• 한국시뮬레이션학회:학술대회논문집
• /
• 한국시뮬레이션학회 2002년도 추계학술대회 논문집
• /
• pp.115-121
• /
• 2002

The growth of semiconductor industry attracted to researchers like design, facility technique and making small size chip areas. But nowadays, cause of technology extension and oversupply and price down, yield improvement is the most important point on growth. This paper describes the computer mode]ing technique as the solutions to analyze the problem, to formalize the semiconductor manufacturing process and to build advanced manufacturing environments. The computer models are built referring an existing 8' wafer production line in Korea.

• 한국작물학회지
• /
• 제25권4호
• /
• pp.91-98
• /
• 1980

Three kinds of shading materials, styrol-foam board, pine board and polytex, were examined and compared with ordinary shading, and the effects of light intensity and the temperature under the shadings on the photosynthesis and the root growth of the Korean ginseng were studied to improve the shading on the ginseng field. The amounts of photosynthesis of the ginseng leaves at 2$0^{\circ}C$ were significantly larger than those at 3$0^{\circ}C$ in the same light intensity. At 2$0^{\circ}C$, the maximum photosynthesis occured at 35, 000 lux, but at 3$0^{\circ}C$, the amount of photosynthesis was rapidly reduced by higher light intensity over 26, 200 lux. The best root growth occurred under the polytex shading and the styrol-foam board shading was also effective for ginseng growth. Under the ordinary shading, the root growth of ginseng planted on rear line was very poor but under the styrol-foam or the polytex shading, the root growth showed little difference between the ginsengs planted on rear line and front line.

• 한국정밀공학회지
• /
• 제21권4호
• /
• pp.161-169
• /
• 2004

In this study, we investigated fatigue crack growth behavior of laser welded sheet metal due to a single overload. Fatigue specimens were made using butt joint of cold rolled sheet metal that was welded by $CO_2$ laser. The fatigue crack propagation tests were performed in such a way that fatigue loading was parallel to the weld line while crack propagation was perpendicular to the weld line. Single overload was applied when fatigue crack tip was arrived near the weld line. The distances between the crack tip and the weld line at which a single overload was applied were 6, 4 and 2mm. The effect of specimen thickness and overload ratio on the fatigue behavior was determined. The plastic zone size of crack tip due to the single overload was determined from the finite element analysis. For investigating fatigue crack growth behavior, we used different thickness specimen 0.9mm and 2.0mm, and variable overload ratio applied fatigue crack propagation test. Also we used finite element analysis for investigating the plastic zone size of crack tip when single overload applied

• 한국양식학회:학술대회논문집
• /
• 한국양식학회 2003년도 추계학술발표대회 논문요약집
• /
• pp.37-37
• /
• 2003

Intraspecific hybrids have been proven to be a useful tool for increase growth rate in some freshwater fish species. However the effects of intraspecific hybrids in seawater fish species is little known. To assess whether intraspecific hybrids in red sea bream was associated with growth enhancement, growth performances of offspring from two inbred lines, selected Korean line (KORDI-F4) and cultured Japanese line (IPN) and two intraspecific hybrids lines (KORDI-F4♀×JPN♂ and JPN♀×KORDI-F4♂) of red sea bream were compared. There's no significant difference in body weight between offspring groups during seed production period (until 4 months old). At seven months old (after three months rearing trials on sea cages communally), the offspring from KORDI-F4 (41.0±11.1g) and JPN♀×KORDI-F4♂ (39.3±8.1g) showed significantly better performance in body weight than that of the offspring from KORDI-F4♀×JPN♂ (37.0±8.1g) and IPN (35.7±9.7g). At 15 months old, the offspring from JPN♀×KORDI-F4♂ showed best growth performances in body weight, weight gain, specific growth rate among four offspring groups. As the results, the intraspecific hybrids between cultured Japanese line and selected Korean line showed superior growth performances than their paternal and maternal inbred lines.

• Biotechnology and Bioprocess Engineering:BBE
• /
• 제10권3호
• /
• pp.254-261
• /
• 2005

The over-expression of Bcl-2 has greatly improved the culture period, specific growth rate, and maximum viable cell density of NS0 cells culture under low serum condition. Further analysis of these data suggests that a saturation model of the Monod type can be used to represent the relationships of specific growth rate and initial serum concentration. The ${\mu}_{max}$ and $K_s$ for the Bcl-2 cell line is $0.927day^{-1}\;and\;0.947\%(v/v)$ respectively, which are $21\%$ greate and $7\%$ lower respectively than its control counterpart. Study on the amino acid supplementation revealed that Bcl-2 cell lines possess greater improvement in the specific growth rate and maximum viable cell density compared to the control cell lines. A further increase in the amino acid supplementation has resulted a $17\%$ decrease in specific growth rate and no improvement in maximum viable cell density in the control culture. However, the Bcl-2 cell line exhibited a better growth characteristic in this culture condition compared to that of control cell lines. The higher specific growth rate and maximum viable cell density of the Bcl-2 cell line in medium fortified with serum and MEM EM suggested a more efficient nutrient metabolism compared to that in the control cell line. The low serum and amino acid utilisation rate and the higher cell yield may prove to be important in the development of serum/protein free culture.

• Natural Product Sciences
• /
• 제15권1호
• /
• pp.1-7
• /
• 2009

This study was performed to investigate the cell growth inhibitory effect of tissue cultured root of wild Panax ginseng C.A. Mayer (tcwPG). The human stomach carcinoma cell line, MKN 74, was incubated with 70% EtOH extract of tcwPG or Panax ginseng C.A. Mayer (PG) for 24 hrs. tcwPG inhibited cell growth at a concentration of $250{\mu}g/ml$. However, Panax ginseng extract did not inhibit cell growth at the same concentration. We also tested the ethyl acetate and $H_2O$ fractions of tcwPG. The inhibitory effect of the ethyl acetate fraction on cell proliferation in MKN 74 cells was more potent than that of the crude extract, and the inhibitory effect of the $H_2O$ fraction was less than that of the ethyl acetate fraction. When we separated tcwPG into polar and non-polar saponin fractions and then measured cell growth inhibition, the non-polar saponin in tcwPG exhibited cytotoxicity. To compare the effects of tcwPG on various cancer cell lines, we measured cytotoxicity in MKN 74 (stomach cancer cell line), SW 620 (colon cancer cell line) and PC 3 (prostate cancer cell line). All three cell lines showed cell growth inhibition, and the cell growth inhibitory effects were not quite different in the various cell lines. The non-polar saponins of tcwPG arrested PC 3 cells at G1-phase as did Panax ginseng.

• 한국가축번식학회지
• /
• 제22권2호
• /
• pp.127-136
• /
• 1998

A chimeric gene comprising murine whey acidic protein(mWAP) and human growth hormone(hGH) was used to produce transgenic rats express hGH and secrete it into the blood. Two lines of transgenic rats carrying the mWAP/hGH construct were established; High line was characterized by relatively high levels of serum hGH, and low line had relatively low levels. The secretory profiles of rat GH(rGH) as well as hGH, the transgene product, were obtained in transgenic males and females of low line; both hGH and rGH serum levels were flattened with no episodic fluctuations, and the overall mean concentration of rGH was significantly lower than in normal littermates. Although the animals of High line showed an acceles, as assessed by vaginal opening and occurrence of first ovulation, advanced by 7∼8 days in both lines of animals. Accordingly, the body weight at puberty of low line transgenic females was much lower than that of normal littermates, indicating that continuous hGH expression could induce precocious puberty without enhancing the growth rate.

• Asian-Australasian Journal of Animal Sciences
• /
• 제29권9호
• /
• pp.1331-1337
• /
• 2016

The aim of this study was to compare the growth performance, fiber characteristics of the pectoralis major muscle, and meat quality characteristics in the heavy weight (HW) and random bred control (RBC) quail lines and genders. The HW male exhibited more than two times greater body (245.7 vs 96.1 g, p<0.05) and pectoralis major muscle (PMW; 37.1 vs 11.1 g, p<0.05) weights compared to the RBC female. This growth performance in the HW line was associated with a greater muscle fiber area (1,502 vs $663.0{\mu}m^2$, p<0.001) compared to the RBC line. Greater muscle mass of the HW male was accompanied by a higher percentage of type IIB fiber compared to the HW female (64.0% vs 51.0%, p<0.05). However, muscle fiber hyperplasia (increase in fiber number) has had a somewhat limited effect on PMW between the two lines. On the other hand, the HW line harboring a higher proportion of type IIB fiber showed rapid pH decline at the early postmortem period (6.23 vs 6.41, p<0.05) and lighter meat surface (53.5 vs 47.3, p<0.05) compared to the RBC line harboring a lower proportion of type IIB fiber. There were no significant differences observed in the measurement of water-holding capacity including drip loss (2.74% vs 3.07%, p>0.05) and cooking loss (21.9% vs 20.4%, p>0.05) between the HW and RBC lines. Therefore, the HW quail line developed by selection from the RBC quail, was slightly different in the meat quality characteristics compared to the RBC line, and a marked difference was found in growth performance between the two quail lines.

• 한국잠사곤충학회지
• /
• 제39권2호
• /
• pp.174-179
• /
• 1997

The larval head capsule width, larval weight and length of mulberry longicorn beetle, Apriona germari Hope were measured when the larvae were exuviated in artificial diet rearing. The larval head capsule width from the 1st to the 12th instar was ranged from 0.12 to 0.69 cm, and growth ratio of each instar was significantly high between the 1st and the 2nd instars. The fitness to Dyar's law for the larval head capsule width was 87.6%. When the logarithum of the larval head capsule width is plotted against the number of instars, the calculated regression line was LogY=0.12086+0.06998X and Dyar's constant was 1.18. The larval weight was increased with larval developmental stages, and the coefficient of variation of larval weight was apparently high. But the calculated regression line was LogY=-0.91592+0.25959X and Dyar's constant was 1.25. The growth ration of the larval length was clearly high between the 2nd and the 3rd instars, and that of larvae from the 4th instar was decreased. The calculated regression line was LogY=-0.16932+0.09841X and Dyar's constant was 1.25. In conclusion, our results suggested that the larvae growth of mulberry longicorn beetle appeared to be highly related in the larval head capsule width, larval weight and length.

• 한국진공학회지
• /
• 제7권3호
• /
• pp.214-220
• /
• 1998

낮은 평형압력을 가진 TDEAT 증착원을 이용하여 TiN증착을 실시한 실험에서 TiN 증착률에 영향을 주는 인지들에 대하여 연구를 실시하였다. TiN성장률은 bubbler 온도, 증 착온도, 운반기체관의 conductance, 운반기체 종류에 따라 큰 영향을 받고 있었다. 또한 bubbler로 유입되는 운반기체관의 가열에 의하여도 증착률 증가가 적은 범위에서 이루어지 고 있음이 관찰되었다. 이와함께 chamber내로 유입되는 운반관을 $90^{\circ}C$로부터 $120^{\circ}C$로 가열 한 실험에 의하면 운반관 가열이 TiN 성장 증가를 일으키고 있으며, 온도에 대한 TiN 성장 은 약0.2eV의 활성화에너지를 가진 Arrehenius형태로 증가되고 있었다.