• Title/Summary/Keyword: gas toxicity

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A Study on the Physical and Chemical Characteristics and Hazards Buthanethiol (Buthanethiol의 물리화학적 특성과 유해성 연구)

  • Kim, Hyeon-Yeong
    • Journal of the Korean Institute of Gas
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    • v.17 no.4
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    • pp.9-17
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    • 2013
  • Butanethiol is known as a typical odorant with hydrogen sulfide, methyl mercaptan, methyl sulfide, but on the physical and chemical properties and biological hazard assessment, including inhalation toxicity data are very scarce. Butanethiol as a colorless transparent liquid, and has physic-chemical characteristics with flash point as $-23^{\circ}C$ and strong fire risk, boiling point $84-85^{\circ}C$, vapor pressure 80.71 mmHg ($25^{\circ}C$), freezing point $-140.14^{\circ}C$. From whole body exposure with SD rats, the $LC_{50}$ is above 2,500 ppm (9.22mg/L), and then it is classified as the acute toxic chemical (inhalation) category 4 according to the governmental notification No. 2012-14.

Microenvironmental Exposures To Volatile Organic Compounds (미규모 환경에서의 휘발성 유기화합물 노출)

  • Jo, Wan-Kuen;Gang, Kwi-Wha;Woo, Hyung-Taek;Park, Jong-Kil
    • Journal of Environmental Science International
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    • v.4 no.5
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    • pp.61-61
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    • 1995
  • Volatile organic compounds(VOCs) are of concern for their potential chronic toxicity, their suspected role in the formation of smog, and their suspected role in destruction of stratospheric ozone. Present study evaluated the exposures to selected VOCs in three microenvironments: 2 chlorinated and 5 aromatic VOCs in the indoor and outdoor air, and 5 aromatic VOCs in the breathing zone air of gas-service station attendants. With permissible Quality Assurance and Quality Control performances VOC concentrations were measured 1) to be higher in indoor air than in outdoor air, 2) to be higher in two Taegu residential areas than in a residential area of Hayang, and 3) to be higher in the nighttime than in the daytime. Among five aromatics, Benzene and Toluene were two most highly measured VOCs in breathing zone air of service station attendants. Based on the sum of VOC concentrations, the VOC exposure during refueling was estimated to be about 10% of indoor and outdoor exposures. For Benzene only, the exposure during refueling was estimated to cause about 52% of indoor and outdoor exposure. The time used to calculate the exposures was 2 minutes for refueling and 24 hours for indoor and outdoor exposures.

Microenvironmental Exposures To Volatile Organic Compounds (미규모 환경에서의 휘발성 유기화합물 노출)

  • 조완근;강귀화
    • Journal of Environmental Science International
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    • v.4 no.5
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    • pp.447-459
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    • 1995
  • Volatile organic compounds(VOCs) are of concern for their potential chronic toxicity, their suspected role in the formation of smog, and their suspected role in destruction of stratospheric ozone. Present study evaluated the exposures to selected VOCs in three microenvironments: 2 chlorinated and 5 aromatic VOCs in the indoor and outdoor air, and 5 aromatic VOCs in the breathing zone air of gas-service station attendants. With permissible Quality Assurance and Quality Control performances VOC concentrations were measured 1) to be higher in indoor air than in outdoor air, 2) to be higher in two Taegu residential areas than in a residential area of Hayang, and 3) to be higher in the nighttime than in the daytime. Among five aromatics, Benzene and Toluene were two most highly measured VOCs in breathing zone air of service station attendants. Based on the sum of VOC concentrations, the VOC exposure during refueling was estimated to be about 10% of indoor and outdoor exposures. For Benzene only, the exposure during refueling was estimated to cause about 52% of indoor and outdoor exposure. The time used to calculate the exposures was 2 minutes for refueling and 24 hours for indoor and outdoor exposures.

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Nutritional Effects on the Environmental Health (영양과 환경과의 관계)

  • 문현경
    • Journal of environmental and Sanitary engineering
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    • v.6 no.2
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    • pp.17-31
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    • 1991
  • The effects of environmental agents on health are great concern for all. It was recognized that each human has differential susceptibility to environmental effects. Susceptibility are changed by many factors includin gdevelopmpntal processes, genetic factors, nutritional stratus, preexisting disease conditions, life style and personal habits. Of all factors nutritional factors seem to be the area most modifiable. Consequently, It is an area that must be more thoroughly evaluated. In this paper, nutrient and environment interactions are reviewed briefly with published literatures. This paper deals with the influence of micronutrients(energy, protein and fat), Vitamins (vitamin 4, vitamin B-complex, vitamin C, vitamin D and vitamin I) and Minerals(calcium, iron, selenium, zinc and other minerls) on environmental effects. The role of arch nutrient was assessed in modifyine the expression of environmental pollutant toxicity with available litertures. In each nutrient section, the effect of environment was considered in following agents : heavy metals(lead, cadmium, mercury, silver and etc), inorganic agents(nitwits, sulfite, fluoride and etc), organic agents(benzene, carbon tatra-chloride, aflatoxin, auto dye, dialbrin etc), Irritant gas(ozone, carbon monooxide and etc), physical agents(X-irradiation, ultra violet, temperature and noise) and insectcides. The extent to which nutritional status modifies environmental effects 3nd its converse, how envirollments affects nutritional status is very complex. In deed, at the present time there are more than 50 chelnical/phycical agents that affect the nutrient metabolism and/or have their toxicity either directly diminished or enhanced by nutrients of those agents, small number of agents for each nutrients have sufficient evidence to warrant any reasonable degree of confidence in their hypothesized associtation. With these information at this present time it is hard to conclude that the recommended dietary allowance for each nutrient should be reconsidered.

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PHARMACOKINETICS OF GINSENG COMPOUNDS

  • Chen Shiow-Edith;Sawchuk Ronald J.;Staba E. John
    • Proceedings of the Ginseng society Conference
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    • 1978.09a
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    • pp.55-66
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    • 1978
  • Five ginsenosides $(A_1,\;A_2,\;B_1,\;B_2,\;C)$ and a yellow pigment were isolated from American ginseng stems and leaves. Ginsenoside $A_2,\;B_1,\;B_2$ and C were proven to be identical with Korean ginseng root ginsenoside $Rg_1,$ Rd, Re and $Rb_2,$ respectively. The yellow pigment proved identical with panasenoside isolated from Korean ginseng leaves. Ginsenoside $A_1$, which was also present in American ginseng roots, was not identical to any of the known root (ginsenoside $R_{0}-Rg_{2}$) and leaf (ginsenoside $F_{1}-F_{3}$) Korean ginseng saponins. A gas-liquid chromatographic method was developed to analyze ginsenosides and sapogenins in rabbit plasma and urine samples. Panasenoside and stigmasterol were found to be the best internal standards for ginsenosides and sapogenihs, respectively. Ginsenoside C had a significantly longer half-life, higher plasma protein binding, lower metabolic and renal clearance than ginsenoside $A_1,\;A_2\;and\;B_2$. Ginsenosides were not found in rabbit plasma and urine samples after oral administration. Ginsenoside C had a higher toxicity than ginsenoside $A_2$ after intraperitoneal administration to mice. Toxicity was not observed after oral administration of the ginsenosides.

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Fate and Toxicity of Spilled Chemicals in Groundwater and Soil Environment II: Flammable (사고 누출 화학물질의 지하수 및 토양 환경 내 거동 및 환경 독성 특성 II: 인화성 물질을 중심으로)

  • Jho, Eun Hea;Shin, Doyun
    • Journal of Soil and Groundwater Environment
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    • v.23 no.6
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    • pp.1-8
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    • 2018
  • In this study, formaldehyde and benzene were selected as the arbitrary chemicals in accidental leakage to environment, and their physicochemical and biological characteristics and toxicity were studied. Also, the fate of these chemicals in soil and groundwater was studied based on the results of previous studies. They can be released into the atmosphere as gas or vapor phase, which then can be photochemically degraded. Since they have relatively high water solubility, they are likely to have high mobility in water and soil. Volatilization of these chemicals from soil is affected by the soil moisture content. Biodegradation of formaldehyde and benzene is one of the important pathways as well. Therefore, it is necessary to study the environmental impacts of leakage accidents of flammable chemicals such as formaldehyde and benzene. Further research on the fate of flammable chemicals in the environment is needed to take appropriate response actions to leakage accidents of flammable chemicals, and this will contribute to the development of practical guidelines to cope with leakage accidents.

Toxicity Evaluation of the Combustion Products from Synthetic Wood as Internal Finish (건축물 내부 마감재인 합성목재별 연소가스 독성평가)

  • Kim, Jong-Buk;Lee, Si-Young
    • Fire Science and Engineering
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    • v.30 no.2
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    • pp.7-18
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    • 2016
  • This study evaluated the toxicity of the burning gas from the synthetic wood products used in housings or warehouses. The combustion products of five materials, viz. impregnated laminated board, MDF, Douglas fir plywood, core plywood, and Lauan retardant, were analyzed using SEM, FTIR and a Cone Calorimeter. For the Lauan retardant, 256,965 ppm of carbon dioxide ($CO_2$) and 1,475 ppm of sulfur dioxide ($SO_2$) were measured, which are 2.5 times and 3.6 times as high as their lethal concentrations of 100,000 ppm and 400 ppm, respectively. For the impregnated laminated board, 1,569 ppm of nitrogen dioxide ($NO_2$) was measured, which is 6 times as high as its lethal concentration of 250 ppm. For MDF, 795 ppm of ammonia ($NH_3$) was measured, which is higher than its lethal concentration of 750 ppm. As a result, most internal-finishes generated toxic combustion products at levels higher than their lethal concentrations, which underlines the importance of the selection and manufacturing of internal-finish materials.

Growth Inhibition of Cucumber by Absorbing Excess Al at Low Soil pH (강한 산성토양에서 Al의 과잉 흡수에 의한 오이 생육장해 양상)

  • Kim, Yoo-Hak;Kim, Myung Sook;Kang, Seong Soo;Lee, Hyeong Yong
    • Korean Journal of Soil Science and Fertilizer
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    • v.45 no.6
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    • pp.925-927
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    • 2012
  • On-site diagnosis applied to soil having a symptom of yellowing and whitening in cucumber leaf and stem. Soil pH determined 4.2 by methods of on-site analysis and 4.5 by soil test analysis. High aluminum in soil solution extracted with water saturation was detected. Leaf and stem tissue were abundant in Al content but not in Ca. Also, N content of leaf and stem was low compared to normal N ranges. This symptom of cucumber assumed to be from the Al and nitrous acid gas toxicity by low soil pH and Eh. Conclusionally, symptom in leaf and stem of cucumber was alleviated and cucumber normally recovered during cultivation period by applying calcium hydroxide solution to correct soil pH up to 6.5. These results showed that low soil pH resulted in aluminum toxicity and N deficiency to plant growth in on-site farming.

Toxicity Evaluation of Effluent Gases from a Residental Fire by Rats (연립 주택 화재시 유독가스 방출 특성과 Rats를 이용한 독성평가)

  • Kim, Hong;Kang, Young-Goo;Kim, Dong-Hyun;Jung, Ki-Chang;Lee, Chang-Seop;Kim, Woon-Hyung
    • Fire Science and Engineering
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    • v.16 no.3
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    • pp.12-15
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    • 2002
  • It has long been recognized that exposure to fire-induced toxic gases is a fatal hazard confront-ing people in fires. In this study, an indoor fire experiment was conducted in an unoccupied residential building located in An-san city, Kyoung-gi province, and the composition of effluent gases, which include CO, $CO_2$, $O_2$, $SO_2$, NO and $NO_2$, were measured by a gas analyzer. A group of lab rats were exposed to the toxic gases released from fire, and the blood samples of the rats were gathered every 2 minutes. A toxicity evaluation was conducted by analyzing the concentrations of Glucose, AST(GOT), ALT(GPT), CBC Count and CO(carboxy)-Hb in the blood samples. Shown from the analysis is the does-response relationship between the CO concentration that rats were exposed to and the CO-Hb concentration in rat blood.

The Experimental Study for the Smoke Optical Density and Toxic Gases of Sandwich Panel Insulations(Single Chamber Method) (샌드위치패널 단열재의 연기농도 및 연소독성가스에 대한 실험적 연구(연소챔버법))

  • Park, Soo-Young;Lee, Woo-Seok;Yeo, Han-Seung;Im, Hong-Soon
    • Fire Science and Engineering
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    • v.20 no.4 s.64
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    • pp.26-32
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    • 2006
  • Nowadays in Korea, KS F 2271 has been using for the test of fire safety performance of sandwich panels. Smoke toxicity test is the test for the toxicity evaluation of smoke and hazardous gas, caused by combustion of building materials and finishing materials. Smoke toxicity can be evaluated by the mean incapacitation time of mice; however this method is not a quantitative way. This test result can be influenced by the health status of mice and test condition. Specific optical density can be quantitatively measured by ISO 5659-2 single chamber method and toxic gases can be quantitatively measured by FTIR analysis. In this study, specific optical density of sandwich panel insulations, which are widely used in Korea, were tested using the ISO 5659-2 single chamber test method and compared with each test. Also, in the second test of three tests for each specimen, FTIR analysis was performed and quantitative test results(HCl, $NO_2$, etc) were compared with each test result.