Protection of Mice Against Pandemic H1N1 Influenza Virus Challenge After Immunization with Baculovirus-Expressed Stabilizing Peptide Fusion Hemagglutinin Protein |
Yang, Eunji
(Molecular Vaccinology Section, Laboratory Science Division, International Vaccine Institute)
Cho, Yonggeun (Department of Microbiology and Immunology, Yonsei University College of Medicine) Choi, Jung-ah (Molecular Vaccinology Section, Laboratory Science Division, International Vaccine Institute) Choi, YoungJoo (Molecular Vaccinology Section, Laboratory Science Division, International Vaccine Institute) Park, Pil-Gu (Department of Microbiology and Immunology, Yonsei University College of Medicine) Park, Eunsun (Department of Microbiology and Immunology, Yonsei University College of Medicine) Lee, Choong Hwan (ATGen Co. Ltd.) Lee, Hyeja (ATGen Co. Ltd.) Kim, Jongsun (Department of Microbiology and Immunology, Yonsei University College of Medicine) Lee, Jae Myun (Department of Microbiology and Immunology, Yonsei University College of Medicine) Song, Manki (Molecular Vaccinology Section, Laboratory Science Division, International Vaccine Institute) |
1 | Braun A, Kwee L, Labow MA, Alsenz J. 1997. Protein aggregates seem to play a key role among the parameters influencing the antigenicity of interferon alpha (IFN-alpha) in normal and transgenic mice. Pharm. Res. 14: 1472-1478. DOI ScienceOn |
2 | Chua JV, Chen WH. 2010. Bench-to-bedside review: vaccine protection strategies during pandemic flu outbreaks. Crit. Care 14: 218. DOI |
3 | Jeong KJ, Lee SY. 1999. High-level production of human leptin by fed-batch cultivation of recombinant Escherichia coli and its purification. Appl. Environ. Microbiol. 65: 3027-3032. |
4 | Lee EN, Kim YM, Lee HJ, Park SW, Jung HY, Lee JM, et al. 2005. Stabilizing peptide fusion for solving the stability and solubility problems of therapeutic proteins. Pharm. Res. 22: 1735-1746. DOI |
5 | Kim TD, Paik SR, Yang CH. 2002. Structural and functional implications of C-terminal regions of alpha-synuclein. Biochemistry 41: 13782-13790. DOI ScienceOn |
6 | Kim YM, Lee HJ, Lee JE, Kim HY, Kim J. 2009. Expression of human interferon alpha-1 with enhanced stability via the tagging system of a stabilizing peptide. Protein Expr. Purif. 63: 140-146. DOI ScienceOn |
7 | Kumru OS, Joshi SB, Smith DE, Middaugh CR, Prusik T, Volkin DB. 2014. Vaccine instability in the cold chain: mechanisms, analysis and formulation strategies. Biologicals 42: 237-259. DOI ScienceOn |
8 | Palese P. 2004. Influenza: old and new threats. Nat. Med. 10: S82-S87. DOI ScienceOn |
9 | Park SM, Ahn KJ, Jung HY, Park JH, Kim J. 2004. Effects of novel peptides derived from the acidic tail of synuclein (ATS) on the aggregation and stability of fusion proteins. Protein Eng. Des. Sel. 17: 251-260. DOI |
10 | Clayton DF, George JM. 1998. The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease. Trends Neurosci. 21 : 249-254. DOI ScienceOn |
11 | Altmann F, Staudacher E, Wilson IB, Marz L. 1999. Insect cells as hosts for the expression of recombinant glycoproteins. Glycoconj. J. 16: 109-123. DOI ScienceOn |
12 | Treanor JJ, Betts RF, Smith GE, Anderson EL, Hackett CS, Wilkinson BE, et al. 1996. Evaluation of a recombinant hemagglutinin expressed in insect cells as an influenza vaccine in young and elderly adults. J. Infect. Dis. 173: 1467-1470. DOI ScienceOn |
13 | Park SM, Jung HY, Chung KC, Rhim H, Park JH, Kim J. 2002. Stress-induced aggregation profiles of GST-alphasynuclein fusion proteins: role of the C-terminal acidic tail of alpha-synuclein in protein thermosolubility and stability. Biochemistry 41: 4137-4146. DOI ScienceOn |
14 | Park SM, Jung HY, Kim TD, Park JH, Yang CH, Kim J. 2002. Distinct roles of the N-terminal-binding domain and the C-terminal-solubilizing domain of alpha-synuclein, a molecular chaperone. J. Biol. Chem. 277: 28512-28520. DOI ScienceOn |
15 | Petrovsky N. 2006. Novel human polysaccharide adjuvants with dual Th1 and Th2 potentiating activity. Vaccine 24 (Suppl 2): S2-26-S2-29. DOI |
16 | Ratner RE, Phillips TM, Steiner M. 1990. Persistent cutaneous insulin allergy resulting from high-molecularweight insulin aggregates. Diabetes 39: 728-733. DOI |
17 | Reperant LA, Rimmelzwaan GF, Osterhaus AD. 2014. Advances in influenza vaccination. F1000Prime Rep. 6: 47. DOI |
18 | Samant Y, Lanjewar H, Parker D, Block L, Tomar GS, Stein B. 2007. Evaluation of the cold-chain for oral polio vaccine in a rural district of India. Public Health Rep. 122: 112-121. DOI |
19 | Treanor JJ, Schiff GM, Couch RB, Cate TR, Brady RC, Hay CM, et al. 2006. Dose-related safety and immunogenicity of a trivalent baculovirus-expressed influenza-virus hemagglutinin vaccine in elderly adults. J. Infect. Dis. 193: 1223-1228. DOI ScienceOn |
20 | Treanor JJ, Schiff GM, Hayden FG, Brady RC, Hay CM, Meyer AL, et al. 2007. Safety and immunogenicity of a baculovirus-expressed hemagglutinin influenza vaccine: a randomized controlled trial. JAMA 297: 1577-1582. DOI ScienceOn |
21 | Volkin DB, Burke CJ, Sanyal G, Middaugh CR. 1996. Analysis of vaccine stability. Dev. Biol. Stand. 87: 135-142. |
22 | Collin N, de Radigues X. 2009. Vaccine production capacity for seasonal and pandemic (H1N1) 2009 influenza. Vaccine 27: 5184-5186. DOI ScienceOn |
![]() |