• Title/Summary/Keyword: healthy condition

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Three key factors for successful esthetic anterior implant restoration (성공적인 전치부 심미 임플란트를 위한 3가지 요소)

  • Lim, Pil
    • Journal of the Korean Academy of Esthetic Dentistry
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    • v.25 no.1
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    • pp.35-49
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    • 2016
  • With the increasing demand for aesthetic implant dentistry, the importance of implant restoration is emphasized not only in the functional aspect but also in the aesthetic aspect. The aesthetic restoration of dental implants in the anterior maxilla is a challenge for clinicians because it requires proper harmony in three following conditions; reconstruction of hard tissue, soft tissue, and aesthetic prosthesis. The soft tissue aesthetics are dependent upon the condition of the supporting hard tissue because the osseous structure provides a framework for the development of a healthy and aesthetic soft tissue interface. Therefore, the augmentation of hard tissue is a first step and especially, optimal 3-dimensional position of implant is the most important factor in aesthetic implant restoration. The management of soft tissue is a second step, and the final step is a restoration of harmonic prosthesis using provisional restoration with proper emergence profile. This clinical report describes the procedure of bone augmentation in labial dehiscence defect, Vascularized Interpositional Periosteal-Connective Tissue (VIP-CT) flap for aesthetic anterior soft tissue, and the importance of provisional restoration and impression taking stage with customized impression coping.

A Case of Cryptococcosis involving Lung and CNS without Underlying Disease (폐와 중추신경계를 침범한 효모균증(Cryptococcosis) 1예)

  • Lee, Min-Su;Park, Sang-Seon;Koh, Young-Il;Jang, An-Soo;Lim, Sung-Chul;Yang, Ju-Yeoul;Park, Hyung-Kwan;Na, Hyun-Joo;Kim, Young-Chul;Choi, In-Seon;Park, Kyung-Ok
    • Tuberculosis and Respiratory Diseases
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    • v.42 no.4
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    • pp.618-623
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    • 1995
  • Cryptococcosis is a systemic mycosis that most often involves the lungs and central nervous system and, less frequently, the skin, skeletal system, and prostate gland. Cryptococcus neoformans, the causative organism, is a yeastlike round or oval fungus, 4 to $6{\mu}m$ in diameter, which is surrounded by a polysaccharide capsule and reproduces by budding and found in soil and other environmental areas, especially those contaminated by pigeon droppings. Humans and animals acquire infection after inhalation of aerosolized spores. Condition or factors that predispose to cryptococcosis include corticosteroid therapy, lymphoreticular malignancies, HIV infection, and sarcoidosis etc. We discribed a case of cryptococcosis involving lung and CNS coincidently without specific underlying disease and the literature on subject were reviewed. A fifty-six year-old previously healthy female presented with headache of 3 months of duration. She had no history suggesting immunologic suppression and we could not find any abnormal laboratory findings including blood sugar, serum immunoglobulin and complement level, HIV antibody, and T cell subsets. Chest roentgenogram and CT scan showed a solitary soft tissue mass in LUL with distal pneumonitis. Brain MRI showed granulomatous lesion in cerebellum and parasagittal cortex of right frontal lobe. The diagnosis was made by bronchoscopic brushing cytology, transthoracic fine needle aspiration, and sputum KOH mount and culture. She was treated 6 weeks course of Amphotericin B and switched to oral fluconazole therapy for 3 months. Her symptoms and X-ray findings were improved gradually and she is now under regular clinical follow up.

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Effects of Melatonin on the Meiotic Maturation of Mouse Oocytes in vitro (생쥐 난자의 체외 성숙에 미치는 Melatonin의 영향)

  • Ahn, Hee-Jin;Bae, In-Ha
    • Clinical and Experimental Reproductive Medicine
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    • v.31 no.3
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    • pp.155-168
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    • 2004
  • Objective: Melatonin, which is secreted by pineal gland play an important role in the regulation of ovarian function via seasonal rhythm and sleep in most mammals. It also has a role in the protection of cells by removing toxic oxygen free radicals brought about by metabolism. In the present study, effects of melatonin on the mouse oocyte maturation were examined using two different culture conditions provided with 5% or 21% oxygen concentration. Material and Method: Immature mouse oocytes were obtained from the ovarian follicles of $3{\sim}4$ weeks old ICR strain mice intraperitoneally injected with 5 I.U. PMSG 44 hour before. Under stereomicroscope, morphologically healthy oocytes with distinct germinal vesicle (GV) were liberated from the graafian follicles and collected using mouth-controlled micropipette. They were then cultured for 17 hour at $37^{circ}C$, 5% $CO_2$ and 21% $O_2$ (95% air) or 5% $CO_2$, 5% $O_2$ and 90% $N_2$. New modified Hank's balanced salt solution (New MHBS) was used as a culture medium throughout the experiments. Effects of melatonin were examined at a concentration of $0.0001{\mu}M$, $0.01{\mu}M$ or $1.0{\mu}M$. For the prevention of spontaneous maturation of immature oocytes during culture, dibutyryl cyclic AMP (dbcAMP) and/or hypoxanthine were included in the medium. Results: Under 21% oxygen condition, oocytes cultured in the presence of $0.01{\mu}M$ melatonin showed a significantly higher maturation rates, in terms of germinal vesicle breakdown (95.0% vs 89.0%) and polar body formation (88.1% vs 75.4%), compared to those cultured with $0.0001{\mu}M$ or $1.0{\mu}M$ melatonin. However, no difference was observed in oocytes cultured under 5% oxygen whether they were treated with melatonin or not. In the presence of $0.01{\mu}M$ melatonin, oocytes either cultured under 21% or 5% oxygen exhibited no difference in the polar body formation (85.6% vs 86.7%). However, in the absence of melatonin, oocytes cultured under 21% oxygen exhibited lower polar body formation (74.7%). When oocytes were cultured in the presence of dbcAMP alone or with varying concentrations of melatonin, those treated with both compounds always showed better maturation, i.e., germinal vesicle breakdown and polar body formation, compared to those cultured with dbcAMP alone. At the same concentration of melatonin, however, oocytes exposed to 21% oxygen showed poor maturation than those to 5% oxygen. Similar results were obtained from the experiments using hypoxanthine instead of dbcAMP. Conclusion: Based upon these results, it is suggested that melatonin could enhance the meiotic maturation of mouse oocytes under 21% oxygen concentration, and release oocytes from the meiotic arrest by dbcAMP or hypoxanthine regardless of the concentration of oxygen, probably via the removal of oxygen free radicals.

Standardization of Hydration in the Stratum Corneum Using by Polyols (폴리올을 이용한 각질층 수분량 측정의 표준화 연구)

  • Nam, Gaewon
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.41 no.2
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    • pp.113-119
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    • 2015
  • The measurement of hydration level in the surface layer of the skin, stratum corneum (SC), gives important information on the biophysical properties and function of the skin barrier such as softness, flexibility, and healthiness of the skin. But it is difficult to measure a consistent hydration level from a sample to another sample due to individual variations and environmental changes. The aim of this study was to evaluate objective hydration after using various products in the SC. The SC Hydration was measured by capacitance (Corneometer$^{(R)}$, C+K, Germany) on the ventral site of forearm from 40 healthy volunteers. The skin surface was chronologically measured immediately after application of the test products and 3 and 6 hours later. We analyzed the averages of five measurements of each site and used the hydration increase rate for correction on untreated site variation. We found that most polyols including glycerol and butylenes glycol influenced directly the hydration increase rate in the SC previously. In this study, glycerol was used to prepare the standard products from 0 to 20 percents and applied to the same volunteers. The individual standard curve showed linear relation to glycerol concentrations. Based on the the standard curve, hydration of SC was converted into hydration increase rate to glycerol concentrations. The converted glycerol concentrations of products were repetitive and reproducible. In addition, the individual standard curve was used to relate the skin type of each individual. These results suggest that the hydration of the SC standardized regardless of external variation and individual skin condition can explain detailed skin state variation. Further studies will be conducted with other ingredients such as surfactants, lipids and aqueous materials, and with other methods for noninvasive measurement.

Inter-Rater Reliability of Abdominal Muscles Thickness Using Ultrasonography for Different Probe Locations and Thickness Measurement Techniques

  • Lim, One-Bin;Hong, Ji-A;Yi, Chung-Hwi;Cynn, Heon-Seock;Jung, Doh-Heon;Park, Il-Woo
    • Physical Therapy Korea
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    • v.18 no.4
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    • pp.60-67
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    • 2011
  • Ultrasonography (US) is a recent technique that has proven to be useful for assessing muscle thickness and guiding the rehabilitation decision-making of clinicians and researchers. The purpose of this study was to determine the inter-rater reliability of the US measurement of transversus abdominis (TrA), internal oblique (IO), and external oblique (EO) thicknesses for different probe locations and measurement techniques. Twenty healthy volunteers were recruited in this study. Muscle thicknesses of the transversus TrA, IO, and EO were measured three times in the hook-lying position. The three different probe locations were as follows: 1) Probe location 1 (PL1) was below the rib cage in direct vertical alignment with the anterior superior iliac spine (ASIS). 2) Probe location 2 (PL2) was halfway between the ASIS and the ribcage along the mid-axillary line. 3) Probe location 3 (PL3) was halfway between the iliac crest and the inferior angle of the rib cage, with adjustment to ensure the medial edge of the TrA. The two different techniques of thickness measurement from the captured images were as follows: 1) Muscle thickness was measured in the middle of the muscle belly, which was centered within the captured image (technique A; TA). 2) Muscle thickness was measured along a horizontal reference line located 2 cm apart from the medial edge of the TrA in the captured image (technique B; TB). The intraclass correlation coefficient (ICC [3,k]) was used to calculate the inter-rater reliability of the thickness measurement of TrA, IO and EO using the values from both the first and second examiner. In all three muscles, moderate to excellent reliability was found for all conditions (probe locations and measurement techniques) (ICC=.70~.97). In the PL1-TA condition, inter-rater reliability in the three muscle thicknesses was good to excellent (ICC=.85~.96). The reliability of all measurement conditions was excellent in IO (ICC=.95~.97). Therefore, the findings of this study suggest that TA can be applied to PL1 by clinicians and researchers in order to measure the thickness of abdominal muscles.

Ecological Health Assessments on Stream Order in Southern Han River Watershed and Physical Habitat Assessments (남한강 수계에서 하천차수에 따른 생태건강도 평가 및 지점별 물리적 서식지 평가)

  • Choi, Ji-Woong;An, Kwang-Guk
    • Korean Journal of Environmental Biology
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    • v.31 no.4
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    • pp.440-447
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    • 2013
  • The ecological health, based on the Index of Biological Integrity (IBI) and Qualitative Habitat Evaluation Index (QHEI) was evaluated in 10 stream sites of Southern Han River. Eleven parameters of 12 parameters (Karr 1981) were modified for the application of regional Korean circumstance. The ecological health, based on IBI grade, was in "good condition" and the IBI score ranged from 33 to 47. Nine parameters of the original 12-parameter metrics in QHEI model (Plafkin et al. 1989) were applied in the habitat assessment. The mean QHEI model values were judged as "partially supporting" and ranged from 75 (non-supporting) to 109 (supporting). Comparative analyses revealed that values of IBI and QHEI models were greater in Gj stream than Ig- and Dn streams. The analysis of fish compositions showed that the proportions of insectivore, omnivore, and carnivore were 61.9%, 19%, and 9.5%, respectively. According to tolerance guild analysis, sensitive species and tolerant species were 76.1% and 4.7%, respectively, indicating a healthy trophic state in terms of food chain. The analysis by habitat guild type indicated that riffle benthic species dominated (57.1%) when compared to water column species (28.5%). The introduced species and individuals with diseases or external abnormality were not observed. Overall, the model values of IBI and QHEI suggested that the ecological health was maintained well in this upstream region.

Determination of Risk Indicators for Establishing the Health Evaluation System of Old Trees (노거수의 건강성 평가체계 정립을 위한 위험 지표인자의 검증)

  • Zhang, Zhong-Feng;Xia, Tian-Tian;Kang, Ho-Chul;Kang, Tai-Ho
    • Journal of the Korean Institute of Landscape Architecture
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    • v.46 no.4
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    • pp.49-60
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    • 2018
  • The protection and management of old trees is important in the context of heritage protection and landscape construction. The purpose of this study is to determine the risk indicators of the health evaluation system for the old trees, and to provide methods for the protection and management of the old trees that are at risk. According to the index and weighted values obtained in the previous study the scores can be calculated on a 100-point scale. According to the score, the grades are divided into 5 levels. This study takes the case of a total of 30 old trees, including a Chinese juniper, located in Gyeongju Yangdong village, to evaluate the degree of danger in their actual condition. The results showed that of the Chinese juniper tree is at the healthy level, with the score of about 70, and is therefore in Level C. The trees in Yangdong village at high risk should be improved quickly. The standards set for the 5-level score graph and the establishment of a health evaluation system can reflect the actual situation of the old trees in Yangdong village, so it is both practical and scientific.

Photocatalytic disinfection of indoor suspended microorganisms (Escherichia coli and Bacillus subtilis spore) with ultraviolet light (광촉매와 UVA에 의한 실내 부유 미생물(E. coli 및 Bacillus. subtilis sp.) 살균 제거 연구)

  • Yoon, Young H.;Nam, Sook-Hyun;Joo, Jin-Chul;Ahn, Ho-Sang
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.2
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    • pp.1204-1210
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    • 2014
  • New control methods are proposed for indoor air quality by removing fine airborne dust-particles. As suspended fine dust-particles contain inorganic dust as well as fine organic bacteria, studies for simultaneous control of these contaminants are required. In this study, photocatalytic disinfection of indoor suspended microorganisms such as E. coli and Bacillus subtilis is performed by three types of photocatalysts with UVA irradiation. The UVA irradiation strength was controlled to the minimum $3{\mu}W/cm^2$, and ZnO, $TiO_2$, and ZnO/Laponite ball were used as the catalysts. The results indicate that E. coli was removed over 80 % after about 2 hours of reaction with UVA and all three types of photocatalysts, whereas only with UVA, around 50 % E. coli removal was obtained. Among the catalysts, ZnO/Laponite composite ball was found to have similar sterilizing capacity to $TiO_2$. However, in case of B. subtilis, which has thick cell wall in its spore state, disinfection was not effective under the low UVA irradiation condition, even with the catalysts. Further studies need to figure out the optimal UVA irradiation ranges as well as photocatalysts doses to control airborne dust, to provide healthy clean air environment.

Mechanical Properties of Unilateral & Bilateral Movement in Isokinetic Knee Extension and Flexion (등속성 무릎 굴곡과 신전 시 외측 및 양측운동의 역학적 특성)

  • Kim, Yong-Woon;Kim, Yong-Jae
    • Korean Journal of Applied Biomechanics
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    • v.18 no.3
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    • pp.83-92
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    • 2008
  • Y. W. KIM, Y. J. KIM, Mechanical Properties of Unilateral & Bilateral Movements in Isokinetic Knee Extension and Flexion. Korean Journal of Sport Biomechanics, Vol. 18, No. 3, pp. 83-92, 2008. The purpose of this study was to examine the mechanical properties and patterns of bilateral and unilateral movement under varying velocities and movement patterns. The unilateral and bilateral isokinetic knee extension and flexion were taken for three speeds of 13 healthy male subjects. Although there was bilateral facilitation at the speed of $450^{\circ}$/s for the bilateral movement of knee extension, as a whole there was less resultant torque and power of bilateral movement than summed unilateral under knee flexion and extension of 3 velocity condition. There was significant correlations between bilateral deficits within individuals observed for an the same movement($120^{\circ}-240^{\circ}$ flexion, $120-240^{\circ}$ extension, $240^{\circ}-450^{\circ}$ extension), which means that same agonist was recruited. On the contrary, although there was a tendency of a similar pattern of the individuals bilateral deficit according to the varying velocities, there was not a significant correlations between bilateral deficits of flexion and extension within individual, which means that different agonist was recruited. With the analyses of this results the individuals neuromuscular characteristics and the effecting factors for bilateral movement can be speculated upon.

Comparison of $LigaSure^{TM}$ and Bipolar Vessel Sealing System for Laparoscopic Ovariectomy in Cats (복강경을 이용한 고양이의 난소 절제술에서 지혈기구인 $LigaSure^{TM}$와 양극 전기 응고 장치(bipolar)의 비교)

  • Jin, So-Young;Lee, Seung-Yong;Park, Se-Jin;Kim, Young-Ki;Seok, Seong-Hoon;Hwang, Jae-Min;Yeon, Seong-Chan
    • Journal of Veterinary Clinics
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    • v.31 no.6
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    • pp.477-482
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    • 2014
  • The aim of this study was to investigate and compare technique, surgical time, and complications of laparoscopic ovariectomy using $LigaSure^{TM}$ and bipolar vessel sealing system in cats. Laparoscopic ovariectomy was performed under general anesthesia on 10 healthy female cats admitted for elective ovariectomy. Surgery was performed through three midline portals. Each ovary was randomly-assigned to removal by use of either $LigaSure^{TM}$ or bipolar vessel sealing system. Duration of predetermined surgery intervals and complications were compared. Bipolar OVE ($2:16{\pm}1:14$ minutes) took significantly longer surgical time compared to the $LigaSure^{TM}$ OVE ($1:24{\pm}0:59$ minutes, P = 0.021). The ovarian pedicle fat and obesity did not influence surgery duration. Intraoperative hemorrhage occurred with bipolar OVE in three cats, but had no significant influence on surgical time. The results suggest that both $LigaSure^{TM}$ and bipolar devices appear to be effective, but $LigaSure^{TM}$ can be used as a stand-alone device that decreases surgical time and complication compared with bipolar vessel sealing system.