• 한국프랜차이즈경영연구
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• 제12권2호
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• pp.23-33
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• 2021

Purpose: The purpose of this study is to provide basic data such as development of sustainable support policies and performance management evaluation to support sustainable management of domestic franchises by deriving the sustainable growth cycle of domestic franchises. Research design, data, and methodology: This study is based on systematic review study. We combined search terms such as "Start-up", "Sustainability" and "Success" with four databases, RISS, KISS, e-article and DBpia and searched a total of 1,219 articles published by April 21, 2021. In the process, 35 studies were selected and analyzed after an expert review, excluding documents whose overlapping documents, gray zones (e.g., reports, conference presentations, etc.), degree papers, foreign language literature, and dependent variables were not related to the Sustainability factors. Using ERIS model, which is applied to research on the results of startup, and the franchise's growth cycle, which reflects the growth stage of franchises, we analyzed the factors behind the sustainability of franchise. Result: The results of the study are as follows. First, research on the sustainability of franchise has continued since 2009 in Korea, and has been conducted in various fields such as social welfare in addition to venture, start-up and management. Second, sustainability factors of franchise were analyzed from the ERIS performance model indicating the performance of venture, and the 68 subfactors were derived. Third, it is confirmed that there are important factors that affect the sustainable growth of franchise startups in each franchise's growth cycle. Conclusions: It is significant that through this study, we provided better understanding of the factors that sustain sustainability of franchises, policy suggestions, and presented the direction of future study. Theoretical suggestion is that the main reason for the continuous growth of franchise in each domestic franchise is based on the ERIS performance model. The practical implication is that the headquarters and Franchisor can use it to establish and evaluate performance indicators based on the business growth cycle. The results of this study are expected to be used as basic data for development and performance management evaluation of franchise start-up support policies to support the sustainable management of domestic franchises.

• 임상간호연구
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• 제29권1호
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• pp.85-94
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• 2023

Purpose: The purpose of this study was to investigate the influencing factors of post-traumatic growth in patients with gastrointestinal cancer. Methods: A cross-sectional study was conducted, enrolling 120 patients with gastrointestinal cancer. Their general characteristics, disease-related characteristics, perceived illness intrusiveness, levels of optimism, social support, and post-traumatic growth were assessed through self-administered questionnaires. The collected data were analyzed using descriptive statistics, independent t-test, oneway ANOVA, Pearson's correlation, and multiple regression analysis. Results: The mean score of post-traumatic growth was 52.74 points(total score of 92 points). Among the subscales of post-traumatic growth, levels of the preciousness of life were the highest, and relating with others was the lowest. The post-traumatic growth was found to be significantly correlated with optimism (r=.48, p<.001), social support (r=.47, p<.001), and depression (r=-.37 p<.001). Factors associated with post-traumatic growth were optimism (β=.36, p<.001), social support (β=.31, p<.001), and depression (β=-.27, p<.001). Conclusion: Given that prevalence of gastrointestinal cancer is increasing in Korea, identifying general, psychological, and social factors affecting post-traumatic growth among this population will be helpful in clinical practice. Integrated strategies to increase optimism and social support and lower depression should be considered to improve the post-traumatic growth of patients with gastrointestinal cancer.

• 한국농림기상학회지
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• 제8권3호
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• pp.145-151
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• 2006

우리나라 중북부의 산림에서 참나무류의 연년 직경생장 변화와 온도, 강수량, 일조량 등 기상요인과의 관계를 분석하였다. 연년직경생장은 262개의 참나무에서 채취한 생장편을 이용하여 측정하였다. 참나무류의 연년직경생장은 월악산보다 중왕산에서 더 좋았으며, 종별로는 졸참나무>굴참나무>신갈나무>떡갈나무 순으로 크게 나타났다. 월악산과 중왕산 두 지역간의 참나무류 생장패턴은 서로 달랐으며, 중왕산에서는 참나무류의 직경생장이 7월의 기온이나 일조량과 양의 상관관계가 있는 것으로 나타났다. 그러나 월악산에서는 3월의 일조량과 6월의 강수량이 연륜생장과 유의한 양의 상관이 있는 것으로 나타났다. 같은 지역의 산림내에서 참나무류의 직경생장에 영향을 미치는 기상조건이 같아도 해발고, 지형, 토심과 같은 식생환경에 따라 기상인자의 영향정도가 다른 것으로 추정된다.

• Asian-Australasian Journal of Animal Sciences
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• 제8권1호
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• pp.51-58
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• 1995

To examine whether colostral growth factors are transferred to the general circulation, concentrations of plasma cortisol, insulin, prolactin, growth hormone, insulin-like growth factors(IGFs) -I and -II, IGF-binding proteins(IGFBPs) and total protein were measured in newborn calves fed colostrums, milk of milk replacer before and after feeding at 12 h intervals during the first two days after birth. Plasma protein concentrations increased with time after than in milk- or milk replacer-fed calves. The mean protein concentration was greater in colostrum-fed than in milk- or milk replacer-fed calves. Plasma cortisol levels transiently declined after each feeding regardless of the type of diet, while insulin levels tended to increase. Mean concentrations of these hormones did not differ between dietary groups, nor did they change with time after birth. Plasma concentrations of prolactin and growth hormone did not differ between dietary groups and also did not change with time after birth or after feeding. Concentrations of IGF-I and IGF-II transiently increased at the second feeding period, but these, as well as plasma IGFBP profiles, were not different between groups or before and after feeding. Results did not indicate significant transfer of colostral growth factors across the newborn ruminant small intestine.

• Journal of Korean Neurosurgical Society
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• 제44권6호
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• pp.375-381
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• 2008

Objective : The effects on neural proliferation and differentiation of neural stem cells (NSC) of basic fibroblast growth factor-2 (bFGF). insulin growth factor-I (IGF-I). brain-derived neurotrophic factor (BDNF). and nerve growth factor (NGF) were assessed. Also, following combinations of various factors were investigated : bFGF+IGF-I, bFGF+BDNF, bFGF+NGF, IGF-I+BDNF, IGF-I+NGF, and BDNF+NGF. Methods : Isolated NSC of Fisher 344 rats were cultured with individual growth factors, combinations of factors, and no growth factor (control) for 14 days. A proportion of neurons was analyzed using $\beta$-tubulin III and NeuN as neural markers. Results : Neural differentiations in the presence of individual growth factors for $\beta$-tubulin III-positive cells were : BDNF, 35.3%; IGF-I, 30.9%; bFGF, 18.1%; and NGF, 15.1%, and for NeuN-positive cells was : BDNF, 34.3%; bFGF, 32.2%; IGF-I, 26.6%; and NGF, 24.9%. However, neural differentiations in the absence of growth factor was only 2.6% for $\beta$-tubulin III and 3.1% for NeuN. For $\beta$-tubulin III-positive cells, neural differentiations were evident for the growth factor combinations as follows : bFGF+IGF-I, 73.1 %; bFGF+NGF, 65.4%; bFGF+BDNF, 58.7%; BDNF+IGF-I, 52.2%; NGF+IGF-I, 40.6%; and BDNF+NGF, 40.0%. For NeuN-positive cells : bFGF+IGF-I, 81.9%; bFGF+NGF, 63.5%; bFGF+BDNF, 62.8%; NGF+IGF-I, 62.3%; BDNF+NGF, 56.3%; and BDNF+IGF-I, 46.0%. Significant differences in neural differentiation were evident for single growth factor and combination of growth factors respectively (p<0.05). Conclusion : Combinations of growth factors have an additive effect on neural differentiation. The most prominent neural differentiation results from growth factor combinations involving bFGF and IGF-I. These findings suggest that the combination of a mitogenic action of bFGF and post-mitotic differentiation action of IGF-I synergistically affects neural proliferation and NSC differentiation.

• 한국벤처창업학회:학술대회논문집
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• 한국벤처창업학회 2006년도 추계학술발표회
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• pp.197-217
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• 2006

본 연구는 수출을 기반으로 성장을 하는 우리나라 벤처 기업의 수출성장에 미치는 영향요인을 분석하는 것을 목적으로 한다. 기존 연구에 대한 문헌조사를 통하여 수출과 관계된 기업의 존속여부와 성장성(매출액 성장성)은 기업내부의 여러 가지 요인 및 기업을 둘러싸고 있는 외부적 환경과의 일정한 상관관계와 인과관계의 틀 속에서 기업의 존속여부와 성장성(수출액 성장성)이 결정된다고 생각할 수 있다. 또한 기업을 둘러싸고 있는 외부적환경은 기업 스스로의 힘과 의지에 의해서 통제될 수 없는 부분이라고 생각할 수 있는바 기업의 존속여부와 성장성(수출액 성장성)은 기업내부의 요인에 의하여 결정된다고 판단 할 수 있다. 기업의 성장성(수출액 성장성)을 결정하는 중요한 요인에는 어떤 것이 있으며 그러한 요인이 어느 정도의 영향력으로 기업의 성장성(수출액 성장성)에 영향력을 미치는가를 요인간의 모형으로 설정하고자 한다.

• 한국시스템다이내믹스연구
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• 제10권3호
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• pp.47-79
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• 2009

The paper examines dynamic relationship among 'Limit to Growth' factors in Korea using causal loop diagram. It also aims to explore policy implications for Korea in overcoming current difficulties and future crisis we may face. For this purpose, five factors -economy, population, resource, environment, food- used in the were adopted as an analytical framework. Findings show that Korea is fragile to external shock such as world economic crisis, food price surge, and resource price -including energy price- hike. High dependency of energy, food and resource on foreign market was found to be a major source of limit to growth in Korea. Furthermore, environmental problems like global warming could be a major external shock that could hit Korea harder than the rest of the world. Policy implications and measures for these problems were discussed too.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권6호
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• pp.616-621
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• 2008

Osseointegration is a result of bone formation and bone regeneration processes, which takes place at the interface between bone and implant, and it indicates a rigid fixation that can be stably maintained while functional loading is applied inside the oral cavity as well as after implant placement. Although many researches were carried out about osseointegration mechanism, but cellular and molecular events have not been clarified. With recent development of molecular biology, some researches have examined biological determinants, such as cytokine, growth factors, bone matrix proteins, during osseointegration between bone and implant surface, other researches attempted to study the ways to increase bone formation by adhering protein to implant surface or by inserting growth factors during implant placement. Cellular research on the reaction of osteoblast especially to surface morphology (e.g. increased roughness) has been carried out and found that the surface roughness of titanium implant affects the growth of osteoblast, cytokine formation and mineralization. While molecular biological research in dental implant is burgeoning. Yet, its results are insignificant. We have been studying the roles of growth factors during osseointegration, comparing different manifestations of growth factors by studying the effect of osseointegration that varied by implant surface. Of many growth factors, $TGF-{\beta}$, IGF-I, BMP2, and BMP4, which plays a significant role in bone formation, were selected, and examined if these growth factors are manifested during osseointegration. The purpose of this article is to present result of our researches and encourage molecular researches in dental implant.

• Asian-Australasian Journal of Animal Sciences
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• 제16권3호
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• pp.335-341
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• 2003

Carcass weight and backfat thickness are two of important elements in determining the carcass trait in pigs and are studied on animal genetics, nutrition, and endocrinology. Growth factors stimulate or inhibit the proliferation and differentiation of various cells. In particular, insulin-like growth factors (IGFs), transforming growth factor (TGF)-$\beta$, and epidermal growth factor (EGF) are involved in the growth and maintenance of muscle. Also, dehydroepiandrosterone-sulfate (DHEA-S) and cortisol are known to be related to the obesity and subcutaneous fat depth in pigs. Therefore, this study was performed to relate growth factors (IGFs, TGF-${\beta}1$, and EGF) and hormones (cortisol and DHEA-S) concentrations at antemortem and postmortem periods to carcass traits including carcass weight and backfat thickness. Blood and m. Longissimus were collected in pigs at antemortem (30 days before slaughter) and postmortem periods. After slaughtered, carcass weight and backfat thickness were measured. Growth factors and hormones in serum and m. Longissimus were measured by radioimmunoassay or enzyme-linked imuunosorbent assay. Before antemortem period, serum IGF-I and -II concentrations were positively correlated with the carcass weight and backfat thickness in gilts, and the concentrations of TGF- ${\beta}1$ and cortisol in barrows show the correlation with only carcass weight. Also, the positive correlations of muscular IGFs and TGF-${\beta}1$ at postmortem 45 min with the carcass weight and backfat thickness were detected. Consequently, these results suggest that the serum and muscular endocrine factors are involved in the carcass weight and backfat thickness in pigs.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 1998년도 춘계학술대회논문집
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• pp.28-31
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• 1998

Wrinkling is one of the major defects in sheet metal products and may be also attributable to the wear of the tool. The initiation and growth of the wrinkles are influenced by many factors such as stress state, mechanical properites of the sheet material, geometry of the body, and contact condition. It is difficult to analyze the wrinkling initiation and growth considering the factors because the effects of the factors are very complex and the wrinkling behavior may show wide variation for small deviation of the factors. In this study, the bifurcation theory is introduced for the finite element analysis of wrinkling initiation and growth, All the above mentioned factors are conveniently considered by finite element method. The finite element formulation is based on the incremental deformation theory and elastic-plastic material modeling. The finite element analysis is carried out using the continuum-based resultant shell elements considering the planar anisotropy of the sheet metal. The proposed method is verified by employing to column buckling problem. And then, the initiation and growth of wrinkling in deep drawing of cylindrical cup are analyzed.