Eclecticism, fusing and mixing heterogeneous and contrasting elements to create a new awareness of beauty, is based on diversity and pluralism, and as such fits well with the demand of the contemporaries who pursue individualization and diversification, which explains the current vogue for Eclecticism. As a precondition to grasp eclectic styles that are expressed in modern textile design, this study looks into the characteristics of eclecticism in modern art and applies the insight so gained to textile design in an attempt to understand transformations of modern textile design by considering the aesthetic effects and plastic characteristics suggested by the new trend. The result of our research indicates that the trends that characterize modern textile design can be divided into three categories as follows: 1) Mixing of high culture and low culture through cultural fusion, 2) Fusion of differing sensitivities through blending of times, 3) Blending of regional characteristics through geographical mixing. Characteristics of textile designs as influenced by these trends can be summarized as: 1) a conversion in the way textile designs are viewed, 2) increasing emphasis on the playfulness of representation and 3) multi-cultural expressions. In short, eclecticism of textile design represents a phase of modern society that is increasingly oriented toward multifacetedness and points to a direction for a new possibility of future textile designs, necessitating a continuous research along this line.
The topic of 21st century's culture is the appearance of digital media. It made changes as big as the industrial revolution, and our society is now ruled by the digital media. The main objective of this study is to forecast the direction of current visual design education by researching and analyzing how the introduction of digital media is influencing the evolution of visual design's identity, which is an ever changing and developing science. Also, since the rain target of digital media is the young generation, the change in the method of expressing visual language is inevitable In fact, there have been a lot of changes in the methods of creating and distributing visual communication due to the introduction of digital media. In the past, most educational institutions of design had similar objectives, curriculums and teaching methods to provide education that prepares students for practical business. However, in this digital media era, the application and utilization of visual design are uncomparably diversified, and it is generally classified as interaction. The purpose of this study is to find a wat to train visual design professionals in this digital era. For this purpose, this study will identify a new educational system that fulfills the demands of this society by fusing the traditional education and the new digital education, and will suggest what an design education institute that is ahead of the demands of society should be like.
Current influenza vaccines are produced in embryonated chicken eggs. However, egg-based vaccines have various problems. To address these problems, recombinant protein vaccines have been developed as new vaccine candidates. Unfortunately, recombinant proteins frequently encounter aggregation and low stability during their biogenesis. It has been previously demonstrated that recombinantly expressed proteins can be greatly stabilized with high solubility by fusing stabilizing peptide (SP) derived from the C-terminal acidic tail of human synuclein (ATS). To investigate whether SP fusion proteins can induce protective immunity in mice, we produced influenza HA and SP fusion protein using a baculovirus expression system. In in vitro tests, SP-fused recombinant HA1 (SP-rHA1) was shown to be more stable than recombinant HA1 (rHA1). Mice were immunized intramuscularly with baculovirus-expressed rHA1 protein or SP-rHA1 protein ($2{\mu}g/mouse$) formulated with aluminum hydroxide. Antibody responses were determined by ELISA and hemagglutination inhibition assay. We observed that SP-rHA1 immunization elicited HA-specific antibody responses that were comparable to rHA1 immunization. These results indicate that fusion of SP to rHA1 does not negatively affect the immunogenicity of the vaccine candidate. Therefore, it is possible to apply SP fusion technology to develop stable recombinant protein vaccines with high solubility.
Alkali-silica reaction (ASR) in concrete can induce degradation in its mechanical properties, leading to compromised serviceability and even loss in load capacity of concrete structures. Compared to other properties, ASR often affects the modulus of elasticity more significantly. Several empirical models have thus been established to estimate elastic modulus reduction based on the ASR expansion only for condition assessment and capacity evaluation of the distressed structures. However, it has been observed from experimental studies in the literature that for any given level of ASR expansion, there are significant variations on the measured modulus of elasticity. In fact, many other factors, such as cement content, reactive aggregate type, exposure condition, additional alkali and concrete strength, have been commonly known in contribution to changes of concrete elastic modulus due to ASR. In this study, an artificial intelligent model using artificial neural network (ANN) is proposed for the first time to provide an innovative approach for evaluation of the elastic modulus of ASR-affected concrete, which is able to take into account contribution of several influence factors. By intelligently fusing multiple information, the proposed ANN model can provide an accurate estimation of the modulus of elasticity, which shows a significant improvement from empirical based models used in current practice. The results also indicate that expansion due to ASR is not the only factor contributing to the stiffness change, and various factors have to be included during the evaluation.
I would like to design a customized furniture for one-person households that have emerged as mainstream in modern society. In particular, I focused on the tendency of generations to improve the quality of life, and wanted to design the aesthetic furniture close to art furniture. To this end, I look at art furniture in domestic and overseas furniture. and present the concept of combined custom design based on current trends. The combined custom design differs from the existing one by creating separate designs for each part and fusing them to enable more diverse and aggressive molding. This is in harmony with the active tendency of one-person households who shows a lot of interest in the quality of life. Especially, it is suitable for small quantity production of various kinds, so it can be produced in the existing craft workshop system, and the two tables can confirm the possibility of the morphological concept according to actual combined custom design.
Mohl, Britta S.;Chen, Jia;Sathiyamoorthy, Karthik;Jardetzky, Theodore S.;Longnecker, Richard
Molecules and Cells
/
v.39
no.4
/
pp.286-291
/
2016
Epstein-Barr virus (EBV) is the prototypical ${\gamma}$-herpesvirus and an obligate human pathogen that infects mainly epithelial cells and B cells, which can result in malignancies. EBV infects these target cells by fusing with the viral and cellular lipid bilayer membranes using multiple viral factors and host receptor(s) thus exhibiting a unique complexity in its entry machinery. To enter epithelial cells, EBV requires minimally the conserved core fusion machinery comprised of the glycoproteins gH/gL acting as the receptor-binding complex and gB as the fusogen. EBV can enter B cells using gp42, which binds tightly to gH/gL and interacts with host HLA class II, activating fusion. Previously, we published the individual crystal structures of EBV entry factors, such as gH/gL and gp42, the EBV/host receptor complex, gp42/HLA-DR1, and the fusion protein EBV gB in a postfusion conformation, which allowed us to identify structural determinants and regions critical for receptor-binding and membrane fusion. Recently, we reported different low resolution models of the EBV B cell entry triggering complex (gHgL/gp42/HLA class II) in "open" and "closed" states based on negative-stain single particle electron microscopy, which provide further mechanistic insights. This review summarizes the current knowledge of these key players in EBV entry and how their structures impact receptor-binding and the triggering of gB-mediated fusion.
The purpose of this study is to analyze the eco-friendly design characteristics of contemporary children's collections. Photos from FirstviewKorea were utilized for analysis; 29 brands were selected that included children's clothing collections featuring eco-friendly characteristics from 2007 to 2018. The results are as follows. First, naturalness was the most frequent characteristic of environmentally friendly children's collections. It was not conveyed in an eccentric way in any season, showed a relatively uniform distribution, and was seen in various ways, including printed on the fabric and expressed in $appliqu\acute{e}s$ and embroidery. Second, handcrafted features frequently changed according to seasonal trends. Various methods such as beading, embroidery, applique, sewing techniques, and handbags were used, which enhanced manual workability, discrimination from other designs. Third, traditionality is divided into the characteristics of ethnicity and revivalism. National traditions were expressed in the clothing and reflected the current generation while connecting to the past. Fourth, simplicity appeared in classic designs such as simple silhouettes, sparse decoration, natural colors, and comfortable dress length that is not tight on the body. Simplicity was not a frequent feature due to the characteristics of the children's clothing collections. Fifth, playfulness functioned to enhance the children's clothing's wear frequency. Although it was the least frequent of all the characteristics, it seemed to increase the design fun and the clothing's value by fusing with other characteristics such as handcraftedness and naturalness.
The adaptive sparse representation (ASR) can effectively combine the structure information of a sample dictionary and the sparsity of coding coefficients. This algorithm can effectively consider the correlation between training samples and convert between sparse representation-based classifier (SRC) and collaborative representation classification (CRC) under different training samples. Unlike SRC and CRC which use fixed norm constraints, ASR can adaptively adjust the constraints based on the correlation between different training samples, seeking a balance between l1 and l2 norm, greatly strengthening the robustness and adaptability of the classification algorithm. The correlation coefficients (CC) can better identify the pixels with strong correlation. Therefore, this article proposes a hyperspectral image classification method called correlation coefficients and adaptive sparse representation (CCASR), based on ASR and CC. This method is divided into three steps. In the first step, we determine the pixel to be measured and calculate the CC value between the pixel to be tested and various training samples. Then we represent the pixel using ASR and calculate the reconstruction error corresponding to each category. Finally, the target pixels are classified according to the reconstruction error and the CC value. In this article, a new hyperspectral image classification method is proposed by fusing CC and ASR. The method in this paper is verified through two sets of experimental data. In the hyperspectral image (Indian Pines), the overall accuracy of CCASR has reached 0.9596. In the hyperspectral images taken by HIS-300, the classification results show that the classification accuracy of the proposed method achieves 0.9354, which is better than other commonly used methods.
Diagnostic and functional imaging device have been developed independently. The recognition that combining of these two devices can provide better diagnostic outcomes by fusing anatomical and functional images. The representative examples of combining devices would be PET/CT and SPECT/CT. Development and their applications of animal imaging and instrumentation have been very active, as new drug development with advanced imaging device has been increased. The development of advanced imaging device resulted in researching and developing for detector technology and imaging systems. It also contributed to develop a new software, reconstruction algorithm, correction methods for physical factors, image quantitation, computer simulation, kinetic modeling, dosimetry, and correction for motion artifacts. Recently, development of MRI and PET by combining them together was reported. True integration of MRI and PET has been making the progress and their results were reported. The recent status of imaging and instrumentation in nuclear medicine is reported in this paper.
The purpose of this study is to investigate the current conditions of the domestic and foreign curricula in the field of chemical engineering and to draw implications. The results of the study are as follows. Most of the domestic research universities (including non-certified universities) have curricula organized within the scope of the ABEEK certification, which is the minimum standard guide for chemical engineering curricula. However, we are concerned that chemical engineering education in some domestic universities may lack in education quality and program relevance. Graduates from these universities may not have equivalent qualifications as international graduates. It is considered that most of the 12 domestic universities organize their subjects according to the certificate of accreditation standard and to the traditional subjects of chemistry in the 'Department of Chemical Engineering' or 'Department of Chemical and Biological Engineering Chemical and Biological Engineering'. However, due to the increase in the number of overlapping subjects with other majors because of the movement towards academic diversity, the integrity of the chemical engineering curricula is at risk. In addition, after surveying the major and research areas of the department professors, it has been found that there is a shortage of professors who have majored in chemical engineering. Therefore, there is a concern that students may lack understanding of the core principles of chemical engineering. The results of the analysis of the curricula of overseas research universities (including non-certified universities) are as follows. Although the chemical engineering industry in developed countries like the United States and Europe is advancing and changing very quickly, the chemical engineering education in these countries is highly focused on traditional subjects and other related subjects in order to cultivate traditionally trained chemical engineers. The Department of Chemical Engineering at overseas universities still maintains the academic integrity of the chemical engineering field. This is a significant suggestion for our country. On the other hand, domestic universities are changing the name of their chemical engineering major, or even if the name is maintained, they are fusing their curriculum with other majors such as material engineering. Therefore, it is very necessary at this point to start a discussion regarding the integrity of the department of chemical engineering in Korea. We hope that the departments of chemical engineering in domestic universities maintain the integrity of traditional chemical engineering while operating the curriculum within the scope of the standards of the engineering education certification system.
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