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Relationships between Structural Features and Biological Activities of HC-toxin

  • Kim, Shin-Duk
    • BMB Reports
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    • v.28 no.3
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    • pp.227-231
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    • 1995
  • In order to figure out the relationships between structural features and biological activity of the host-specific HC-toxin in maize, structurally related cyclic tetrapeptides, chlamydocin and CYL-2 were isolated, and their biological activities in maize were examined. Biological activities of preparations were determined by root growth inhibition and electrolyte leakage bioassays. Chlamydocin and CYL-2 showed toxicities to maize. However, the toxicities of these compounds were non-specific. Thus, the precise peptide ring structure of HC-toxin apparently does not play an important role in toxicity, while resistance of maize to HC-toxin is based on a precise ring conformation.

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Age and Growth of the Asian Clam Potamocorbula ustulata ustulata (Reeve, 1844) on the West Coast of Korea (한국 서해산 쇄방사늑조개, Potamocorbula ustulata ustulata (Reeve, 1844) 의 연령과 성장)

  • Ryu, Dong-Ki;Kim, Yeong-Hye
    • The Korean Journal of Malacology
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    • v.23 no.1
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    • pp.17-23
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    • 2007
  • Samples of Potamocorbula ustulata ustulata were collected monthly from October 2004 to November 2005 in the Jujin estuary of Gochang, Chollabuk-do, west coast of Korean peninsula. Age of P. ustulata ustulata was determined by the rings on the shell. The relationship between the shell length and the ring diameter in each ring group was expressed as a regression line. Therefore, there is a correspondence in each ring formation. Based on the monthly variation of the marginal index (MI') of the shell, it is assumed that the ring of this species was formed once a year during October to December. The relationship between the shell length (SL) and the shell height (SH; mm) was highly correlated with shell height as the following equation: SH = 0.6438 SL + 0.5642 ($r^2\;=\;0.978$). The shell length (SL) - shell width (SW) relation was also expressed by the following equation: SW = 0.4352 SL - 0.5675 ($r^2\;=\;0.957$). Shell length (SL; mm) and the total weight (TW; g) followed: $TW\;=\;6.999\;{\times}\;10^{-5}\;SL^{3.2542}(r^2\;=\;0.975)$. Growth curves for the shell length and the total weight fitted to the von Bertalanffy's growth curve were expressed respectively as: $$SL_t=30.77[1-e^{-0.4572(t+0.7371)}],\;TW_t=4.87[1-e^{-0.4572(t+0.7371)}]^{3.2542}.$$

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Correlation of Growth Performance with Total Nitrogen, Carbon and Nitrogen Isotope Compositions in the Xylem of Pinus koraiensis (잣나무 생장과 목질부내의 전질소, 탄소 및 질소 동위원소 조성과의 상관관계)

  • Lee, Wi-Young;Park, Eung-Jun;Han, Sang-Urk
    • Journal of Korean Society of Forest Science
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    • v.99 no.3
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    • pp.353-358
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    • 2010
  • In this study, we investigated the relationship of tree-ring growth with total nitrogen content, and stable carbon and nitrogen isotopes from the core samples of Pinus koraiensis (35-year-old). Annual ring width showed significant positive correlations with the ${\delta}^{13}C$ (P=0.003). The total nitrogen content (P=0.024), and the ${\delta}^{13}C$ content was also correlated with total nitrogen content (P=0.038), indicating that the growth of P. koraiensis was stimulated as the contents of both ${\delta}^{13}C$ and total nitrogen were increased. On the other hand, the less the ${\delta}^{15}N$ content and the C/N ratio were, the larger the annual ring width was. Moreover the families with relatively better growth performance contained the higher levels of ${\delta}^{13}C$ in the xylem compared to other families. These results suggest that the ${\delta}^{13}C$ and total nitrogen contents are the important determinants in the growth performance of P. koraiensis.

Age and Growth of the Hard Clam, Meretrix lusoria (Bivalvia: Veneridae) on the West Coast of Korea (한국 서해산 백합, Meretrix lusoria의 연령과 성장)

  • Ryu, Dong-Ki;Chung, Ee-Yung;Kim, Yong-Min
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.11 no.4
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    • pp.152-157
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    • 2006
  • Samples of Meretrix lusoria were collected monthly from the tidal flat of Simpo, Puan-gun, Chollabuk-do, west coast of Korea from April 2004 to March 2005. Age of M. lusoria was determined from the rings on the shell. The relationship between shell length and ring radius in each ring group was expressed as a regression line. Therefore, there is a correspondence in each ring formation. Based on the monthly variations in the marginal index (MI') of the shell, it is assumed that the ring of this species was formed once a year during the period of February to April. The relationship between shell length (SL) and shell height (SH; mm) was highly correlated with shell height as the following equation: SH = 0.8103 SL + 0.5145 $(r^2=0.991)$. The shell length (SL) - shell width (SW) relation was also expressed by the following equation: SW = 0.4897 SL + 0.0315 $(r^2=0.976)$. Shell length (SL; mm) and total weight (TW; g) was expressed by the following equation: $TW=2.9195\times10^{-4}\;SL^{2.9547}\;(R^2=0.991)$. Shell length (SL) and shell height (SH; mm) was highly correlated with shell height as the following equation: $SH=0.8103\;SL+0.5145\;(R^2=0.991)$ The shell length (SL) - shell width (SW) relation was also expressed by the following equation: $SW=0.4897\;SL+0.0315\;(R^2=0.976)$. Growth curves for shell length and total weight fitted to the von Bertalanffy's growth curve were expressed respectively as: $SL_t=104.9[l-e^{-0.2235(t+0.7677)}],\;TW_t=280.8[l-e^{-0.2235(t+0.7677)}]^{2.9547}$.

Age and Growth of the Goldeyes Rockfish Sebasetes thompsoni in the Ulleungdo and Dokdo Areas (울릉도 및 독도 근해의 불볼락(Sebastes thompsoni)의 연령과 성장)

  • Heo, Yo Won;Lee, Jae Bong;Yang, Jae Hyeong;Cha, Hyung Kee;Kim, Jung Jin;Zhang, Chang Ik
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.48 no.6
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    • pp.929-939
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    • 2015
  • We studied the characteristics of age and growth of the Goldeyes rockfish Sebasetes thompsoni in the Ulleungdo and Dokdo areas by using 730 otoliths from February 2013 to February 2014. The lowest value of the marginal index was found in June once a year. The spawning period was estimated as April. Therefore, the duration from fertilization to the complete formation of the first annual growth ring is fourteen months. From the parameters calculated using the weighted average length of the year ring formation, the growth of S. thompsoni was demonstrated by the von Bertalanffy growth equation as $L_t=34.68(1-e^{-0.2113(t+0.7683)})$ for females and $L_t=29.79(1-e^{-0.2163(t+1.7964)})$ for males, $L_t=32.84(1-e^{-0.25(t+0.57)})$ for combined sex. Comparing with growth performance index(${\Phi}$) from these 4 offshore areas, parameter of S. thompsoni in Ulleungdo area was 2.4087, that of in Tong-yeong was 2.2835, that of in Aomori was 2.4077 and in Niigata was 2.3927. As a result, the value of Dokdo and Ulleungdo areas showed the highest.

BETTI NUMBERS OVER ARTINIAN LOCAL RINGS

  • Choi, Sangki
    • Bulletin of the Korean Mathematical Society
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    • v.31 no.1
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    • pp.35-44
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    • 1994
  • In this paper we study exponential growth of Betti numbers over artinian local rings. By the Change of Tor Formula the results in the paper extend to the asymptotic behavior of Betti numbers over Cohen-Macaulay local rings. Using the length function of an artinian ring we calculate an upper bound for the number of generators of modules, this is then used to maximize the number of generators of sygyzy modules. Finally, applying a filtration of an ideal, which we call a Loewy series of an ideal, we derive an invariant B(R) of an artinian local ring R, such that if B(R)>1, then the sequence $b^{R}$$_{i}$ (M) of Betti numbers is strictly increasing and has strong exponential growth for any finitely generated non-free R-module M (Theorem 2.7).).

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Radiopharmaceuticals for Imaging of Cellular Proliferation (세포 증식 영상용 방사성의약품)

  • Oh, Seung-Jun
    • The Korean Journal of Nuclear Medicine
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    • v.36 no.4
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    • pp.209-223
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    • 2002
  • By considering the biological properties of a tumor, it should be possible to realize better results in cancer therapy. PET imaging offers the opportunity to measure tumor growth non-invasively and repeatedly as an early assessment of response to cancer therapy. Measuring cellular growth instead of energy metabolism showed offer significant advantages in evaluating therapy. Thymidine and its derivative nucleoside compounds can be changed to mono, di- and tri- phosphate compounds by thymidine kinase and then be incorporated into DNA. Their bindings are increased in highly proliferating cells due to the high DNA synthesis rate. To evaluate cell proliferation, many kinds of thymidine and uridine derivatives have been labeled with positron emitter and radioactive iodine. Compared to radiopharmaceuticals which have radioisotope labeled base ring such as pyirmidine, the radiopharmacuticals which have radioisotope labeled sugar ring are more stable in vivo and have metabolic resistance. The biological properties such as DNA incorporation ratios are highly dependent on their chemical structures and metabolic processes. This overview describes synthesis of radiopharmaceuticals and their biological properties for imaging of tumor cell proliferation.

Physical and Mechanical Properties of Korean Red Pine Wood from Different Growth Sites and Correlations between Them (생장지역별 소나무재의 물리적·역학적 특성과 상호 상관관계)

  • Han, Yeonjung;Lee, Hyun-Mi;Eom, Chang-Deuk
    • Journal of the Korean Wood Science and Technology
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    • v.44 no.5
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    • pp.695-704
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    • 2016
  • Physical and mechanical properties of Korean red pine wood grown in Anmyeon-do, Taean-gun, Chungcheongnam-do and Sogwang-ri, Uljin-gun, Gyeongsangbuk-do, Korea were measured and each relationships between them were analyzed. The ring width and latewood proportion along radial axis in Korean red pine at two-regions were measured by collecting the growth core of stands with age class V and IX. The ring width in Korean red pine at two-regions decreased with increasing cambium age. The average ring widths in age class V and IX in Anmyeon-do and Sogwang-ri were 2.865 mm, 1.705 mm, 4.764 mm, and 2.228 mm, respectively. The ring widths in Anmyeon-do were measured from 23% to 40% smaller than Sogwang-ri. The latewood proportion was negatively related with the ring width of Korean red pine at two-regions. The relationship between physical and mechanical properties of specimens for compressive and bending strength tests were analyzed with simple regression analysis. The relationship between latewood proportion and oven-dry density were positive and statistically significant. The relationship between latewood proportion and mechanical properties was slightly positive and not statistically significant, except the specimens for bending strength test of Anmyeon-do. The relationship between oven-dry density and mechanical properties was positive. It was just statistically significant in the specimens of Sogwang-ri. The compressive and bending strengths of Anmyeon-do and Sogwang-ri were 51.3 MPa, 80.5 MPa, 37.7 MPa, and 63.7 MPa, respectively. The strength difference between two-regions was determined to due to difference of ring width and latewood proportion by age class.

Annual Ring Formation of Major Wood Species Growing in Chuncheon, Korea(I) - The Period of Cambium Activity - (춘천지역에서 생장하는 주요 수종의 연륜형성(I) - 형성층 활동기간에 관하여 -)

  • Kwon, Sung Min;Kim, Nam Hun
    • Journal of the Korean Wood Science and Technology
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    • v.33 no.4 s.132
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    • pp.1-8
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    • 2005
  • The initiation and cessation of cambial activities were investigated to find out the growth characteristics of the major species growing in Chuncheon, Korea. The division of cambial zone in Pinus densiflora and Pinus koraiensis began from the middle of March through the end of March. The activity of cambial zone in P. densiflora and P. koraiensis was vigorous from the end of May through the middle of July. During this period the number of cells increased rapidly in radial direction. However, the number of cells in P. densiflora was gradually increased. The division of cambial zone in ring-porous wood, such as Quercus mongolica and Robinia pseudoacacia began in the middle of March, before the formation of vessel. The division of cambial zone in diffuse-porous wood, such as Cornus controversa and Prunus sargentii, began in early April, and then the formation of vessels began after one to three weeks. It was considered that the cambial zone in softwood was ceased from the beginning of November, whereas cambial activities in hardwood ceased in the middle of October. Consequently, the formation of growth ring was different among the species, even though the trees were grown under the same conditions.

Hydrogel Ocular Inserts for the Treatment of Infectious Bovine Keratoconjunctivitis

  • Ryoo, Je-Phil;Greer, R.T.;Rosenbusch, R.F.
    • Journal of Pharmaceutical Investigation
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    • v.22 no.3
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    • pp.35-47
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    • 1992
  • Hydrogel coated ring shaped ocular inserts (containing the antibiotic, tylosin tartrate) were used in an evaluation of the effectiveness of polymeric ocular drug release devices for treating infectious bovine keratoconjunctivitis. The in vivo experiments represent the first experiments using hydrogel ocular inserts containing an antibiotic for treating infectious bovine keratoconjunctivitis. In the infection tests, ten calves. were challenged with $2.4{\times}10^8{\sim}1.6{\times}10^9$ Moraxella bovis (a bacterium) colonies per eye following two ten minute ultraviolet radiation eye preconditioning exposures. Ninety five percent of the eyes (19 of 20 eyes) were successfully infected by this method. All infected eyes were monitored for the presence of the bacteria quantitiatively, and clinical observations were made for 14 days. The test was performed by three consecutive steps: 1) inoculation with 2 ultraviolet (UV) radiations, 2) growth of bacterial colonies and 3) treatment with medicated ring-shaped devices. The first. bacteriological measurements after 2 UV exposures were performed at day 3 of the tests. At day 7 after inoculation of both eyes of a calf with M. bovis, a medicated or a non-medicated ring-shaped device was inserted into each eye of a calf. The eye receiving the non-medicated ring was taken as a control for comparison with the eye that received a medicated ring. During the next 7 day period following a medicated ring insertion, the number of bacteria in the treated eyes dropped dramatically to negligible levels (0 to 30 colony forming units/swab), while the control eyes which received a non-medicated ring still exhibited a relatively high number of bacteria ($10^3\;to\;10^6$ colony forming units/swab). The number of bacteria was significantly reduced by the antibiotic released from the medicated ocular insert.

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