• Title/Summary/Keyword: gastritis

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Case-Control Study on Effects of Alcohol Intake and Smoking to Gastritis of Korean Adult Men (한국 성인남자에 있어서 흡연 및 음주가 위염에 미치는 영향에 대한 환자-대조군 연구)

  • Hong, Yun-Chul;Park, Chung-Yill;Lee, Won-Chul;Lee, Kang-Sook
    • Journal of Preventive Medicine and Public Health
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    • v.25 no.3 s.39
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    • pp.238-246
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    • 1992
  • We performed case-control studies for the 1,138 Korean adult men. According to the results of UGIS, we classified the gastritis into the erosive gastritis, superficial gastritis, and hypertrophic gastritis. And then, we selected controls among non-gastritis group after matching. Alcohol intake and smoking history was obtained by questionnaire. And we observed the effects of alcohol intake and smoking to the each gastritis. The results obtained were as follows : 1. Smokers had a risk of getting erosive gastritis more than twice(2.6) than non-smokers and there was dose-response relationships between smoking and erosive gastritis. Alcohol intake, however, had no significant relation with the erosive gastritis. 2. Both smoking and alcohol intake had no significant relations with superficial gastritis. 3. Smoking had no significant relation with hypertrophic gastritis, but dividing between those who drank more than 100gm of alcohol a week and those who drank less, we obtained the odds ratio of 3.4 suggesting that there existed a significant relation between moderate or excessive alcohol intake and hypertrophic gastritis. 4. Among the gastritis patients, those who had erosive gastritis smoked most heavily, and those who had hypertrophic gastritis drank most excessively.

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A Case study on the improvement in atrophic gastritis patient using Ortho-Cellular Nutrition Therapy (OCNT) (세포교정영양요법(OCNT)을 이용한 위축성 위염 환자 개선 사례 연구)

  • KangHwa Lee
    • CELLMED
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    • v.13 no.16
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    • pp.60.1-60.3
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    • 2023
  • Objective: Case report on the improvement of atrophic gastritis through application of Ortho-Cellular Nutrition Therapy (OCNT) Method: OCNT was applied to a Korean female in her 40s suffering from severe atrophic gastritis. Results: Atrophic gastritis was improved following the implementation of OCNT. Conclusion: Application of OCNT can be helpful in alleviation of symptoms in patients displaying atrophic gastritis symptoms.

A Case Report on Gastritis Accompanied by Atypical Regenerative Cells Using Ortho-Cellular Nutrition Therapy (OCNT) (세포교정영양요법(OCNT)을 이용한 비정형 재생세포를 동반한 위염 사례)

  • Yeon Choi
    • CELLMED
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    • v.14 no.1
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    • pp.65.1-65.3
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    • 2024
  • Objective: Report on the improvement of gastritis accompanied by atypical regenerative cells through Ortho-Cellular Nutrition Therapy. Methods: A Korean male in his 50s suffering from gastritis accompanied by atypical regenerative cells. Results: Improvement observed in gastritis accompanied by atypical regenerative cells after the implementation of the nutrition therapy. Conclusion: Nutrition therapy can be beneficial in alleviating symptoms of gastritis accompanied by atypical regenerative cells.

Study on Syndrome Differentiation of Gastritis by Korean Standard Classification of Dsease and Cause of Death (한국표준질병 사인분류에 따른 위염(胃炎)의 한의학적 변증 연구)

  • Park, Mi Sun;Kim, Yeong Mok
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.31 no.5
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    • pp.255-263
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    • 2017
  • This article is for understanding relations between the classifications of gastritis and syndrome differentiation types of Korean Medicine through research on syndrome differentiations of clinically applied gastritis and literature of Korean Medicine. Clinical papers were searched in China Academic Journals(CAJ) of China National Knowledge Infrastructure(CNKI) from 1995 to 2015. Conclusions are as follows. First, disease mechanism of chronic gastritis are qi stagnation, damp stagnation, heat obstruction, blood stasis obstruction, yin damage, damage to collaterals with healthy qi deficiency and pathogenic qi. And qi movement stagnation is shown through the status of chronic gastritis. Second, chronic superficial gastritis belongs to qi aspect syndrome and mainly pathogen excess syndrome. And the key mechanisms are congestion and disharmony of stomach qi sometimes combined with liver depression, food accumulation and dampness-heat. Third, chronic atrophic gastritis belongs to qi-blood syndrome and deficiency-excess complex syndrome with the root of spleen qi deficiency and stomach yin deficiency and the tip of blood stasis, qi stagnation. And key mechanism is damage to collaterals with healthy qi deficiency and toxin-blood stasis. Forth, pathogen excess syndromes are shown at the early stage of chronic gastritis and healthy qi deficiency syndromes after the middle stage. Qi deficiency is shown at the beginning of the disease and yin deficiency at the late stage. And qi deficiency is related with superficial gastritis and yin deficiency with atrophic gastritis.

Relevance Epistasis Network of Gastritis for Intra-chromosomes in the Korea Associated Resource (KARE) Cohort Study

  • Jeong, Hyun-hwan;Sohn, Kyung-Ah
    • Genomics & Informatics
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    • v.12 no.4
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    • pp.216-224
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    • 2014
  • Gastritis is a common but a serious disease with a potential risk of developing carcinoma. Helicobacter pylori infection is reported as the most common cause of gastritis, but other genetic and genomic factors exist, especially single-nucleotide polymorphisms (SNPs). Association studies between SNPs and gastritis disease are important, but results on epistatic interactions from multiple SNPs are rarely found in previous genome-wide association (GWA) studies. In this study, we performed computational GWA case-control studies for gastritis in Korea Associated Resource (KARE) data. By transforming the resulting SNP epistasis network into a gene-gene epistasis network, we also identified potential gene-gene interaction factors that affect the susceptibility to gastritis.

Case Study of an Atrophic Gastritis Patient Using Ortho-Cellular Nutrition Therapy (OCNT) (세포교정영양요법(OCNT)을 이용한 장상피화생 환자 사례 연구)

  • Neung-su Cheon
    • CELLMED
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    • v.13 no.7
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    • pp.27.1-27.4
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    • 2023
  • Objective: To report a case of improvement in atrophic gastritis using cell correction nutritional therapy. Methods: A 67-year-old Korean female with impaired digestive function and symptoms of abdominal bloating and hypochlorhydria. Results: Following the application of nutritional therapy, the severity of symptoms was alleviated, ultimately resulting in a complete resolution of atrophic gastritis. Conclusion: Nutritional therapy may be beneficial in alleviating symptoms and aiding in the treatment of patients presenting with atrophic gastritis symptoms.

Acute gastritis associated with Epstein-Barr virus infection in a child

  • Kim, Ji Mok;Song, Chun Woo;Song, Kyu Sang;Kim, Jae Young
    • Clinical and Experimental Pediatrics
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    • v.59 no.sup1
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    • pp.68-71
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    • 2016
  • Infectious mononucleosis is Epstein-Barr virus (EBV) inducing a self-limiting clinical syndrome characterized by fever, sore throat, hepatosplenomegaly, and generalized lymphadenopathy. Gastrointestinal symptoms of EBV infection are nonspecific and occur rarely. EBV inducing acute gastrointestinal pathology is poorly recognized without suspicion. Careful consideration is needed to diagnose gastric involvement of EBV infection including gastric lymphoma, gastric cancer, and gastritis. A few recent cases of gastritis associated with EBV infection have been reported in adolescents and adults. However, there is no report of EBV-associated gastritis in early childhood. We experienced a rare case of 4-year-old girl with EBV gastritis confirmed by in situ hybridization.

The Inhibitory effect of omeprazole-cholestyramine resin in gastric secretion of rat (Omeprazole-cholestyramine resin 제제의 위산분비에 대한 억제효과)

  • 이영욱;김일웅;정지훈;라현오;최경범;이남인;손의동;허인회
    • Biomolecules & Therapeutics
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    • v.8 no.4
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    • pp.318-324
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    • 2000
  • We have examined inhibitory erects on gasritis using omeprazole-cholestyramine resinate, which has been developed to increase the stability of omeprazole, the well-known proton pump inhibitor, in an acidic condition. To test the pharmacological action of this, we investigated the effect of omeprazole-cholestyramine resinate on indomethacin-induced gastritis in rats. Omeprazole was used as a reference drug. Orally administered omeprazole-cholestyramine resinate inhibited the indomethacin-induced gastritis in a dose-dependent manner. The inhibitory effect of omeprazole-cholestyramine resinate on the gastritis was similar to that of reference drug. In addition, rectal adminstration of the omeprazole-cholestyramine resinate inhibited the indomethacin-induced gastritis in a dose-dependent manner. The inhibitory effect of omeprazole-cholestyramine resinate was equipotent to reference drug. The basal gastric acid secretion was decreased when it was administered either orally or rectally. This inhibition of omfprazole-cholestyramine resinate was similar to that of omeprazole. These data suggest that omeprazole-cholestyramine resinate inhibit the gastritis in rats, and are comparable to omeprazole available in market.

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Association of Cytokine Gene Polymorphisms with Gastritis in a Kazakh Population

  • Kulmambetova, Gulmira Nigmetzhanovna;Imanbekova, Meruert Kuatbekovna;Logvinenko, Andrey Alexeevich;Sukashev, Adilbek Temirzhanovich;Filipenko, Maxim Leonidovich;Ramanсulov, Erlan Mirhaidarovich
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.18
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    • pp.7763-7768
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    • 2014
  • Background: Gastritis and gastric cancer are the most common diseases in the Kazakh population. Polymorphisms in genes coding of cytokines have been played important role with gastric disease risk. The risk alleles of cytokines in patients with gastritis can predict the risk of developing gastric cancer. The aim of this study was to investigate cytokine gene polymorphisms as risk factors for the development of gastritis in a case-control study with gastritis patients and healthy individuals from the Kazakh ethnic group, living in North Kazakhstan. Materials and Methods: The polymerase chain reaction followed by direct sequencing were used for detection of two functional polymorphisms in the IL1 gene family, and TaqMan SNP Genotyping Assay Sets were applied for three potentially functional polymorphisms in the IL10 gene, and one in the TNFA promoter. Results: Association analysis of studied allelic variants and the development of gastritis in H. pylori-positive patients showed that IL1B -31C/C, IL1B -511T/T and IL1RN -2/2 allelic variants were associated with development of gastritis (OR=1.8 (1.07-3.16), p=0.025; OR=1.7 (1.04-2.99), p=0.035, and OR=4.92 (2.45-9.85), p<0.001) respectively. Haplotype C-Т that combines both homozygous allelic variants of IL1B gene also had a statistically significant association with slightly higher OR (OR: 1.43, 95% CI: 1.08-1.88). Conclusions: The data from the current study showed that the genotype IL-1B -511Т/-31C-IL1-RN-2 and H. pylori infection increase risk of gastritis in the Kazakh population. That genotype combination might be a factor increasing the risk of developing gastric cancer.

Effect of Artemisiae Argyi Folium Extract on Alcohol-Induced Gastritis (애엽(艾葉) 추출물이 알코올성 위염에 미치는 효과)

  • Lee, Jin A;Seo, Jeong Bok;Kim, Jin Young;Shin, Mi-Rae;Park, Hae-Jin;Roh, Seong-Soo
    • The Journal of Internal Korean Medicine
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    • v.43 no.4
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    • pp.738-750
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    • 2022
  • Objective: Alcohol is known to cause inflammation in the stomach by decreasing the protective substances of the gastric mucosa and increasing oxidative stress. The purpose of this study was to investigate the anti-inflammatory effect of Artemisiae Argyi Folium extract (AF) on alcohol-induced gastritis. Methods: The total polyphenol and flavonoid contents of AF were confirmed through an in vitro experiment. Radical scavenging activities were confirmed using DPPH and ABTS assays. In vivo experiments were conducted on mice divided into 5 groups (n=8): a normal group (Nor), an alcohol-induced gastritis group (Con), an alcohol-induced gastritis group administered 10 mg/kg sucralfate (SC), an alcohol-induced gastritis group administered 100 mg/kg AF (AFL), and an alcohol-induced gastritis group administered 200 mg/kg AF(AFH). The serum levels of reactive oxygen species (ROS) were determined, and protein expressions were confirmed in gastric tissues. Results: In alcohol-induced gastritis, AF alleviated damage to the gastric mucosa caused by alcohol. AF also decreased the serum ROS levels. Western blots showed that AF decreased the expression of NADPH oxidase and decreased the expression of the NF-κB pathway associated with inflammation. AF also decreased the expression of adhesion molecules and chemokine proteins, and increased the expression of anti-inflammatory proteins. Conclusions: AF not only reduced oxidative stress in alcohol-induced gastritis, but it also relieved gastric mucosal inflammation by regulating the expression of the NF-κB pathway.