We present a client-server system architecture for inferring genetic interaction networks based on Bayesian networks. It is typical to take tens of hours when genome-wide large-scale genetic interaction networks are inferred in the form of Bayesian networks. To deal with this situation, batch-style distributed system architectures are preferable to interactive standalone architectures. Thus, we have implemented a loosely coupled client-server system for network inference and user interface. The network inference consists of two stages. Firstly, the proposed method divides a whole gene set into overlapped modules, based on biological annotations and expression data together. Secondly, it infers Bayesian networks for each module, and integrates the learned subnetworks to a global network through common genes across the modules.
The aim of this study is to examine agglomeration patterns of advertising industries and spatial networks of advertisement production in Korea. The focus of analysis is the agglomeration pattern of advertising industries within Seoul because these are agglomerated in Seoul like other business services. Analysis methods are local Moran's I index and location quotient with the regional percentages of each sector's number of employees. Clusters in Gangnam Area are related to start-up advertising firms and global agencies entering domestic advertising markets. Network analysis is used to investigate the spatial networks of TV advertisement production between advertising agencies(AA) and film productions(FP). After transformation of AA-FP network matrix to regional matrix centrality index and brokerage scores are calculated. This analysis shows individual region's different role and position in the AA-FP network. Many agencies in or out of Gangnam Area outsource most advertisement makings to film productions in Gangnam Area. Advertising industry dusters in Gangnam Area is important as of the destination of advertisement production networks and the circulation of those networks.
This paper reviews how electronic media technologies involve and produce time-space dimensions in geometrical spaces, focusing on four theoretical perspectives: van Dijk's dual structure of networks as scale extension and reduction; Latour's actor-networks as fluid and hybrid networks; Virilio's dromospherical time as global media vectors; and Castells' timeless time as non-sequential flows. In these four theoretical perspectives, we can see that electronic media technologies involve different and multiple time-space dimensions in geometrical media spaces: from the two-dimensional spaces (surfaces) of concentric circles, through the one-dimensional spaces (lines) of actor-networks to the zero-dimensional spaces (points) of dromospherical time and finally to the multi-dimensional spaces (hypertexts) of timeless time. The paper concludes by suggesting that we need to explain electronic media spaces not only in terms of geometrical media spaces but also in terms of geographical media spaces in order to understand the ways in which electronic media spaces are dis/embedded in geographical spaces.
The Transactions of the Korean Institute of Electrical Engineers D
/
v.53
no.8
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pp.561-570
/
2004
In this paper, new architectures and comprehensive design methodologies of Genetic Algorithms(GAs) based Genetically optimized Neurofuzzy Networks(GoNFN) are introduced, and a series of numeric experiments are carried out. The proposed GoNFN is based on the rule-based Neurofuzzy Networks(NFN) with the extended structure of the premise and the consequence parts of fuzzy rules being formed within the networks. The premise part of the fuzzy rules are designed by using space partitioning in terms of fuzzy sets defined in individual variables. In the consequence part of the fuzzy rules, three different forms of the regression polynomials such as constant, linear and quadratic are taken into consideration. The structure and parameters of the proposed GoNFN are optimized by GAs. GAs being a global optimization technique determines optimal parameters in a vast search space. But it cannot effectively avoid a large amount of time-consuming iteration because GAs finds optimal parameters by using a given space. To alleviate the problems, the dynamic search-based GAs is introduced to lead to rapidly optimal convergence over a limited region or a boundary condition. In a nutshell, the objective of this study is to develop a general design methodology o GAs-based GoNFN modeling, come up a logic-based structure of such model and propose a comprehensive evolutionary development environment in which the optimization of the model can be efficiently carried out both at the structural as well as parametric level for overall optimization by utilizing the separate or consecutive tuning technology. To evaluate the performance of the proposed GoNFN, the models are experimented with the use of several representative numerical examples.
In an intensively competitive global market, small-and medium-sized firms are puzzled about how to develop sustainable competitive advantages against global rivalries, thus leading satisfactory economic performance. However, despite the roles and contributions of such small-and medium-sized firms in the local community and national economies in Japan, little guidance has been offered to the practical issues related to their strategic behaviors toward global management. To fill this notable knowledge gap, this study aims to investigate the conditions in which how Japanese small-and medium-sized could dominates global market, which is one of key challenges in the literature of small business and entrepreneurship. To obtain better insights to this research area, this study undertakes an in-depth interview survey with I.S.T (Industrial Summit Technology) Corporation that shows off the highest global market share (40 per cent) with seamless polyimide tube product widely used in office automation equipment (e.g., copiers and printers). This method of survey is designed to deeply understand historical considerations about how I.S.T Corporation could dominate in the global market of such seamless polyimide tube product. Based on findings drawn from an interview, this study identifies five major factors enabling I.S.T Corporation to be a competitive global hidden company: vision sharing through founder's entrepreneurship, core competence, strategic network, risk management, and employee engagement. Specifically, to become a global hidden champion, sharing the vision motivating employees to partake in shaping company's future will be the first step on the road to global success through founder's entrepreneurship. However, in order to achieve such a vision, the importance of company's core competence cannot be overemphasized, which differentiates your customer solution with those of competitors. As such, a group of experts will be naturally formed and demonstrates your expertise in the global market, thereby building sustainable competitiveness. On the other hand, to maintain sustainable competitiveness, it is necessary to make up for the weaknesses small-and medium-sized firms suffer from competitive resources while strengthening their own strengths through strategic networks with external organizations. Here, every company has to understand the critical role of risk management, which is essential in this process of being global company so as not to lose your own strengths. Last but not least, do not forget the significant effects of employee engagement in firm performance. To enhance employees' engagement, a company has to create an ideal organization culture which fits into company's history and personality. In doing so, such organization culture can allow the vision and strategy to be implemented into detailed business tactics while facilitating employees to challenge the status quo by experimenting with creative ideas.
Many applications in cluster computing require QoS (Quality of Service) services. Since performance predictability is essential to provide QoS service, underlying systems must provide predictable performance guarantees. One way to ensure such guarantees from network subsystems is to generate global schedules from applications'network requests and to execute the local portion of the schedules at each network interface. To ensure accurate execution of the schedules, it is essential that a global time base must be maintained by local clocks at each network interface. The task of providing a single time base is called a synchronization problem and this paper addresses the problem for system area networks. To solve the synchronization problem, FM-QoS (1) proposed a simple synchronization mechanism called FBS(Feedback-Based Synchronization) which uses built-in How control signals. This paper extends the basic notion of FM-QoS to a theoretical framework and generalizes it: 1) to identify a set of built-in network flow control signals for synchrony and to formalize it as a synchronizing schedule, and 2) to analyze the synchronization precision of FBS in terms of flow control parameters. Based on generalization, two application classes are studied for a single switch network and a multiple switch network. For each class, a synchroniring schedule is proposed and its bounded skew is analyzed. Unlike FM-QoS, the synchronizing schedule is proven to minimize the bounded skew value for a single switch network. To understand the analysis results in practical networks, skew values are obtained with flow control parameters of Myrinet-1280/SAN. We observed that the maximum bounded skew of FBS is 9.2 Usec or less over all our experiments. Based on this result, we came to a conclusion that FBS was a feasible synchronization mechanism in system area networks.
Journal of the Economic Geographical Society of Korea
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v.23
no.4
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pp.373-394
/
2020
The strengthening of multilateral international sanctions against North Korea has raised questions as to how effective they are in exerting pressure on the country's economy. In this paper, we address this question by examining their impact on the country's integration into regional and global apparel production networks. North Korea has in the past decade become an increasingly competitive exporter of apparel on the basis of consignment-based processing arrangements. Official trade data shows a sharp drop in North Korean exports of clothing since the sectoral ban in 2017. There is evidence to suggest, however, that exports have continued on a more informal and clandestine basis. North Korea's integration into apparel production networks has also taken the form of the dispatch of workers to factories in China's northeastern border regions. Yet there is evidence that the recent sanctions imposed on such practices has similarly led to illicit practices such as working on visitors' visas, often with the help of Chinese enterprises and local government. The resilience of North Korea's integration into apparel production networks follows a capitalist logic and is result of the highly profitable nature of apparel production for all actors concerned and a correspondingly strong desire to evade sanctions. As such, the analysis contributes to the literature on sanctions that suggests that the measures may contribute to emergence of growing informal and illicit practices and to the role of the clandestine economy.
The purpose of this study is to investigate the motivating factors determining global logistics network construction and to suggest the most suitable solution for the Korean logistics providers in order to facilitate effectively in global logistics network. The major findings are as follows ; Firstly, 'the factor of network' would be the most essential element for the Korean logistics providers. Secondly, we discovered that among various types of global logistics networks, 'Strategic Alliance' would be the most suitable type for the Korean logistic providers. This study provides the basic information for enhancing global logistics network construction to logistics providers and the Korean government respectively. It also suggests that the implication of Government policy to support global logistics networking business for the Logistics providers should be concentrated on supporting and encouraging M&A among the local logistics partners.
The observations on climate change show a clear increase in the temperature of the Earth's surface and the oceans, a reduction in the land snow cover, and melting of the sea ice and glaciers. The effects of climate change are likely to include more variable weather, heat waves, increased mean temperature, rains, flooding and droughts. The threat of climate change and global warming on human and animal health is now recognized as a global issue. This presentation is described an overview of the latest scientific knowledge on the impact of climate change on zoonotic diseases. Climate strongly affects agriculture and livestock production and influences animal diseases, vectors and pathogens, and their habitat. Global warming are likely to change the temporal and geographical distribution of infectious diseases, including those that are vector-borne such as West Nile fever, Rift Valley fever, Japanese encephalitis, bluetongue, malaria and visceral leishmaniasis, and other diarrheal diseases. The distribution and prevalence of vector-borne diseases may be the most significant effect of climate change. The impact of climate change on the emergence and re-emergence of animal diseases has been confirmed by a majority of countries. Emerging zoonotic diseases are increasingly recognized as a global and regional issue with potential serious human health and economic impacts and their current upward trends are likely to continue. Coordinated international responses are therefore essential across veterinary and human health sectors, regions and countries to control and prevent emerging zoonoses. A new early warning and alert systems is developing and introducing for enhancing surveillance and response to zoonotic diseases. And international networks that include public health, research, medical and veterinary laboratories working with zoonotic pathogens should be established and strengthened. Facing this challenging future, the long-term strategies for zoonotic diseases that may be affected by climate change is need for better prevention and control measures in susceptible livestock, wildlife and vectors in Korea. In conclusion, strengthening global, regional and national early warning systems is extremely important, as are coordinated research programmes and subsequent prevention and control measures, and need for the global surveillance network essential for early detection of zoonotic diseases.
Proceedings of the Korean Vacuum Society Conference
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2011.08a
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pp.312-312
/
2011
In SiH4/H2 discharge for growth process of hydrogenated amorphous silicon (a-Si:H), silane polymers, produced by SiH2 + Sin-1H2n ${\rightarrow}$ SinH2n+2, have no reactivity on the film-growing surface. However, under the SiH2 rich condition, high silane reactive species (HSRS) can be produced by electron collision to silane polymers. HSRS, having relatively strong reactivity on the surface, can react with dangling bond and form Si-H2 networks which have a close correlation with photo-induced degradation of a-Si:H thin film solar cell [1]. To find contributions of suggested several external plasma conditions (pressure, frequency and ratio of mixture gas) [2,3] to suppressing productions of HSRS, some plasma characteristics are studied by numerical methods. For this study, a zero-dimensional global model for SiH4/H2 discharge and a one-dimensional particle-in-cell Monte-Carlo-collision model (PIC-MCC) for pure SiH4 discharge have been developed. Densities of important reactive species of SiH4/H2 discharge are observed by means of the global model, dealing 30 species and 136 reactions, and electron energy probability functions (EEPFs) of pure SiH4 discharge are obtained from the PIC-MCC model, containing 5 charged species and 15 reactions. Using global model, SiH2/SiH3 values were calculated when pressure and driving frequency vary from 0.1 Torr to 10 Torr, from 13.56 MHz to 60 MHz respectively and when the portion of hydrogen changes. Due to the limitation of global model, frequency effects can be explained by PIC-MCC model. Through PIC-MCC model for pure SiH4, EEPFs are obtained in the specific range responsible for forming SiH2 and SiH3: from 8.75 eV to 9.47 eV [4]. Through densities of reactive species and EEPFs, polymerization reactions and production of HSRS are discussed.
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