• Korean Journal of Clinical Laboratory Science
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• v.40 no.2
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• pp.86-93
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• 2008

This study was performed to investigation of the serum alpha-fetoprotein (AFP) levels in healthy adults. A total of 2,160 (male 1,415, female 745) health checkup adults were examined for AFP levels by chemiluminescence immunoassay (CLIA) method, during the period from September, 2007 to August, 2008. The mean serum AFP level was 2.168 (0.605~20.35) ng/mL, and it was 2.309 (0.605~20.35) ng/mL in male, 1.906 (0.605~10.36) ng/mL in female, respectively. 1,816 (male 1,109, female 709) healthy adults were screened for the absence of viral hepatitis and normal alanine amino transferase (ALT) levels. The mean serum AFP level of healthy adult was 2.041 (0.605~7.83) ng/mL, and it was 2.181 (0.605~7.83) ng/mL in male, 1.822 (0.605~6.55) ng/mL in female, respectively. Serum AFP increased with age group, there was a higher level in male compared to female. These results suggests that the use of reference value of AFP in healthy adults in the Jeonbuk. With the reference value now defined, it becomes possible to compare levels in different populations.

• Journal of Preventive Medicine and Public Health
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• v.21 no.1 s.23
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• pp.89-98
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• 1988

While there have been not a few reports on the seroepidemiological characteristics of hepatitis B virus (HBV) infection in Korea, most of them, however, have had several limitations; operational definition of HBV infection, validity of detection methods of HBV serologic markers, size of the study population, and confirmation of the vaccination history against HBV, etc. In order to avoid such limitations, authors randomly selected 1,495 healthy adults among the 217,511 insured (target population) of Korean Medical Insurance Corporation, living in seoul, and tested HBV serologic markers by RIA method and conducted direct interview to them. Although HBV serologic markers (HBsAg, anti-HBs and anti-HBc) of all the subjects were tested, 392(26.2%) of interview failure cases and 361 vaccinee were excluded from the actual population. Finally, the serologic markers tested of 742 nonvaccinee (study population) only were analysed for the seroepidemiologic observation of the natural infection of HBV. The seroepidemiological characteristics of HBV infection in Korea were as follows ; 1. Point prevalence of HBs antigenemia was 11.7(9.1{\sim}14.3)% in male, which was slightly higher than that of female, 9.5($3.7{\sim}15.3$)%. This level was one of the highest among those of Asian-Pacific countries. Decreasing tendency of HBsAg prevalence alter the age of 50 was observed, which seems to be due to selective attrition of HBV chronic carriers among the healthy adults and/or to the limited-lasting duration of the HBs antigenemia, in part. 2. Point prevalence of anti-HBc(78.8% in male,50.9% in female) was higher than that of anti-HBs(65.2% in male,46.6% in female), respectively. And both of them were higher in male than in female. Increasing tendency of the prevalence of both antibodies was observed by age, which seems to be largely due to recurrent infection in adults and to some cumulative effect, in part, of their relatively longer-lasting duration. 3. The level of HBV infection defined by positive for at least one of the 3 serologic markers of HBV by RIA method was 84.7($81.8{\sim}87.6$)% in male and 61.2($51.9{\sim}70.5$)% in female, which was also one of the highest among those of Asian-Pacific countries. The proportion of susceptible population to HBV infection among healthy adults was 15.3% in male and 38.8% in female. 4. The relative frequency of current or past infection and chronic carrier among HBV infected person was estimated. The currently or past infected was estimated 75.7% in male and 71.8% in female, and chronic carrier state, 13.8% in male and 14.1% in female. The analysis of the geometric mean of the antibody titer in anti-HBs positive sera indicated also to be compatible with the above findings, suggesting that active, even though inapparent, infection of HBV occur so frequently among healthy adults in Korea.

• Physical Therapy Rehabilitation Science
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• v.9 no.3
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• pp.155-164
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• 2020

Objective: This study aimed to compare muscle structure, balance, and gait parameters between healthy adults and persons with stroke and to analyze the correlation among these variables. Design: Cross-sectional study. Methods: Twenty persons with stroke (11 male, 9 female) and twenty healthy participants (9 male, 11 female) were included. Ultrasound images of the triceps surae and the tibialis anterior were acquired in sitting resting, sitting co-contraction, and standing resting positions and also during the functional reach test (FRT) and single leg anterior reaching test (SLART). Muscle thickness and fascicle length were measured. Spatiotemporal parameters of gait were measured using a pressure walkway. Gait speed, cadence, step length, stride length, stance time, and swing time were measured. Results: Changes in percent fascicle length were significantly greater in the gastrocnemius and soleus (SOL) muscles of healthy adults in the sitting co-contraction position (p<0.05). The percent fascicle length of the SOL in FRT and SLART were significantly greater in healthy adults (p<0.05). The mid-stance phase of stroke patients was shorter than healthy adults (p<0.05). A negative correlation was observed between percent fascicle length of the SOL in the sitting co-contraction position and the proportion of the mid-stance phase (p<0.05). Conclusions: The function of the triceps surae is affected in persons with stroke when compared with healthy adults. This can lead to difficulty in performing tasks that involve forward transfer of weight. If the triceps surae is not sufficiently secured, the possibility of compensation in the stance phase increases during gait.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.8
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• pp.3513-3520
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• 2012

This study aimed to investigate the difference of the body orientation ability in sitting position to adapt to dynamically changing angle of the base of support in stroke patients and Healthy adults. The angle between vertical and head and trunk in 12 stroke patients (6 male and 6 female) and 12 healthy adults (6 male and 6 female) were measured by video motion analysis system. The head and trunk angle between stroke patients and healthy adults in sitting position were significantly different when increase the angle of dominant side(p<.05). The head and trunk angle between stroke patients and healthy adults in sitting position were significantly different when increase the angle of non-dominant side(p<.05). The head and trunk angle between stroke patients and healthy adults in sitting position were significantly different when decrease the angle of non-dominant side(p<.05). The head angle between stroke patients and healthy adults in sitting position was significantly different(p<.05), but the trunk angle was not significantly different when decrease the angle of dominant side(p>.05), Stroke patients compared to healthy adults had more deficits in their body orientation ability in sitting position to adapt to dynamically changing angle of the base of support. This finding may help to understand postural control deficits more clearly in stroke patients in sitting position.

• Journal of Preventive Medicine and Public Health
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• v.47 no.2
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• pp.113-123
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• 2014

Objectives: Several previous studies have found that healthy behaviors substantially reduce non-communicable disease incidence and mortality. The present study was performed to estimate the prevalence of four modifiable healthy behaviors and a healthy lifestyle among Korean adults according to socio-demographic and regional factors. Methods: We analyzed data from 199 400 Korean adults aged 19 years and older who participated in the 2010 Korean Community Health Survey. We defined a healthy lifestyle as a combination of four modifiable healthy behaviors: non-smoking, moderate alcohol consumption, regular walking, and a healthy weight. We calculated the prevalence rates and odds ratios of each healthy behavior and healthy lifestyle according to socio-demographic and regional characteristics. Results: The prevalence rates were as follows: non-smoking, 75.0% (53.7% in men, 96.6% in women); moderate alcohol consumption, 88.2% (79.7% in men, 96.9% in women); regular walking, 45.0% (46.2% in men, 43.8% in women); healthy weight, 77.4% (71.3% in men, 73.6% in women); and a healthy lifestyle, 25.5% (16.4% in men, 34.6% in women). The characteristics associated with a low prevalence of healthy lifestyle were male gender, younger age (19 to 44 years of age), low educational attainment, married, living in a rural area, living in the Chungcheong, Youngnam, or Gwangwon-Jeju region, and poorer self-rated health. Conclusions: Further research should be implemented to explore the explainable factors of disparities for socio-demographic and regional characteristics to engage in the healthy lifestyle among adults.

• Journal of Nutrition and Health
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• v.36 no.7
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• pp.720-728
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• 2003

This study was conducted to evaluate changes in plasma concentration and urinary excretion of carnitine, as well as plasma lipid level and fatty acid composition, caused by short term supplementation of carnitine in humans. Ten healthy male subjects (21.2 $\pm$ 0.5 years old) received oral carnitine supplementation (4 g/day) as tablets for two weeks. Fasting blood and random urine samples were collected from each subject both prior to and at the end of carnitine supplemention program. Following the 2 weeks of carnitine supplementation, plasma total carnitine (TCNE) concentration increased 20% (85.1 $\pm$ 7.4 vs 67.3 $\pm$ 9.1 $\mu$ mol/1, p> 0.05), while urinary excretion of total carnitine increased ten times compared to the value measured prior to the supplementation (3051 $\pm$ 692 vs 278 $\pm$ 90.1 $\mu$ mol/g creatinine, p < 0.01). Non-esterified carnitine (NEC) comprised from 71 to 88% of TCNE in plasma, and from 32 to 40% of TCNE excreted in the urine. Two weeks of carnitine supplementation in healthy adults significantly elevated plasma level of acid soluble acylcarnitine (ASAC) which is esterified mostly with short chain fatty acids (21.6 $\pm$ 1.6 $\mu$ mol/l) compared to the value measured prior to the supplementation (6.4 $\pm$ 0.8 $\mu$ mol/l) (p < 0.05). Carnitine supplementation significantly increased plasma HDL-cholesterol level (p < 0.05), and decreased the atherogenic index (p < 0.05), but failed to cause any significant change in plasma levels of total cholesterol, triglyceride, and free fatty acids. Plasma triglyceride and phospholipid fatty acid compositions were not significaly affected as well by the oral supplementation of carnitine in subjects with normal range of blood lipid levels.

• Korean Journal of Exercise Nutrition
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• v.23 no.2
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• pp.16-21
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• 2019

[Purpose] The purpose of this study was to comparatively investigate the correlation among body composition, resting metabolic rate (RMR), and physical activity (PA) between young and middle-aged Korean adults. [Methods] A total of 53 [male n=23, female n=30] subjects were included in this study, among whom 34 subjects were healthy young adults [male n=18, female n=16] and 19 were middle-aged adults [male n=5, female n=14]. The body composition and RMR of all the participants were measured after overnight fasting (≥8 h). The Korean version of the WHO Global Physical Activity Questionnaire (GPAQ) was used to assess physical activity. [Results] Body composition was not significantly different between young adults and middle-aged adults. Whole-body bone mineral density and bone mineral contents (BMC) were significantly lower in middle-aged adults than in young adults. Total blood cholesterol (TC) and blood glucose levels were significantly higher in middle-aged adults (TC; 195.21 ± 43.34, glucose; 103.57 ± 12.61 mg/dL) than in young adults. RMR was significantly lower in middle-aged adults (1619.57 ± 290.28 kcal/day) than in young adults (1894.37 ± 405.00 kcal/day). In middle-aged adults physical activity (PA). PA (METs, min, EE) was inversely correlated with fat mass (FM, kg, and %) and blood triglyceride (TG) level in young adults. In middle-aged adults, PA showed a significant positive correlation with lean body mass (LBM), FM (%), and RMR. Furthermore, PA EE showed significant interrelatedness with BMC among middle-aged adults. [Conclusion] These results demonstrated that high PA levels enable LBM and RMR maintenance in middle-aged adults. Furthermore, in young adults, more PA is required to induce change in body composition.

• Proceedings of the KSCN Conference
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• 1998.11a
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• pp.95-95
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• 1998

• Korean Journal of Health Education and Promotion
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• v.7 no.2
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• pp.89-102
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• 1990

The research is a comparative study of death attitudes between male and female elderly people. There is no doubt as to the inevitability of death. And yet, there is a vast conspiracy involved in the word of dead or death. The aged are considered to be nearer death than are people in other age groups. Kalish(1976) emphasized that for the aged two meanings of death have significance for evaluating their life ; first, that older people are known to have a limited life time and face death ; second that older people are known to have suffered many death-imposed losses that are often associated with the dying process. In considering these implications, the level of anxiety regarding death and dying is a crucial factor in determining mental health. In the study, 152 male elderly and 145 female elderly residing in Seoul, Korea was compared on the four dimensions of death anxiety and assigned personal variables. Therefore, the purpose the research was (1) to examine the characteristics of subjects on the independent variables(age, marital status, family relationship, social activities, religiousity etc.) ; (2) to examine the relationship between the independent variables and each dimension of death axniety ; (3) to determine the proportion of variance in the respective of death anxiety which is accounted for by the respective independent variables ; (4) to examine whether a significant difference between the respective independent variables and each dimension of death anxiety has ; (5) to determine the combination of variables which is the most successful in explaining the variance in death anxiety. Finding from this study support the following conclusions; 1. There was a significant differences between the male and female subjects in the level of death anxiety. In turn, the male older adults had lower death anxiety than did the female elderly. This implies that male tend to look forward to death rather than deny it. 2. As there was evidences from several studies, this research found that fear of death decreases as age increases. 3. The following two variables that correlate best with dying anxiety of others in both male and female older adults : 'marriage life', 'social interaction'. 4. The variables 'age' and 'children' for both female and male elderly accounted for the most variance in death anxiety of self. The findings of the study lend this investigator several suggestions, implications and recommendations for future research. There can be no death without life, and conversely, no life without death. Psychologists and health-related professionals may be learn as much about death as they can in order to develop more healthy attitudes and in order to be able to better aid and comfort dying people and their familities. Perhaps most importantly, professionals may be help those who are not faced with death at present to develop an understanding of it and healthy attitudes toward it. The programs of death education are needed for dedication to the evitability of death and the preparation of life for the older adults. More seminars, symposiums and research on death attitudes are needed. Finally, study for female older adults has been negelected topic in the areas of women's study and health education. Future study, for female elderly, have to deeply investigate where those problems come from and how to cope with in order to the female elderly segment can live the rest of their lives in satisfaction with well-being.

• The Journal of Korean Academy of Prosthodontics
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• v.11 no.1
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• pp.9-14
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• 1971

The author measured the maximum interincisal distance by means of the sliding caliper. The subjects measured here were 149 healthy Korean males and 229 females, ranging from 15 to 49 years old, with normal occlusion. The results were as follows; 1. The mean value of maximum interincisal distance was $50.03{\pm}0.22mm$. in male and $45.18{\pm}0.14mm$. in female. 2. There was a significant difference in the mean value between male female. 3. The interincisal distances in maximum opening were slightly larger in male than female. 4. There was no significant difference in the mean value between the age groups in Korean adults. But it has been revealed that there was apparent difference in the mean value between 15~19 years and 20~29 years old, in female. 5. It has been appeared that maximum interincisal distance in male was 69mm, minimum 37mm., and maximum interincisal distance in female was 58mm. minimum. 30mm.