• The Journal of Korean Obstetrics and Gynecology
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• v.22 no.1
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• pp.182-190
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• 2009

Purpose: The pilot study was done for checking the efficacy of using functional soap, containing medicinal herbs on acne skin. Methods: 30 participants with acne skin was recruited. They used functional soap during 8 weeks. Before and after the study, we checked the KAGS(Korean Acne Grading System) grade, and compared those score. For examining the clinical effect, global evaluation was done by both investigator and participants. Results: KAGS grade decreased from 1.6316 to 1.4211(p value = 0.042). And the clinical global evaluation was improved. Conclusion: This pilot test showed that using functional soap, containing medicinal herbs would be one of treatment on acne skin.

• Journal of the Korean Society of Food Culture
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• v.38 no.6
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• pp.456-464
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• 2023

The purpose of this study was to investigate nutritional and functional ingredients and antioxidant activity after fermenting rice bran using Lactobacillus brevis for 24, 36, and 48 hours. The results of the analysis of the nutritional ingredients revealed that there was no significant difference in the carbohydrate, crude protein, crude fat and ash content regardless of the fermentation process and fermentation time. The amount of dietary fiber was significantly different between the unfermented and fermented rice bran and was observed to be the highest after a 48-hour fermentation. The γ-oryzanol, gamma-aminobutyric acid (GABA) and total phenolic contents were significantly higher in the fermented rice bran compared to the unfermented rice bran (p<0.05) and the GABA and total phenolic contents increased significantly as the fermentation time increased (p<0.05). The 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-azino-bis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS), superoxide and hydroxyl radical scavenging activities used to measure antioxidant effects significantly increased as the fermentation time increased (p<0.05). From these results, it was confirmed that the antioxidant effect and functional components, namely γ-oryzanol, GABA, and the total phenolic content of rice bran improved with fermentation. Based on these results, fermented rice bran could be presented as a functional material for use in high value-added industries.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.1
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• pp.37-43
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• 2003

Dam-eum(痰飮) is peculiar pathological product which is caused by functional difficulty in human fluid replacement and that principally originated functional difficulty between Lung(肺), Spleen(脾), Kidney(腎) and Sam-Cho(三焦). Dam-eum(痰飮) comes into force to disorder about ascending, decending, in and out of human energy circulation and frequently raises functional difficulty in human fluid replacement. As a result of that, it has much effect on action of Spirit(神志). After literatual study on the effect of Dam-eum(痰飮) on Spirit(神志), the result were obtained as follows : Dam-eum is not affecting to Spirit by itself. When Dam-eum is Positive Symptom(實證), Yang Symptom(陽證), mainly it affects to Spirit with Pung(風), Hwa(火), Kyung(驚), Youl(熱). And when it is Negative Symptom(虛症), it mostly affects with 脾胃虛寒, 心血不足. Dam-eum is a factor of causing disharmony between Heart & Kidney(心腎), Heart & Liver(心肝), Stomach & Gall Bladder Line(胃膽經) by 痰迷心竅, 痰火擾心. So it brings out troubles of fluid replacement. These are the main circumstances of affecting Spirit. To cure Disease of Spirit(神志病), which is caused by Dam-eum, there are not only uses the treatment of 理痰氣, 豁痰開竅. There are two treatments to use together. The first treatment is 淸熱, 定驚, 息風, 淸心 that removes fitted toxin. And the other treatment is that keeps the balance of Internal Organs.

• The Research Journal of the Costume Culture
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• v.24 no.3
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• pp.358-366
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• 2016

This study was performed to measure the posture correction effect of wearing ergonomic experimental clothing. Two types of experimental clothing (A, B) were developed. Both of them reinforced the muscles surrounding the spine. Experimental clothing A was developed by reflecting the shape and position of the pectoralis major muscle, abdominal muscle, and latissimus dorsi muscle. Experiment clothing B was developed by reflecting the integrated form of those muscles. Subjects were males in their 20s~30s (n=32). They were divided into two groups based on their acromion distance (AD): the turtle neck syndrome group (n=16, AD=3.81cm) and the normal group (n=16, AD=1.27cm). The correction of body posture was detected by three index values: change of the cervical curvature angle, horizontal distance between the seventh cervical vertebra and tragion, and AD. The comfort and tightness of the clothing were also measured. The results showed that both types of experimental clothing corrected body posture and that turtle neck syndrome can be prevented by wearing these types of posture correcting clothing. Two index values were decreased: cervical curvature angle ($0.31{\sim}1.32^{\circ}$) and horizontal distance between seventh cervical vertebra and tragion (0.22~0.31cm). The chest was also stretched. The comfort was rated as good for both types of experimental clothing. These results indicate that the experimental clothing had a posture correction effect without any discomfort for daily living.

• The Journal of the Korea Contents Association
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• v.16 no.11
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• pp.464-476
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• 2016

The purpose of this research was conducted to provide an implication on the practical strategy method to enhance the awareness of University competitiveness. This research examined the various relations among emotional, social, functional values along with Brand attitude and intentioned action of University Tae-Kwon-Do Competition. Samples were 314 attendees of student and parents at the 2015 University Tae-Kwon-Do competition in Busan area. Collected data was first analysed by exploratory factor analysis then proposed conceptual framework was tested via confirmatory factor analysis and structural equation modelling. The results were as follows: First, emotional and social values of University Tae-Kwon-Do competition had a significant effect on the Brand attitude, however, functional value showed no effect on intended action. Second, emotional, social, functional values of University Tae-Kwon-Do Competition had a significant effect on the intended action. Third, Brand attitude of University Tae-Kwon-Do Competition showed statistical relativeness with intended action.

• The Korean Journal of Food And Nutrition
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• v.25 no.1
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• pp.181-187
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• 2012

Grifola frondosa has been used as an herbal medicine for the treatment of cancer, diabetes mellitus and high blood pressure. In this study, functional polysaccharide was obtained from Grifola frondosa using four different extraction methods: hot water(HwFP), homogenize(HgFP), acid(AcFP), and alkali(AlFP) extraction methods. The effects of these extracts on KB and HepG2 cell lines were then examined for any anti-cancer activity. Alkaline extraction produced a yield of 0.175% and the total sugar content of the extract was 54.97%. We were able to confirm that the polysaccharide extracts from the mushroom produce an anti-cancer effect. The cytotoxicity of AlFP and AcFP against HepG2 cells were 22.86% and 28.88%, respectively, and the cytotoxicity of AlFP against the KB cell lines was 47.76% at a concentration of 1,000 ${\mu}g/m{\ell}$. Therefore, these results suggest that the optimum method for extracting functional polysaccharides from G. frondosa is the alkali extraction method.

• Journal of the Korean Applied Science and Technology
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• v.33 no.4
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• pp.762-770
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• 2016

The purpose of this study is to observe how Chrysanthemum Sibiricum Extract has anti-oxidant activity, cytotoxicity for skin cells, and anti-inflammatory and melanin inhibitory effects in order to find the development possibility of Chrysanthemum Sibiricum Extract as the ingredient of a functional cosmetic product. According to the analysis, Chrysanthemum Sibiricum Extract was found to have high contents of polyphenols and flavonoids and excellent DPPH radical scavenging activity. The extract had no significant cytotoxicity for Raw 264.7 cell and B16F10 cell and significantly inhibited the creation of NO induced LPS in Raw 264.7 cell so as to present anti-inflammatory effect. In B16F10 cell, melanin creation was induced with ${\alpha}$-MSH, and then melanin biosynthesis inhibition was measured. As a result, melanin creation was inhibited in the concentration dependence way. Given the results, it is considered that Chrysanthemum Sibiricum Extract is applicable as the ingredient of a functional cosmetic product that has low cytotoxicity for skin cells, high anti-oxidant activity, anti-inflammatory effect, and whitening effect.

• Journal of the East Asian Society of Dietary Life
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• v.12 no.5
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• pp.364-369
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• 2002

Mulberry leaves are believed to be a potent inhibitor of intestinal $\alpha$-glycosidase and the digestion of sucrose in the small intestine. Mulberry leaves are also blown to help prevent the postprandial hyperglycemia. The objective of this study was to elucidate the functionality and anti-hyperglycemic effect of mulberry leaves, and to develop a functional drink using mulberry leaf, silk peptide and oriental medicine. Several mixtures of mulberry lear extract silk peptide and oriental medicine were made for the purpose of manufacture and formulation of products. These mixtures were tested to check the $\alpha$-glycosidase inhibition effect to find the best formula. The optimum conditions for a mulberry leaf hot water extract were that the size of leaf was under 3mm, the amount of leaf needed 50~100 g/L, extraction temperature 9$0^{\circ}C$ and extraction time 2 hr. The yield of extraction was 20~25%. The anti-hyperglycemic effect of mulberry leaves was at maximum when the concentrations of mulberry leaf extract and silk peptide were 1% and 0.1%, respectively.

• Korean Journal of Pharmacognosy
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• v.52 no.3
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• pp.192-201
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• 2021

Dangguisu-san (DGSS) is widely known traditional herbal medicinal formula in Korea for treatment of traumatic injury by traffic accident, ecchymosis, abdominal distension and anti-thrombosis of blood. This study was conducted to develop the simultaneous analyze method using high performance liquid chromatography (HPLC) and examine the effect of anti-inflammatory activity of DGSS-dry extract (DGSS-DE) and DGSS-mix extract powder (DGSS-MEP). Physicochemical characteristics of DGSS-DE and DGSS-MEP showed that there is no significant difference in pH, titratable acidity, total soluble solid content and browning degree except for color value (L, a, b). 15 functional constituents of DGSS were identified and the correlation coefficient values of DGSS-DE and DGSS-MEP were conformed 0.950. Also, DGSS-DE and DGSS-MEP significantly decreased the secretion of nitric oxide (NO), prostaglandin E₂ (PGE₂), interleukin-1β (IL-1β), interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) through inhibited expression of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), IL-1β, IL-6, and TNF-α. From these result, DGSS-MEP showed similar chemical composition and anti-inflammatory effect to DGSS-DE. Therefore, DGSS-DE and DGSS-MEP may be useful as potential source of drug to prevent inflammation.

• PNF and Movement
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• v.18 no.3
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• pp.453-463
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• 2020

Purpose: This study aimed to investigate the effect of an intensively rehabilitation program on the gait, balance, functional performance, and wearing satisfaction of patients with traumatic lower extremity amputations caused by industrial accidents. Methods: In this study, the anonymized electronic medical records of individuals who participated in the intensive rehabilitation program (among those who were admitted to the hospital belonging to the Labor Welfare Corporation) due to an industrial accident from August 2018 to September 2019 were collected. As a result, the records of 12 subjects meeting the screening criteria were analyzed. Results: According to the time of application to the intensive rehabilitation program, the 10 Meter Walk Test (10MWT) (p < 0.01), Berg Balance Scale (BBS) (p < 0.01), Timed Up and Go Test (TUG) (p = 0.01), the L Test of Functional Mobility (L-test) (p < 0.01), Prosthetic Limb Users Survey of Mobility (Plus-M) (p < 0.01), and Houghton Score Question (HSQ) (p < 0.01) values significantly improved with time. Conclusion: This study confirmed the positive effect of an intensive rehabilitation program on the gait, balance, functional performance, and wearing satisfaction of patients with traumatic lower extremity amputations caused by industrial accidents. However, this study was limited by the absence of a control group, and, thus, it highlights the need for more extensive research with a large sample.