• 공업화학
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• 제30권5호
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• pp.513-522
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• 2019

유기물질, 전이금속 및 유기-금속 구조체(MOFs)를 기반으로 하는 촉매들이 유기인 계열 독성물질들을 분해하고 제거하는데 효과적임이 보고되어 왔다. 최근 20년간 독성물질 분해연구를 위해 다공성 MOFs들이 응용 목적에 맞게 디자인되고 합성되었다. $Zr_6$ 기반의 금속노드와 유기결합체를 가지는 MOFs들은 세공크기, 공극률, 표면적, Lewis acidic 자리 그리고 열적 안정성 등과 같은 기본구조내의 변형이 가능하기 때문에 화학작용제, 살충제 및 제초제를 제거하는 촉매로 널리 사용되어왔다. 본 리뷰에서는 구조, 안정성, 입자크기, 연결된 리간드 수, 유기 기능기 등에 따른 MOFs들의 촉매효율과의 연관성을 다루게 될 것이다.

• 생약학회지
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• 제49권4호
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• pp.341-348
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• 2018

This study was carried out to obtain the basic informations for phenolic compounds by various sections of Acanthopanacis Caulis. The phenolic compounds of Korean Acanthopanacis bark and lignum (Acanthopanax divaricatus var. albeofructus, Acanthopanax koreanum) were measured by the HPLC analysis. The content of total phenolic components of Acanthopanax koreanum bark (1.532%) was about 9.9 times higher than that of Acanthopanax koreanum lignum (0.155%). And also, The content of total phenolic components of Acanthopanax divaricatus var. albeofructus bark (0.420%) was about 2.8 times higher than that of Acanthopanax divaricatus var. albeofructus lignum (0.149%). Eleutheroside E, a functional ingredient of Acanthopanacis Caulis, showed 3.6 times higher contents of Acanthopanax koreanum bark (0.144%) than Acanthopanax koreanum lignum (0.040%). In the case of Acanthopanax divaricatus var. albeofructus bark (0.129%), the content of the eleutheroside E was 1.7 times higher than that of the Acanthopanax divaricatus var. albeofructus lignum (0.074%).

• Journal of Applied Biological Chemistry
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• 제65권3호
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• pp.153-158
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• 2022

This study aimed to identify the phytochemical constituents of Lactuca serriola leaves and perform quantitative analysis of the methanol (MeOH) extract of L. serriola, L. indica, L. raddeana, L. sativa, and L. triangulata. Six compounds were isolated from the MeOH extracts of L. serriola using open column chromatography and identified as protocatechuic acid (1), caffeic acid (2), cynaroside (3), apigenin 7-glucuronide (4), luteolin (5), and apigenin (6) using ¹H-, ¹³C-nuclear magnetic resonance, and mass spectrometry. Quantitative analysis of the six compounds was performed on the MeOH extract of Lactuca species using high-performance liquid chromatography (HPLC) and an ultraviolet (UV). A reverse-phased column was used, and the UV absorbance was set to 280 nm. The contents of compounds 2 and 3 were the highest (1.58 and 2.64 mg/g ext., respectively) in L. serriola extracts. However, compounds 4 and 6 were higher (1.46 and 0.40 mg/g ext., respectively) in L. triangulata. These results provide quantitative data for the application of Lactuca species in the pharmaceutical and functional food industries.

• Journal of Applied Biological Chemistry
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• 제66권
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• pp.338-344
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• 2023

Curcuma longa is a plant belonging to the genus Curcuma and is distributed across various Asian regions. This plant is widely known for its rhizomes, which possess a variety of pharmacological properties. However, although the leaves and stems of this plant also contain several health-promoting secondary metabolites, very few studies have characterized these compounds. Therefore, our study sought to quantify the secondary metabolites from the leaves and stems of Curcuma longa L. (LSCL) using liquid chromatography-electrospray ionization-mass spectrometry (LC-ESI-MS) and high-performance liquid chromatography (HPLC). Our LC-ESI-MS analyses detected twenty-one phenolic compounds in the LSCL, among which fifteen compounds were detected via HPLC analysis. Four compounds, namely vanillic acid (0.129 mg/g), p-coumaric acid (0.431 mg/g), 4-methylcatechol (0.199 mg/g), and afzelin (0.074 mg/g) were then quantified. These findings suggest that LSCL is rich in secondary metabolites and holds potential as a valuable resource for the development of functional and nutritional supplements in the future.

• Bulletin of the Korean Chemical Society
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• 제27권9호
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• pp.1364-1370
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• 2006

New liquid-crystalline biphenyl carboxylates with an achiral swallow-tail derived from 1,3-dialkoxy-2-propanol $[(ROCH_2)_2CHOH$] where R is methyl, ethyl, propyl, butyl, $CH_2CF_3$, and $CH_2CF_2CF_3$ were prepared. These achiral liquid crystals having 1,3-dialkoxy-2-propyl moieties exhibit diverse phase sequences [I-SmA-(SmC)-(SmCalt)-Cr] depending on the substituent R group of the swallow-tail. The compounds carrying a fluorinated swallow-tail exhibit antiferroelectric-like smectic C phases, and their temperature ranges are broader than the corresponding non-fluorinated swallow-tailed ones.

• Rapid Communication in Photoscience
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• 제1권1호
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• pp.17-18
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• 2012

Photoaddition reactions between 1,2-dicarbonyl compounds and silyl enol ethers in acetonitrile and benzene were explored. Irradiation of acetonitrile or benzene solutions containing 1,2-diketone, acenaphthalquinone, phenanthrene-quinone and silyl enol ethers is observed to promote the production of 1,4-dioxenes, oxetanes, and ${\beta}$-hydroxyketone by the [4+2]-cycloadditon, Paterno-Buchi processes, and SET promoted Claisen-type condensation. Among these competitive pathways leading to the generation of each types of products, SET promoted 1,4-dioxene and ${\beta}$-hydroxyketone formation are more favored regardless of solvent polarity.

• Preventive Nutrition and Food Science
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• 제16권4호
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• pp.370-375
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• 2011

The antioxidative activity and the polyphenolic composition were examined in four different cultivars of apple (Malus domestica), 'Fuji', 'Tsugaru', 'Hongro' and 'Kogetsu', and their parts (peel, core, pulp and juice). The total phenolics, flavonoids and anthocyanins differed among the tested cultivars and parts. Peel parts had the highest total phenolics and anthocyanin content. Contributions of those phenolics to total antioxidative activity were determined using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging assays, and the linoleic acid oxidation assay. Concentration of phenolics contributes significantly to the total antioxidative activity of apples. Clearly, apple peels, especially from Hongros and Kogetsus, possess high levels of phenolic compounds and antioxidants. Therefore, apple peels may potentially function as a value-added ingredient.

• Bulletin of the Korean Chemical Society
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• 제29권5호
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• pp.963-968
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• 2008

For the [$Cr_2(H_2tmp)_2Cl_4$] compound, simplified models with two bridging methoxo ligands have been studied. The influence of the bridging Cr-O-Cr bond angles on the exchange coupling between metal atoms in the model compound has been analyzed by means of density functional calculations with the broken-symmetry approach. Coupling constant calculated for the full structure is in good agreement with the experimentally reported value, confirming the validity of the computational strategy used in this work to predict the exchange coupling in a family of related dinuclear Cr(III) compounds. The calculations indicate a good correlation between the calculated coupling constant and the sum of the squared energy gap of three pairs of metal $t_{2g}$ OMSOs with a limited variation of the Cr-O-Cr angle. The spin density distribution and the mechanism of magnetic coupling interactions are discussed.

• 대한약학회:학술대회논문집
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• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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• pp.179.1-179.1
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• 2003

Chiral building blocks have the importance in the pharmaceutical and agrochemical industries as well as in the development of rapid and efficient syntheses of bioactive compounds and natural product. Vinylstannane contains two synthetically useful functional groups (vinylstannane and allylic alcohol). The vinylstannane functional group can be used in C-C bond formation under a variety of conditions and the allylic alcohol functional can be used in hydroxyl-directed epoxidations, cyclopropanations, and sigmatropic rearrangements. (omitted)

• 한국식품위생안전성학회지
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• 제34권5호
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• pp.431-437
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• 2019

본 연구는 건강기능식품 프랑스해안송껍질추출물 중 catechin, caffeic acid, ferulic acid, taxifolin에 대한 동시분석법을 개발하는 연구이다. 최적분석조건을 확립하기 위해 시료 채취량, 용매 조건을 비교 검토하였으며, UPLC-MS/MS를 이용하여 각 4개 성분에 대한 정확한 분석 및 분석시간의 효율성도 향상하였다. 분석 시 사용한 컬럼은 Acquity UPLC BEH $C_{18}$이며, 정량이온으로 catechin, caffeic acid, ferulic acid, taxifolin 각각 133, 135, 245 및 248을 선정하였다. 확립된 시험법에 대해 특이성, 직선성, 검출한계, 정량한계, 정확성, 정밀성 등의 밸리데이션을 수행하였다. 4개 성분 모두 50-25000 mg/L 농도에서 결정계수(R2) 0.999이상으로 높은 직선성을 확인하였다. 또한 회수율은 84.9-104%이었고, 정밀성은 1.2-4.3%의 RSD를 확인하였다. 개발된 시험법은 프랑스해안송껍질추출물 중 catechin, caffeic acid, ferulic acid, taxifolin 분석을 위한 시험법으로 활용되기에 적합한 것으로 판단된다.