• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.2
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• pp.133-144
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• 2020

The purpose of this study was to examine the effects of an elderly people's health promotion program performed in a senior center located in J-si. Most interesting were the effects on the physical, physiological, and psychological parameters for senior center participation of the elderly. A nonequivalent control group pre-posttest design was employed. A total of 41 people living in J-si were assigned to either an experimental group (n=21) or control group (n=20). The experimental group was provided with the eight-week elderly people's health promotion program from May 1 to September 2 in 2019. The data were analyzed using SPSS/WIN 24.0 using descriptive statistics, 𝒙²-test, Fisher's exact test, and t-test. The results indicated a significant difference between the experimental group and control group with respect to the scores of the physical parameters, including right grip strength (t=-3.01, p=.004) and flexibility of the waist (t=-2.11, p=.09); the physiological parameters, including the systolic blood pressure (t=-3.02, p=.004); and psychological, including depression (t=2.42, p=.020), hopelessness (t=5.22, p<.001), and quality of life (t=4.28, p<.001). Therefore, the elderly people's health promotion program with senior center participation of the elderly is a useful nursing intervention program that can improve the right grip strength, flexibility waist, reduce the systolic blood pressure, depression and hopelessness, and improve the quality of life.

• Biomolecules & Therapeutics
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• v.26 no.3
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• pp.298-305
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• 2018

Rhomboid family member 2 gene (Rhbdf2) is an inactive homologue lacking essential catalytic residues of rhomboid intramembrane serine proteases. The protein is necessary for maturation of tumor necrosis factor-alpha ($TNF-{\alpha}$) converting enzyme, which is the molecule responsible for the release of $TNF-{\alpha}$. In this study, Rhbdf2 knockout (KO) mice were produced by CRISPR/CAS9. To see the effects of the failure of $TNF-{\alpha}$ release induced by Rhbdf2 gene KO, collagen-induced arthritis (CIA), which is the representative $TNF-{\alpha}$ related disease, was induced in the Rhbdf2 mutant mouse using chicken collagen type II. The severity of the CIA was measured by traditional clinical scores and histopathological analysis of hind limb joints. A rota-rod test and grip strength test were employed to evaluate the severity of CIA based on losses of physical functions. The results indicated that Rhbdf2 mutant mice showed clear alleviation of the clinical severity of CIA as demonstrated by the significantly lower severity indexes. Moreover, a grip strength test was shown to be useful for the evaluation of physical functional losses by CIA. Overall, the results showed that the Rhbdf2 gene has a significant effect on the induction of CIA, which is related to $TNF-{\alpha}$.

• Korean Journal of Veterinary Research
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• v.50 no.2
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• pp.93-103
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• 2010

This study investigated the potential effects of amitraz on the pre- and postnatal development, behavior, and reproductive performance of offspring of parent rats given amitraz during pre-mating, gestation, and lactation. The test chemical was administered via the drinking water containing 0, 40, 120, and 360 ppm to male rats from 2 weeks before mating to the end of 14-day mating period and to females from 2 weeks before mating, throughout mating, gestation and lactation up to weaning. Based on fluid consumption, the male rats received an average of $0,\;5.7{\pm}1.33,\;13.2{\pm}2.08,$ and $35.8{\pm}3.42$ mg/kg/day amitraz, and the female rats received an average of $0,8.7{\pm}4.42,\;20.1{\pm}9.60,\;and\;47.6{\pm}22.38$ mg/kg/day amitraz, respectively. At 360 ppm, an increase in the incidence of abnormal clinical signs, a suppression in the body weight gain, a decrease in the food consumption and litter size, an increase in the post-implantation loss, and a decrease in the seminal vesicle weight were observed in the parent animals. In addition, a suppression in the body weight gain, a decrease in the grip strength, a delay in the negative geotaxis, an increase in the pre- and post-implantation loss, and a decrease in the number of live embryos were observed in the offspring. At 120 ppm, suppressed body weight gain and reduced food consumption were observed in the parent rats. Suppressed body weight gain and decreased grip strength were also observed in the offspring. There were no signs of either reproductive or developmental toxicity at 40 ppm. Under these experimental conditions, the no-observed-adverse-effect level of amitraz for parent rats and their offspring was estimated to be 40 ppm in rats.

• Therapeutic Science for Rehabilitation
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• v.9 no.4
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• pp.7-20
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• 2020

Objective : This study aimed to investigate the effect of simultaneous application of peripheral nerve sensory stimulation and task-oriented training on the improvement of upper extremity motor function after stroke. Methods : This study included 29 patients with hemiplegia. The 14 subjects were in the peripheral nerve sensory stimulation and task-oriented training group for 4 weeks (30 min/d, 5 d/wk), while the 15 control group subjects underwent only task-oriented training for the same duration. The outcome measures were the percentage of voluntary baseline muscle contractions of the wrist and shoulder and Box and Block Test, grip and pinch strength, and Action Research Arm Test. Results : After 4 weeks, muscle activity of extensor carpi radialis, flexor carpi radialis and grip strength and Action Research Arm Test were significantly higher in the experimental group. Conclusion : Simultaneous application of the peripheral nerve sensory stimulation and task-oriented training was found to be superior to task-oriented training for improving upper extremity motor function of adults with stroke.

• Korean Journal of Community Nutrition
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• v.19 no.2
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• pp.142-162
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• 2014

Objectives: To evaluate the critical environmental factors on healthy-aging of Korean people, we investigated the significant factors influencing health status of septuagenarians living in rural area of Jeonla province, known to be one of the representative longevity regions in Korea. Methods: We divided subjects into healthy group (36M/25F) or poor-health group (26M/73F) based on self-reported health status, body mass index, a number of prescription, and blood test data. General characteristics, physical measurements, lifestyle, dietary behavior and nutrient intake, physical health and mental health data were statistically compared between the two groups. Results: Average age was not different between healthy group and poor-health group in men and women, respectively. In men, significantly favorable factors to health were observed to be higher education, regular exercise, higher grip strength and walking function, body mass index (${\geq}18.5kg/m^2$), moderate frequency of drinking and eating-out, non-smoking, normal red blood cell (RBC) count, higher serum dehydroepiandrosterone-sulfate (DHEAS) level, good digestive function and appetite, normal hearing function, regular meals, adequate vegetable and fruit intake, diverse food intake, adequate energy and nutrients (protein, vitamin $B_1$, $B_6$, C and E, folate, niacin, P, Zn and K) intake, higher mini-nutrient status assessment (MNA) score and low level of depression. On the other hand, in women, those were literacy, living arrangement, moderate frequency of drinking, healthy teeth, higher grip strength and walking function, bone mineral density, normal RBC and white blood cell (WBC) count, higher DHEAS concentration, higher MNA score, normal cognition and memory function, having snack and adequate fruit intake. Conclusions: These results could be useful to plan effective strategies to increase health-life expectancy of Korean old people living in rural areas.

• Journal of The Korean Society of Integrative Medicine
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• v.10 no.2
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• pp.37-47
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• 2022

Purpose : We aimed to investigate the effects of nutritional foods on sarcopenia prevention and physical function among the elderly living in rural communities during the COVID-19 pandemic by providing customized nutrition. Methods : This study was conducted in the rural community of SCC. Participants (n=24, over age 65) were randomly assigned into a Protein group (n=12) and a Vitamin group (n=12). The protein group was given 23 g/d of protein (whey, soybean, BCAA) for 8 weeks and the Vitamin group 23 g/d of vitamin (B, C, D, E and mixed minerals such as calcium, magnesium, zinc) for 8 weeks. All participants had their body composition such as height, weight, skeletal muscle mass, body mass index, and body fat percentage, measured using bioelectrical impedance analysis (BIA) and physical function assessed using grip strength and the short physical performance battery (SPPB). Results : At the end of the intervention, there was a significant increase in skeletal muscle mass (p<.01) in the Protein group (p=.002, 4.92 %) compared to the baseline: it increased by 2.33 %. The Vitamin group had a significant increase in body fat percentage after the intervention (p=.001, 15.35 %) compared to the baseline: body fat percentage decreased by 4.49 %. There were no significant differences in left and right Grip strength/Weight, SPPB, 4-m gait speed, chair stand test, and sense of balance in both groups. Conclusion : The findings from this study suggest that 8 weeks of protein intake have a significant effect on skeletal muscle mass and body fat percentage. Protein intake helped promoting the health of the elderly in rural community during the COVID-19 pandemic. It will assist creating a foundation for providing customized nutrition for the elderly in rural community in the future.

• Science of Emotion and Sensibility
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• v.25 no.1
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• pp.115-128
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• 2022

This study investigates the effect of wrist guards equipped with electronic muscle stimulation on reducing wrist pain and improving wrist function of actual lure fishing participants. This study combined conductive fabrics by selecting two products of wrist guards that can be used in lure fishing, which requires holding fishing rods with hands for a long time. It was conducted on ten healthy men aged 35 to 45, and the selection conditions were selected for those who did not have a history of surgery on the wrist and are currently enjoying lure fishing as a hobby. The experimental movement was performed 100 times before each experiment to cause delayed muscle pain to cause wrist fatigue when lure fishing was performed with the operation of grip strength and range of motion. As a result of this study, it was found that pain reduction, range of motion, and grip strength were improved when electrical stimulation was applied after wearing a wrist band in the form of a wrist wrap and semi-gloves. The conclusion of this study was that when electrical stimulation was applied to the wrist guards, the effect of improving the fatigue and function of the wrist could be confirmed through experiments. Through this study, it is expected that wearing electronic muscle stimulation wrist guards will have a significant effect on preventing wrist injuries and improving functional recovery for lure fishing participants.

• Korean Journal of Exercise Nutrition
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• v.24 no.4
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• pp.34-43
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• 2020

[Purpose] The purpose of this study was to assess changes in blood glucose level, blood pressure, and arterial stiffness after a 75 g oral glucose tolerance test (OGTT) in elderly women aged over 65 years with hypertension and either normal glycemic control, impaired fasting glucose tolerance, or diabetes mellitus. We also wished to investigate the relationship between stages of diabetes and physical fitness. [Methods] A total of 24 elderly women with hypertension were assigned to a control group (CON; n=7), impaired fasting glucose group (IFG; n=9), and diabetes mellitus group (DM; n=8). In each group, blood glucose level, brachial ankle pulse wave velocity (PWV), and blood pressure were measured at baseline as well as 60 and 120 minutes after a 75 g OGTT. Physical fitness factors such as hand grip strength, balance test, 4 m gait speed test, chair stand test, short physical performance battery, and 6-minute walking test were subsequently assessed. [Results] In all three groups, blood glucose levels were significantly increased at 60 and 120 minutes after a 75 g OGTT. In the DM group, blood glucose levels were significantly higher before and after a 75 g OGTT than in the CON group. In the CON group, PWV was significantly increased at 60 minutes after a 75 g OGTT; however, there were no changes in other groups after glucose ingestion. In the CON group, systolic and diastolic blood pressures were significantly decreased at 60 and 120 minutes after a 75 g OGTT compared to baseline. However, there was no change in blood pressure after ingestion in the DM group. The IFG group had greater grip strength than the CON group; however, there were no differences in other variables between the groups. [Conclusion] After a 75 g OGTT, elderly women with hypertension and diabetes maintain higher blood glucose levels compared to those with hypertension alone. Unlike elderly women with hypertension alone, those with hypertension and diabetes did not show changes in arterial stiffness and blood pressure after a 75 g OGTT. Therefore, elderly women with hypertension and diabetes may not be able to control their blood vessels following a 75 g OGTT due to impaired vascular endothelial function. Moreover, there was no association between diabetes stage and physical fitness in elderly women with hypertension.

• Korean Security Journal
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• no.14
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• pp.431-447
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• 2007

The purpose of this study was to investigate the An analysis on the physical strength factor of the Collegians majoring in Security Services. In order to accomplish this purpose, subjects of this study were 80 person J university student men. Physical fitness tests was grip strength, back strength, sit-ups, stand long jump, 50m run, side step test, shuttle run, 2000m run, standing trunk flexion, and closed eye foot balance. Factor analysis applied for analysis factorial structure of each physical fitness components. The results of this study were as follow; First, the factor affecting the performance of the Collegians majoring in Security Services of their was appeared with the Power, Balance and Strength. Second, the factor affecting the performance of the Collegians majoring in Security Services of their was appeared with the Taekwondo major group with the Balance, Power, Strength and Cardiovascular Endurance. Third, the factor affecting the performance of the Collegians majoring in Security Services of their was appeared with the Judo major group with the Power, Flexibility and Strength. Fourth, the factor affecting the performance of the Collegians majoring in Security Services of their was appeared with the Hapkido major group with the Muscular Endurance, Strength, Cardiovascular Endurance and Flexibility. Fifth, the factor affecting the performance of the Collegians majoring in Security Services of their was appeared with the Gumdo major group with the Cardiovascular Endurance and Power.

• Journal of muscle and joint health
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• v.9 no.1
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• pp.28-39
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• 2002

Objective. The 12 forms of Sun-style Tai Chi exercise has been developed specifically for arthritis patients in order to reduce their symptoms and to improve physical functioning. This quasi-experimental study examined the changes in pain, balance, muscle strength and physical functioning in women with osteoarthritis at the completion of the 12 week Tai Chi exercise program. Methods. The patients with osteoarthritis who signed the consent form were screened by their primary physician according to the inclusion criteria and invited to the study. Total of 66 osteoarthritis women with an average age of 63 years were participated in the Tai Chi exercise. At the completion of 12 weeks, 34 patients completed both pretest and posttest measures with 48% of overall dropout rate. Outcome measures were physical symptoms, balance, muscle strength, physical functioning, and depression. Paired t-test was utilized to examine differences between pre and post-measures. Results. After participating in the Tai Chi exercise program, the women with osteoarthritis showed significant improvements in their physical fitness measures, and consequently in their physical functioning. In physical fitness test, there were significant improvements in balance, flexibility, muscle strengths of knee, grip, and back muscles after the Tai Chi exercise. However, No significant differences were found in pain and stiffness of their knee joints and depression measure. Conclusion. The 12 forms of Tai Chi exercise has been found safely applicable to the older women with osteoarthritis for 12 weeks, and effective in improving balance, flexibility, and muscle strengths, and consequently lessening difficulties of performing their activities of daily life.