• The Korean Journal of Community Living Science
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• v.25 no.1
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• pp.19-27
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• 2014

This study investigates drinking attitudes and behaviors of university students. The sample included 355 students living in Busan, Korea. The questionnaire addressed general background information (gender, age, grade and monthly pocket money), drinking attitudes (understanding the effects of alcohol on the body, stereotype of drink, age at the first drink, the drinking companion at the first drink, reasons for starting to drink, main drinking companions, major reasons for drinking, the history of drinking alone, and reasons for drinking alone), drinking behaviors (the cost of each drinking occasion, drinking amounts, the frequency of drinking, the frequency of heavy drinking, the type of alcoholic beverage, and the places of drinking). A few respondents (both male and female students) started drinking while in high school (p<0.05), and most respondents drank with friends (males: 91.0%, female: 92.2%). The main reasons for drinking were the mood for male student (46.3%) and relationships for female student (49.1%) (p<0.05). Male respondents consumed more than seven glasses of soju (39.9%), whereas female respondents, five to seven glasses (49.7%) (p<0.05). On average, the respondents drank one to two times a week (males: 47.9%, females: 51.5%) and experienced heavy drinking one to three times every three months (males: 19.1%, females: 21.0%) (p<.05). The results suggest that students with frequent alcohol consumption and heavy alcohol dependence are likely to face problems and thus require aggressive intervention strategies that target them specifically.

• Korean Journal of Biological Psychiatry
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• v.13 no.4
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• pp.273-278
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• 2006

Objectives : Biochemical markers can provide an objective evidence of heavy alcohol drinking. The purpose of this study was to compare and evaluate the usefulness of biological markers detecting alcohol dependence, such as mean corpuscular volume(MCV), gamma-glutamyl transferase(GGT), and carbohydrate-deficient transferrin(CDT) in the patients of an alcohol counseling center. Methods : This study was done with 64 patients with alcohol dependence and 36 healthy subjects. Relative values(%) of CDT were determined in their sera with turbidimetric immunoassay(Bio-Rad %CDT assay, Axis-Shield ASA, Oslo, Norway), and were compared with conventional markers of alcohol consumption, GGT and MCV. Results : Among the patients with alcohol dependence, 78.1% showed abnormal %CDT levels compared with GGT(61.9%) and MCV(20.7%). The areas under the receiver operating characteristic(ROC) curves(95% confidence interval) for %CDT, GGT, and MCV were 0.934(0.866-0.973), 0.871(0.789-0.930), and 0.575 (0.472-0.673), respectively. Conclusion : %CDT seems to be the most reliable biological marker for the detection and monitoring of alcohol consumption in the patients with alcohol dependence of the alcohol counseling center.

• Korean Journal of Adult Nursing
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• v.17 no.1
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• pp.68-76
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• 2005

Purpose: The purpose of the study was to investigate the level of cigarette smoking and alcohol consumption in men with Diabetes Mellitus and to examine the relationships among those variables. Method: The subject consisted of 152 adult men with diabetes mellitus. Q-F methods and FTQ was used to measure the level of alcohol consumption and nicotine dependency. The amount of smoking was measured by the number of cigarette packs used per week. Results: Prevalence of drinking was 63.6% and in the current drinkers, 34.4% were heavy drinkers. The prevalence of cigarette smoking was 36.2% with a mean of 6.03 packs per week. Twenty percent of the smokers were dependent on nicotine. Subjects who had complications or other diseases drank alcohol more than who had not. There was a positive relationship between the level of smoking and nicotine dependency. Conclusion: Alcohol drinking and cigarette smoking is a serious health problem in men with diabetes. It is necessary to have an educational approach for controlling drinking and smoking in diabetes patients.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3675-3679
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• 2014

We assessed the association between frequency of heavy binge drinking and mortality from oropharynx and esophagus cancer after controlling for the total volume of alcohol intake among Korean men. The cohort comprised 2,677 male residents in Kangwha County, aged 55 or older in March 1985, for their upper digestive tract cancer mortality for 20.8 years up to December 31, 2005. For daily binge drinkers versus non-drinkers, the hazard ratios (95% Cls) for mortality were 4.82 (1.36, 17.1) and 6.75 (1.45, 31.4) for oropharyngeal and esophageal cancers, respectively. Even after adjusting for the volume of alcohol intake, we found the hazard ratios for frequency of binge drinking and mortality of oropharyngeal or esophageal cancer to not change appreciably: the hazard ratios were 4.90 (1.00, 27.0) and 7.17 (1.02, 50.6), respectively. For esophageal cancer, there was a strong dose-response relationship. The frequency of heavy binge drinking and not just the volume of alcohol intake may increase the risk of mortality from upper digestive tract cancer, particularly esophageal cancer in Korean men. These findings need to be confirmed in further studies with a larger sample size.

• Journal of Life Science
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• v.5 no.3
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• pp.145-150
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• 1995

Alcoholic liver disease is defined by the development of three types of liver damage following chronic heavy alcohol consumption, namely, alcoholic fatty liver, alcoholic hepatitis, and alcoholic cirrhosis, The clinical features and laboratory tests often do not distinguish among these types of liver injuries. In addition, a considerable number of the patients who have clinical and laboratory features compatible with alcoholic liver disease are diagnosed on liver biopsy to have chronic viral hepatitis or other lesion. Because of these factors, liver biopsy is frequently needed to arrive a definite diagnosis of the disease, its activity, and its chronicity. Fatty liver is usually a benign and reverible condition that disappears on abstinence from alcohol. However, alcoholic hepatitis is usually regarded as a precursor of cirrhosis. The principle factors in the development of alcoholic hepatitis and cirrhosis are the quantity and length of ingestion of alcohol. women are much more susceptible than men to hepatic injuries. Since only 10 - 20% of alcoholics develop cirrhosis, however, it is conceivable that other factors, either genetic, environmental, or nutritional may contribute in the genesis of liver injuries. The most important factor in the treatment of alcoholic liver disease is prolonzed abstinence from alcohol, since abstinence by itself improves clinical status and survival, Nutritional support in patients with nutritional deficiency, and specific drug therapies such as corticosteroid or anabolic steroids for hospitaliged patients with severe alcoholic hepatitis also play an important role in devreasing morbidity and improving survival. Liver transplantation is a newer treatment modality in the patients with advanced cirrhosis, not responsible to medical treatment.

• Journal of Preventive Medicine and Public Health
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• v.35 no.2
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• pp.123-128
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• 2002

Objective : To examine the relationship between cigarette smoking, alcohol and cancer mortality in men in the Kangwha cohort after 12 years and 10 months of follow up. Methods : The subjects consisted of 2,681 men in the Kangwha cohort aged over 55 in 1985. Number of deaths and the time to death front all cancers and other cause were measured and the data for the smoking and drinking habits were obtained from the baseline survey data in 1985. All subjects were categorized into four groups according to their smoking habits: non-smokers, ex-smokers, mode(ate-smokers (1-19 cigarettes per day), heavy-smokers ($\geq$20 cigarettes per day). In addition, they were also categorized according to their drinking habits: non-drinkers, light-drinkers ($\leq$1 drink per week), moderate-drinkers (<3 drinks per day), heavy-drinkers ($\geq$3 drinks per day). The cancer specific death rates were calculated according to their smoking and drinking status. The adjusted risk ratio for all cancer deaths according to their smoking and drinking status were estimated using the Cox's proportional hazard regression model. Results : Using nonsmokers as the reference category, the adjusted risk ratio for all cancer deaths were 1.573(95% CI=1.003-2.468) for heavy-smokers. For lung cancer deaths, the adjusted risk ratios were 3.540(95% CI=1.251-10.018) for moderate-smoker and 4.114(95% CI=1.275-13.271) for heavy-smokers. Compared to non-drinkers, the adjusted risk ratio for stomach cancer was 2.204(95% CI=1.114-4.361) for light-drinkers. Conclusion : Smoking is the most significant risk factor for cancer deaths particularly lung cancer.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.5
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• pp.3323-3332
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• 2015

The purpose of this study was to investigated the effects of alcohol intake on blood pressure, serum lipids, liver function tests and obesity indices in middle-aged male workers. The 2,175 male workers aged 30-59 years who examined health checkup were recruited as the study subjects during the period between January to December, 2013. We observed the relationships between the amount of alcohol intake and blood pressure, serum lipids, liver function tests and obesity indices. As a result, the mean score of SBP, DBP, LDL-C and TG were significantly higher increasing with amount of alcohol increased, but HDL-C were significantly lower increasing with amount of alcohol increased. AST, ALT, ALP and ${\gamma}$-GTP were significantly higher increasing with amount of alcohol increased, but obesity indices were not significant. Age adjusted odds ratios(ORs) increasing with abnormal levels of SBP, DBP, HDL-C, LDL-C, TG, AST and ALT were significantly increased in heavy drinking group than light drinking group. Above results suggested that the heavy drink related with blood, serum lipid levels and liver function test levels, but not find out with obesity indices.

• Journal of Nutrition and Health
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• v.32 no.5
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• pp.570-576
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• 1999

This study was carried out to examine the effects of alcohol on serum lipid levels. Subjects of this study were 50 military officers living in Honsung, Korea, 25 of whom consumed alcohol on a regular basis and 25 of whom did not. All subjects were previously informed of the purpose of the study and the methods of food intake reporting and blood testing. The age distribution range of subjects was 30-49 years. Weight, height, and body mass index(BMI) were not significantly different between the two groups. Blood pressure was compared, and it was found that the drinker group had mean systolic(SBP) and diastolic blood pressures(DBP) 10mmHg higher than the non-drinker group. Nutrient intake levels of the two groups were not significantly different and were adequate with respect to the recommended dietary allowances. It was found that the drinker group ingested more calories, protein, fat and vitamn B1 than the non-drinker group, while the non-drinker group ingested more carbohydrate, calcium, iron, vitamin A, niacin and ascorbic acid. These differences were believed caused by increased caloric intake from alcohol and additional intake of meat served with drinks for the drinking group. Fourteen of the twenty-five drinkers(56%) had drank regularly for five to ten years. Most drinkers drank 2-3 times per week, with alcohol intake less than two bottles(720ml)of distilled liquor(Soju) at a time. Meat was often served with alcohol as reported by 72% of the drinker group, and was believed to contribute to raised intake of calories, protein and fat in this group. Serum lipid levels of both groups were classified as normal, but the components of total cholesterol, triglycerides were significantly higher in drinkers than non-drinkers. The correlation between triglyceride levels and alcohol intake at one sitting was shown to be significantly positive(r=0.57, p<0.01), so it was believed that triglyceride elevation was associated more with heavy drinking than light drinking. We can conclude that if alcohol is consumed with a normal diet, then serum cholesterol, triglyceride and total lipid levels are expected to increase.

• Journal of Nutrition and Health
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• v.39 no.6
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• pp.572-584
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• 2006

The purpose of this study was to compare the nutrient intake and diet quality of male college student according to smoking groups. Subjects were recruited and divided into three groups according to the smoking, which included non-smoker (n = 100), light-smoker (n = 78; packyear < 5), and heavy-smoker (n = 76; packyear ${\geq}$ 5). Subjects were interviewed using a general questionnaire, 24-hour recall method for dietary intake and diet quality. The average age of the subjects were 22.7 years for non-smoker, 23.5 years for light-smoker, and 23.4 years for heavy-smoker. Also the results showed that the heavy-smoker was significantly more often to drink coffee and alcohol compared with the other two groups (p<0.001, p<0.05). The mean daily energy intake was 2278.1 kcal in non-smoker, 2148.3 kcal in light-smoker, and 2144.4 kcal in heavy-smoker. The heavy-smoker consumed significantly lower intakes of vitamin C (p<0.001), calcium (p<0.01), animal calcium (p<0.01), and potassium (p<0.05) compared to the non-smoker and light-smoker. Also NAR (Nutrient Adequacy Ratio), ND (Nutrient Density), and INQ (Index of Nutritional Quality) of these nutrients in heavy-smoker were lower than the other two groups. Mean adequacy ratio (MAR) was 0.78 in non-smoker, 0.78 in light-smoker, and 0.74 in heavy smoker (p<0.05). The heavy-smoker consumed significantly lower intakes of fruits (p<0.001) compared to the non-smoker and light-smoker. The DVS (Dietary Variety Score) of heavy-smoker (26.8) was significantly lower than that 30.4 of non-smoker and 31.5 of light-smoker (p<0.01). In conclusion, heavy-smoker man have low intake status of vitamin C, calcium and potassium, and partly low diet quality. Therefore it was needed that well planed diet to replace the nutrients supplied from excluded food groups in heavy- smoker.

• Journal of applied mathematics & informatics
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• v.31 no.1_2
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• pp.1-25
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• 2013

In this paper we have developed a mathematical model of alcohol abuse. It consists of four compartments corresponding to four population classes, namely, moderate and occasional drinkers, heavy drinkers, drinkers in treatment and temporarily recovered class. Basic reproduction number $R_0$ has been determined. Sensitivity analysis of $R_0$ identifies ${\beta}_1$, the transmission coefficient from moderate and occasional drinker to heavy drinker, as the most useful parameter to target for the reduction of $R_0$. The model is locally asymptotically stable at disease free or problem free equilibrium (DFE) $E_0$ when $R_0$ < 1. It is found that, when $R_0$ = 1, a backward bifurcation can occur and when $R_0$ > 1, the endemic equilibrium $E^*$ becomes stable. Further analysis gives the global asymptotic stability of DFE. Our aim of this analysis is to identify the parameters of interest for further study with a view for informing and assisting policy-makers in targeting prevention and treatment resources for maximum effectiveness.