• 한국건설관리학회논문집
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• 제14권2호
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• pp.56-64
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• 2013

안전사고와 민원이 많은 건설현장에서 새로운 건설기술, 특히 자동화 장비가 적용되는 경우는 드물다. 본 연구에서는 건설 자동화 장비의 적용 가능성을 높이기 위하여 고려하여야 하는 기술도입 영향요인들을 도출하고 분석하였다. 먼저, 영향요인들을 기술과 비기술 요인으로 분류하고, 기술요인을 사용성과 기능성 요인으로, 그리고 비기술 요인을 비용, 공사특징, 조직요인으로 분류하였다. 다음으로, 전문가 설문을 통하여 각 영향요인들의 중요도와 실현 가능성을 분석하였다. 사용성과 기능성이 중요도와 실현 가능성이 모두 높은 요인으로 분석되었다. 또한, 영향요인들의 중요도와 실현 가능성에 대한 건설사와 장비 개발사의 관점 차이를 분석하였다. 사전관계와 운전자 태도, 구성원들 의지, 공사품질들은 모두 건설사가 장비 개발사보다 더 높게 인식하고 있었다. 본 연구의 결과를 기반으로 장비 개발사는 건설사와의 관점 차이를 인지하고, 건설사가 중요하게 생각하는 요인들을 중심으로 개발하여야 할 것이다. 또한 본 연구의 결과는 자동화 장비 개발 사전 단계에서 적용할 수 있는 평가기준으로 활용될 수 있을 것이다.

• 대한안전경영과학회지
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• 제26권1호
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• pp.55-61
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• 2024

In this paper, in order to study the relationship between the safety culture of highway management agencies and disaster reduction activities (BCMS), a measurement tool was identified through previous research on safety culture, and the validity of the measurement tool was confirmed through exploratory factor analysis. I want to check. The subjects of the study were workers belonging to disaster reduction activity management system certification organizations among highway management organizations. The highway management agencies are the Korea Expressway Corporation, which manages the functional continuity of national highways nationwide, and 8 of the 21 private road agencies that manage the functional continuity of the highways. The safety culture measurement tool is an indicator that measures safety culture factors, and is reorganized by the researcher based on survey items from previous studies, with management/manager safety values and attitudes, safety communication, safety education and training, and safety regulations/management system as subfactors. A total of 24 questions were comprised of the survey tool. As a result of the study, the result of exploratory factor analysis was that the safety culture scale was extracted into four factors based on theoretical grounds, and the total cumulative variance was 80.360%. When checking the questions for each factor, it was found that all the questions loaded on the factor that was originally intended to be measured. Factor 1 is management, factor 2 is safety, and factor 3 is communication., Factor 4 was named education. Number of questions: 4 management questions, 3 safety questions, communication It consisted of 4 questions and 2 education questions.

• 한국의류산업학회지
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• 제12권5호
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• pp.599-607
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• 2010

This study analyzed how the self-efficacy and commitment on functional satisfaction and repurchase intentionof mountaineering apparels. The survey was conducted over the climbers with 298 subjects. The statistical analysis methods were frequency analysis, factor analysis, reliability analysis, and regression analysis. The results showed that the self-efficacy of climbers were classified into self-regulated efficacy, self-confidence, and task difficulty preference, and the commitment of climbers were classified into behavioral commitment and cognitive commitment. The self-regulated efficacy and self-confidence influenced the behavioral commitment and the self-regulated efficacy influenced the cognitive commitment. The behavioral commitment and cognitive commitment influenced the functional satisfaction and repurchase intention of mountaineering apparels. The functional satisfaction influenced the repurchase intention of mountaineering apparels.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제21권4호
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• pp.264-270
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• 2018

Purpose: The aim of this study was to describe functional gastrointestinal disorders (FGID) presented in a tertiary medical center, characteristics of patients and results of the diagnostic work-up together with an outcome during the follow up. Methods: This was a retrospective, single center, observational study including all patients who were diagnosed with FGID based on Rome III criteria from January to December 2015 in tertiary medical center. Results: Overall 294 children were included (mean age, 8.9 years [range, 1-18 years]; 165 females). Majority had functional constipation (35.4%), followed by functional abdominal pain (30.6%), irritable bowel syndrome (17.0%), functional dyspepsia (12.6%), functional nausea (3.4%) and abdominal migraine (1.0%). Regression model found that only significant factor associated with improvement of symptoms is the establishment of the functional diagnosis at the first visit (hazard ratio, 2.163; 95% confidence inverval, 1.029-4.544). There was no association between improvement of symptoms and presence of alarm signs/symptoms (weight loss, nocturnal symptoms and severe vomiting) at diagnosis. Furthermore, in pain symptoms (functional abdominal pain, irritable bowel syndrome, dyspepsia) no treatment positively correlated with pain improvement. Conclusion: Regardless of the initial diagnosis of FGID, positive diagnosis at the first visit increases a chance for resolution of symptoms.

• 한국조리학회지
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• 제12권4호
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• pp.116-130
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• 2006

This research was accomplished to analyze the preference and the actual using patterns of the bakery products using functional ingredients by subjects' age. This survey was examined by the self-administered questionnaire method for 374 female subjects in Suwon. All respondents preferred breads than confectionaries with functional ingredients. As for the products of cooking ingredients, cookies, roll-cake, cake, chocolate, the preference of teenagers was higher than those of the other groups. Subjects preferred potatoes, fruits, rice and green tea as functional ingredients. Over thirties showed the high preference over beans, vegetables, mushrooms, ginseng and oriental herbs while fruits were highly preferred in teenagers and twenties. The ratio of using the bakery products with functional ingredients once or twice a week was higher in over thirties than those of the other groups. Subjects answered that they generally spent $3,000won\sim5,000won$ on those products. Functionality of products was considered as the more important factor in thirties than in the other groups. The lack of information about these products and functional ingredients was reported by teenagers and twenties. These results would be basic data for marketing or improvement of baking products with functional ingredients.

• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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• pp.70-70
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• 2002

• 한국생활과학회지
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• 제19권2호
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• pp.389-398
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• 2010

This study examines the relationship between the concern about well-being lifestyle and the perceived image of Hanji fiber. A survey was conducted among male and female consumers aged 20 and over in Jeonju and Daejon from January 4th to 11th, 2008. A total of 168 responses were analyzed by using descriptive statistics, factor analysis, and ANOVA via the SPSS ver. 12. As a result, four factors were determined in the concern for a well-being lifestyle; product consumption, enjoying culture, using therapy and managing the household. The perceived image of Hanji fiber were classified into four elements; traditional, high-quality, functional and popular images. Among the factors of the concern for a well-being lifestyle and the perceived image of Hanji fibers, a partial relationship was observed. There is a positive relationship, especially between the product consumption factor of a well-being lifestyle and the high-quality and functional image of Hanji fiber. Also, there was a positive relationship between the factor of managing the household and the traditional image of Hanji fiber. However, the therapy interest factor of a well-being lifestyle was negatively related to the traditional image of Hanji fiber.

• Genomics & Informatics
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• 제6권2호
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• pp.72-76
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• 2008

Hypoxia-inducible factor $1{\alpha}\;(HIF1{\alpha})$ is a transcription factor that plays a key role in the adaptation of cells to low oxygen stress and oxygen homeostasis. The oxygen-dependent degradation (ODD) domain of $HIF1{\alpha}$ is responsible for the negative regulation of $HIF1{\alpha}$ in normoxia. The interactions of the $HIF1{\alpha}$ ODD domain with partner proteins such as von Hippel-Lindau tumor suppressor (pVHL) and p53 are mediated by two sequence motifs, the N- and C-terminal ODD(NODD and CODD). Multiple sequence alignment with $HIF1{\alpha}$ homologs from human, monkey, pig, rat, mouse, chicken, frog, and zebrafish has demonstrated that the NODD and CODD motifs have noticeably high conservation of the primary sequence across different species and isoforms. In this study, we carried out molecular dynamics simulation of the structure of the $HIF1{\alpha}$ CODD motif in complex with the p53 DNA-binding domain (DBD). The structure reveals specific functional roles of highly conserved residues in the CODD sequence motif of $HIF1{\alpha}$ for the recognition of p53.

• Journal of Korean Neurosurgical Society
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• 제62권2호
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• pp.153-165
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• 2019

Objective : Spinal cord injury (SCI) is a very serious health problem, usually caused by a trauma and accompanied by elevated levels of inflammation indicators. Stem cell-based therapy is promising some valuable strategies for its functional recovery. Nestin-positive progenitor and/or stem cells (SC) isolated from pancreatic islets (PI) show mesenchymal stem cell (MSC) characteristics. For this reason, we aimed to analyze the effects of rat pancreatic islet derived stem cell (rPI-SC) delivery on functional recovery, as well as the levels of inflammation factors following SCI. Methods : rPI-SCs were isolated, cultured and their MSC characteristics were determined through flow cytometry and immunofluorescence analysis. The experimental rat population was divided into three groups : 1) laminectomy & trauma, 2) laminectomy & trauma & phosphate-buffered saline (PBS), and 3) laminectomy+trauma+SCs. Green fluorescent protein (GFP) labelled rPI-SCs were transplanted into the injured rat spinal cord. Their motilities were evaluated with Basso, Beattie and Bresnahan (BBB) Score. After 4-weeks, spinal cord sections were analyzed for GFP labeled SCs and stained for vimentin, $S100{\beta}$, brain derived neurotrophic factor (BDNF), 2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNPase), vascular endothelial growth factor (VEGF) and proinflammatory (interleukin [IL]-6, transforming growth factor $[TGF]-{\beta}$, macrophage inflammatory protein [MIP]-2, myeloperoxidase [MPO]) and anti-inflammatory (IL-1 receptor antagonis) factors. Results : rPI-SCs were revealed to display MSC characteristics and express neural and glial cell markers including BDNF, glial fibrillary acidic protein (GFAP), fibronectin, microtubule associated protein-2a,b (MAP2a,b), ${\beta}3$-tubulin and nestin as well as anti-inflammatory prostaglandin E2 receptor, EP3. The BBB scores showed significant motor recovery in group 3. GFP-labelled cells were localized on the injury site. In addition, decreased proinflammatory factor levels and increased intensity of anti-inflammatory factors were determined. Conclusion : Transplantation of PI-SCs might be an effective strategy to improve functional recovery following spinal cord trauma.

• 한국콘텐츠학회논문지
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• 제22권8호
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• pp.159-169
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• 2022

본 연구는 행동경제학(Behavioral Economics) 관점을 적용하여 이용자들이 OTT 플랫폼을 지속적으로 이용함에 있어서 영향을 미치는 요인을 탐색하였다. OTT 이용자들이 실제 콘텐츠를 시청하고 플랫폼에서 제공하는 기능을 직접 경험한 후 만족을 느끼는 합리적 요인 외에도 '현상유지 편향(status quo bias)'에 의한 습관적 요인과 지인, 비용 등 상황에 따른 감정적, 심리적 요인도 영향을 미칠 것으로 판단했다. OTT 이용자들을 대상으로 한 심층 인터뷰와 선행 연구들을 통해 도출한 4가지 요인(콘텐츠 만족요인, 기능적 만족요인, 관성적 요인, 상황적 요인)에 대한 세부 문항을 구성하고, 국내 구독자 Top3 OTT 플랫폼(넷플릭스, 웨이브, 티빙)의 이용경험이 있는 전국의 20-40대 성인남녀 523명을 대상으로 온라인 설문조사를 실시하였다. 분석결과, '콘텐츠 만족요인'과 '기능적 만족요인', '관성적 요인'이 OTT 지속적 이용에 유의미한 영향을 미치는 것으로 나타났으며, 이 중 '관성적 요인'은 국내 OTT 이용자들에게는 영향을 미치지 않았다. 본 연구는 OTT 서비스 이용자들을 완전한 합리성을 갖춘 존재로 전제했던 기존의 선행연구들과는 다르게 제한적 합리성을 함께 고려하여 OTT 지속적 이용 행위에 대한 설명의 범위를 넓혔다는 의의를 가진다.