• 패션비즈니스
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• 제19권5호
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• pp.93-109
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• 2015

By the influence of ageing population, the well-being trend, and the increase of interest in health, people seems to be enjoying sports and outdoor life more. Followed by the change of consumers' life style, the interest in smart clothing grafting scientific technology has increased, and research on this subject is necessary. This study is to develop improved design of band type heating vests by grasping the weak point of currently sold heating vest designed by the manufacturer. Through this process, satisfaction of the consumer and the manufacturer can be increased. The results of this study are as follows: 1) Conducted a demand survey with the manufacturer and wearing evaluation test with the consumer on band type heating vests. 2) Suggested design drafts on band type heating vests for both genders reflecting demand survey results. 3) Conducted consumers' preference survey for design drafts. 4) Made the sample product, and then conducted an evaluation of wearing the actual product. Overall, the wearing test results showed high satisfaction for both genders.

• Reproductive and Developmental Biology
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• 제34권3호
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• pp.143-151
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• 2010

Pluripotency of human embryonic stem cell (hESC) is one of the most valuable ability of hESCs for applying cell therapy field, but also showing side effect, for example teratoma formation. When transplant multipotent stem cell, such as mesnchymal stem cell (MSC) which retains similar differentiation ability, they do not form teratoma in vivo, but there exist limitation of cellular source supply. Accordingly, differentiation of hESC into MSC will be promising cellular source with strong points of both hESC and MSC line. In this study, we described the derivation of MSC like cell population from feeder free cultured hESC (hESC-MSC) using direct differentiation system. Cells population, hESC-MSC and bone marrow derived MSC (BM-MSC) retained similar characteristics in vitro, such as morphology, MSC specific marker expression and differentiation capacity. At the point of differentiation of both cell populations, differentiation rate was slower in hESC-MSC than BM-MSC. As these reason, to verify differentially expressed molecular condition of both cell population which bring out different differentiation rate, we compare the molecular condition of hESC-MSC and BM-MSC using 2-D proteomic analysis tool. In the proteomic analysis, we identified 49 differentially expressed proteins in hESC-MSC and BM-MSC, and they involved in different biological process such as positive regulation of molecular function, biological process, cellular metabolic process, nitrogen compound metabolic process, macromolecule metabolic process, metabolic process, molecular function, and positive regulation of molecular function and regulation of ubiquitin protein ligase activity during mitotic cell cycle, cellular response to stress, and RNA localization. As the related function of differentially expressed proteins, we sought to these proteins were key regulators which contribute to their differentiation rate, developmental process and cell proliferation. Our results suggest that the expressions of these proteins between the hESC-MSC and BM-MSC, could give to us further evidence for hESC differentiation into the mesenchymal stem cell is associated with a differentiation factor. As the initial step to understand fundamental difference of hESC-MSC and BM-MSC, we sought to investigate different protein expression profile. And the grafting of hESC differentiation into MSC and their comparative proteomic analysis will be positively contribute to cell therapy without cellular source limitation, also with exact background of their molecular condition.

• Journal of Periodontal and Implant Science
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• 제26권3호
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• pp.735-751
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• 1996

An ultimate goal of periodontal therapy is to stop the disease process and to regenerate a functionally-oriented periodontium destroyed as a result of periodontal disease. The purpose of this study was to observe the effect of grafting granulation tissue obtained from extraction socket on the regeneration of horizontal furcation defect. Six dogs were used in this study. All mandibular first and third premolars were extracted. At 2, 3, and 5 days after extraction, tissues were obtained from extraction socket of 1 mongrel dog and examined by light microscope. Granulation tissue obtained at 5 days after extraction was chosen as the graft material. Five days later, horizontal furcation defects were created surgically at mandibular second and fourth premolars in the right and left side of the 5 beagle dogs. The entrance area of the artificially prepared "key hole" defects were about $3\;4mm^2$. By random selections, 2 exposed furcation defects were grafted with granulation tissue obtained from extraction socket as experimental group and 1 furcation defect was as control. The flaps were replaced to their original position and sutured with 4-0 chromic cat-gut. Three dogs were sacrificed 4 weeks and two dogs 8 weeks after surgery, and the prepared specimens were examined by light microscope. At 4 weeks, furcations were filled with epithelial lining and fibrous connective tissue infiltrated with chronic inflammatory cells. New bone formation was observed in all groups. Only experimental group showed new cementum formation. At 8 weeks, new cementum, functional arrangement of new PDL fiber, root resorption, and some ankylotic union of newly formed alveolar bone and root surface were observed in all groups. Experimental group showed that epithelial downgrowth was inhibited and new bone formation was more active compared to control. The success rate of the furcation defect healing was higher in experimental group than control. These results suggested that grafting of granulation tissue obtained from extraction socket which combined with reconstructive periodontal flap surgery may promote periodontal regeneration of horizontal furcation defect.

• 멤브레인
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• 제31권3호
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• pp.219-227
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• 2021

분자각인막(MIM)은 특정 분자의 결합자리를 갖고 있는 다공성 고분자 막이다. 비용매유도 상분리(NIPS)법을 사용하여 분자각인막의 지지체로 사용될 P(AN-co-MA) 비대칭막을 제조하고, 여기에 표면 각인법을 적용하여 광활성 이니퍼터 도입과 photo-grafting을 통해 라이소자임 분자각인막을 제조하였다. P(AN-co-MA) 비대칭막을 3-chloropropyltrimethoxysilane과 광활성 이니퍼터 dithiocarbamate로 개질하고, acrylamide 단량체, N,N'-methylenebisacrylamide 가교제, 라이소자임 주형분자 혼합액을 UV 조사 환경에서 혼성중합 시켜 MIM을 제조하였다. 제조된 MIM의 FT-IR과 FE-SEM 및 EDS 분석을 실시한 결과 P(AN-co-MA) 막은 비대칭 단면 구조이었고 표면에 이니퍼터 그룹이 잘 결합되어 있어 MIM이 성공적으로 제조되었다. 제조공정의 변수 조절을 통해 라이소자임의 흡착량이 비각인막(NIM)에 비해 13배 큰 값인 2.7 mg/g을 갖는 P(AN-co-MA) 기반 MIM이 제조되었으며, 막여과 실험을 통해 라이소자임에 대한 오발부민의 투과선택도를 측정한 결과 MIM은 라이소자임의 선택적 결합력이 우수하였다.

• 디지털융복합연구
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• 제13권8호
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• pp.331-336
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• 2015

최근 사물인터넷(IoT), 핀테크(Fintech) 기술의 발전과 활용이 늘어나고 있고, 시스템과 서비스의 융합이 떠오르고 있는 가운데 무선결제 시스템과 위치기반서비스 기술이 관심을 받고 있다. 스마트폰의 사용자들이 현재 무선결제를 많이 이용하고 있는 상황을 고려하여 많은 기업들에서 소비자들의 간편한 결재를 위하여 다양한 기술들을 접목하여 시장에 내놓고 있으며, BLE 기술과 위치기반을 바탕으로 한 기술을 활용하여 간편 결제가 이루어질 수 있도록 ZEP과 같은 결제서비스의 새로운 방식으로 적용되어 나타나고 있다. 이러한 결제 서비스에서 보안의 위협이 존재하는 여부를 확인하고 발생할 수 있는 공격기법을 연구하여 그에 대한 빅데이터 플랫폼 기반의 대응방안을 제시하고자 한다.

• 대한치과보철학회지
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• 제34권1호
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• pp.187-200
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• 1996

After loss of tooth, initial healing process is critical to preserve residual alveolar process. This study was conducted to compare the effect of hydroxylapatite particle synthetic graft and guided tissue regeneration procedure on healing of extraction wounds in 5 mongrel dogs. To investigate the maturity of bone and velocity of bone heating, bone-labeled tracers were used. After 16 weeks healing period, dogs were sacrificed. The specimens were treated with Villanueva bone stain. Fluorescence microscopy and polarized microscopy were performed to exam the pattern of bone formation in the extraction socket. The results were following ; 1. Pattern of bone regeneration in the group of hydroxylapatie graft and the group of membrane protection after hydroxylapatite graft was following ; bone regeneration was slow, regenerated bone was immature, and thickness of cortical layer was thin compare to that of untreated control group. 2. Cortical layers in membrane protected group were somewhat thicker but less condense to that of untreated control group. 3. Infiltration of inflammation cells were found in the groups using hydroxylapatite graft and membrane. We concluded that grafting of replamineform hydroxylapatite particles into the extraction socket delayed healing of the wound and disturbed the formation of cortical bone at the roof of extraction socket. The placement of expanded polytetrafluoroethylene membranes on the extraction socket promotes the bone regeneration. But newly formed bone in cortical layer consists of the cortico-cancellous bone in comparison with the cortical bone of the control group.

• 디지털융복합연구
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• 제14권8호
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• pp.407-413
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• 2016

본 연구의 목적은 한국 문화 콘텐츠인 민화의 도상을 통한 상징체계는 근원적인 우리의 조상들의 긍정적이고 개방적이며 유연한 사고방식의 표현이고, 의사소통의 방법이었으며, 이는 현대에서도 새로운 매체와 더불어 전승할 수 있는 소중한 유산임을 논의하고자 함이다. 이를 위한 연구 방법으로 언어학적 분석을 토대로 보편적 소망을 담은 민화 도상중 하나인 모란의 상징 내용에 디지털 매체를 통한 주얼리 디자인 프로세스를 적용하여 현대적 주얼리 디자인을 하였다. 분석을 통한 결과물로서 모란 도상의 보편적 소망인 부귀와 명예의 내용을 담은 Blossom 과 함박웃음을 주제로 현대의 최신 기술들을 접목하여 3D 디지털 도구를 통한 디자인 프로세스 및 변형 과정을 보여 주었으며, 생산 방식에 있어서도 3D 프린팅 방식과 레이져 커팅 방식을 통해 민화의 상징체계에 있어서의 개방성과 유연한 사고를 접목하여 형상화 하였다.

• Composites Research
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• 제35권5호
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• pp.334-339
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• 2022

본 연구에서는 복합재료 제조 공정 과정 중 수지의 유동 저항성을 대변하는 인자인 투수 계수를 예측하는 알고리즘을 개발하였다. 단방향 연속 섬유 복합재료 내부에서 섬유와 수직인 방향 투수 계수의 정확한 예측을 위해 대표 체적 요소의 단면 형상을 고려하였다. 섬유의 유체 유동 저항성을 정량화하기 위한 인지로 섬유 간 간격이 사용되었고, 등가 길이는 섬유 배열에 따른 수지의 유로 변화를 나타내는 인자로 사용되었다. 전기-유압 유사성을 접목하여 투수 계수 예측 알고리즘을 개발하고 그 타당성을 확인하였다. 알고리즘은 Matlab과 Python으로 구성되고, 타당성 검증을 위해 FLUENT를 통해 예측된 투수 계수와 비교하였다. 알고리즘과 수치 해석을 통해 얻은 투수 계수가 거의 일치함을 확인하여 알고리즘을 검증하였으며, 소요 시간은 수치 해석 대비 약 1/450로 감소하였다.

• 감성과학
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• 제12권2호
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• pp.225-232
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• 2009

국가 간 문화의 차이에 의하여 생활습관이나 방식이 많이 다르게 나타난다. 그중에서도 음식은 다른 분야보다 많은 차이를 나타난다. 특히 음식의 종류에 따라 사용되는 음식도구 중 디자인요소가 동일하고 유사한 것이 있거나 다른 요소와 기능을 갖는 경우도 있다. 따라서 각 국가 간의 음식도구를 유니버설하게 사용할 수 있는 도구 디자인 연구가 필요하다. 본 연구의 목적은 음식에 대한 행동분석프로세스를 개발하여 국가 간 음식문화의 차이에서 오는 공통점과 차이점을 찾아내어 공용으로 사용할 수 있는 음식도구의 디자인요소를 창의성의 관점에서 제안하기 위한 연구이다. 본 연구의 연구방법과 내용으로는 첫째, 음식에 대한 소비자행동분석 프로세스의 개발 및 관찰을 통하여 행동분석에 대한 이론적 고찰과 현장에서 일어나고 있는 행동분석을 접목하여 음식행동분석프로세스를 개발하였다. 둘째로, 개발된 프로세스를 이용하여 국가 간 음식의 주문부터 평가까지의 과정을 비교 분석하고 나타난 현상에 대한 문제점 파악 및 이에 대한 결과물을 각 국가별 학생들을 대상으로 음식도구에 대한 디자인 개발을 진행하였다. 셋째, 국가별 개발된 디자인 안을 대상으로 선호도, 요인분석, 상관분석을 통하여 국가별 선호요소와 창의성평가요소의 상관관계를 알아보았다. 본 연구를 통하여 얻어지는 효과는 개발된 프로세스를 이용하여 국가별, 음식별, 행동별, 식당형태별로 비교분석이 가능하도록 하게 하고 얻어진 결과를 이용하여 구체적으로 음식도구 디자인에 이용할 수 있으며 국가 간 동일 아이템을 디자인 교육시간에 진행시켜 대학의 디자인교육의 비교를 통하여 상호간에 협력과 상호보완으로 새로운 아이디어를 공유, 아이디어 전개에 도움이 될 수 있다.

• 대한치과의사협회지
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• 제50권3호
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• pp.126-139
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• 2012

Loss of dentition can lead to not only compromised esthetics and functions of the patient, but also alveolar bone resorption. Bone grafting with prosthetic reconstruction of the gingiva can be selected for the treatment, and it provides many benefits as prosthetic gingival reconstruction does not require a complicated surgical process and is available within a short period of time, with stable clinical results. However, conventional porcelain fused to metal prosthesis has certain limits due to its size, and deformation after several firing procedures. In this clinical report, the author would like to introduce a patient with severe alveolar resorption who was treated with gingiva-shaped zirconia/titanium CAD/CAM implant fixed prosthesis for esthetic and functional rehabilitation. Clinical reports Clinical report 1, 2 : A case of loss of anterior dentition with atrophied alveolar bone. Implant retained zirconia bridge applied with Procera implant bridge system to simulate the gingiva. Upper structure was fabricated with zirconia all ceramic crown. Clinical report 3, 4 : A case of atrophied maxillary alveolus was reconstructed with fixed implant prosthesis, a CAD/CAM designed titanium structure covered wi th resin on its surface. Anterior dentition was reconstructed with zirconia crown. Conclusion and clinical uses. All patients were satisfied with the outcome, and maintained good oral hygiene. Zirconia/titanium implant fixed prosthesis fabricated by CAD/CAM system was highly accurate and showed adequate histological response. No critical failure was seen on the implant fixture and abutment overall. Sites of severe alveolar bone loss can be rehabilitated by implant fixed prosthesis with CAD/CAM system. This type of prosthesis can offer artificial gingival structure and can give more satisfying esthetics and functions, and as a result the patients were able to accept the outcome more fondly, which makes us less than hard to think that it can be a more convenient treatment for the practitioners.