• Journal of the Korean Society of School Health
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• v.19 no.1
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• pp.79-88
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• 2006

Purpose : To identify general characteristics of school personnel with recent fatigue which was the most frequent symptom among subjective symptoms and to explore fatigue-related factors by evaluating physical and perceived health status, life style, and symptoms through data mining techniques. Methods : We collected a data of the 1,147(male 545, female 602) who were elementary, middle, or high school personnel, answered a questionnaire, and received physical examination in Seoul School Health Center from September to November in 2000. And we investigated the differences between fatigue group and non-fatigue group for demographic characteristics, physical health status, perceived health status, symptoms, and laboratory values by frequency, chi-square test, t-test, or simple logistic regression analysis by SAS package 8.1, and then selected significant variables as input variables of a decision tree analysis of CART model by SAS E-miner. Results : In general characteristics, the fatigue consisted of 41.1%(male 35.2%, female 46.4%) among 1,147 school personnel. In classical statistics, factors related with fatigue were female, lower means of systolic and diastolic pressure, young age, personnel in middle school, irregular eating habit, no exercise a week or less than 30minutes exercise a day, perception of unhealthy status, and subjective symptoms including short of breath at exercise. In simple logistic regression to examine the relationship between selected independent variables and fatigue as a dependent variable, the odds ratio of gender (female vs male) was 1.58 times, and young age ( 20s vs 60s) 20.67 times, and middle vs high school personnel 1.86 times. However, we mined combined several characteristics by SAS-E miner. In CART model, if health perception was healthy, and age was >= 37.5 years, the proportion of the fatigue was only 19.3%. but if health perception was not healthy and symptom was severe 'short of breath' during exercise and age was < 53.5 years, and BMI was >= 22.69, the proportion of the fatigue was up to 84.8%. Conclusions : The fatigue consisted of 41.1%(male 35.2%, female 46.4%). In classical statistics, fatigue-related factors among school personnel were young age, female gender, perceived unhealthy status, subjective physical symptoms, poor life-style, and lower blood pressure rather than only physical health status. However, in data mining, if health perception was healthy and age was >= 37.5 years, the proportion of the fatigue was only 19.3%. but if health perception was not healthy and symptom was severe 'short of breath' during exercise and age was < 53.5 years, and BMI was >= 22.69, the proportion of the fatigue was up to 84.8%.

• Applied Chemistry for Engineering
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• v.19 no.4
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• pp.421-426
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• 2008

Multi-walled carbon nanotube/polystyrene (MWCNT/PS) composites with various MWCNT contents were prepared by using a solution process with an aid of surfactant. Particularly, PS's with 3 different molecular weights (${\bar{M}}_n$ = 101500 g/mole for PS-1, ${\bar{M}}_n$ = 89900 g/mole for PS-2, and ${\bar{M}}_n$ = 85000 g/mole for PS-3) were used in this study. Thermal behavior of these composites was examined by using an oscillator rheometer at $210^{\circ}C$ and $180^{\circ}C$, of above and below the critical flow temperature ($T_{cf}{\sim}195^{\circ}C$) of PS matrix, respectively. The storage and loss modulus, and the complex viscosity of these composites increased with increasing MWCNT content at both temperatures. Largest increases in the frequency-dependent moduli and complex viscosity were observed between 2 wt% and 5 wt% of MWCNTs at $210^{\circ}C$ and $180^{\circ}C$. Only the composite at $210^{\circ}C$ showed the rheological phase transition from a viscous-dominant to an elastic-dominant behavior of the composites at a certain MWCNT content. The MWCNT content at the rheological phase transition of MWCNT/PS composites generally increased with decreasing molecular weight of PS, and was measured to be 3.5 wt% for MWCNT/PS-1, 3.2 wt% for MWCNT/PS-2, and 3.0 wt% for MWCNT/PS-3 composites.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.4
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• pp.615-621
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• 2016

This study examines whether there is agency cost in a public R&D subsidy program by applying agency theory. If there is agency cost, the composition ratio of the government subsidy and the firm's own R&D fund would have a significant (-) effect on technological performance. Companies that received a public R&D subsidy in Korea from 2000 to 2009 were selected as a sample. Frequency analysis and multiple regression analysis were used. The independent variables was the ratio of public R&D subsidy cost to the Firm's own R&D cost, and the dependent variables were the number of patent applications and the number of patents registered. The control variables were firm size and R&D cost. The results show that there are agency problems in the government-sponsored R&D system. A future study is needed to examine how much agency problems deteriorate the efficiency of the system.

• The Korean Journal of Physiology
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• v.28 no.1
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• pp.37-50
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• 1994

Synthetic potassium channel openers (KCOs) are agents capable of opening K-channels in excitable cells. These agents are known to have their maximal potency in the smooth muscle tissue, especially in the vascular smooth muscle. Much attention has been focused on the type of K-channel that is responsible for mediating the effects of KCOs. As the KCO-induced changes are antagonized by glibenclamide, an $K_{ATP}$ (ATP-sensitive K-channel) blocker in the pancreatic ${\beta}-cell,\;K_{ATP}$ was suggested to be the channel responsible. However, there also are many results in favor of other types of K-channel $$(maxi-K,\;small\;conductance\;K_{Ca,}\; SK_{ATP}) mediating the effects of KCOs. Effects of lemakalim, (-)enantiomer of cromakalim (BRL 34915), on the spontaneous contractions and slow waves, were investigated in the antral circular muscle of the guinea-pig stomach. Membrane currents and the effects on membrane currents and single channel activities were also measured in single smooth muscle cells and excised membrane patches by using the patch clamp method. Lemakalim induced hyperpolarization and inhibited spontaneous contractions in a dose-dependent manner. These effects were blocked by glibenclamide and low concentrations of tetraethyl ammonium (< mM). Glibenclamide blocked the effect of lemakalim on the membrane potential and slow waves. The mechanoinhibitory effect of lemakalim was blocked by pretreatment with glibenclamide. In a whole ceIl patch clamp condition, lemakalim largely increased outward K currents. These outward K currents were blocked by TEA, glibenclamide and a high concentration of intracelIular EGTA (10 mM). Volatage-gated Ca currents were not affected by lemakalim. In inside-out patch clamp experiments, lemakalim increased the opening frequency of the large conductance $Ca^{2+}-activated$ K channels $(BK_{Ca},\;Maxi-K).$ From these results, it is suggested that lemakalim induces hyperpolarization by opening K-channels which are sensitive to internal Ca and such a hyperpolarization leads to the inhibition of the spontaneous contraction.

• Journal of Broadcast Engineering
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• v.21 no.2
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• pp.169-179
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• 2016

Recently, MPEG-H has been standardizing for a multimedia coder in UHDTV (Ultra-High-Definition TV). Thus, the demand for not only channel-based audio contents but also object-based audio contents is more increasing, which results in developing a new technique of converting channel-based audio contents to object-based ones. In this paper, a non-uniform linear microphone array based source separation method is proposed for realizing such conversion. The proposed method first analyzes the arrival time differences of input audio sources to each of the microphones, and the spectral magnitudes of each sound source are estimated at the horizontal directions based on the analyzed time differences. In order to demonstrate the effectiveness of the proposed method, objective performance measures of the proposed method are compared with those of conventional methods such as an MVDR (Minimum Variance Distortionless Response) beamformer and an ICA (Independent Component Analysis) method. As a result, it is shown that the proposed separation method has better separation performance than the conventional separation methods.

• Korean Journal of Food Science and Technology
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• v.27 no.6
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• pp.1003-1007
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• 1995

The effect of brown rice extract on mitomycin C(MMC)-induced chromosome aberration was examined in cultured Chinese hamster lung(CHL) cells, after induction of chromosome aberration and mitotic index in CHL cells cultured with MMC were observed. There were no significant differences between mitotic indices of CHL cells treated with DMSO, and MMC and brown rice extract. The frequency of chromosome aberration showed dose-dependent relationship in CHL cells treated with $0.2{\sim}3.0\;{\mu}g$/assay of MMC. But chromosome aberrations could not be assayed Our to cytotoxicity of MMC when its concentrations were above $3.0\;{\mu}g$/assay. Chromatid type, especially gap and break, of chromosome aberration were most frequently observed. When CHL cells treated with $2.0\;{\mu}g$/assay of MMC and brown rice extracts of concentration ranging $0.75{\sim}10.0\;{\mu}g$/assay were incubated, frequencies of chromosome aberration induced by MMC were significantly decreased at above concentrations(p<0.01, p<0.05). As concentration of brown rice extract was increased, frequencies of chromosome aberration was decreased $7{\sim}30%$, in some irregularity.

• Journal of dental hygiene science
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• v.15 no.6
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• pp.775-785
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• 2015

The purpose of this study is to verify factors affecting the use of dental hygiene care products in adults. The study used a nationally representative sample of Koreans (2013 Korea National Health and Nutrition Examination Survey) aged 19 years over (n=4,839). Dependent variable was frequency of tooth brushing per day, use of dental floss, use of interdental brush and use of mouth rinse. Independent variable was sociodemographic factors, health behaviors, perceived health and oral health conditions. The chi-square test and logistic regression analysis were performed to identify the factors affecting the use of dental hygiene care products. All analyses were performed using PASW Statistics version 18.0. Resulting of chi-square test, the use of oral hygiene care products was statistically significant with gender, age, education level, household income, marital status, dental utilization, dental examination. Resulting of logistic regression, in female, the higher the education level was identified as common factors for variables in use of dental hygiene care products. Dental hygienist among dental professionals should play an important role as contributor to the national oral health promotion that recognizes the impact of each factor by refining dental hygiene care products and reflect personal characteristics and preferences through the oral health educational media and program development.

• Molecules and Cells
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• v.20 no.2
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• pp.235-240
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• 2005

Extracts of pine needles (Pinus densiflora Sieb. et Zucc.) have diverse physiological and pharmacological actions. In this study we show that pine needle extract alters pacemaker currents in interstitial cells of Cajal (ICC) by modulating ATP-sensitive $K^+$ channels and that this effect is mediated by prostaglandins. In whole cell patches at $30^{\circ}C$, ICC generated spontaneous pacemaker potentials in the current clamp mode (I = 0), and inward currents (pacemaker currents) in the voltage clamp mode at a holding potential of -70 mV. Pine needle extract hyperpolarized the membrane potential, and in voltage clamp mode decreased both the frequency and amplitude of the pacemaker currents, and increased the resting currents in the outward direction. It also inhibited the pacemaker currents in a dose-dependent manner. Because the effects of pine needle extract on pacemaker currents were the same as those of pinacidil (an ATP-sensitive $K^+$ channel opener) we tested the effect of glibenclamide (an ATP-sensitive $K^+$ channels blocker) on ICC exposed to pine needle extract. The effects of pine needle extract on pacemaker currents were blocked by glibenclamide. To see whether production of prostaglandins (PGs) is involved in the inhibitory effect of pine needle extract on pacemaker currents, we tested the effects of naproxen, a non-selective cyclooxygenase (COX-1 and COX-2) inhibitor, and AH6809, a prostaglandin EP1 and EP2 receptor antagonist. Naproxen and AH6809 blocked the inhibitory effects of pine needle extract on ICC. These results indicate that pine needle extract inhibits the pacemaker currents of ICC by activating ATP-sensitive $K^+$ channels via the production of PGs.

• Journal of the Korean association of regional geographers
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• v.21 no.2
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• pp.379-393
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• 2015

The fire damage has been increased as the frequency of fire incidence decreases with increasing in death and economic loss. Local governments are dependent on the activities of fire-fighters with crude preparedness and prevention for fire incidence. Most of researches on fire safety have focused on descriptive statistics which show general trends in fire incidence and condition. Here we tried to make a mutual causal model for fire damage, to make three big hypotheses with laying three small hypotheses under each big hypothesis. Five years statistics from public domains in the form of hardcopy or softcopy were collected and fifteen independent variables were selected to explain the number of death, the number of fire incidence and the amount of economic loss from fire incidence. The significances of statistics are different among the regional characteristics. The hypotheses were partially rejected and the meanings of rejected factors will refresh the tentative prejudice. It is necessary to revise the principle that the number of population and size of area are regarded as the most important criteria to allocate resources for fire control and to have the criteria flexible with results of our research such as the number of the weak to fire disaster.

• Korean Journal of Agricultural and Forest Meteorology
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• v.14 no.4
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• pp.155-160
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• 2012

This study was conducted to develop a practical method for estimating the extremes of minimum air temperature with given return-period based on the frequency distribution of daily minimum air temperature in January. Daily temperature data were collected from 61 meteorological observatories country-wide from 1961 to 2010. Most of daily minimum temperature in January could be represented by a normal-distribution, so it is possible to predict stochastically the lowest temperature by the mean and standard deviation. We developed a quadratic function to estimate standard deviation in terms of daily minimum temperature in January. Also, we introduced a coefficient which can be used to predict an extreme of minimum temperature with mean and standard deviation, and is dependent on return-periods. Using this method, we were able to reproduce the past 30-year extremes with an error of 1.1 on average and 5.3 in the worst case.