• Title/Summary/Keyword: gamma-radiation

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Incorporation of phosphate into protein and other nitrogenous compounds in Chlorella cells (Chlorella 세포에서의 $^{32}P$-인산의 단백질 및 다른 질소화합물로의 전환)

  • Lee, Yung-nok
    • Korean Journal of Microbiology
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    • v.5 no.2
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    • pp.61-68
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    • 1967
  • In the process of the incorporation of orthophsphate into protein and other cell constituents, the role of inorganic polyphosphate and RNA-polyphosphate complex and the correlation between them were pursued by analyzing the contents of $^{32}P$ and total P in various fractions of Chlorella cells, which had been uniformly labeled with $^{32}P$ before the inoculation in a normal "cold" medium or P-free medium during the culture. The effects of ionizing radiation and various micronutritional-element deficiencies on the phosphate incorporation into, and biosynthesis of, protein and other introgenus compounds in the cells were also observed. When the uniformly $^{32}P$-labeled algae were grown in a normal "cold" medium the contents of $^{32}$ P in the fractions of protein, DNA and RNA-polyphosphate complex increased, but those in the fraction of acid-insoluble polyphosphate decreased. On the other hand, amount of $^{32}P$in the fraction of RNA was almost unchanged in spite of rapid increase of the total P. In the growing period of $^{32}P$-labeled algae in a P-free medium, amounts of $^{32}P$ in the fractions of DNA, protein and lipid increased, while those in the fractions of RNA-polyphosphate and inorganic polyphosphates decreased. When the algal cells were irradiated with about 70, 000r of gamma-rays before the inoculation in the medium, amounts of phosphate in the fractions of DNA, RNA, nucleotides and protein decreased during the culture, compared with those of the control. However, the phosphate content in the fraction of acid-insoluble polyphosphate of the irradiated cells increased than those of the control. In the growing period of the algae in a Mo-free, medium, amounts of acid-soluble total phosphate and nucleotides of the cells increased, while the amounts of residual protein and RNA decresed compared with those of the normal cells. Amounts of alkali-labile protein and phospholipid of the cells grown in a B-free medium decreased, whereas amount of phosphate in acid-soluble fraction increased compared with the control. In general, the contents of protein and RNA in each microelement deficient cells decreased more or less, compared with those in the normal cells.in the normal cells.

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The Radioprotective Effect of Kuei-Pi-Tang as a prescription of Traditional Chinese Medicine in Mice (생쥐에서 귀비탕 및 구성단미의 방사선 방호효과)

  • Kim, Sung-Ho;Lee, Song-Eun;Oh, Heon;Yang, Jung-Ah;Chung, Chi-Young;Jang, Jong-Sik;Yu, Young-Beob;Jo, Sung-Kee
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.28 no.3
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    • pp.698-704
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    • 1999
  • In this study, we evaluated the radioprotective effects of Kuei Pi Tang and its ingredients, as a prescription of traditional Oriental medicine. The jejunal crypt survival, endogenous spleen colony formation, and apoptosis in jejunal crypt cells were investigated in mice irradiated with high and low dose of ${\gamma}$ rays. In the mice administered with Kuei Pi Tang extract before irradiation, the jejunal crypts were protected significantly(p<0.005) and the frequency of radiation induced apoptosis was reduced(p<0.05). In the experiment on the effects of the ingredients of Kuei Pi Tang, the results indicated that the extract of Dangui(Angelica sinensis), Suanzaoren(Zizyphus valgaris), Rensan (Panax ginseng), Fuling(Poria cocos) and Muxiang(Saussurea lappa) might have a major radioprotective effect. Although the mechanisms of this inhibitory effect remain to be elucidated, these results indi cated that Kuei Pi Tang might be a useful radioprotector, especially since it is a relatively nontoxic natural product.

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비정질 실리콘을 이용한 방사선 계측시 Photoconductive Gain의 특성

  • Lee, Hyeong-Gu;Sin, Gyeong-Seop
    • Journal of Biomedical Engineering Research
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    • v.18 no.3
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    • pp.307-313
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    • 1997
  • he photoconductive gain mechanism in amorphus silicon devices was investigated in connection with applications to radiation detection. Various device types such as p-i-n, n-i-n and i-i-p-i-n structures were fabricated and tested. Photoconductive gain was measured in two time scales : one for short pulses of visible light(<$1{\mu}sec$) which simulate the transit of energetic charged particles or ${\gamma}$-rays, and the other for rather long pulses of light(1msec) which simulate x-ray exposure in medical imaging, We used two definitions of phtoconductive gain : current gain and charge gain which is an integration of the current gain. We obtained typical charge gains of 3~9 for short pulses and a few hundreds for long pulses at a dark current density level of 10mA/$cm^2$. Various gain results are discussed in terms of the device structure, applied bias and dark current density.

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Computational and experimental forensics characterization of weapons-grade plutonium produced in a thermal neutron environment

  • Osborn, Jeremy M.;Glennon, Kevin J.;Kitcher, Evans D.;Burns, Jonathan D.;Folden, Charles M.III;Chirayath, Sunil S.
    • Nuclear Engineering and Technology
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    • v.50 no.6
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    • pp.820-828
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    • 2018
  • The growing nuclear threat has amplified the need for developing diverse and accurate nuclear forensics analysis techniques to strengthen nuclear security measures. The work presented here is part of a research effort focused on developing a methodology for reactor-type discrimination of weapons-grade plutonium. To verify the developed methodology, natural $UO_2$ fuel samples were irradiated in a thermal neutron spectrum at the University of Missouri Research Reactor (MURR) and produced approximately $20{\mu}g$ of weapons-grade plutonium test material. Radiation transport simulations of common thermal reactor types that can produce weapons-grade plutonium were performed, and the results are presented here. These simulations were needed to verify whether the plutonium produced in the natural $UO_2$ fuel samples during the experimental irradiation at MURR was a suitable representative to plutonium produced in common thermal reactor types. Also presented are comparisons of fission product and plutonium concentrations obtained from computational simulations of the experimental irradiation at MURR to the nondestructive and destructive measurements of the irradiated natural $UO_2$ fuel samples. Gamma spectroscopy measurements of radioactive fission products were mostly within 10%, mass spectroscopy measurements of the total plutonium mass were within 4%, and mass spectroscopy measurements of stable fission products were mostly within 5%.

Use of $^{99m}TcO_4^-$ Salivary-Thyroid Ratio As a Test of Thyroid Function (갑상선스캔상에서 갑상선섭취율의 추정방법 : 타액선-갑상선계수율)

  • Yang, Woo-Jin;Chung, Soo-Kyo;Chun, Ki-Sung;Kim, Jong-Woo;Bahk, Yong-Whee
    • The Korean Journal of Nuclear Medicine
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    • v.21 no.2
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    • pp.151-154
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    • 1987
  • Total 114 patients were studied prospectively with radioiodine uptake (RAIU) and $^{99m}TcO_4^-$ thyroid scan to design a very simple, rapid and inexpensive method measuring the thyroid uptake on thyroid scan. After the RAIU was obtained at 24 hours after P.O. of $^{131}I$, Thyroid scan was performed at 20 minutes after LV. of $^{99m}TcO_4^-$ and the bilateral salivary glands were included in the scan field. Pinhole collimated and computer assisted gamma camera was used. Three regions of interest were set on each salivary gland and on the thyroid by automatic edge detection method. Mean counts per pixel were calculated for each ROI and the salivary-thyroid ratio (STR) was defined as; $$STR(%)=\frac{Mean\;counts\;per\;pixel\;of\;salivary\;glands\;(KC)}{Mean\;counts\;per\;pixel\;of\;thyroid\;gland\;(KC)}\times100$$ 114 cases consisted of 41 normal, 55 hyperthyroid and 18 hypothyroid patients and correlation between the STR and the RAID were evaluated in total and each group. The STR and the RAID showed reverse linear regression in 114 cases (r= -0.8, P=0) and closer correlation was shown in hyperthyroid group (r= -0_9, p=0). Mean STR in normal group was 47.6%. In predicting the RAID by STR, sensitivity and specificity were 88.3% and 64.9% in 114 cases and 95.3% and 83.3% in hyperthyroid group. It is recommended that the STR be used in place of the RAID giving same information at saving time, money and radiation exposure.

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Radiation Sensitivity of Some Toxigenic Molds Isolated from Deteriorated Rice (변질미(變質米)에서 분리된 독소생성(毒素生成)곰팡이의 방사선(放射線) 감수성(感受性))

  • Choi, Eon-Ho;Kim, Hong-Lyour;Lee, Su-Rae
    • Korean Journal of Food Science and Technology
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    • v.7 no.3
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    • pp.148-153
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    • 1975
  • Seven toxigenic molds isolated from deteriorated rice in Korea, Aspergillus clavatus, Asp. flavus var. columnaris, Asp. fumigatus, Asp. ochraceus, Penicillium citrinum, Pen. implicatum, and Pen. islandicum, were examined for their sensitivity toward Co-60 gamma rays for survival. Conidia of all tested species showed survival curves of sigmoidal type, from which decimal reduction doses were found to vary in the range of $14{\sim}33$ krad, induction doses, in the range of $12{\sim}56$ krad and inactivation factors at 200 krad, in the range of $4.6{\sim}12.8$, all at a dose rate of 11.56 krad/min. Dose rate effects on the radiosensitivity of Asp. flavus and Pen. islandicum conidia indicated that the higher dose rate (11.56 krad/min) caused decreases in decimal reduction doses as compared with the lower dose rate (2.67 krad/min).

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Development of Sensitivity-Enhanced Detector using Pixelization of Block Scintillator with 3D Laser Engraving (3차원 레이저 각인으로 블록형 섬광체의 픽셀형화를 통한 민감도 향상 검출기 개발)

  • Lee, Seung-Jae;Baek, Cheol-Ha
    • Journal of the Korean Society of Radiology
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    • v.13 no.2
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    • pp.313-318
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    • 2019
  • To improve the sensitivity, a detector using a block scintillator was developed. In the pixelated scintillator, a reflector is located between pixels to move the light generated from the scintillator to the photosensor as much as possible, and sensitivity loss occurs in the reflector portion. In order to improve the sensitivity and to have the characteristics of the pixelated scintillator, the block scintillator was processed into a scintillator in pixel form through three-dimensional laser engraving. The energy spectra and energy resolution of each pixel were measured, and sensitivity analysis of block and pixel scintillator was performed through GATE simulation. The measured global energy resolution was 20.7%, and the sensitivity was 18.5% higher than that of the pixel scintillator. When this detector is applied to imaging devices such as gamma camera and positron emission tomography, it will be possible to shorten the imaging time and reduce the dose of patient by using less radiation source.

Cesium removal in water using magnetic materials ; A review (자성체 물질을 이용한 수중의 세슘제거 동향)

  • Yeo, Wooseok;Cho, Byungrae;Kim, Jong Kyu
    • Journal of the Korean Society of Industry Convergence
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    • v.21 no.6
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    • pp.395-408
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    • 2018
  • Even after the Fukushima nuclear accident in 2011, the rate of production of electric energy using nuclear energy is increasing, but there is a great danger such as the radioactive waste produced when using nuclear power, the catastrophic accident of nuclear power plant, and connection with nuclear weapons. In particular, Cs present in the ionic form of alkaline elements has a long half-life (30.17 years) because it is readily absorbed by the organism and emits intense gamma rays, thus presenting a serious radiation hazard. Therefore, it must be completely removed before it can be released into the natural ecosystem, because it can adversely affect not only humans but also natural ecosystems. Many adsorbents and ion exchangers which have high Cs removal efficiency have been used in recent years to completely separate and remove by self separation in water. Many adsorbents and ion exchangers which have high Cs removal efficiency have been used in recent years to completely separate and remove by self separation in water. In addition, researches have been doing to synthesize magnetic materials with adsorbents such as HCF and PB, and it shows a great effect in the removal rate of Cs present in wastewater or the maximum Cs adsorption amount. In particular, when a magnetic material was applied, excellent results were obtained in which only Cs was selectively removed from other cations. However, new problems such as applicability in the sea where Cs is directly released, applicability in various pH ranges, and failure to preserve the magnetizing force possessed by the magnetic body have been found. However, researches using ferromagnetic field with stronger magnetic properties than those of magnetic bodies is considered to be insufficient. Therefore, it is considered that if the researches combining the ferromagnetic field with the magnetization ability and functional adsorbents more actively, the radioactive material Cs which adversely affects the natural ecosystem can be effectively removed.

Multi-Messenger Observation of Gravitational Wave Source GW170817

  • Im, Myungshin;Kim, Joonho;Choi, Changsu;Lim, Gu;Lee, Chung-Uk;Kim, Seung-Lee;Lee, Mok Hyung;Yoon, Yongmin;Lee, Seong-Kook;Ko, Jongwan;Shim, Hyunjin
    • The Bulletin of The Korean Astronomical Society
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    • v.43 no.2
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    • pp.31.3-31.3
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    • 2018
  • On August 17th 2017, for the first time in the history, the gravitational wave (GW) detectors recorded signals coming from the merger of two neutron stars. This event was named as GW170817, and more interestingly, gamma-ray emission was detected 2 seconds after the gravitational wave signal, and 11 hours later, telescopes in Chile identified that the GW signal came from the NGC 4993 galaxy at the distance of about 40 Mpc. This is again the first time that electromagnetic (EM) signals are detected for a GW source. The follow-up observations by astronomers all around the world, including our group in Korea, successfully identified the optical emission as the kilonova, the elusive optical/NIR counterpart that has been proposed to originate from a neutron star merger. This whole event started the new era of astronomy, so-called the "multi-messenger astronomy", where the combined information from GW and EM radiation reveals an unprecedented view of the universe. In this talk, I summarize this exciting event, and describe the efforts by Korean astronomers that have led to important discoveries about the kilonova and the host galaxy properties, and finally provide the future prospects.

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Evaluation of photon radiation attenuation and buildup factors for energy absorption and exposure in some soils using EPICS2017 library

  • Hila, F.C.;Javier-Hila, A.M.V.;Sayyed, M.I.;Asuncion-Astronomo, A.;Dicen, G.P.;Jecong, J.F.M.;Guillermo, N.R.D.;Amorsolo, A.V. Jr.
    • Nuclear Engineering and Technology
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    • v.53 no.11
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    • pp.3808-3815
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    • 2021
  • In this paper, the EPICS2017 photoatomic database was used to evaluate the photon mass attenuation coefficients and buildup factors of soils collected at different depths in the Philippine islands. The extraction and interpolation of the library was accomplished at the recommended linear-linear scales to obtain the incoherent and total cross section and mass attenuation coefficient. The buildup factors were evaluated using the G-P fitting method in ANSI/ANS-6.4.3. An agreement was achieved between XCOM, MCNP5, and EPICS2017 for the calculated mass attenuation coefficient values. The buildup factors were reported at several penetration depths within the standard energy grid. The highest values of both buildup factor classifications were found in the energy range between 100 and 400 keV where incoherent scattering interaction probabilities are predominant, and least at the region of predominant photoionization events. The buildup factors were examined as a function of different soil silica contents. The soil samples with larger silica concentrations were found to have higher buildup factor values and hence lower shielding characteristics, while conversely, those with the least silica contents have increased shielding characteristics brought by the increased proportions of the abundant heavier oxides.