• Title/Summary/Keyword: harmful substance

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A Study on Zone-based Risk Analysis System using Real-time Data (실시간 데이터를 이용한 지역기반 위험분석 시스템에 관한 연구)

  • Oh, Jeong Seok;Bang, Hyo Jung
    • Journal of the Korean Institute of Gas
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    • v.17 no.6
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    • pp.83-89
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    • 2013
  • Energy industry facilities can cause fatal damage for internal industry employee as well as external general people because handling various kinds of gas and harmful substance might be spread to large scale severe accident by fire, explosion, and toxic gas leakage. In order to prevent these accidents, quantification by damage effect on structure and human is tried by using quantitative risk assessment, but it is difficult to process instantly exceptional cases and requires knowledge of expert. This paper aims to minimize exceptional cases and knowledge of expert, and present risk with human perceptible. So, we designed and developed zone-base risk analysis system that can compute risk of zone in real time at that point using database and incremental model.

Supplementation of Laurus nobilis Attenuate Ethanol-induced Psychomotor Alterations in Rats

  • dela Pena, Irene Joy I.;de la Pena, June Bryan;Yoon, Seo Young;Kim, Hee Jin;Lee, Jin Hee;Paek, Se Hee;Seo, Yong Ki;Park, Seok Jun;Moon, Byoung Seok;Cheong, Jae Hoon
    • Natural Product Sciences
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    • v.20 no.1
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    • pp.44-50
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    • 2014
  • Laurus nobilis (L. nobilis) is traditionally used as an herbal medicine to treat various diseases. Ethanol (EtOH) consumption entails physiological, mental and psychomotor alterations. The aim of the present study was to assess the effects of L. nobilis in attenuating the EtOH-induced psychomotor alterations. L. nobilis was administered to SD rats, 30 minutes before EtOH administration (4 g/kg), at doses of 25, 50 and 100 mg/kg. Evaluations of psychomotor activity in the open-field, accelerating rota-rod, wire, and swimming ability were done at 1, 2, 4 and 8 hours after EtOH administration. In addition, blood ethanol and acetaldehyde levels were also measured. Pre-treatment of L. nobilis significantly improved EtOH-induced psychomotor alterations and decreased blood ethanol and acetaldehyde levels. These findings suggest that L. nobilis might be an effective substance to attenuate the harmful effects of EtOH, particularly psychomotor alterations, and can potentially be considered as a functional food.

Quantitative Exposure Assessment of Various Chemical Substances in a Wafer Fabrication Industry Facility

  • Park, Hyun-Hee;Jang, Jae-Kil;Shin, Jung-Ah
    • Safety and Health at Work
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    • v.2 no.1
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    • pp.39-51
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    • 2011
  • Objectives: This study was designed to evaluate exposure levels of various chemicals used in wafer fabrication product lines in the semiconductor industry where work-related leukemia has occurred. Methods: The research focused on 9 representative wafer fabrication bays among a total of 25 bays in a semiconductor product line. We monitored the chemical substances categorized as human carcinogens with respect to leukemia as well as harmful chemicals used in the bays and substances with hematologic and reproductive toxicities to evaluate the overall health effect for semiconductor industry workers. With respect to monitoring, active and passive sampling techniques were introduced. Eight-hour long-term and 15-minute short-term sampling was conducted for the area as well as on personal samples. Results: The results of the measurements for each substance showed that benzene, toluene, xylene, n-butyl acetate, 2-methoxy-ethanol, 2-heptanone, ethylene glycol, sulfuric acid, and phosphoric acid were non-detectable (ND) in all samples. Arsine was either "ND" or it existed only in trace form in the bay air. The maximum exposure concentration of fluorides was approximately 0.17% of the Korea occupational exposure limits, with hydrofluoric acid at about 0.2%, hydrochloric acid 0.06%, nitric acid 0.05%, isopropyl alcohol 0.4%, and phosphine at about 2%. The maximum exposure concentration of propylene glycol monomethyl ether acetate (PGMEA) was 0.0870 ppm, representing only 0.1% or less than the American Industrial Hygiene Association recommended standard (100 ppm). Conclusion: Benzene, a known human carcinogen for leukemia, and arsine, a hematologic toxin, were not detected in wafer fabrication sites in this study. Among reproductive toxic substances, n-butyl acetate was not detected, but fluorides and PGMEA existed in small amounts in the air. This investigation was focused on the air-borne chemical concentrations only in regular working conditions. Unconditional exposures during spills and/or maintenance tasks and by-product chemicals were not included. Supplementary studies might be required.

Quantitative Determination of Cristobalite Content in Diatomite and Filtered Food (규조토와 여과식품 중 크리스토발라이트의 정량분석)

  • Jeong, Gi Young
    • Journal of the Mineralogical Society of Korea
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    • v.32 no.4
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    • pp.313-321
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    • 2019
  • Diatomite is a silicic porous sedimentary rock composed of diatom frustules, used for filtration aid, filler, absorbent, abrasive, carrier, insulator, and fertilizer. During the calcination of diatomite to improve physical properties for filtration-aid application, amorphous silica is transformed to cristobalite. X-ray diffraction and scanning electron microscopy studies were carried out for 17 diatomite samples, showing that 16 diatomite samples contain cristobalite in the range of 6~100 %. Concentration of respirable cristobalite in air is regulated as harmful substances, but the residual cristobalite in food is treated as generally safe substance. The determination procedure of cristobalite content in food was established for managing food safety. Calibration curve of cristobalite filtered on silver membrane were obtained by X-ray diffraction. The lower limit of quantification was evaluated as 2.7 mg. The cristobalite was not detected in the analyses of selected food samples using the established procedure.

A statistical prediction for concentrations of Manganese in the ambient air (통계적 모형을 이용한 대기중 망간 농도 예측)

  • Kwon, Hye Ji;Kim, Yongku
    • Journal of the Korean Data and Information Science Society
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    • v.27 no.3
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    • pp.577-586
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    • 2016
  • Hazardous air pollution caused by heavy metals in the air is at a serious level. Although manganese(Mn), one of the heavy metals, is a non-carcinogenic substance, it has a harmful influence on the human body. It is partially measured because automatic monitoring technologies have not yet be fully established. We introduced a statistical model for the daily concentration of manganese. Incorporating a linkage between Mn and meteorology, the proposed model is formulated in way to identify meteorological effects and to allow for seasonal trends, enabling not only accurate measurement of manganese concentration, but also information about the evaluation on a Hazard Quotient (non-cancer risk).

A study on the new manufacturing processes of high quality salt without hazardous ingredients (유해성분이 없는 고품질 소금의 새로운 제조공정에 관한 연구)

  • Kim, Kyung-Geun;Mun, Soo-Beom;Shao, Yudo
    • Journal of Advanced Marine Engineering and Technology
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    • v.40 no.6
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    • pp.458-467
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    • 2016
  • Salt is the most important substance in physiological activities of the human body concerning transport of the ingested nutrients into the blood. Thus, the most ideal salt must not contain any harmful ingredients such as cadmium, mercury, lead, and arsenic. However, it is legal to include trace amounts of the hazardous ingredients in salt owing to a technical limitation, because salt is generally obtained from seawater. This paper reported an experimental result about a new method of manufacturing high-quality table salts without hazardous ingredients by using "$15^{\circ}C$ low-temperature vacuum drying technology," applied to the sequential extraction phenomenon of seawater with increasing the concentration. The world's best table salt can be produced if the present results are applied and extended to the traditional solar salt industry.

Mitigating Effect of Resveratrol on the Structural Changes of Mice Liver and Kidney Induced by Cadmium; A Stereological Study

  • Rafati, Ali;Hoseini, Leila;Babai, Ali;Noorafshan, Ali;Haghbin, Hossein;Karbalay-Doust, Saied
    • Preventive Nutrition and Food Science
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    • v.20 no.4
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    • pp.266-275
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    • 2015
  • Exposure to cadmium (Cd) has harmful effects on the liver and kidney. Resveratrol (RES) is an herbal substance that functions as a protective mediator. This study aimed to investigate the effects of RES on the histology of liver and kidney in Cd-exposed mice. Male mice were divided into 4 groups daily receiving normal saline (1 mL normal saline/d), Cd (1 mg/kg/d), RES (20 mg/kg/d), and Cd plus RES, respectively. After 4 weeks, the liver and kidney components were evaluated using stereological methods. The total volume and number of hepatocytes, and volume of fibrous tissue were respectively increased by 34%, 58%, and a 3-fold in the Cd-exposed mice in comparison to the control animals (P<0.03). On the other hand, the volume of the main vasculature (sinusoids and central veins) was decreased by 36% in the Cd group compared to the control mice (P<0.03). Considering the kidney, the results showed a 3-fold increase in the total glomeruli volume and a 7-fold increase in fibrous tissue in the Cd-treated group compared to the control mice (P<0.03). After Cd treatment, a 32% reduction was observed in the volume and length of the proximal and distal convoluted tubules. RES-treatment alone did not induce any structural changes. In comparison to the Cd group, an increase in the normal components of the liver and kidney and a decrease in the formation of the fibrous and degenerated tissues were observed in the Cd+RES-treated mice (P<0.03).

Adsorption Characteristics of Malachite Green on Zeolite (제올라이트에 의한 말라카이트 그린의 흡착특성)

  • Lee, Jong-Jib;Um, Myeong-Heon
    • Clean Technology
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    • v.18 no.3
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    • pp.312-319
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    • 2012
  • Malachite green is used a dye but malachite green is harmful toxic substance. In this study, the adsorption characteristics of zeolite has been investigated for the adsorption of malachite green dissolved in water. The effects of initial dye concentration, contact time, pH and temperature on adsorption of malachite green by a fixed amount of zeolite have been studied in batch adsorber and fixed bed. The adsorption equilibrium data are successfully fitted to the Freundlich isotherm equation in the temperature range from 25 to $45^{\circ}C$. The estimated values of k and ${\beta}$ are 23.60-46.88, 0.225-0.347, respectively. The mechanism of the adsorption process was determined from the intraparticle diffusion model. The effects of the operation conditions of the fixed bed on the breakthrough curve were investigated. When the inlet concentration and initial flow rate of malachite green are increased, the corresponding adsorption breaktime appears to decrease. Breaktime increased with increasing bed height and length of adsorption zone showed similar patterns.

A Study on Variations in Physical Properties and Color of Hair depending on Dye Type and Perm, Hair Coloring Treatment Procedure (염모제 종류와 시술 순서에 따른 모발의 물리적 형태와 색의 변화)

  • Park, Yong;Kweon, Soo-Ae
    • Korean Journal of Human Ecology
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    • v.16 no.5
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    • pp.1051-1059
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    • 2007
  • This study intends to find out possible variations in physical properties and color of hair depending on dye type(acidic and alkalic) and permanent treatment/hair dyeing procedure. To meet the goals, healthy hair samples were taken from 5 women's hair speciment in 20's without experiencing in any harmful substance via long-term medications. and beauty care using chemicals. To get possible findings depending upon hair dye type and treatment procedure, both acidic and alkalic hair dye were applied on some specimens after permanent treatment, while on other specimens before permanent treatment. In order to determine scale damage, this study used SEM(Hitachi S-2500C) both hair thickness and tensile strength were measured with optical microscope(Nikon, MM-60/L3T) and Instron (4482-standard). Wave configuration was measured transverse and longitudinal round diameter. The chromaticity of each specimen was measured using a spectrocolorimeter(Color Techno System, JP/JX-777) with visual $C/2^{\circ}$ (at $2^{\circ}$ with C light source) monitor fixed to determine Lab and CMYK values. As a result, it was found that hair specimens were more significantly damaged with alkalic hair dye treatment than with acidic hair dye treatment, while hair specimens were more effectively dyed with the former hair dye type than with the latter one. For possible results depending on treatment procedure, it was found that hair specimens were less damaged but more effectively dyed with permanent treatment followed by hair dyeing than vice versa. Therefore, it was concluded that permanent treatment followed by acidic hair dyeing would be more effective in reducing hair damages.

Development of Metal Compound Explosives Using KIO4 and TiH2 (KIO4와 TiH2를 이용한 금속복합화약 개발)

  • Ahn, Gilhwan;Kim, Sangbaek;Kim, Junhyung;Ryu, Byungtae
    • Journal of the Korean Society of Propulsion Engineers
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    • v.24 no.1
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    • pp.58-63
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    • 2020
  • THPP is a type of metallic complex explosive used in initiators, consisting of TiH2 and KClO4. In this case KClO4 includes ClO4- which is a harmful substance that may cause thyroid dysfunction or tumors. In this study KIO4 is applied to a new type of environmentally friendly explosive as a substitute to the conventional KClO4. Tests were carried out to see if KIO4 can be made a successful replacement for KClO4.