• Title/Summary/Keyword: health indicators

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Study on the Anti-stress Effect of Chenwangbosim-Dan Extract∘Fermented Rice Extract (GABA ː gamma-aminobutyric acid 30%) Complex : A double-blind, randomized, placebo-controlled study (천왕보심단(天王補心丹)∘쌀발효추출물(GABAːgamma-aminobutyric acid 30%) 복합물의 항(抗)스트레스에 대한 유효성 연구ː무작위 배정 및 이중맹검)

  • Choyoung, Hong;Seo, Sang Gwon;Seunggon, Na;Hosong, Cho;Mi-Kyung, Lee;Mu Hyun, Jin;Seok-Seon, Roh;Youngsung, Ju
    • The Korea Journal of Herbology
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    • v.38 no.2
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    • pp.1-7
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    • 2023
  • Objectives : From this study, we sight to identify Anti-stress effect of Chenwangbosim-Dan (Tianwangbuxin-Dan) Extract∘Fermented Rice Extract (GABA : gamma-aminobutyric acid 30%) Complex Methods : In order to measure the degree of functional evaluation of tension relief due to stress, it was evaluated whether the psychological indicators VAS(Visual Analog Scale) and POMS(Profile Of Mood State) were improved. Which is generally used for stress measurement and has a high frequency of clinical use. All clinical trial subjects were required to take the drug once a day at 9 ± 30 min in the morning for 2 weeks. Results : After intake, the group that Chenwangbosim-Dan(Tianwangbuxin-Dan) Extract∘Fermented Rice Extract (GABA : gamma-aminobutyric acid 30%) Complex had a statistically significant improvement effect compared to before intake due to an improved 30.81% of the VAS scores. The POMS-T score improved 54.13%, the POMS-V score improved 117.5% and the POMS-F score improved 59%, which had a statistically significant effect compared to Placebo group (p<0.001). There is a significant difference between two group, so even considering the placebo effect, the anti stress effect was confirmed in the Chenwangbosim-Dan (Tianwangbuxin-Dan) Extract∘Fermented Rice Extract (GABA : gamma-aminobutyric acid 30%) Complex intake group. Conclusions : The above results showed that the Chenwangbosim-Dan(Tianwangbuxin-Dan) Extract∘Fermented Rice Extract (GABA : gamma-aminobutyric acid 30%) Complex had an anti-stress effect. Therefore, it is expected to be developed as a safe and comfortable mental care health functional food that can reduce the risk of drug abuse.

Blood Biomarkers for Alzheimer's Dementia Diagnosis (알츠하이머성 치매에서 혈액 진단을 위한 바이오마커)

  • Chang-Eun, Park
    • Korean Journal of Clinical Laboratory Science
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    • v.54 no.4
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    • pp.249-255
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    • 2022
  • Alzheimer's disease (AD) represents a major public health concern and has been identified as a research priority. Clinical research evidence supports that the core cerebrospinal fluid (CSF) biomarkers for AD, including amyloid-β (Aβ42), total tau (T-tau), and phosphorylated tau (P-tau), reflect key elements of AD pathophysiology. Nevertheless, advances in the clinical identification of new indicators will be critical not only for the discovery of sensitive, specific, and reliable biomarkers of preclinical AD pathology, but also for the development of tests that facilitate the early detection and differential diagnosis of dementia and disease progression monitoring. The early detection of AD in its presymptomatic stages would represent a great opportunity for earlier therapeutic intervention. The chance of successful treatment would be increased since interventions would be performed before extensive synaptic damage and neuronal loss would have occurred. In this study, the importance of developing an early diagnostic method using cognitive decline biomarkers that can discriminate between normal, mild cognitive impairment (MCI), and AD preclinical stages has been emphasized.

Study on User Characteristics based on Conversation Analysis between Social Robots and Older Adults: With a focus on phenomenological research and cluster analysis (소셜 로봇과 노년층 사용자 간 대화 분석 기반의 사용자 특성 연구: 현상학적 분석 방법론과 군집 분석을 중심으로)

  • Na-Rae Choi;Do-Hyung Park
    • Journal of Intelligence and Information Systems
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    • v.29 no.3
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    • pp.211-227
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    • 2023
  • Personal service robots, a type of social robot that has emerged with the aging population and technological advancements, are undergoing a transformation centered around technologies that can extend independent living for older adults in their homes. For older adults to accept and use social robot innovations in their daily lives on a long-term basis, it is crucial to have a deeper understanding of user perspectives, contexts, and emotions. This research aims to comprehensively understand older adults by utilizing a mixed-method approach that integrates quantitative and qualitative data. Specifically, we employ the Van Kaam phenomenological methodology to group conversations into nine categories based on emotional cues and conversation participants as key variables, using voice conversation records between older adults and social robots. We then personalize the conversations based on frequency and weight, allowing for user segmentation. Additionally, we conduct profiling analysis using demographic data and health indicators obtained from pre-survey questionnaires. Furthermore, based on the analysis of conversations, we perform K-means cluster analysis to classify older adults into three groups and examine their respective characteristics. The proposed model in this study is expected to contribute to the growth of businesses related to understanding users and deriving insights by providing a methodology for segmenting older adult s, which is essential for the future provision of social robots with caregiving functions in everyday life.

The Effect of Pilates Mat Exercise on Cardiovascular Disease Risk Factors and Inflammation Markers in Sarcopenic Obesity Elderly (필라테스 매트운동이 근위축 비만 노인의 심혈관질환 위험요인과 염증반응지표에 미치는 영향)

  • Kim, Hyun-Tae;Kim, Nam-Jung
    • 한국체육학회지인문사회과학편
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    • v.51 no.4
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    • pp.407-417
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    • 2012
  • The purpose of the study was to determine the effects of pilates mat exercise on cardiovascular disease risk factors and inflammation markers in sarcopenic obesity elderly. All subjects were sarcopenic obesity(height for each of the arms, legs, appendicular muscle mass ratio of 1.16kg/m2, 4.31kg/m2, 5.21kg/m2 under and % body fat is more than 30%) elderly performed the pilates mat exercise during 12-week for 60 minutes 3 times a weeks. All subjects of this study were examined the changes in cardiovascular disease risk factors(TC, TG, HDL-C, LDL-C, Glucose, Insulin) and inflammation markers(fibrinogen, adiponectin, leptin, CRP). The results of the study in the exercise group were as follows; The weight, % body fat, TC, TG, LDL-C, fibrinogen, CRP had significantly decreased and muscle mass, HDL-C, adiponectin had significantly increased. And also, pilates mat exercise can effective to improve sarcopenic obesity, and pilates mat exercises performed coy shrink obesity to cardiovascular disease and inflammatory response indicators of older women as old man's physical features of the deterioration of the prevention of obesity and muscle strength loss, causing the effective exercise method is meant to be.

Leading, Coincident, Lagging INdicators to Analyze the Predictability of the Composite Regional Index Based on TCS Data (지역 경기종합지수 예측 가능성 검토를 위한 TCS 데이터 선행·동행·후행성 분석 연구)

  • Kang, Youjeong;Hong, Jungyeol;Na, Jieun;Kim, Dongho;Cheon, Seunghun
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.21 no.1
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    • pp.209-220
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    • 2022
  • With the worldwide spread of African swine fever, interest in livestock epidemics has increased. Livestock transport vehicles are the main cause of the spread of livestock epidemics, but there are no empirical quarantine procedures and standards related to the mobility of livestock transport vehicles in South Korea. This study extracted the trajectory of livestock-related vehicles using the facility-visit history data from the Korea Animal Health Integrated System and the DTG (Digital Tachograph) data from the Korea Transportation Safety Authority. The results are presented as exposure indices aggregating the link-time occupancy of each vehicle. As a result, 274,519 livestock-related vehicle trajectories were extracted, and the exposure values by link and zone were derived quantitatively. This study highlights the need for prior monitoring of livestock transport vehicles and the establishment of post-disaster prevention policies.

Investigating the Influence of ESG Information on Funding Success in Online Crowdfunding Platform by Using Text Mining Technique and Logistic Regression

  • Kyu Sung Kim;Min Gyeong Kim;Francis Joseph Costello;Kun Chang Lee
    • Journal of the Korea Society of Computer and Information
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    • v.28 no.7
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    • pp.155-164
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    • 2023
  • In this paper, we examine the influence of Environmental, Social, and Governance (ESG)-related content on the success of online crowdfunding proposals. Along with the increasing significance of ESG standards in business, investment proposals incorporating ESG concepts are now commonplace. Due to the ESG trend, conventional wisdom holds that the majority of proposals with ESG concepts will have a higher rate of success. We investigate by analyzing over 9000 online business presentations found in a Kickstarter dataset to determine which characteristics of these proposals led to increased investment. We first utilized lexicon-based measurement and Feature Engineering to determine the relationship between environment and society scores and financial indicators. Next, Logistic Regression is utilized to determine the effect of including environmental and social terms in a project's description on its ability to obtain funding. Contrary to popular belief, our research found that microentrepreneurs were less likely to succeed with proposals that focused on ESG issues. Our research will generate new opportunities for research in the disciplines of information science and crowdfunding by shedding new light on the environment of online micro-entrepreneurship.

The effectiveness and safety of acupuncture combination treatment on smoking cessation: A protocol for systematic review (금연에 대한 침술 병용 치료의 효과 및 안전성 : 체계적 검토를 위한 프로토콜)

  • In Suh Choi;Won-Suk Sung;Min-gi Jo;Jung-Hyun Kim;Yeon-Cheol Park;Eun-Jung Kim;Yong-Hyeon Baek;Geun-Woo Kim;Byung-Kwan Seo
    • Journal of Convergence Korean Medicine
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    • v.3 no.1
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    • pp.5-13
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    • 2022
  • Objectives: Smoking had a long negative impact on public health. The ingredients of a cigarette are major risk factors for several diseases. Owing to the problems about economic and quality of life, we need to ensure smoking cessation (SC). There are several approaches for SC including pharmacological therapy, nicotine replacement therapy, education, and behavioral intervention. However, due to some limitations, other alternative approaches are gaining popularity. Acupuncture has been reported to have few side effects and be more effective than some conventional treatments in several articles. However, there are no systematic reviews on the comparison of acupuncture combination treatment with other conventional monotherapies. Methods: Randomized controlled trials that used acupuncture as an adjunct treatment for SC will be searched and data will be summarized according to the predefined criteria. The primary outcome will be the abstinence rate, and secondary outcomes will be adverse events and biochemical indicators. We will use Review Manager to perform a meta-analysis, Cochrane Collaboration Risk of Bias tool for the risk of bias assessment, and the Grades of Recommendation, Assessment, Development and Evaluation approach to determine the quality of evidence. We will investigate the efficacy and safety of acupuncture combination treatment for SC with this study. Ethics and dissemination: This study will provide reliable clinical evidence on additional effect of acupuncture on smoking cessation. We will publish our results in a peer-review journal.

Journal of Knowledge Information Technology and Systems (스마트축사 활용 가상센서 기술 설계 및 구현)

  • Hyun Jun Kim;Park Man Bok;Meong Hun Lee
    • Smart Media Journal
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    • v.12 no.10
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    • pp.55-62
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    • 2023
  • Innovation and change are occurring rapidly in the agriculture and livestock industry, and new technologies such as smart bams are being introduced, and data that can be used to control equipment is being collected by utilizing various sensors. However, there are various challenges in the operation of bams, and virtual sensor technology is needed to solve these challenges. In this paper, we define various data items and sensor data types used in livestock farms, study cases that utilize virtual sensors in other fields, and implement and design a virtual sensor system for the final smart livestock farm. MBE and EVRMSE were used to evaluate the finalized system and analyze performance indicators. As a result of collecting and managing data using virtual sensors, there was no obvious difference in data values from physical sensors, showing satisfactory results. By utilizing the virtual sensor system in smart livestock farms, innovation and efficiency improvement can be expected in various areas such as livestock operation and livestock health status monitoring. This paper proposes an innovative method of data collection and management by utilizing virtual sensor technology in the field of smart livestock, and has obtained important results in verifying its performance. As a future research task, we would like to explore the connection of digital livestock using virtual sensors.

A study on TOC monitoring and spatial distribution analysis using a spectrometer in rivers (하천에서의 분광측정기를 이용한 TOC 모니터링 및 공간분포 분석 연구)

  • Yoon, Soo Bin;Lee, Chang Hyun;Kim, Young Do
    • Journal of Korea Water Resources Association
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    • v.56 no.11
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    • pp.815-822
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    • 2023
  • Organic pollution is one of the most common forms of water contamination. Under the Water Quality Conservation Act, indicators for measuring organic substances include BOD, COD, and TOC. Analysis of BOD and COD is labor-intensive, and in the case of organic substances where biological decomposition is not feasible or toxic substances are present, the accuracy is often low. Therefore, the Ministry of Environment is shifting towards TOC-centric management. With advancements in sensor technology today, various parameters can be monitored using sensors. In this study, digital monitoring of river TOC using a spectrophotometer called Spectro::lyser V3 was conducted. Initially, experiments were carried out at the Andong River Experiment Center to assess the applicability of the measurement equipment. Subsequently, data collected at the confluence of the Nakdong River was analyzed for the spatial distribution of TOC using the Kriging technique. This research proposes the utilization of sensors for river TOC monitoring and spatial distribution analysis. Real-time monitoring of changes in river TOC concentration can serve as fundamental data for pollution monitoring and response. Sensor-based river monitoring offers advantages in terms of temporal resolution and real-time data acquisition. When various spatial information interpretation methods are applied, it is expected to contribute to diverse studies such as aquatic ecological health, river water source selection, and stratification analysis in the future.