• Journal of Sensor Science and Technology
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• v.29 no.2
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• pp.100-104
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• 2020

Thus far, several in vivo biosensing platforms have been proposed to measure the mechanical contractility of cultured cardiomyocytes. However, the low sensitivity and screening rate of the developed sensors severely limit their practical applications. In addition, intensive research and development in cardiovascular disease demand a high-throughput drug-screening platform based on biomimetic engineering. To overcome the drawbacks of the current state-of-the-art methods, we propose a high-throughput drug-screening platform based on 16 functional high-sensitivity well plates. The proposed system simulates the physiological accuracy of the heart function in an in vitro environment. We fabricated 64 cantilevers using highly flexible and optically transparent silicone rubber and placed in 16 independent wells. Nanogrooves were imprinted on the surface of the cantilever to promote cell alignment and maturation. The adverse effects of the cardiovascular drugs on the cultured cardiomyocytes were systematically investigated. The 64 cantilevers demonstrated a highly reliable and reproducible mechanical contractility of the drug-treated cardiomyocytes. Real-time high-throughput screening and simultaneous evaluation of the cardiomyocyte mechanical contractility under multiple drugs verified that the proposed system could be used as an efficient drugtoxicity test platform.

• Elastomers and Composites
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• v.56 no.1
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• pp.6-11
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• 2021

In order to develop an ultra-high-density elastomeric material for substitution of steel dynamic dampers, a new curing system and technique for high-loading of the filler were examined in this study. Mechanochemical modification of chloroprene rubber (MAH-g-CR) using an internal mixer was carried out with maleic anhydride (MAH) as a reactive monomer. The optimum amount of MAH was 10 phr and the efficient grafting of MAH on CR could be achieved at a mixing temperature of 100℃. After preparing MAH-g-CR, 50 mol% epoxidized natural rubber (ENR 50) was blended with MAH-g-CR to develop a "self-curable rubber blend system" via reaction between the functional groups of the elastomeric matrices without the curing agent and additives. The content of ENR 50 was fixed at 30 wt.% throughout evaluation of the curing behavior of the MAH-g-CR/ENR blend. Tungsten powder was added to the MAH-g-CR/ENR matrix up to 60 vol.% to obtain ultra-high-density, and the maximum density obtained was 7.57 g/㎤. Stable ts2 (scorch time) and t90 (90% cure time) could be obtained even when tungsten powder was incorporated up to 60 vol.%. In addition, the tensile strength and damping properties of MAH-g-CR/ENR containing 60 vol.% of tungsten were better than those of CR containing 60 vol.% of tungsten.

• ETRI Journal
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• v.37 no.4
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• pp.772-779
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• 2015

This paper presents a power-efficient hardware realization for a motion estimation technique that is based on the full-search block matching algorithm (FSBMA). The considered input is the quarter common intermediate format of digital video. The mean of absolute difference (MAD) is the distortion criteria employed for the block matching process. The conventional architecture considered for the hardware realization of FSBMA is that of the shift register-based 2-D systolic array. For this architecture, a conservative approximation technique is adapted to eliminate unnecessary MAD computations involved in the block matching process. Upon introducing the technique to the conventional architecture, the power and complexity of its implantation is reduced, while the accuracy of the motion vector extracted from the block matching process is preserved. The proposed architecture is verified for its functional specifications. A performance evaluation of the proposed architecture is carried out using parameters such as power, area, operating frequency, and efficiency.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2007.11a
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• pp.107-112
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• 2007

The rise of the machine culture in the last 20th century has rapidly changed the world into a high-tech civilized society but at the same time, it also caused environmental estrangements such as damage in the environment and the loss of humanity in the human society due to materialism. As a reaction to the absence of humanity in such environment, in these modern days design which acts as the product of public art, escaped from the previous physical functional satisfaction and stood out as the culture industry that satisfies human's sensibility. This study is focusing on the method of how such sensitive designs are expressed in the interior space of retail shops and such methods are researched through the image evaluation test conducted to the 10 brands of overseas' jewelery shops. The purpose of this study is to analyze the meaning and effects of designs that took consideration of sensibility in a retail shop and to establish efficient marketing strategy using sensitive design and to utilize it into the interior space.

• Journal of the Korean Institute of Educational Facilities
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• v.11 no.5
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• pp.14-23
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• 2004

Building-integrated photovoltaic(BIPV) systems can operate as a multi-functional building components, which generates electricity and serves as part of building envelope. It can be regarded as a new architectural elements, adding to the building's aesthetics. Besides of these benefits, the application of PV systems into school buildings tends to play an important role in energy education to students. In this context, this study aims to analyse the applicability of PV systems into school buildings. For an existing school building, four types of BIPV designs were developed; rooftops, wall-attached, wall-mounted with angle, and sunshading device. Based on energy modeling of those BIPV systems, the whole 60.1kWp rated PV installation is expected to yield about 65.6MWh of electricity, that is about 50% more than the annual electricity consumption of the school, 44MWh. It was also found that the applicability of the PV systems into the school building was very high, and the rooftop systems with the optimized angle was the most efficient in energy production, followed by sunshading, wall-mounted with angle and wall-attached. It concludes that school buildings have a reasonable potential to apply PV systems in the aspects of building elements and electricity production.

• Food Science and Preservation
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• v.24 no.5
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• pp.673-679
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• 2017

In this study, the antimicrobial, antioxidant activities and ${\alpha}$-glucosidase inhibitory activities of Amphidinium carterae ethanol extract (AE) was evaluated for using as a functional food ingredient. Chlorella ethanol extract (CE) was used to the comparison as a control. Anticancer activities of the AE and CE were analyzed by HepG2 and HT-29 human cancer cell. The AE showed antimicrobial activities for all tested bacterial strains. Whereas, CE showed antimicrobial activities for several tested bacterial strains only. The CE showed higher total phenolics contents, DPPH and ABTS radical-scavenging activities (47.36 mg/g, 22.42% and 28.58%, respectively) than those of AE (8.88 mg/g, 20.16% and 17.69%, respectively). AE showed anti-diabetic effect on ${\alpha}$-glucosidase inhibitory activity with dose-dependantly manner. The cell viability of AE ($125{\mu}g/mL$) on HepG2 and HT-29 human cancer cells were 38.12% and 11.27%, respectively. It was demonstrated that ethanol was efficient solvent for extracting functional components from A. carterae. These results indicated that AE can be described as a good candidate for using as a functional food ingredient.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2003.10a
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• pp.369-372
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• 2003

This paper describes a design of OFDM (Orthogoanl Frequency Division Multiplexing) based wireless LAN system receiver, defined in IEEE 802.11a standards. Because OFDM system uses several orthogonal sequence sets, it ran avoid selective fading of fast data transfer problem when it is used with error correction code. But if the receiver is not synchronized, the orthogonal of between sub-ralliers will be destroyed and the data interruption will be generated. So it makes error property get worse very murk. For improving the noise error, we use the relationship of phasor between sub-carriers and make system synchronization using one tab equalizer. The designed OFDM block is described by Verilog HDL for the efficient and small size hardware. And we preform the functional verification and evaluation using the vector of standards.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.18 no.1
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• pp.59-67
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• 2009

The purpose of this study is to provide a decision support to select an appropriate layered manufacturing(LM) machine that suits the application of a part. Selection factors include concept model, form/fit/functional model, pattern model far molding, material property, build time and part cost that greatly affect the performance of LM machines. However, the selection of a LM is not an easy decision because they are uncertain and vague. For this reason, the aim of this research is to propose hybrid multiple attribute decision making approaches to effectively evaluate LM machines. In addition, because subjective considerations are relevant to selection decision, a fuzzy logic approach is adopted. The proposed selection procedure consists of several steps. First, we identify LM machines that the users consider After constructing the evaluation criteria, we calculate the weights of the criteria by applying the fuzzy Analytic Hierarchy Process(AHP) method. Finally, we construct the fuzzy Technique of Order Preference by Similarity to Ideal Solution(TOPSIS) method to achieve the ranking order of all machines providing the decision information for the selection of LM machines.

• PNF and Movement
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• v.15 no.1
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• pp.77-84
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• 2017

Purpose: This study aimed to investigate the effect of visual feedback training-for gradual weight shift in sit-to-stand training-on the balance and walking abilities of chronic hemiplegia patients. Methods: Twenty patients with chronic hemiplegia volunteered to participate in this study. The experimental group received visual feedback for gradual weight shift in the sit-to-stand training, while the contrast group followed the standard process for the sit-to-stand training. The evaluation of the balance and walking ability was conducted with the functional reach test (FRT), Berg balance scale (BBS), five time sit-to-stand (FTSTS) test, timed up and go (TUG) test, 10 m walk test (10MWT), balancia, activities-specific balance confidence (ABC) scale, and falls efficacy scale (FES). Results: In the results before and after intervention, there was a significant difference in TUG, 10MWT, ABC, and FES in the visual feedback training group (p < 0.05). In the control group, there was a significant difference in the 10MWT and ABC (p < 0.05). Also, in the evaluation of the postural fluctuations, the control group data showed a significant increase in Covar. The visual feedback group showed a significant difference in the W average. Conclusion: The visual feedback training group showed some improvement in terms balance and walking ability and on the ABC scale and FES. Therefore, if the diagonal progressive weight bearing exercise is combined with the various patterns and basic principles of PNF, it may be a more efficient intervention method.

• Archives of design research
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• v.11 no.2
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• pp.117-126
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• 1998

The underground space which has been highlighted anew in view of urban scenery and environmental conservation through the control of ground development and solution of urban problems through making the utility of urban space efficient can promote the urban service, amenity, stability and others by arranging the urban function of ground area to the underground which is anticipated to be demanding the more in the future an also can be effective measures of confrontation in the solution of traffic, the complex in the heart of the city and lack of land through effective construction of the structure of urban space. But it has been understood to be extremely negative space at this time as limited to negative and fragmentary development and it has faced the necessity of constructing pleasant environment by overcoming every problem. After all, through the general research of underground space, this dissertation is reconsidering the development value of environmental design on the basis of the case study in international city development of underground space, and trying to extract design factors which should be treated in developing the underground space by establishing the evaluation model on the functional, techinical and behavioral elements factors.