Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
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Cigarette Smoking, Alcohol and Cancer Mortality in Men: The Kangwha Cohort Study

흡연과 음주가 남성 암 사망에 미치는 영향: 강화 코호트 연구

  • Lee, Sang-Gyu (Department of Preventive Medicine and Public Health, College of Medicine, Yonsei University) ;
  • Nam, Chung-Mo (Department of Preventive Medicine and Public Health, College of Medicine, Yonsei University) ;
  • Yi, Sang-Wook (Department of Preventive Medicine, College of Medicine, Kwandong University) ;
  • Ohrr, Hee-Chul (Department of Preventive Medicine and Public Health, College of Medicine, Yonsei University)
  • 이상규 (연세대학교 의과대학 예방의학교실) ;
  • 남정모 (연세대학교 의과대학 예방의학교실) ;
  • 이상욱 (관동대학교 의과대학 예방의학교실) ;
  • 오희철 (연세대학교 의과대학 예방의학교실)
  • Published : 2002.06.01
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Abstract

Objective : To examine the relationship between cigarette smoking, alcohol and cancer mortality in men in the Kangwha cohort after 12 years and 10 months of follow up. Methods : The subjects consisted of 2,681 men in the Kangwha cohort aged over 55 in 1985. Number of deaths and the time to death front all cancers and other cause were measured and the data for the smoking and drinking habits were obtained from the baseline survey data in 1985. All subjects were categorized into four groups according to their smoking habits: non-smokers, ex-smokers, mode(ate-smokers (1-19 cigarettes per day), heavy-smokers ($\geq$20 cigarettes per day). In addition, they were also categorized according to their drinking habits: non-drinkers, light-drinkers ($\leq$1 drink per week), moderate-drinkers (<3 drinks per day), heavy-drinkers ($\geq$3 drinks per day). The cancer specific death rates were calculated according to their smoking and drinking status. The adjusted risk ratio for all cancer deaths according to their smoking and drinking status were estimated using the Cox's proportional hazard regression model. Results : Using nonsmokers as the reference category, the adjusted risk ratio for all cancer deaths were 1.573(95% CI=1.003-2.468) for heavy-smokers. For lung cancer deaths, the adjusted risk ratios were 3.540(95% CI=1.251-10.018) for moderate-smoker and 4.114(95% CI=1.275-13.271) for heavy-smokers. Compared to non-drinkers, the adjusted risk ratio for stomach cancer was 2.204(95% CI=1.114-4.361) for light-drinkers. Conclusion : Smoking is the most significant risk factor for cancer deaths particularly lung cancer.

Keywords

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