• Clean Technology
• /
• v.10 no.2
• /
• pp.111-120
• /
• 2004

Manufacturing with a chemical for eco-friendly leather for nitrogen decrease of leather falling hair process waste water and the falling hair process that a number to decrease with sulfuration water decrease, a pollution load of COD, BOD. In this study manufactured lining agent and the unhairing assist product which did urea, mercaptan by basic matter. As a result of having dealt in hair saving process, compared, and was recalled by the existing hair burning process recovered hair, increased approximately 2times. Grain state to influence the yield that was quality of leather and an index of productivity evaluation, an improvement of contraction phenomenon (drawing) were possible. Is increased going seal, tear strength property of matter and softness and touch leather native nature in wet blue. Also, it is possible confirmation with decrease being more possible than about 50% COD, T-N density in a hair saving waste water.

• Applied Microscopy
• /
• v.38 no.1
• /
• pp.35-41
• /
• 2008

Onions are commonly available and easily processed, and since their skins are thrown away they could be very useful materials from the viewpoint of environmental preservation. This study aimed to process onion skins into the state of powder and look into the optimum condition for hair dyeing by decoloring virgin hair four times and observing the hair dyeing quality and its mechanical and morphologic changes by the different condition of onion skins in duration, temperature, density, pH, and mordant treatment. The observations of hair surface through scanning microscopy showed the formation of cuticle layer, though in a little blown-up state in the case of the hair dyed with onion skin application, when compared with bleaching hair with the completely dissolved cuticle layer. According to the above findings of experiments, the dyeing quality of the hair dyes with onion skin application was excellent, the dyeing was also feasible without mordants, and the use of Fe as the mordant increased dyeing exhaustion more, which would make it an effective hair dye. These results of the experiments indicate that the natural pigment extracted from onion skins can be actually used for hair dyeing from the viewpoints of the dyeing quality and the skin treatment.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.23 no.5
• /
• pp.1116-1124
• /
• 2009

To determine whether topical application of trimix extracts of Mylabris phalerata Pall., Arisaematis Rhizoma and Pinelliae Rhizoma Ternata lead to affects on the hair growth activity in C57BL/6N mice. To examine the hair growth activity of the extracts of Mylabris phalerata Pall., Arisaematis Rhizoma and Pinelliae Rhizoma Ternata gross, microscopic, and immunohistochemical method were performed. In order to examine the mRNA expression of hair growth related substance, RT-PCR method was performed. Experimental group I on day 14, The most extensive hair growth activity was observed in whole skin area of all the mice whose hair had been clipped. Brdu immunoreactive cells of all the experimental groups were more heavily stained in epidermis, bulge, outer root sheath, inner root sheath, subcutaneous tissue, hair bulb and cutaneous trunci muscles than that of control group on day 12 of hair growing cycle in C57BL/6N mice. VEGF immunoreactive density of all the experimental groups was more heavily stained in epidermis, bulge and cutaneous trunci muscles than that of control group on day 12. FGF and c-kit immunoreactive cells of all the experimental groups were heavily stained in epidermis, outer root sheath, inner root sheath and cutaneous trunci muscles on day 12. PKC-$\alpha$ immunoreactive density of all the experimental groups was mildly stained in epidermis and cutaneous trunci muscles than that of control group on day 12. On day 12, the expression of bFGF (138%, 119%, 120%), VEGF (146%, 144%, 133%), IGF-1 (165%, 141%, 119%) and PLI (121%, 116%, 123&) in each experimental groups was more increased than that of control group. On day 16, The expression of IGF-1 (126%, 149%, 151%) in all the experimental group was more increased than that of control group (100%). The expression of bFGF (92%, 94%) and VEGF (101%, 97%), PL1 (102%, 109%) in all the experimental group was more decreased than that of experimental group I, II on day 12. But the expression of bFGF (109%) and VEGF (127%), and PL1 (105%) in each experimental group III was more increased than that of control group (100%). These experiments suggest that trimix extracts of Mylabris phalerata pall., Arisaematis Rhizoma and Pinelliae Rhizoma Ternata may stimulate the topical hair growth activity and its experimental group I can be useful for treatment of alopecia areata.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.19 no.3
• /
• pp.696-704
• /
• 2005

This experiment examined the effect of Samultang-gamibang (SGB) on hair growth in spontaneous alopecia areata C57BL/6N mice. We first investigated hair growth effect of SGB compare to control groups after apply to oral administration for 10 weeks and regional treatment in skin for last 4 weeks. We second investigated the number of hair follicle and mast cells after treatment of SGB in spontaneous alopecia areata C57BL/6N mice for 10 weeks. We third investigated immunoreactive density of neuropeptides in skin of spontaneous alopecia areata C57BL/6N mice by immunohistochemical methods. The results were as follows : Hair growing effect of experimental group was observed from 7 weeks after administration of SGB (87.5%). In experimental group, the number of mast cells and eosinophils was significantly decreased compare to control group. Immunoreactive density of substance P and corticotropin releasing factor (CRF) in skin of experimental group was weakly stained in epidermis and subcutaneous tissue compare to control group. Immunoreactive density of CRF-receptor (CRF-R), CRF-binding protein (CRF-BP) in skin of experimental group was increased in epidermis, sebaceous gland, inner root sheath, outer root sheath and secondary hair germ epithelium compare to control group. These results suggest that SGB may be used in treatment of alopecia areata.

• Journal of the Korean Society of Industry Convergence
• /
• v.17 no.3
• /
• pp.178-183
• /
• 2014

The objective of this study is to find out the effect of yeast on hair loss treatment and the role of hair follicle stem cell activator, which is important in hair growth. The authors have recently produced a substance, which has no disgusting odor, does not precipitates and does not easily corrupt, to use instead of yeast acquired from raw rice wine(Makgeolli). The substance is named Yeast Constituent Extract(YCE). In this research, the Produced YCE was applied on the hair loss area of 10 Androgenic alopecia patients, twice every day for 6 months, in order to test the effect of hair loss treatment and the role of stem cell activator. As a result, all of the patients showed a significant growth of hair after 3 months of test, and showed much more growing, thickening and strengthening of hair after 6 months. As a result of measuring the number of hair strings in the same scalp region of the patients after 6 months, it is found that the density of hair has increased, indicating that the hair loss treatment was effective. Also the hair follicle stem cell was isolated from the patients and the contents of growth factors (IGF, VEGF, FGF, HGF) derived from hair follicle stem cell were measured with ELISA. As result, the amount is found to be about 10 times greater than before the test. The hair follicle stem cell contains many growth factors that affect growth of hair, so it takes a highly important role in hair loss treatment. The YCE that the authors have produced was found to be effective in increasing the contents of growth factors that are derived from hair follicle stem cell. Thus it can be inferred that the YCE plays a role as a stem cell activator that activates the hair follicle stem cells. In conclusion, the YCE is considered to be highly effective for hair loss treatment and to have a role as a stem cell activator.

• Journal of the Korean Applied Science and Technology
• /
• v.38 no.5
• /
• pp.1273-1281
• /
• 2021

The purpose of this study was to increase the power of color and examine the long-lasting power, which is a disadvantage of one-pack acid hair dye by using chestnut shell pigment. For this, hair dyeing power was measured using a spectrophotometer, the optical density(O.D.) value was measured to examine the degree of fading of the hair, and the elasticity of the hair was analyzed by measuring the tensile strength. As a result of comparing the results of applying different leaving times and treatment methods to the hair samples of each level, the experimental group that was heat-treated for 20 minutes showed the highest dyeing power. Then, it was confirmed in the order of 40 minutes of natural exposure, 10 minutes of heat treatment, and 20 minutes of natural exposure. And it was also confirmed that the color expression visually improved as it went up to level 10. However, at level 10, it was confirmed that some water loss occurred even after 3 days and the tensile strength was low. These findings that indicated the beauty industry will popularize a one-step acid hair dye containing various natural dye ingredients to help maintain modern people's well-being and healthy mind and body.

• Journal of Ginseng Research
• /
• v.45 no.4
• /
• pp.498-509
• /
• 2021

Background: A wide range of environmental factors, such as diseases, nutritional deficiencies, ageing, hormonal imbalances, stress, and ultraviolet (UV) radiation, may affect the structure and function of the skin that covers the entire surface of the human body. In this study, we investigated roles of red ginseng oil (RGO) in enhancing skin functions, including hair growth and skin protection, using mouse models. Methods: For hair growth experiment, shaved dorsal skins of C57BL/6 mice were topically applied with vehicle, RGO, RGO's major compounds, or minoxidil for consecutive 21 days and skin tissues were examined the hair growth promoting capacity. For skin protection experiment, SKH-1 hairless mice were topically applied with vehicle or RGO twice a day for three days prior to exposure to UVC radiation at 20 kJ/cm². Skin tissues were collected to evaluate skin protective effects of RGO. Results: Topical application of RGO to C57BL/6 mice effectively promoted hair regeneration by inducing early telogen-to-anagen transition and significantly increasing the density and bulb diameter of hair follicles. Major compounds, including linoleic acids and β-sitosterol, contributed to RGO-promoted hair growth. Treatment with RGO as well as its major components upregulated expression of hair growth-related proteins. Furthermore, in SKH-1 hairless mice, RGO had a protective effect against UVC-induced skin damage by inhibiting inflammation and apoptosis, as well as inducing cytoprotective systems. Conclusion: These data suggest that RGO may be a potent agent for improving skin health and thereby preventing and/or treating hair loss and protecting skin against UV radiation.

• The Korea Journal of Herbology
• /
• v.34 no.6
• /
• pp.139-146
• /
• 2019

Objective : Recently, hair has become one of the important aspects of beauty. So, there are many studies about prevention and treatment of alopecia. Finasteride and minoxidil have been known to drug for alopecia treatment. However, these agents have side effects such as irritation, pruritus, and erythema when they were used for a long time. So, we assessed hair growth effect on herbal mixture (RAA) include in Rehmanniae Radix Preparata, Achyranthis Radix, and Acanthopanacis Cortex. Methods : 6 weeks aged C57BL/6 mice were divided three treatment groups. : CON group (vehicle solution), MNXD group (positive control, 3% minoxidil), RAA group (15% RAA solution). And we applied 200 ㎕ of three groups to shaved dorsal skin every day. Hair growth effects of treatment were determined through phototrichogram by folliscope and hair follicle morphometry by H&E staining. And we assessed hair growth-related gene (VEGF, IGF-1, TGF-β1) expressions by western blot and 5-α reductase II analysis of dermal (skin) or internal organ (prostate gland). Results : Hair density and hair follicle size in MNXD or RAA group was enhanced compared to those of CON group, respectively. Also, the protein expression levels in dermal of VEGF, IGF-1 increased but TGF-β1 decreased in RAA and MNXD group, compared to CON group, respectively. 5-α reductase II levels of tissues in MNXD or RAA group significantly decreased compared to those of CON group, respectively. Conclusion : These results suggest that RAA has the promoting effect on hair growth.

• Journal of Ginseng Research
• /
• v.33 no.3
• /
• pp.223-228
• /
• 2009

Alopecia is a common form of hair loss in both male and female, affecting approximately ten million Koreans. Although medical treatments have been developed to treat alopecia, these treatments still have limitations due to complications that come with these treatments. In contrast, Korean red ginseng has been shown to have a stimulating effect on hair follicle and it has already been added to hair treatment products as a safe ingredient. This study was conducted to objectively evaluate the efficacy of Korean red ginseng in the treatment of alopecia. 40 patients suffering from androgenic alopecia were recruited and randomly divided into the experimental (20 patients) and control (20 patients) groups. The experimental group took Korean red ginseng extract (3,000 mg/day) for 24 weeks while the control group took a placebo. The changes of hair counts, thickness, and density were evaluated with Folliscope$^{(R)}$. Patient satisfaction was evaluated through a questionnaire, and clinical photographs were rated by dermatologists. The result of the study showed that Korean red ginseng effectively increased hair density and thickness. Patient satisfaction and evaluation of photographs by dermatologists also confirmed the effectiveness of Korean red ginseng in the treatment of alopecia.

• Journal of Digital Convergence
• /
• v.17 no.8
• /
• pp.447-452
• /
• 2019

Modern people are investing a lot of time and economically in their appearance as a means of expressing their aesthetic desires. They have a lot of hair dyes that make up most of their appearance, but their hair damage is serious. Especially, they use hair dyes which are very popular among the hair cosmetics that make up most of their appearance, but their hair damage is serious. The purpose of this study is to investigate the hair tensile strength of hair with oxidative hair dye to induce styling while minimizing hair damage. The results showed that the Max. load, Max. stress, Max. elongation, break load, break stress, break elongation, maximum modulus and tangential modulus according to evaluation interval were significantly different between control and 8N-10N experimental groups. The maximum modulus and tangential modulus for the strain interval did not show tendency to increase or decrease constantly, although there was a difference between the control and experimental group. Therefore this study was conducted to investigate the correlation between hair loss and hair damage through the treatment of high grade oxidative hair dye, which is widely used in ield of industry. We want to provide application data.