal infection rates of microfilariae were higher in the spring season (10/19, 52.6%) than in the other seasons. The major hematological findings in microfilaremic dogs were mild leukocytosis and mild monocytosis. A total of 100 dogs randomly selected from 153 free roaming dogs were negative for canine brucellosis by serological test using immunochromatographic antibody test kit.