• 제목/요약/키워드: functional role

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Diversity of Arbuscular Mycorrhizal Fungi and Their Roles in Ecosystems

  • Lee, Eun-Hwa;Eo, Ju-Kyeong;Ka, Kang-Hyeon;Eom, Ahn-Heum
    • Mycobiology
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    • 제41권3호
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    • pp.121-125
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    • 2013
  • Arbuscular mycorrhizal fungi (AMF) have mutualistic relationships with more than 80% of terrestrial plant species. This symbiotic relationship is ancient and would have had important roles in establishment of plants on land. Despite their abundance and wide range of relationship with plant species, AMF have shown low species diversity. However, molecular studies have suggested that diversity of these fungi may be much higher, and genetic variation of AMF is very high within a species and even within a single spore. Despite low diversity and lack of host specificity, various functions have been associated with plant growth responses to arbuscular mycorrhizal fungal colonization. In addition, different community composition of AMF affects plants differently, and plays a potential role in ecosystem variability and productivity. AMF have high functional diversity because different combinations of host plants and AMF have different effects on the various aspects of symbiosis. Consequently, recent studies have focused on the different functions of AMF according to their genetic resource and their roles in ecosystem functioning. This review summarizes taxonomic, genetic, and functional diversities of AMF and their roles in natural ecosystems.

CD29 및 CD98 활성 매개에 의한 Jurkat T 세포의 유착과 그 활용 (Cell-cell Adhesion of Jurkat T Cells Induced by CD29 and CD98 Activation and its Application)

  • 김병훈;조재열
    • 약학회지
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    • 제53권3호
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    • pp.119-124
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    • 2009
  • Cell-cell adhesion managed by various adhesion molecules plays an important role in regulating functional activation of cells. This event mediates attachment of inflammatory cells to endothelial cells, interaction of antigen-presenting cells with T cells and metastatic adherence of cancer cells to epithelial tissue cells. Therefore, this cellular response is considered as one of therapeutic target to treat various cancers and inflammatory diseases. To develop proper model for evaluation of functional activation of adhesion molecules, the ability of U937 and Jurkat T cells responsive to various adhesion inducers such as phorbal-12-myristate-13-acetate (PMA), staurosporin and monoclonal antibodies to CD29, CD43 and CD98 was investigated using quantitative cell-cell adhesion assay. U937 cells made more cell-cell clusters by the treatment of antibodies to CD29 and CD43 than Jurkat T cells, while Jurkat T cells exhibited increased cell-cell adhesion ability in CD98 antibody treatment. In agreement, the surface levels of CD29 and CD98 were highly observed in U937 and Jurkat T cells, respectively. Therefore, our data suggest that Jurkat T and U937 cells can be used for model system to evaluate functional activation of adhesion molecules such as CD29 and CD98.

Intraspecific Functional Variation of Arbuscular Mycorrhizal Fungi Originated from Single Population on Plant Growth

  • Lee, Eun-Hwa;Ka, Kang-Hyeon;Eom, Ahn-Heum
    • 한국균학회소식:학술대회논문집
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    • 한국균학회 2014년도 추계학술대회 및 정기총회
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    • pp.48-48
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    • 2014
  • Arbuscular Mycorrhizal Fungi(AMF) is widespread symbiont forming mutualistic relationship with plant root in terrestrial forest in ecosystem. They provide improved absorption of nutrient and water, and enhance the resistance against plant pathogen or polluted soil, therefore AM fungi are important for survival and maintaining of individual or community of plant. For last decade, many studies about the functional variation of AM fungi on host plant growth response were showed that different geographic isolates, even same species, have different effect on host plant. However, little was known about functional variation of AM fungal isolates originated single population, which provide important insight about intraspecific diversity of AMF and their role in forest ecosystem. In this study, four AM fungal isolates of Rhizophagus clarus were cultured in vitro using transformed carrot (Daucus carota) root and they showed the difference between isolates in ontogenic characteristics such as spore density and hyphal length. The plant growth response by mycorrhizas were measured also. After 20 weeks from inoculation of these isolates to host plants, dry weight, Root:Shoot ratio, colonization rates and N, P concentration of host plant showed host plant was affected differently by AM fungal isolates. This results suggest that AM fungi have high diversity in their functionality in intraspecific level, even in same population.

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Delaire 개념에 기반한 선천성 구순열의 치료 II: 기능적 구순비성형술 (Congenital Cleft Lip Repair Based on Delaire Philosophy II: Functional Cheilo-rhinoplasty)

  • 김성민;서미현;어미영;이석근;명훈;이종호;최진영
    • 대한구순구개열학회지
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    • 제13권2호
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    • pp.63-76
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    • 2010
  • After introduction of Delaire's basic philosophy, to consider the normal and pathologic anatomy, the role of some structures, such as nasal septum, musculature, and tongue, and some functions, such as dental occlusion or nasal respiration, which play important roles in maxillary and particularly premaxillary growth, on the Korean Journal of cleft lip and palate in 2009, Delaire's primary functional cheilorhinoplasty (FCR) in the unilateral and bilateral cleft lip patients was summarized and introduced according to already published literatures and lectures. This paper will be the second publishment of Delaire philosophy with Korean language.

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코카인 결합과 관련된 도파민 수송체의 아미노산 구조 (Amino Acid Structure of Dopamine Transporter Responsible for Cocaine Binding)

  • 장미윤;전대준;오동렬;이용성;이상훈
    • 약학회지
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    • 제43권6호
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    • pp.743-750
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    • 1999
  • Human and bovine dopamine transporters (DAT) demonstrate discrete functional differences in the dopamine (DA) transport and cocaine binding. The functional analyses on the chimeras of human and bovine DAT have revealed that the region from the $133^{rd}{\;}to{\;}186^{th}$ residue(encompassing the $3^{rd}$ trans-membrane domain (TM) is responsible for the substrate transport and cocaine binding. The present studies have been done to find out the specific amino acid(s) which is essential for the binding of cocaine to DAT by interchanging the amino acids in that region between human and bovine DAT. When isoleucine, the $152^{nd}$ residue of chimera B3 (bovine DAT sequence) was transformed back to valine, the human DAT residue at the identical position, the cocaine binding was remarkably recovered to 98% of the human DAT values. In addition, the cocaine binding of the human DAT was decreased by 57% by substituting isoleucine for valine at position 152. When isoleucine at position 152 of the chimera B3 was converted to the other amino acids to provide an possible molecular basis for the functional role of the $152^{nd}$ residue, only the conversion to alanine among acids tested significantly the cocaine by 34%, but these effect were not as much as those by the conversion to valine. In conclusion, valine at position 152 is a crucial amino acid for the interaction of cocaine to the DAT.

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항균제의 항균특성 및 악취제거 효과 (Antimicrobial Characterictics of Antimicrobial Agent (Antibiotics) and Reduction Effect on Mal-ordour.)

  • 신춘환;김종현;한선홍
    • 한국환경과학회지
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    • 제3권2호
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    • pp.157-164
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    • 1994
  • Various antimicrobial agents are widely used for the purpose of antimicrobial process. We investigated antimicrobial activity and reduction efficiency of mal-ordour by the diphenyl ether compound (2,4,4'- trichloro -2'- hydroxy diphenyl ether) against Sraphylocom aureus(S.aureus and Proton vulgaris(p.vulgaris causing the mal-ordour, Especially, the diphenyl ether compound is not restricted to the regulation of water-contamination. In this research, we found that the optimum concentration of diphenyl ether compound was 1.5w% for both strains and antimicrobial expressions were c0.38t= 2.56 for S.aureus, c0.38t=2.67 for P.vulgaris. We found also that -OH group played the role of antimicrobial functional group. Lastly, reduction effect of mal-ordour was more than 90% for both strain at the optimum conditions. Key Words : antimicrobial agents, antimicrobial activity, reduction effect of mal-ordour, antimicrobial expression, antimicrobial functional group.

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Estimation of Reward Probability in the Fronto-parietal Functional Network: An fMRI Study

  • Shin, Yeonsoon;Kim, Hye-young;Min, Seokyoung;Han, Sanghoon
    • 감성과학
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    • 제20권4호
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    • pp.101-112
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    • 2017
  • We investigated the neural representation of reward probability recognition and its neural connectivity with other regions of the brain. Using functional magnetic resonance imaging (fMRI), we used a simple guessing task with different probabilities of obtaining rewards across trials to assay local and global regions processing reward probability. The results of whole brain analysis demonstrated that lateral prefrontal cortex, inferior parietal lobe, and postcentral gyrus were activated during probability-based decision making. Specifically, the higher the expected value was, the more these regions were activated. Fronto-parietal connectivity, comprising inferior parietal regions and right lateral prefrontal cortex, conjointly engaged during high reward probability recognition compared to low reward condition, regardless of whether the reward information was extrinsically presented. Finally, the result of a regression analysis identified that cortico-subcortical connectivity was strengthened during the high reward anticipation for the subjects with higher cognitive impulsivity. Our findings demonstrate that interregional functional involvement is involved in valuation based on reward probability and that personality trait such as cognitive impulsivity plays a role in modulating the connectivity among different brain regions.

The Syntheses and Application of NIR Dyes Based On Light Absorbing Properties

  • Park, Soo-Youl;Shin, Seung-Rim;Shin, Joung-Il;An, Kyoung-Lyong;Lee, Sang-Oh;Jun, Kun
    • 한국염색가공학회:학술대회논문집
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    • 한국염색가공학회 2010년도 제3회 국제학회
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    • pp.49-50
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    • 2010
  • The near-infrared absorbing donor-acceptor chromophores have been investigated by varying the electron donating and accepting molecular moiety. A series of near-infrared absorbing chromophores were offered narrow and intense absorption band in a various organic solvents. The dyes synthesised were, however, strongly bathochromic shift which extended well into the near-infrared region. The functional uses of dyes are vast in number, and it is convenient to classify them in some way. In all cases, it is the $\Pi$-chromophore that plays a major role in the functional application. "Light absorption" is of course the most commonly used property of a dye chromophore, and it can be employed directly, e.g. in light filters and optical data recording, or it can be used to drive further functional processes, e.g. fluorescence, photochromism, photosensitization.

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Correlations among Motor Function, Quality of Life, and Caregiver Depression Levels in Children with Cerebral Palsy

  • Yoo, Ji-Na
    • The Journal of Korean Physical Therapy
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    • 제28권6호
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    • pp.385-392
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    • 2016
  • Purpose: This study aimed to evaluate the relationships among quality of life, caregiver depression levels, and disease severity, especially motor function, in children with cerebral palsy. Methods: Data were collected through questionnaires using survey and interview from 80 caregivers of children with cerebral palsy. The caregivers' quality of life was measured using medical outcomes study 36-item short form health survey, and level of depression was scored using the beck depression inventory. In addition, children's motor function was evaluated using gross motor function measure-88 and functional independence measure scores. Results: Among 8 domains of medical outcomes study 36-item short form health survey, "physical functioning," "physical role functioning," "mental health," and "bodily pain" domains were significantly correlated to "total" percentage scores of gross motor function measure-88. In addition, "mental health" and "bodily pain" domains were correlated to each sub-dimension, including "lying and rolling," "sitting," "crawling and kneeling," "standing," and "walking, running, and jumping." Similarly, the "running" and "jumping" dimensions including motor function measures correlated with "transfer," "locomotion," and "motor subtotal" of functional independence measure scores. The beck depression inventory scores were negatively correlated to "lying and rolling," "sitting," "crawling and kneeling," and the "total" percentage scores of gross motor function measure-88. The beck depression inventory scores were negatively correlated to "sphincter control," "communication," "social cognition," "cognitive subtotal," and "total" functional independence measure scores. Conclusion: It is necessary to consider the quality of life and emotional problems of caregivers of CP children and support them both physically and psychologically with comprehensive rehabilitation.

Enhanced binding between metals and CNT surface mediated by oxygen

  • 박미나;김병현;이광렬
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2009년도 제38회 동계학술대회 초록집
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    • pp.61-61
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    • 2010
  • In the present work, we present the optimized the hybrid structures of carbon nanotubes (CNTs) and metal nanocomposites including Cu, Al, Co and Ni using the first principle calculations based on the density functional theory. Introduction of CNTs into a metal matrix has been considered to improve the mechanical properties of the metal matrix. However, the binding energy between metals and pristine CNTs wall is known to be so small that the interfacial slip between CNTs and the matrix occurs at a relatively low external stress. The application of defective or functionalized CNTs has thus attracted great attention to enhance the interfacial strength of CNT/metal nanocomposites. Herein, we design the various hybrid structures of the single wall CNT/metal complexes and characterize the interaction between single wall CNTs and various metals such as Cu, Al, Co or Ni. First, differences in the binding energies or electronic structures of the CNT/metal complexes with the topological defects, such as the Stone-Wales and vacancy, are compared. Second, the characteristics of functionalized CNTs with various surface functional groups, such as -O, -COOH, -OH interacting with metals are investigated.We found that the binding energy can be enhanced by the surface functional group including oxygen since the oxygen atom can mediate and reinforce the interaction between carbon and metal. The binding energy is also greatly increased when it is absorbed on the defects of CNTs. These results strongly support the recent experimental work which suggested the oxygen on the interface playing an important role in the excellent mechanical properties of the CNT-Cu composite[1].

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