• 약학회지
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• 제45권1호
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• pp.93-100
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• 2001

Drug inetraction between of enalapril-induced angiotensin converting enzym) inhibitory effect and Ginkgo biloba Ext.-induced antioxidant action was evaluated in spontaneously hypertensive rats. Combination treatment of enalapril (20 mg/kg/day p.o.) and Ginkgo biloba Ext. (60 mg/kg/day, p.o.) for 6 weeks in drinking water to SHRs resulted the inhibition of ACE activity in lung tissue, angiotensin I-induced pressure response and plasma angiotensin II concentration as similar to enalapril alone treatment. But these effects were sustained after 1 week withdrawal of enalapril and Ginkgo biloba Ext. co-administeration. Also, coadministered group did not increase the concentration of bradykinin in lung tissue, which were different from enalapril alone treated group. Co-administration of enalapril and Ginkgo biloba Ext. inhibited the hemolysis induced by UV B type, even Ginkgo biloba Ext. alone treated group did not. These results suggested that Ginkgo biloba Ext. sustained ACE inhibitory effect and reduced the inhibitory effect of bradykinin inactivation induced by enalapril, meanwhile, enalapril increased the antioxidant effect of Ginkgo biloba Ext.

• 한국식품과학회지
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• 제36권3호
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• pp.410-415
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• 2004

본 연구에서는 열풍건조를 통해 제조된 은행분말을 식품에 적응해 보고자 은행분말의 첨가수준을 달리하여 은행죽과 은행떡을 제조하고, 물리적, 관능적 특성 및 소비자 기호도 검사를 통해 바람직한 은행분말 첨가 수준을 조사하였다. 은행죽의 경우 물리적 특성 검사에서는 은행분말 첨가수준이 높아질수록 녹색도와 점도가 감소되었고, 퍼짐성이 증가되었다. 관능적 특성 중 바람직한 특성인 색의 강도와 은행향미는 은행분말 첨가량이 많아질수록 증가하였다. 소비자 기호도 검사를 한 결과, 4:6의 배합 비율로 섞인 은행죽이 전반적인 기호도와 향미 기호도에서 높은 수치를 나타냈다. 은행떡의 경우 물리적 특성 검사에서 은행분말 첨가수준이 증가할수록 녹색도와 부착성이 감소되었다. 관능적 특성 검사 결과, 은행분말 첨가수준이 높아질수록 색의 강도와 은행향미 및 가루끼는 증가하였고 경도와 덩어리 응집성은 감소하였다. 소비자 기호도 검사를한 결과, 16:84의 배합비율을 지닌 은행떡이 전반적인 기호도에서 가장 높은 경향이 나타났다. 은행의 과다 섭취에 따른 문제 가능성을 고려하면 앞으로 은행의 하루 가능 섭취량에 관한 연구 및 은행 첨가량을 줄이면서 다른 부재료의 첨가를 고려하는 연구가 지속적으로 이루어져야겠다고 본다.

• 한국식생활문화학회지
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• 제29권1호
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• pp.84-90
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• 2014

This study investigated the effects of ginkgo nut powder on the antioxidant activity and quality characteristics of mung bean starch gel. Mung bean starch gels were prepared with different amounts of ginkgo nut powder (0, 1, 3, 5, and 7%). The antioxidant activity of ginkgo nut powder and mung bean starch gel was estimated through measuring DPPH free radical scavenging activity and total phenolic acid content. For analyzing quality characteristics several factors were considered: syneresis, pH, color, texture profile analysis, and sensory evaluations. In the results, syneresis in the treated group was higher than the control group. The pH, b values, total phenolic acid content, and DPPH free radical scavenging activity of mung bean starch gels also significantly increased with increasing ginkgo nut powder. In contrast, the L values and a values of mung bean starch gels significantly decreased with increasing ginkgo nut powder. In the texture profile analysis, the mung bean starch gels with 5% and 7% ginkgo nut powder showed significantly lower degrees of hardness, chewiness, and gumminess. On the other hand, cohesiveness was highest in the mung bean starch gels with 5% and 7% ginkgo nut powder. The consumer acceptability score for the mung bean starch gel prepared with 5% and 7% ginkgo nut powder ranked significantly higher than the other groups in flavor and taste. Overall, these results suggest that ginkgo nut powder is a good ingredient for increasing the consumer acceptability and functionality of mung bean starch gel.

• 대한본초학회지
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• 제20권4호
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• pp.11-16
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• 2005

Objectives : This study was designed to propose the effective herb-processing method of Ginkgo Folium in the Oriental medicine. Methods : The books, papers and patents were used to examine the recent usage of Ginkgo Folium. Results : The toxic ingredients of Ginkgo Folium should be removed. Accordingly, a detoxification process using a nonpolar solvent and a vinegar-roasting process in sequence are desirable to assure its safety. The previously developed standard extract (e.g. EGb 761) could be used as a powdered Oriental medicine as well. Conclusions : Ginkgo Folium could not be used widely to treat the diseases in ancient Oriental medicine, because the toxic ingredients could not be removed by any method until recent year. However, Ginkgo Folium might be used as a herbal medicine that invigorates the blood without any difficulty using herb-processing methods suggested in this paper.

• 약학회지
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• 제35권4호
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• pp.271-276
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• 1991

The extractability and stability of ginkgoflavonolglycosides under presence of several cellulose preparations were investigated. The enzymes used were macerosin, cellulose C and cellulase NC. The content variation of the glycosides was measured with HPLC method, using caffeic acid as an internal standard. The methanol extract of ginkgo leaf, containing the total flavonolglycosides of 4.46%, was used for the content comparison. By extraction with the enzymes, each or mixed, the peak levels of all the glycosides began to decrease after 1 or 2 hours. After 24 hour extraction, most of the glycosides were degraded to minor components. The flavonolglycosides in ginkgo leaf were also hydrolysed simply by the water extraction. After 24 hour extraction with water at $40^{\circ}C$, the peak levels of major glycosides were distinctly decreased. Rutin was hydrolysed by enzyme treatment or by ginkgo leaf itself. As a result, it was concluded that the commercially available cellulases and the ginkgo leaf itself contain the activities of $\beta$-glycosidase and $\alpha$-rhamnosidase. Kaempferol-3-O-(6'"-O-p-coumaroylglucosyl)-rhamnoside and four other ginkgo flavonolglycosides were not hydrolysed under the same condition.tion.

• 한국가구학회지
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• 제11권2호
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• pp.37-43
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• 2000

Ginkgo trees have long been planted in Korea as roadside trees and ornamental trees, but the wood was seldom used except some utilization f3r small artifacts. Soaring prices of imported wood and future uncertainty about long-term supply of foreign woods have stimulated research on value-added utilization of less-utilized domestic wood resources such as Ginkgo wood. The processing properties of Ginkgo wood were investigated to determine its utilization potential in this study, and the results of treatability, drying characteristics, gluability, paintability, bending properties, chemical discoloration characteristics were presented.

• 한국가구학회지
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• 제11권1호
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• pp.75-84
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• 2000

Ginkgo trees have long been planted in Korea as roadside trees and ornamental trees, but the wood was seldom used except some utilization for small artifacts. Soaring prices of imported wood and future uncertainty about long-term supply of foreign woods have stimulated research on value-added utilization of less-utilized domestic wood resources such as Ginkgo wood. The properties of Ginkgo wood were investigated to determine its utilization potential in this study, and the results of anatomical, physical, and mechanical studies were presented with chemical compositions.

• 식물병연구
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• 제9권2호
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• pp.99-103
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• 2003

본 연구는 국내산 은행나무(Ginkgo biloba) 뿌리, 열매껍질, 가지 등 부위별 추출물의 진균류, 일반세균 및 해충에 대한 생물활성을 조사하였다. 연구 결과 푸른곰팡이 병균(T.harzianum) 및 대장균(E.coli) 등에 대해 200 ug/disc 농도에서 저해활성을 나타냈으며, 줄기부위가 더 높은 항미생물활성을 보였다. 특히 버섯 배양상 표면에 1mg/ml 수준으로 처리할 경우 푸른 곰팡이병의 발생을 상당히 억제시키는 효과를 나타냈다. 한편, 은행나무 부위별 추출물을 500 ug/ml으로 공시 해충을 처리하였을 경우 대부분의 추출물이 살충활성을 보이며 벼멸구, 배추좀나방, 두점박이응애에 대해 높은 살충활성을 나타냈으며, 특히, 벼멸구에 대해서 8ug/ml의 낮은 농도에서도 살충활성을 나타냈다. 본 연구결과 국내산 은행나무 추출물이 항미생물 및 살충활성이 확인되었는 바 식물유래 병해충 방제용 천연물 농약으로서의 잠재성을 보여주었다.

• 한국토양비료학회지
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• 제30권4호
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• pp.341-344
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• 1997

제약공정에서 생성되는 폐기은행잎이 유기물자원으로서 활용가능한지를 검토하고자 일반 폐기은행잎과 물추출폐기은행잎을 토양과 혼합처리한 후 삼풍벼를 재배하여 조사한 결과는 다음과 같다. 1. 벼의 생육은 폐기은행잎의 시용으로 억제되었으며, 억제효과는 폐기은행잎의 시용량이 많을수록 뚜렸하였다. 2. 벼의 종실중은 폐기은행잎의 시용으로 감소하였으며, 폐기은행잎의 처리방법은 일반폐기은행잎 보다 물추출폐기은행잎에서 감수정도가 적은 경향이었다. 3. 수확기 식물체중 전질소, $K_2O$, CaO, $SiO_2$ 함량 그리고 수확후 토양중 pH, 유기물, 전질소, 인산, CEC, 치환성 Ca 함량은 폐기은행잎의 시용으로 증대되었다.

• Toxicological Research
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• 제12권1호
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• pp.137-141
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• 1996

A teratological study was performed using New Zealand White rabbits to examine the teratological potential of Ginkgo biloba extract(EGb 761), which is a known strong platelet activating factor antagonist. Ginkgo biloba extract(EGb 761) was administered per intravenously during the organogenesis period (day 6th to 18th of gestation) of rabbits at dose levels of 7.5, 15, and 30 mg/kg/day. All pregnant females were sacrificed on day 29 of gestation and teratological abnormalities of their fetuses was examined. No statistically significant difference of body weight change between control and treated groups during experimental periods was noted. There was no statistically signifiant difference of numbers of corpus lutes and implantations, fetal death ratio, fetal sex ratio, and placental weight between control and rabbits exposed to three different concentration ranges of Ginkgo biloba extract (EGb 761). No marked external, visceral and skeletal abnormalities related to Ginkgo biloba extract(EGb 761) were observed in the fetuses. In conclusion Ginkgo biloba extract(EGb 761) does not show any effect on implantation or embryonic development.