• Polymer(Korea)
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• v.33 no.1
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• pp.45-51
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• 2009

Water soluble adhesive was polymerized from butyl acrylate (BA), methyl methacrylate (MMA) and one of various functional monomers such as acrylic acid (AA), 2-hydroxylethyl methacrylate (2-HEMA), glycidyl methacrylic acid (GMA) and acrylamide (AAm). The amount of the functional monomers was 1$\sim$5 wt%/monomer. In order to improve the adhesive power, a substrate was treated using atmospheric flat plasma method. The adhesive power was improved by the addition of the functional monomers with an order of AA> 2-HEMA> GMA> AAm. The holding power of the adhesives, which is related with the thermal properties of the adhesives, increased with the amount of the functional monomers. The effectiveness in improving the holding power has an order of AA > AAm > GMA > 2-HEMA. By treating a substrate with atmospheric flat plasma method, the adhesives containing each of AA, 2-HEMA, GMA and AAm showed the increases of the final adhesion strength by 9.1, 9.4, 9.4, and 1.8%, respectively. In conclusion, the mechanical properties such as adhesive power and holding power could be controlled by introducing.

• Journal of The Korean Society of Integrative Medicine
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• v.9 no.4
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• pp.167-181
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• 2021

Purpose : This study was conducted to investigate whether phonetic complexity affected the type and frequency of articulation errors and the acoustic duration of consonants and words produced by children with functional articulation and phonological disorders. Methods : The participants in this study were 20 children with functional articulation and phonological disorders and 20 children without such disorders who were between 3 years 7 months old and 4 years 11 months old. The participants were asked to name what they saw in pictures and their responses were recorded. The types and frequencies of articulation errors and the acoustic duration of words were analyzed and words were categorized as being of either 'high' or 'low' phonetic complexity. The acoustic duration of initial and final consonants and vowels following initial consonants were compared between the groups according to articulatory complexity. Results : Children with functional articulation and phonological disorders produced articulation errors more frequently when saying high complexity words and had longer word duration when saying low-complexity words than children without such disorders. There was no major difference in initial and final consonant duration between the groups. but the main effect of articulatory complexity on the duration of both consonants was significant. Conclusion : These results suggest that the articulatory-phonic structure of words influences the speech motor control ability of children with functional articulation and phonological disorders. When articulating consonants, children with functional articulation and phonological disorders had speech motor control ability similar to that of children without such disorders.

• Journal of Convergence for Information Technology
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• v.12 no.1
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• pp.45-54
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• 2022

The purpose of this study was to identify affecting factors on health behaviors among university students. A cross-sectional study was conducted with a sample of 161 participants between May and June 2020. The authors assessed functional health literacy, health self-efficacy, and health behaviors. Mean score of functional health literacy and health self-efficacy was 10.14±1.39 and 3.96±0.60, respectively. Of the subjects, 9.9% were smokers, 23.0% were problem drinking, 96.9% were those who needed monitoring of their eating habits, 63.4% were those with low or moderate physical activity, and 29.8% were those who were overweight or obesity. Gender and functional health literacy had an effect on smoking and eating habits, respectively. Gender and health self-efficacy were affecting factors on physical activity. Researchers should be sought strategies to promote health behavior considering gender, functional health literacy and health self-efficacy.

• The Journal of Internal Korean Medicine
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• v.43 no.5
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• pp.918-928
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• 2022

Objectives: This study reports on the efficacy of Korean medical treatments for a functional dyspepsia patient with panic disorder and lower back pain. Methods: A 51-year-old male patient with functional dyspepsia was treated with herbal medicines and acupuncture for 17 days. The treatment effect was evaluated by measurements drawn from the Numerical Rating Scale, range of motion, Oswestry Disability Index, European Quality of Life 5 Dimensions Scale, and Gastrointestinal Symptom Score. Results: Following the treatment, the patient showed a decrease on the Numerical Rating Scale and Oswestry Disability Index and in Gastrointestinal Symptom Score, as well as an improvement in range of motion and European Quality of Life 5 Dimensions score. Conclusions: Korean medical treatments appear to be effective in reducing functional dyspepsia. Further clinical research on patients with functional dyspepsia is needed.

• Journal of Dairy Science and Biotechnology
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• v.34 no.2
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• pp.117-135
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• 2016

The present study was performed to develop a functional raw food material from hydrolyzed whey protein powder (23%-GNANA) medication containing sialic acid as a marker compound that is naturally occurring at 7% concentration in GMP (glycomacropeptide). GMP is used worldwide in foodstuffs for babies and infants and is obtained from the milk protein as safe food. While the purpose of our detailed evaluation was aimed to assess preliminary NOAEL values for and above 2,000 mg/kg/day, a clinical dose allowance for 23%-GNANA (as per characteristic of a functional health product, a highly refined test substance of 23% (v/v) sialic acid combined in GMP), at the same time we also wanted to assess the safety of GMP hydrolyzate lacking sialic acid but with identical properties as GMP. Animal safety evaluation was conducted using 23%-GNANA as the test substance, produced from hydrolyzed whey protein powder (product name: HELICOBACTROL-23; provided by Medinutrol Inc. [Korea]; composed of 23% sialic acid and GMP protein) after isolating the sialic acid using enzymes approved as food additives, with GMP as a raw material, and subsequently increasing the content of xx up to 23% through 80% (v/v) ethanol soaking and concentrating, in accordance with GLP Guideline. The animal safety evaluation mentioned above was made on the basis of toxicity in SPF Sprague-Dawley female and male rats dosed with 10 mL of the test substance diluted to 0, 1,250, 2,500, and 5,000 mg/kg directly into their stomachs for 90 d. This was determined in terms of the general symptoms and animal viability, weight and amount of feed intake, eye examination, uracrasia tests, hematological and blood biochemical disorder tests, blood coagulation test, abnormal intestine weight, abnormalities during postmortem and histopathological examinations. Statistical significance was set at P<0.05. Based on the toxicity determination, a certain minor effect associated with the test substance was observed in male rats with no major effects of the tested substance, in comparison with the control group dosed with sterilized water. Nevertheless, the NOAEL value, evaluated as per toxicity criteria, was verified as 5,000 mg/kg/day (P<0.05). Similarly, for female rats, a certain minor effect associated with the test substance was observed in 5,000 mg/kg/day dosed group, with no major effect, yet the NOAEL value (as assessed as per toxicity criteria) was determined to be 5,000 mg/kg/day (P<0.05), which was the same as for male rats. Accordingly, the NOAEL values of the test substances for all female and male rats were finally verified as 5,000 mg/kg/day (P<0.05). In conclusion, it was determined that the 23%-GNANA test substance exceeds 2,000 mg/kg/day, the clinical allowance characteristic for functional health food, and was finally evaluated to cause no safety concerns when used as a raw material in functional health food production, which was the ultimate goal of the present study.

• Korean Journal of Breeding Science
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• v.42 no.4
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• pp.407-412
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• 2010

Recently, peoples are greatly concerned with global temperature change because global warming can be a potential serious effect on agriculture production such as yield reduction and poor grain quality. On the other hand, it can bring some beneficial effects through twice cultivation of rice in temperate region. In order to overcome this situation, we developed extremely early-maturing rice 'Milyang255' which heading date was similar with 'Jinbuolbyeo'. Based on agronomic characteristics of 'Milyang255', it has very short stature as 65 cm of culm length and slightly lower spikelets number per panicle compared with that of 'Jinbuolbyeo'. However, the grain appearance, palatability and other items were better than those of 'Jinbuolbyeo' in panel test of cooked rice. The milled rice yield of 'Milyang255' is 3.94 MT/ha at the early transplanting. Especially, its grain filling rate was higher and faster than Jinbuolbyeo and the head rice ratio in milled rice was also higher. Thus, 'Milyang255' can efficiently reduce the growth duration of rice cultivation and also be useful material for research on twice cultivation of rice in Korea.

• Journal of the Korean Vacuum Society
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• v.18 no.2
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• pp.147-150
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• 2009

We present a technique for fabricating low leakage organic field-effect transistors by a functional polydimethylsiloxane (PDMS) layer. The technique relies on the photo-chemical process of conversion of the PDMS to a silicon oxide which provides the selective growth of pentacene thin films. The reduced gate leakage current showed ${\sim}10^{-10}$ A in a linear ($V_d=-5\;V$) and saturation ($V_d=-30\;V$) region at $V_g-V_t>0$.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.4
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• pp.460-464
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• 2013

The purpose of this case was to report the effect of Korean medical treatment for patient with pleural effusion due to congestive heart failure. The patient was treated with herbal medicine(Cheongsingeonbi-tang) and acupuncture. The effect of treatment was evaluated by chest X-ray, New York Heart Association(NYHA) functional classification, and Hugh-Jones classification. After 3 weeks of treatment, the amount of pleural effusion was decreased and NYHA class, Hugh-Jones grade were improved. NYHA functional classification improved class III to II and Hugh-Jones classification changed grade IV to II. This result suggests that herbal medicine(Cheongsingeonbi-tang) and acupuncture treatment might have an effect on patient with pleural effusion due to congestive heart failure.

• Nutrition Research and Practice
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• v.5 no.2
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• pp.93-100
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• 2011

Inhibition of angiotensin I-converting enzyme (ACE) activity is the most common mechanism underlying the lowering of blood pressure. In the present study, five organic extracts of a marine brown seaweed Ecklonia cava were prepared by using ethanol, ethyl acetate, chloroform, hexane, and diethyl ether as solvents, which were then tested for their potential ACE inhibitory activities. Ethanol extract showed the strongest ACE inhibitory activity with an $IC_{50}$ value of 0.96 mg/ml. Five kinds of phlorotannins, phloroglucinol, triphlorethol-A, eckol, dieckol, and eckstolonol, were isolated from ethanol extract of E. cava, which exhibited potential ACE inhibition. Dieckol was the most potent ACE inhibitor and was found to be a non-competitive inhibitor against ACE according to Lineweaver-Burk plots. Dieckol had an inducible effect on the production of NO in EAhy926 cells without having cytotoxic effect. The results of this study indicate that E. cava could be a potential source of phlorotalnnins with ACE inhibitory activity for utilization in production of functional foods.

• The Korean Journal of Food And Nutrition
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• v.23 no.1
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• pp.15-22
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• 2010

This study was conducted to evaluate the antioxidative effect and antimutagenic capacity of ethanol extracts of Flammulina velutipes by employing biological and biochemical assays. The $IC_{50}$ of MDA with BSA conjugation reaction, lipid peroxidation and scavenging effect on DPPH radical in ethanol extracts of Flammulina velutipes was found to be 28.39 mg/assay, 9.33 mg/assay and 144.61 mg/assay respectively. Therefore, the most effective antioxidative capacity of ethanol extracts of Flammulina velutipes was $Fe^+$-induced linoleate peroxidation, among the method used this study. The indirect and direct antimutagenic effects of the ethanol extracts of Flammulina velutipes were examined by the Ames test using Salmonella typimurium TA98 and TA100. The inhibition rates on indirect mutagenicity mediated by 2-anthramine and on direct mutagenicity mediated by sodium azide in Salmonella typimurium TA100 and mediated by 2-nitrofluorene in Salmonella typimurium TA98 were 0%, respectively. These findings indicate that ethanol extracts of Flammulina velutipes have no effects on indirect and direct mutagenicity. Based on these results, it believed that the ethanol extracts of Flammulina velutipes has antioxidative capacities, and is a the candidate for the prevention and dietetic treatment of chronic diseases and the development of antioxidative functional food.