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Structure Analysis of the Full Length PDI Genomic DNA Isolated from Bombyx mori

  • Kim, Sung-Wan;Goo, Tae-Won;Yun, Eun-Young;Park, Kwang-Ho;Hwang, Jae-Sam;Kang, Seok-Woo;Kwon, O-Yu
    • Proceedings of the Korean Society of Sericultural Science Conference
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    • 2003.04a
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    • pp.44-44
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    • 2003
  • Protein disulfide isomerase (PDI) is not only an isomerase catalyzing the formation of native disulfide bond(s) of nascent peptide, but also a molecular chaperone assisting chain folding. We have already reported the structure of a cDNA (bPDl) encoding PDI from Bombyx mori and the function of PDI as foldase in assisting protein folding. (omitted)

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A Study on the Major Building Material and Construction Method Influencing to IAQ through Full-Scale House Construction (실물 주거 시공을 통한 실내공기질에 영향을 미치는 주요 건축자재 및 시공방법에 관한 연구)

  • Yu Hyung-Ku;Park Jin-Chul;Rhee Eon-Ku
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.18 no.3
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    • pp.262-269
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    • 2006
  • Formaldehyde and total volatile organic compounds (TVOC) from building materials have been known as main causes of IAQ problem in Newly-Constructed Multi-Family Houses. Because Multi-Family Houses are built in large quantities in a similar manner, inappropriate selection of building materials and method will detrimental affect IAQ. This research aims to identify major causes of Indoor Air Pollutants in Multi-Family Houses, by constructing Mock-Up & One-Room House. As a result, self leveling concrete, door, and furniture construction is a major cause of indoor formaldehyde increase, and tile bond is TVOC, and urethane water proof is Etylbenzene, and Xylene.

The Crystal Structure of Tolfenamic Acid $(C_{14}H_{12}ClNO_2)$, an Antiinflammatory Fenamate

  • Kim, Yang-Bae;Chung, Uoo-Tae;Park, Il-Yeong
    • Archives of Pharmacal Research
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    • v.19 no.2
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    • pp.160-162
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    • 1996
  • The structural analysis of tolfenamic acid, 2-[(3-chloro-2-methylphenyl)-amino]benzoic acid, was performed by single crystal X-ray diffraction technique. The compound was recrystallized from a mixture of ether and toluene in triclinic, space group $P2_1/c, \;with\; \partial=3.914(1), \; b=22.\; 020(2), \; c=14.271(1)\;{\AA}, \beta.=94.68(1)^{\circ}, $ and Z=4. The calculated density is $1.418 g/cm^3$. The structure was solved by the direct method and refined by full matrix least-squares procedure to the final R value of 0.039 for 1773 independent reflections. In the molecule, carboxyl group at the anthranilic acid is coplanar to the phenyl ring. The dihedral angle between the two aromatic rings of the molecule is $44.2^{\circ}$ The molecules are dirnerized through the intermolecular hydrogen bonds at the carboxyl group in the crystal.

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The Crystal and Molecular Structures of Sulfametrole

  • Koo Chung Hoe;Chung Yong Je;Shin Hyun So;Suh Jung Sun
    • Bulletin of the Korean Chemical Society
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    • v.3 no.1
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    • pp.9-13
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    • 1982
  • Sulfametrole, $C_9H_{10}N_4O_3S_2$, crystallizes in the monoclinic system, space group $P2_1/n$ , with a = 8.145(2), b = 16.505(4), c = 9.637(1)${\AA},{\beta}=103.72(1)^{\circ},D_m=1.52gcm^{-3}$,Z=4.Intensities for 3594(2143 observed) unique reflections were measured on a four-circle diffractometer with Mo $K{\alpha}$ radiation $({\lambda}=0.71069{\AA})$. The structure was solved by direct method and refined by full-matrix least squares to a final R of 0.070. The geometrical features of the thiadiazole ring indicate some ${pi}$-electron delocalization inside the ring. The least squares planes defined by the benzene and thiadiazole rings are nearly perpendicular to each other(dihedral angle; $93.9^{\circ}$ ). All the potential hydrogen-bond donor atoms in the molecule, N(1) and N(2), are included in the hydrogen bonding. The molecules through hydrogen bonding form three dimensional network.

The Crystal Structure of Metoclopramide

  • Shin, Whan-chul;Chang, Tai-Sik;Koo, Chung-Hoe
    • Bulletin of the Korean Chemical Society
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    • v.4 no.3
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    • pp.123-127
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    • 1983
  • The crystal structure of metoclopramide, $C_14H_22ClN_3O_2$, has been determined by X-ray diffraction techniques using diffractometer data obtained by the ${\omega}-2{\theta}$ scan technique with Mo $K\alpha$ radiation from a crystal with space group symmetry $P{\overline{1}}$ and unit cell parameters a = 7.500(1), b = 8.707(2), c = 13.292(2) ${\AA}$; ${\alpha}$ = 101.70(2), ${\beta}$ = 81.20(2), and ${\gamma}$ = $114.90(l)^{\circ}$. The sructure was solved by direct methods and refined by full-matrix least-squares to a final R = 0.055 for the 1524 observed reflections. The bent overall-conformation of the molecule seems to be determined mainly by the bifurcated intramolecular hydrogen bond from the amide nitrogen atom to the methoxy oxygen and the amine nitrogen atoms. The crystal packing consists of the hydrogen bonds, ${\pi}-{\pi}$ interaction and hydrophobic interaction.

Structural performance of recycled aggregates concrete sourced from low strength concrete

  • Goksu, Caglar;Saribas, Ilyas;Binbir, Ergun;Akkaya, Yilmaz;Ilki, Alper
    • Structural Engineering and Mechanics
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    • v.69 no.1
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    • pp.77-93
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    • 2019
  • Although much research has been carried out using recycled aggregates sourced from normal strength concrete, most of the buildings to be demolished are constructed with low strength concrete. Therefore, the properties of the concrete incorporating recycled aggregates, sourced from the waste of structural elements cast with low strength concrete, were investigated in this study. Four different concrete mixtures were designed incorporating natural and recycled aggregates with and without fly ash. The results of the mechanical and durability tests of the concrete mixtures are presented. Additionally, full-scale one-way reinforced concrete slabs were cast, using these concrete mixtures, and subjected to bending test. The feasibility of using conventional reinforced concrete theory for the slabs made with structural concrete incorporating recycled aggregates was investigated.

Crystal Structure of Antiinflammatory Sulindac

  • Koo Chung Hoe;Kim Sang Hern;Shin Wanchul
    • Bulletin of the Korean Chemical Society
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    • v.6 no.4
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    • pp.222-224
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    • 1985
  • The crystal structure of sulindac, $C_{20}H_{17}Fo_3S$, one of the nonsteroid antiinflammatory agents, has been determined by the X-ray diffraction techniques using diffractometer data obtained by the $\varpi-2{\theta}$ scan technique with Cu $$K_{\alpha}$$ radiation from a crystal with space group symmetry Pbca and unit cell parameters a = 8.166(1), b = 18.291(8), c = 23.245(10) ${\AA}.$ The structure was solved by direct methods and refined by full-matrix least-squares to a final R = 0.11 for the 1153 observed reflections. The carboxyl group is nearly perpendicular to the indenyl ring as observed in indomethacin. The dihedral angle between the indenyl and phenyl rings is $35^{\circ}while$ the corresponding angle in indomethacin is $67^{\circ}.$ Crystal packing consists of a hydrogen bond and partial ring stacking between the indenyl rings.

The Crystal and Molecular Structure of Chloramphenicol Base

  • Shin, Whan-Chul;Pyo, Myung_Ho
    • Bulletin of the Korean Chemical Society
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    • v.5 no.4
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    • pp.158-162
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    • 1984
  • The crystal structure of chloramphenicol base, $C_9H_{l2}N_2O_4$, the deacylated base of antibiotic chloramphenicol, has been determined by X-ray diffraction techniques using diffractometer data obtained by the ${\omega}-2{\theta}$ scan technique with CuK${\alpha}$ radiation from a crystal with space group symmetry $P2_12_12_1$ and unit cell parameters a = 22.322(6), b = 7.535(6), c = 5.781(5) ${\AA}$. The structure was solved by direct methods and refined by full-matrix least-squares to a final R = 0.051 for the 573 observed reflections. The overall conformation of the base is quite different from those of the chloramphenicol congeners which are similar despite the presence of many rotatable single bonds. The propane chain in the base is bent with respect to the phenyl ring, while it is extended in the chloramphenicol congeners. There is no intramolecular hydrogen bond between the hydroxyl groups of the propanediol moiety. All of the molecules in the crystal lattice are connected by a three-dimensional hydrogen bonding network.

Testbed of Power MOSFET Aging Including the Measurement of On-State Resistance (전력용 MOSFET의 온-상태 저항 측정 및 노화 시험 환경 구축)

  • Shin, Joonho;Shin, Jong-Won
    • The Transactions of the Korean Institute of Power Electronics
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    • v.27 no.3
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    • pp.206-213
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    • 2022
  • This paper presents setting up a laboratory-scale testbed to estimate the aging of power MOSFET devices and integrated power modules by measuring its on-state voltage and current. Based on the aging mechanisms of the component inside the power module (e.g., bond-wire, solder layer, and semiconductor chip), a system to measure the on-state resistance of device-under-test (DUT) is designed and experimented: a full-bridge circuit applies current stress to DUT, and a temperature chamber controls the ambient temperature of DUT during the aging test. The on-state resistance of SiC MOSFET measured by the proposed testbed was increased by 2.5%-3% after 44-hour of the aging test.

Flexural Behavior of Encased Composite Beams with Partial Shear Interaction (매립형 불완전 합성보의 휨 거동 예측)

  • Heo, Byung Wook;Bae, Kyu Woong;Moon, Tae Sup
    • Journal of Korean Society of Steel Construction
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    • v.16 no.6 s.73
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    • pp.747-757
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    • 2004
  • With steel and concrete composite beams, the incomplete interaction between the steel and the concrete slab leads to an appreciable increase in beam deflections. Moreover, encased composite beams using a deep deck plate or hollow-core PC slabs are critical to deflection due to their inherent geometry. In this paper, by using the calculation tools that were developed for a previous study on the deflection of encased composite beams considering the slip effects and load-slip curve, the shear bond stress and additional deflection induced due to interface slip of the encased composite beam are presented. It was found that the slip effects significantly contribute to the encased composite beam deflections and result in stiffness reduction of up to 30% compared to that of full shear interaction beams. The predicted results were compared with the measurement of 18 specimens tested in this study, and comparisons show a high degree of accuracy, within 6%.