Journal of Preventive Medicine and Public Health
- Volume 21 Issue 1 Serial No. 23
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- Pages.89-98
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- 1988
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- 1975-8375(pISSN)
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- 2233-4521(eISSN)
Seroepidemiology of Hepatitis B Virus Infection in Healthy Korean Adults in Seoul
정상 성인에 있어서의 B형 간염 바이러스 감염에 관한 혈청역학적 연구
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Yoo, Keun-Young
(Department of Preventive Medicine, College of Medicine, Seoul National University) ;
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Park, Byung-Joo
(Department of Preventive Medicine, College of Medicine, Seoul National University) ;
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Ahn, Yoon-Ok
(Department of Preventive Medicine, College of Medicine, Seoul National University)
- Published : 1988.05.01
Abstract
While there have been not a few reports on the seroepidemiological characteristics of hepatitis B virus (HBV) infection in Korea, most of them, however, have had several limitations; operational definition of HBV infection, validity of detection methods of HBV serologic markers, size of the study population, and confirmation of the vaccination history against HBV, etc. In order to avoid such limitations, authors randomly selected 1,495 healthy adults among the 217,511 insured (target population) of Korean Medical Insurance Corporation, living in seoul, and tested HBV serologic markers by RIA method and conducted direct interview to them. Although HBV serologic markers (HBsAg, anti-HBs and anti-HBc) of all the subjects were tested, 392(26.2%) of interview failure cases and 361 vaccinee were excluded from the actual population. Finally, the serologic markers tested of 742 nonvaccinee (study population) only were analysed for the seroepidemiologic observation of the natural infection of HBV. The seroepidemiological characteristics of HBV infection in Korea were as follows ; 1. Point prevalence of HBs antigenemia was 11.7(9.1{\sim}14.3)% in male, which was slightly higher than that of female, 9.5(
Keywords
- Hepatitis B virus;
- Seroepidemiology;
- HBsAg;
- Anti-HBc;
- Anti-HBs;
- Radioimmunoassay;
- Natural infection;
- Carrier state.