• 한국막학회:학술대회논문집
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• 한국막학회 1999년도 Energy Saving Membrane Separtion Systems 에너지 절약형 막분리 시스템
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• pp.39-39
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• 1999

Membrane separation technology has become a more attractive technology on waste water treatment and water recycle in recent years. On this application, membrane does not take main part of treatment, such as decomposition or handling of organic matter in the waste water, but it is very important supporting method in the total system. Activated sludge is most popular method as main part. In the system , membrane works as a separator to obtain clear water after biological treatment, by which the permeate could be released, recycled or applied to further additional treatment, instead of conventional sedimentation, coagulation and sand filtration. We would like to introduce our system cases for waste water treatment and water recycle, in which membrane separation technology works. In most of cases, membranes are applied to solid- liquid separation of activated sludge. Our experiences will be introduced as following items.

• 상하수도학회지
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• 제30권5호
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• pp.597-604
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• 2016

This study was begun with the object of actively reflection the rapid technological advancements of the electronical control and mechanical control industries to sewage disposal methods. Or focuses on applying a flow control method that utilizes inverters and automatic valves to sewage treatment process systems. This study proposes that sewage treatment process systems architects must acquire a certain degree of technical skills in the areas of electrical and mechanical controls in order to raise the standard of completeness of sewage treatment process systems. And further emphasizes that there is required continuous research on automatics valves that are used in sewage treatment.

• 한방재활의학과학회지
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• 제33권3호
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• pp.129-134
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• 2023

Objectives The purpose of this study was to review the studies of catgut embedding related to obesity treatment. Methods We searched the papers with key words of obesity and catgut embedding via searching Research Information Sharing Service, DBpia, Koreanstudies Information Service System, Oriental Medicine Advanced Searching Integrated System, Scopus, PubMed. Additional data including study design, study topics, characteristics of participants and treatment, outcomes was extracted from full text of each study. Results There were nine studies about the catgut embedding related to obesity treatment. Five articles were conducted in China, two articles were conducted in Mexico, and two articles was published in Korea. Analysis of seven experimental studies and two observational studies were conducted to describe each research subject, method, and research results. Conclusions More interest and further research will be needed on catgut embedding related to obesity treatment in the Korean medicine to achieve clinical application and to develop treatment protocols for the obesity disease.

• Applied Microscopy
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• 제43권3호
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• pp.103-109
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• 2013

ICI 182,780 (ICI) is known as an estrogen receptor antagonist, whereas propyl pyrazole triol (PPT) is an estrogen receptor agonist. In this study, ICI or ICI added with PPT was injected into adult male mice. Body and reproductive organ weights were reduced in the ICI added with PPT group compared to the control group. Further, the ICI and ICI added with PPT groups both showed increases in luminal areas of the seminiferous tubules of the testis, whereas cell heights of efferent ductules and the initial segment of the epididymis were reduced. Sperm count in the caudal epididymis was reduced in the ICI and ICI added with PPT groups. These results show that reproductive tissues were more deeply affected in the ICI added with PPT group. We also demonstrated that treatment with ICI resulted in histological changes in the testis, efferent ductule, and epididymis. Further, alternate treatment with ICI and PPT induced abnormalities in reproductive organs. These results indicate that a high concentration of PPT together with ICI may cause histological abnormalities instead of histological restoration in reproductive organs.

• 한국산업융합학회 논문집
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• 제5권3호
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• pp.213-218
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• 2002

Total nitrogen is a major pollutant which mostly causes eutrophication and red tide. Wastewater effluent from printing of cotton-viscose rayon containing high concentrations of total nitrogen can not be effectively treated with a typical biological treatment process. This paper provides a new treatment process and experimental results for the removal of high strength nitrogen from dyeing wastewater. The optimum conditions of air stripping for the removal of total nitrogen include around pH 12, temperature $60^{\circ}C$ with 60 minutes of stripping time. In case of a filtration-air stripping process, an initial level ($500mg/{\ell}$) of total nitrogen was significantly reduced to below $60mg/{\ell}$. Deconite was synthesised for further decomposition of organic nitrogen. Thus, a filtration-decomposition-air stripping process was possibly achieved, by which a high level ($900mg/{\ell}$) of total nitrogen was effectively removed to below $60mg/{\ell}$ P. Finally, a continuous new process for the removal of total nitrogen is proposed and confirmed, based on batch experimental results, and its process validity is further discussed throughout.

• Childhood Kidney Diseases
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• 제25권2호
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• pp.92-111
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• 2021

Purpose: Nephrotic syndrome (NS) is the most common form of glomerulopathy in children. Most pediatric patients respond to glucocorticosteroid treatment (steroid-sensitive NS, SSNS), while approximately 10-15% will remain unresponsive or later become steroid-resistant. There has been a long-standing effort to find biomarkers that may predict steroid responsiveness. Methods: We systematically reviewed current studies which investigated clinically relevant biomarkers for predicting steroid responsiveness in pediatric NS. We performed a PubMed and EMBASE search to identify eligible articles. We collected data on urinary markers, blood/serum markers (including cellular phenotypes and mRNA expression), genotypes and HLA allele frequency. Results: A total of 659 articles were identified following electronic and manual searches. After reviewing the titles, abstracts, and full texts, 72 eligible articles were finally included. Vitamin D-binding protein (VDBP) seemed to be significantly elevated in SRNS than in SSNS, in both serum and urine specimen, although further validation is required. Conclusions: The present paper narratively illustrates current understandings of potential biomarkers that may help predict steroid responsiveness. Further investigation and collaboration involving a larger number of patients are necessary.

• 한방재활의학과학회지
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• 제27권1호
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• pp.67-75
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• 2017

The purpose of this study is to report the effectiveness of diarrhea-inducing treatment by Gamsui-mal for lumbar spinal stenosis. During hospitalization four patients with lumbar spinal stenosis were treated with diarrhea-inducing treatment by Gamsui-mal and acupuncture, herbal medicine, moxibustion, cupping treatment, Bee-venom pharmacopuncture. Before treatment, we explained in detail about diarrhea-inducing treatment by Gamsui-mal and patients agreed with treatment. The symptoms appeared in patients of diarrhea, abdominal pain, and vomiting in the treatment process. We evaluated the degree of improvement by visual analogue scale (VAS), oswestry disability index (ODI). After treatment, we found that pain was reduced and patient's symptoms were improved by visual analogue scale (VAS), oswestry disability index (ODI) score. The results show that diarrhea-inducing treatment by Gamsui-mal was rapidly improving symptoms. Further studies are needed to clarify the effect of diarrhea-inducing treatment by Gamsui-mal.

• 상하수도학회지
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• 제19권3호
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• pp.323-329
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• 2005

Advanced processes such as ozonation or activated carbon filtration (ACF) in water treatment plants have been used in Korea since 1994. At present, seventeen drinking water treatment plants are currently operating. This survey compares the treatment performance of advanced processes in eight plants which have comparable water quality data. The three parameters (DOC, $UV_{254}$, and $KMnO_4$ consumption) of water quality were selected as an indicator of treatment efficiency. The treatment efficiency of ozonation and ACF processes was found to vary with large deviations in each plant. Treatment efficiency of DOC, $UV_{254}$, and $KMnO_4$ consumption by post ozonation ranged from 3 to 11%, 6 to 33%, and 12 to 28% respectively. On the other hand, for ACF, treatment efficiency of DOC, $UV_{254}$, and $KMnO_4$ consumption ranged from 7 to 38%, 8 to 48%, and 16 to 66% respectively. These large deviations indicate the advanced processes of water treatment plants to be further optimized.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5455-5461
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• 2014

Background: Saponins are a major active component for the traditional Chinese medicine, Rubus parvifolius L., which has shown clear antitumor activities. However, the specific effects and mechanisms of saponins of Rubus parvifolius L. (SRP) remain unclear with regard to human chronic myeloid leukemia cells. The aim of this study was to investigate inhibition of proliferation and apoptosis induction effects of SRP in K562 cells and further elucidate its regulatory mechanisms. Materials and Methods: K562 cells were treated with different concentrations of SRP and MTT assays were performed to determine cell viability. Apoptosis induction by SRP was determined with FACS and DAPI staining analysis. Western blotting was used to detect expression of apoptosis and survival related genes. Specific inhibitors were added to confirm roles of STAT3 and AMPK pathways in SRP induction of apoptosis. Results: Our results indicated that SRP exhibited obvious inhibitory effects on the growth of K562 cells, and significantly induced apoptosis. Cleavage of pro-apoptotic proteins was dramatically increased after SRP exposure. SRP treatment also increased the activities of AMPK and JNK pathways, and inhibited the phosphorylation expression level of STAT3 in K562 cells. Inhibition of the AMPK pathway blocked the activation of JNK by SRP, indicating that SRP regulated the expression of JNK dependent oon the AMPK pathway. Furthermore, inhibition of the latter significantly conferred resistance to SRP pro-apoptotic activity, suggesting involvement of the AMPK pathway in induction of apoptosis. Pretreatment with a STAT3 inhibitor also augmented SRP induced growth inhibition and cell apoptosis, further confirming roles of the STAT3 pathway after SRP treatment. Conclusions: Our results demonstrated that SRP induce cell apoptosis through AMPK activation and STAT3 inhibition in K562 cells. This suggests the possibility of further developing SRP as an alternative treatment option, or perhaps using it as adjuvant chemotherapeutic agent for chronic myeloid leukemia therapy.

• Journal of Korean Neurosurgical Society
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• 제60권2호
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• pp.181-188
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• 2017

Objective : The objective of this study was to analyze the correlation between further compression and necrotic area in osteoporotic vertebral fracture (OVF) patients with contrast-enhanced magnetic resonance imaging (CEMRI). In addition, we investigated the radiological and clinical outcome according to the range of the necrotic area. Methods : Between 2012 and 2014, the study subjects were 82 OVF patients who did not undergo vertebroplasty or surgical treatment. The fracture areas examined on CEMRI at admission were defined as edematous if enhancement was seen and as necrotic if no enhancement was seen. The correlation between further compression and the necrotic and edematous areas of CEMRI, age, and bone mineral density was examined. Also, necrotic areas were classified into those with less than 25% (non-necrosis group) and those with more than 25% (necrosis group) according to the percentages of the entire vertebral body. For both groups, further compression and the changes in wedge and kyphotic angles were examined at admission and at 1 week, 3 months, and 6 months after admission, while the clinical outcomes were compared using the visual analog scale (VAS) and Eastern Cooperative Oncology Group (ECOG) performance status grade. Results : Further compression was $14.78{\pm}11.11%$ at 1 month and $21.75{\pm}14.43%$ at 6 months. There was a very strong correlation between the necrotic lesion of CEMRI and further compression (r=0.690, p<0.001). The compression of the necrosis group was $33.52{\pm}12.96%$, which was higher than that of the non-necrosis group, $14.96{\pm}10.34%$ (p<0.005). Also, there was a statistically significantly higher number of intervertebral cleft development and surgical treatments being performed in the necrosis group than in the non-necrosis group (p<0.005). Moreover, there was a statistical difference in the decrease in the height of the vertebral body, and an increase was observed in the kyphotic change of wedge angle progression. There was also a difference in the VAS and ECOG performance scales. Conclusion : The necrotic area of CEMRI in OVF had a strong correlation with further compression over time. In addition, with increasing necrosis, intervertebral clefts occurred more frequently, which induced kyphotic changes and resulted in poor clinical outcomes. Therefore, identifying necrotic areas by performing CEMRI on OVF patients would be helpful in determining their prognosis and treatment course.