• Title/Summary/Keyword: frontier park

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Analysis of Discriminant Accuracy of Estimated Load Carrying Capacity in Bridges (교량 추정 내하율 판별 정확도 분석)

  • Kyu San Jung;Dong Woo Seo;Byeong Cheol Kim;Gun Soo Kim;Ki Tae Park;Woo Jong Kim
    • Journal of Korean Society of Disaster and Security
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    • v.16 no.4
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    • pp.123-128
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    • 2023
  • This paper presents the results of an analysis of the discrimination accuracy of a bridge load carrying capacity estimation model based on data from inspection reports. The load carrying rate estimation model was derived using statistical methods through the collection of 2,161 inspection reports. By entering the bridge specifications and maintenance information, you can check the estimated load carrying capacity of the bridge. In order to verify the discrimination accuracy of the estimated load carrying rate model, the estimated load carrying rate was compared with the load carrying rate in the inspection and diagnosis report for 164 public bridges for which data was available. Although there are differences depending on the bridge type, the results were obtained with an accuracy of over 80% in determining the estimated load carrying capacity.

Developing Food List for Risk Assessment of Contaminants in Korean Foods (식품으로부터의 오염물질 섭취량 및 위해도 평가를 위한 대표식품 선정)

  • Lee, Haeng-Shin;Kim, Bok-Hee;Jang, Young-Ai;Park, Seon-Oh;Oh, Chang-Hwan;Kim, Ji-Young;Kim, Hee-Yun;Chung, So-Young;Sho, Yoo-Sub;Suh, Jung-Hyuck;Lee, Eun-Ju;Kim, Cho-Il
    • Korean Journal of Food Science and Technology
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    • v.37 no.4
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    • pp.660-670
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    • 2005
  • Standard procedure for development of food list was established based on food intake data of 2001 National Health and Nutrition Survey and 2002 Seasonal Nutrition Survey for Total Diet Study. Foods were sorted in descending order of mean intake, and 54 items within cumulative percentage of 80 were selected, followed by selection of 16 additional items with consumption frequency of 10% or higher. Based on higher consumption in certain seasons, regions, sexes, and age classes, 14 additional items were added. Additional 17 items with probable high contents of heavy metals or 23 items with probable high pesticide residues were added. Altogether, 101 and 107 individual food items were included for heavy metal and pesticide residue lists, accounting for 84.9 and 83.3% mean energy intakes of Korean population, respectively.

Genetic diversity and relationships of Korean, Japanese, and Chinese Jilin provincial wild soybeans (Glycine soja Sieb. and Zucc.) based on SSR markers (한국, 일본 및 중국 지린성 야생콩(Glycine soja Sieb. and Zucc.)의 SSR마커에 의한 유전적 다양성과 유연관계)

  • Jang, Seong-Jin;Park, Su-Jeong;Piao, Xiang-Min;Song, Hang-Lin;Hwang, Tae-Young;Cho, Yong-Gu;Liu, Xian-Hu;Woo, Sun-Hee;Kang, Jung-Hoon;Kim, Hong-Sig
    • Korean Journal of Breeding Science
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    • v.42 no.1
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    • pp.87-99
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    • 2010
  • Genetic diversity and relationships within and among Korean, Japanese and Chinese Jilin provincial wild soybeans based on SSR markers were evaluated to enlarge genetic variation in soybean breeding in the future. A total of 184 wild soybeans including 67 Korean, 71 Japanese and 46 Chinese Jilin provincial wild soybeans were analyzed to evaluate genetic diversity and relationships based on 23 SSR markers. Korean and Japanese wild soybeans were obtained from National Agrobiodiversity Center, Korea, and Biological Resource Center in Lotus and Glycine, Frontier Science Research Center, University of Miyazaki, Japan, respectively. Chinese wild soybeans were collected from Jilin province, China. Twenty three SSR markers generated a total of 964 alleles with an average of 41.9 alleles per marker. Number of alleles ranged from 23 (Satt635) to 56 (Satt157). Genetic diversity (PIC value) of 184 wild soybeans ranged from 0.880 to 0.968 with an average of 0.945. Number of alleles for Korean, Japanese and Chinese Jilin provincial wild soybeans was 513 with an average of 22.3, 511 with an average of 22.2, and 312 with an average of 13.6 per marker, respectively. PIC value for Korean, Japanese and Chinese Jilin provincial wild soybeans was similar with an average of 0.905, 0.897, and 0.850, respectively. Cluster analysis based on genetic distances estimated by SSR markers classified wild soybeans into 3 clusters. Cluster I included only Chinese Jilin provincial wild soybeans. Cluster II included most of Japanese wild soybeans including 5 Korean wild soybeans. Cluster III included most of Korean wild soybeans including 6 Japanese and 1 Chinese Jilin provincial wild soybeans. Cluster I was not subclassified, but cluster II and III were subclassified into various groups. Genetic distance evaluated by SSR markers between Korean and Japanese wild soybeans was closer than that of between Korean and Chinese Jilin provincial, and between Japanese and Chinese Jilin provincial wild soybeans.

Investigation of Structural and Optical Characteristics of In2Se3 Thin Films Fabricated by Thermal Annealing (열처리로 제조된 In2Se3 박막의 구조 및 광학적 특성 연구)

  • Park, Jae-Hyoug;Kim, Dae-Young;Park, Gwang-Hun;Han, Myung-Soo;Kim, Hyo-Jin;Shin, Jae-Cheol;Ha, Jun-Seok;Kim, Kwang-Bok;Ko, Hang-Ju
    • Journal of the Korean Vacuum Society
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    • v.21 no.3
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    • pp.136-141
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    • 2012
  • We report investigation of structural and optical characteristics of $In_2Se_3$ thin films fabricated by thermal annealing process. Indium (In) is deposited on substrates by sputtering methods and $In_2Se_3$ thin films are fabricated by thermal annealing it with selenium vapor. The annealing temperature was changed from $150^{\circ}C$ to $400^{\circ}C$. We observe formation and phase changes of $In_2Se_3$ thin films with increase of annealing temperature. Conglomeration of In is observed at low annealing temperature (${\leq}150^{\circ}C$). $In_2Se_3$ phases are started to form at $200^{\circ}C$ and ${\gamma}-In_2Se_3$ phase form at $350^{\circ}C$. High-quality ${\gamma}-In_2Se_3$ thin film with wurtzite structure is obtained at $400^{\circ}C$ of annealing temperature. Furthermore, we confirm that band gaps of $In_2Se_3$ thin films are increased according to increase of annealing temperature. Optical band gap of high-quality ${\gamma}-In_2Se_3$ is found to be 1.796eV.

The Mitochondrial Warburg Effect: A Cancer Enigma

  • Kim, Hans H.;Joo, Hyun;Kim, Tae-Ho;Kim, Eui-Yong;Park, Seok-Ju;Park, Ji-Kyoung;Kim, Han-Jip
    • Interdisciplinary Bio Central
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    • v.1 no.2
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    • pp.7.1-7.7
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    • 2009
  • "To be, or not to be?" This question is not only Hamlet's agony but also the dilemma of mitochondria in a cancer cell. Cancer cells have a high glycolysis rate even in the presence of oxygen. This feature of cancer cells is known as the Warburg effect, named for the first scientist to observe it, Otto Warburg, who assumed that because of mitochondrial malfunction, cancer cells had to depend on anaerobic glycolysis to generate ATP. It was demonstrated, however, that cancer cells with intact mitochondria also showed evidence of the Warburg effect. Thus, an alternative explanation was proposed: the Warburg effect helps cancer cells harness additional ATP to meet the high energy demand required for their extraordinary growth while providing a basic building block of metabolites for their proliferation. A third view suggests that the Warburg effect is a defense mechanism, protecting cancer cells from the higher than usual oxidative environment in which they survive. Interestingly, the latter view does not conflict with the high-energy production view, as increased glucose metabolism enables cancer cells to produce larger amounts of both antioxidants to fight oxidative stress and ATP and metabolites for growth. The combination of these two different hypotheses may explain the Warburg effect, but critical questions at the mechanistic level remain to be explored. Cancer shows complex and multi-faceted behaviors. Previously, there has been no overall plan or systematic approach to integrate and interpret the complex signaling in cancer cells. A new paradigm of collaboration and a well-designed systemic approach will supply answers to fill the gaps in current cancer knowledge and will accelerate the discovery of the connections behind the Warburg mystery. An integrated understanding of cancer complexity and tumorigenesis is necessary to expand the frontiers of cancer cell biology.

Cellular Responses to Alcohol in Escherichia coli, Clostridium acetobutylicum, and Saccharomyces cerevisiae (알코올에 대한 Escherichia coli, Clostridium acetobutylicum, Saccharomyces cerevisiae의 반응)

  • Park, Ju-Yong;Hong, Chun-Sang;Han, Ji-Hye;Kang, Hyun-Woo;Chung, Bong-Woo;Choi, Gi-Wook;Min, Ji-Ho
    • Korean Chemical Engineering Research
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    • v.49 no.1
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    • pp.105-108
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    • 2011
  • The increased concern for the security of the oil supply and the negative impact of fossil fuels on the environment, particularly greenhouse gas emissions, has put pressure on society to find renewable fuel alternatives. Compared to the traditional biofuel, ethanol, higher alcohols offer advantage as gasoline substitutes because of their higher energy density and lower hygroscopicity. For this reason, microbial fermentation is known as potential producers for sustainable energy carriers. In this study, bacterial responses including cellular and molecular toxicity were studied in three different microorganisms, such as Escherichia coli, Clostridium acetobutylicum, and Saccharomyces cerevisiae. In this study, it was analyzed specific stress responses caused by ethanol and buthanol using four different stress responsive genes, i.e. fabA, grpE, katG and recA. The expression levels of these genes were quantified by semi-quantitative reverse transcription-PCR. It was found that four genes have shown different responsive patterns when E. coli cultures were under stressful conditions caused by ethanol and buthanol, respectively. Therefore, in this study, the stress responsive effects caused by these alcohols and the extent of each stress response can be analyzed using the expression levels and patterns of different stress responsive genes.

Low Dose Exposure to Di-2-Ethylhexylphthalate in Juvenile Rats Alters the Expression of Genes Related with Thyroid Hormone Regulation

  • Kim, Minjeong;Jeong, Ji Seong;Kim, Hyunji;Hwang, Seungwoo;Park, Il-Hyun;Lee, Byung-Chul;Yoon, Sung Il;Jee, Sun Ha;Nam, Ki Taek;Lim, Kyung-Min
    • Biomolecules & Therapeutics
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    • v.26 no.5
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    • pp.512-519
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    • 2018
  • Phthalates widely used in the manufacture of plastics have deeply penetrated into our everyday lives. Recently, a concern over the toxicity of phthalates on thyroid, has been raised but in most of cases, the doses employed were unrealistically high. To investigate the effects of phthalates on thyroid, we investigated the effects of the repeated oral exposure to low to high doses (0.3, 3, 30 and 150 mg/kg) di-2-ethylhexylphthalate (DEHP) from weaning to maturity for 90 days in juvenile rats on the thyroid. The histological examination revealed that DEHP significantly induced hyperplasia in the thyroid from the doses of 30 mg/kg, which was confirmed with Ki67 staining. In line with this finding, increased mRNA expression of thyrotropin releasing hormone (Trh) was observed in the thyroid of female at 0.3 mg/kg and 150 mg/kg as determined by RNAseq analysis. Moreover, significantly increased expression of parathyroid hormone (Pth) in the female at 0.3 mg/kg, and thyroglobulin (Tg) and thyroid hormone responsive (Thrsp) in the male at 0.3 mg/kg were noted in the blood, of which changes were substantially attenuated at 150 m/kg, alluding the meaningful effects of low dose DEHP on the thyroid hormone regulation. Urinary excretion of mono-2-ethylhexyl-phthalate (MEHP), a major metabolite of DEHP was determined to be 4.10 and 12.26 ppb in male, 6.65 and 324 ppb in female at 0.3 and 30 mg/kg DEHP, respectively, which fell within reported human urine levels. Collectively, these results suggest a potential adverse effects of low dose phthalates on the thyroid.

The Productivity Analysis on Regional Logistics Warehouse (지역별 물류창고의 생산성 분석)

  • Park, Hong-Gyun
    • Journal of Korea Port Economic Association
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    • v.28 no.1
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    • pp.143-157
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    • 2012
  • By strengthening the market control and expanding the networks, providers of global logistics are expanding their service scope. The warehouses connect networks to internal and external warehouses by using logistics providers. The paper focuses on analyzing the efficiency of warehouses on each district. Therefore, the study classifies the factors which specify the efficiency of a total logistics of warehouse industry and warehouses' employees and the number of warehouses on district. Furthermore, the most recently published reports by National Center for Statistics in 2012 was used in order to guarantee credibility of the study. This study utilizes five years of materials, which are from 2005 to 2009. By applying SBM (Slack Based Measure), DEA Window model, and the Malmquist productivity model, the trend in efficiency and stableness were analyzed. The principal purpose of the paper is evaluating the efficiency. Also, analyzing its determinants and illustrating a long-term relationship between the regional warehouses and annual turnover of the warehouses were used as output measures. In addition, the number of warehouses of each region, employees, warehouses equipments, and the Logistics Warehouses Providers were used as input measurements. As a result, Malmquist productivity model and annual stableness has shown a continuous increasing. Ultimately, to be approved as product of Korea, a new stratiges that meet the standards and Rules of Origins by FTA should be developed. Therefore, there must be a development that takes regional characteristics into consideration.

Molecular Orbital Theoretical Study on the Conformation and Chemical Reactivity of Insecticidal 0,0-Diethylphenylphosphate Derivatives (살충성(殺蟲性) 0,0-Diethylphenylphosphate 유도체(誘導體)의 형태(形態)와 반응성(反應性)에 관(關)한 분자궤도론적(分子軌度論的) 연구(硏究))

  • Park, Seung-Heui;Sung, Nack-Do;Myung, Pyung-Keun;Jeon, Young-Koo;Lee, Chun-Bae
    • Korean journal of applied entomology
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    • v.24 no.4 s.65
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    • pp.231-238
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    • 1986
  • Molecular orbital theoretical study on the stability of conformations and chemical reactivity of 0,0-diethylphenylphosphate derivatives were carried out by EHT and CNDO/2 molecular orbital calculation method. The results shown that the dipole moment(${\mu}$) and total energies of the ${\theta}=90^{\circ}$ conformer were ${\mu}=3.185D\;&\;E_t=-162.6479(au)$ and also that of the ${\theta}=0^{\circ}$ conformer were ${\mu}=5.596D\;&\;E_t=-162.4013(au)$, respectively. Therefore, the values of ${\mu}\;&\;E_t$ of the ${\theta}=90^{\circ}$ conformer were much smaller than that of the ${\theta}=0^{\circ}$ conformer. The form with angle of rotation ${\theta}=90^{\circ}$ of phenyl ring was shown to be most stable and this was interpreted in terms of electrostatic and steric effect. 0,0-diethylphenylphosphate derivatives are predicted to increase both charge and orbital controlled $SN_2$ reactivity of the electron withdrawing substituent reduces the HOMO & LUMO energy, while the electron withdrawing substituent due to increase in positive charge of phosphorus atom of phosphate molecule.

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Analysis of Multiple Pesticide Residues in Apples and Pears Using Gas-Liquid Chromatography (Gas-Liquid Chromatography를 이용한 사과 및 배 중의 농약 다성분 잔류분석법)

  • Park, Ju-Hwang;Kim, Taek-Kyum;Oh, Chang-Hwan;Kim, Jeong-Han;Lee, Young-Deuk;Kim, Jang-Eok
    • Korean Journal of Environmental Agriculture
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    • v.23 no.3
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    • pp.148-157
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    • 2004
  • A rapid analytical method was developed to determine multiple pesticide residues in apples and pears using gas-liquid chromatography (GLC). The samples were extracted with water-miscible solvents and purified by cleanup procedures serially comprising liquid-liquid partition and solid-phase extraction (SPE). Each analyte was separated and determined by a high-resolution GLC equipped with electron-capture detector (ECD) and nitrogen-phosphorous detector (NPD). A total of 196 pesticides, which were previously classified into 5 groups each for ECD and NPD based on their retention behaviors on the capillary column and responses to the detector, were subjected to the recovery experiment. In compliance with the analytical criteria, 70 to 120% of recovery and less than 20% relative standard deviation the proposed method could be successfully applied to analyze 136 and 133 pesticide residues in apples and pears, respectively, which enabled not only rapid screening but quantitation of the residues. Even though less reliability was resulted from unacceptable recovery range, rest of pesticides including 43 and 45 analyzes in apples and pears, could be also detected for their identity. The proposed method fliled to cover 17 and 18 pesticides for apples and pears, which mostly showed high polarity or heat-lability but could be suitable far fast surveilance or monitoring of fruit harvests.