• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 춘계학술대회 논문집
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• pp.1156-1162
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• 2007

This paper describes overall background and current status of the establishment of multi axial fatigue testing system for rail fastening component/system. With above viewpoint, general features of rail fastening system, domestic/international testing standards, main features of testing system, application plan, etc. are summarized.

• 소음진동
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• 제3권1호
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• pp.77-82
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• 1993

In general, the dynamic analysis with FEM(Finite Element Method) of large structures requires large computer memory space and long computational time. For the purpose of economical dynamic analysis of large structures, most of engineers want to use an efficient solution algorithm. This paper reports the modified CMS(Component Mode Synthesis) method which uses more efficient algorithm than the classical CMS method. In this paper, it is shown that Ritz vector sets can play the role of normal mode vector sets of substurctures in the CMS algorithm. The modified CMS method has good convergence performance compared with that of the classical CMS method.

• 대한안전경영과학회지
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• 제3권2호
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• pp.123-131
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• 2001

Reliability calculation of a system is frequently required in industrial, military, and everyday life situations. For such a calculation, it is necessary to specify the configuration of components and subsystems, the failure mode of each component, and the states in which the system is classified as failed. In this paper, we are primary interested in the time to the first failure of a system. And we discuss failure probability of coherent system under various condition, especially focus on probability calculation of subsystem failure before system failure used by Bayes formula. Problem statement and general applications illustrated by several examples.

• 한국멀티미디어학회논문지
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• 제7권7호
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• pp.1009-1016
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• 2004

시대의 환경적 변화에 따른 소프트웨어 개발의 발달은 빠른 개발과 높은 생산성을 향상시키기 위한 소프트웨어의 재사용 기술의 확산으로 컴포넌트 기반 개발 방법론이 널리 사용되기 시작했다. 이러한 컴포넌트 기반 개발에서 재사용 가능한 독립적인 컴포넌트의 식별은 컴포넌트 기반 시스템 구축을 위하여 가장 중요한 작업이다. 컴포넌트 식별 방법을 제시하고 있는 기존 방법론들에서는 비즈니스 컴포넌트를 식별함에 있어서 개발자의 경험적 토대를 기반으로 독립적인 컴포넌트를 식별하도록 제시하고 있으므로 평이한 개발자에 의한 비즈니스 컴포넌트 식별이 쉽지 않은 문제점을 가지고 있다. 따라서 본 논문에서는 시스템 컴포넌트를 먼저 식별한 후 비즈니스 컴포넌트를 식별하고 비즈니스 컴포넌트를 식별하기 위하여 분석 클래스 간의 메소드 호출 유형과 메소드 호출 방향에 의한 클래스 간의 종속적 특성과 의존의 강도를 부여하여 효율적으로 컴포넌트를 식별할 수 있는 기준과 방법을 제안한다. 또한 사례 연구를 통하여 시스템 컴포넌트를 중심으로 비즈니스 컴포넌트가 효율적으로 식별됨을 검증한다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.127-130
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• 2012

Aim: We conducted a study in China to assess the health-related quality of life (HRQoL) in patients treated on for malignant bone tumors after surgery, and investigate the possible determinants. Methods: The subjects were 120 patients surgically treated by amputation and limb-salvage for bone tumors during the period of June 2008 to June 2010. The Medical Outcomes Study Short Form 36 (SF-36) was employed to measure the HRQoL of all the patients before and after surgery. Results: With regard to the results of the general quality of life tool (SF-36), we observed a significant improvement of all the indexes of HRQoL after 6 months (p<0.05). PF, RP and BP scores showed significant increase between surgery after 6 and 12 months (p<0.05). The means of the HRQoL of bone tumor patients in our study were still much lower than those of general population in every domain, even 12 months after surgery. Logistic regression showed that female patients were found to have lower scores in physical component summary (PCS) than males (OR=0.64, 95% CI=0.35-0.89). Patients older than 15 years had lower scores in mental component summary (MCS) (OR=0.60, 95% CI=0.32-0.86). Ablative surgery was related to both lower MCS and PCS scores (For MCS, OR=0.54, 95% CI=0.31-0.83; for PCS, OR=0.43, 95% CI=0.25-0.73). Conclusion: Our study showed the treatment for bone tumor could greatly alter the HRQoL of patients. Age, sex and type of surgery were associated with physical or mental HRQoL after surgery.

• 약학회지
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• 제47권2호
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• pp.104-109
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• 2003

The present paper reviews the notion and comparison of the Korea Food and Drug Administration(KFDA) general pharmacology and the International Conference on Harmonisation (ICH) safety pharmacology. General pharmacology or safety pharmacology is termed the study to determine the potential of a compound to induce adverse pharmacological effects. KFDA general pharmacology studies have been considered an important component in drug safety assessment and these were originally referred to those designed to examine effects other than the primary therapeutics effect of a drug candidate. The KFDA notified the Guideline for General Pharmacology in 1997. Safety pharmacology studies were focused on identifying adverse effects on physiological functions. In the ICH came into place S7A Safety Pharmacology Studies for Human Pharmaceuticals in 2001. A new chemical entity should be assessed for its side effects, initially in those physiological systems which are generally agreed to be the key systems that are essential for life; these "core system" include the central nervous system, cardiovascular system and respiratory system in safety pharmacology studies. These studies should be performed in compliance with Good Laboratory Practice (GLP).

• Journal of Chest Surgery
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• 제54권5호
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• pp.412-415
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• 2021

Primary intrapulmonary thymomas (PITs) are defined as thymomas arising in intrapulmonary locations, without an associated mediastinal component. They are rare lesions, the diagnosis of which can be very difficult. We present a case of PIT in an asymptomatic 74-year-old woman in whom pulmonary nodules were found on pulmonary angiography performed for an episode of pulmonary embolism. She underwent wedge resection and the pathology report revealed a PIT. We also summarize this patient's clinicopathological features and discuss the diagnosis, pathogenesis, and treatment of PIT.

• 한국잠사곤충학회지
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• 제32권1호
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• pp.17-30
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• 1990

주성분분석에 의하여 분류된 148개 보존잠품종중에서 제일주성분 score에 따라 10개의 교배모품종을 선발한 후 (정등, 1989), 이들로부터 Top-교잡에 의해 24개 교배조합을 작성하고 조합능력검정을 행함과 동시에 주성분과 교배조합능력과의 상호관계를 분석하였다. 1. 선발된 육종모품종중에서 일본종계 N$_{39}$ 및 중국종계 $C_{46}$ 이 대부분의 형질에서 일반조합능력이 높았다. 2. 특정조합능력은 형질 또는 교배조합에 따라 차이가 심하였다. 3. 육종모품종의 제1주성분 score는 5영경과일수, 전령경과일수, 수견량, 전견중, 견층중, 견층비율, 견사장, 견사량, 해서사장, 생사량비율, 소절등의 일반조합능력과 고도의 정의 상관관계가 있었다. 4. 유사도거리(D$^2$)는 수견양, 해서사장, 해서사량, 해서율, 생사량비율, 소절등의 특정조합능력과 정의 상관이 있었다. 따라서 교배조합의 양친이 원연일수록 이들 5개형질에 대한 특정조합능력은 높게 나타났다. 5. 육종모품종의 특성을 이용한 주성분분석의 제1주성분 score에 의해 일반조합능력의 예측이 가능하였다.

• Journal of the Korean Statistical Society
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• 제20권1호
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• pp.67-76
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• 1991

The empirical Bayes version involves ″independent″ repetitions(a sequence) of the component decision problem. With the varying sample size possible, these are not identical components. However, we impose the usual assumption that the parameters sequence $\theta$=($\theta$$_1$, $\theta$$_2$, …) consists of independent G-distributed parameters where G is unknown. We assume that G $\in$ g, a known family of distributions. The sample size $N_i$ and the decisin rule $d_i$ for component i of the sequence are determined in an evolutionary way. The sample size $N_1$ and the decision rule $d_1$$\in$ $D_{N1}$ used in the first component are fixed and chosen in advance. The sample size $N_2$and the decision rule $d_2$ are functions of *see full text($\underline{X}^1$equation omitted), the observations in the first component. In general, $N_i$ is an integer-valued function of *see full text(equation omitted) and, given $N_i$, $d_i$ is a $D_{Ni}$/-valued function of *see full text(equation omitted). The action chosen in the i-th component is *(equation omitted) which hides the display of dependence on *(equation omitted). We construct an empirical Bayes decision rule for estimating normal mean and show that it is asymptotically optimal.

• Journal of Community Nutrition
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• 제8권1호
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• pp.3-8
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• 2006

This retrospective study was designed to evaluate the nutrient contributions of the five meal components of school lunch menus planned for elementary students in two school districts (District A and B) in the Midwestern state of the United States. The 4-week cycle menu was planned for two time periods (Period 1 and Period 2) following guidelines for NuMenus and general menu planning principles. Menu components of planned and served menus for two time periods were analyzed using $Nutri-Kids^{TM}$. No significant differences in the nutrient content of between Periods 1 and 2 were found for District A. District B served significantly more vitamin A and total fat in Period 1 and significantly more calories, iron, vitamin A, protein, and total fat in Period 2 than was planned. The major nutrients provided by the entree component included protein, calories, cholesterol, total fat, saturated fat, and sodium. Milk was an important source of calcium and provided approximately one-third of the total protein and vitamin A in the meal. The vegetable/fruit component was the major source of vitamins A and C. The grain/bread component provided approximately 20% of the carbohydrates among five meal components. The miscellaneous component affected the sodium and fat content of the menus. Menu planners can use the results of this study to enhance their knowledge of the nutrient contributions of each meal component and as inputs for planning menus that meet children's nutritional requirements.